A pathway in primate brain for internal monitoring of movements.

Journal Article (Journal Article)

It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem to frontal cortex might carry corollary discharge signals. We found that neuronal activity in this pathway encodes upcoming eye movements and that inactivating the pathway impairs sequential eye movements consistent with loss of corollary discharge without affecting single eye movements. These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals.

Full Text

Duke Authors

Sommer, Marc A.

Cited Authors

Sommer, MA; Wurtz, RH

Published Date

May 2002

Published In

Science (New York, N.Y.)

Volume / Issue

296 / 5572

Start / End Page

1480 - 1482

PubMed ID

12029137

Pubmed Central ID

12029137

Electronic International Standard Serial Number (EISSN)

1095-9203

International Standard Serial Number (ISSN)

0036-8075

Digital Object Identifier (DOI)

10.1126/science.1069590

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