A pathway in primate brain for internal monitoring of movements.

Journal Article (Journal Article)

It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem to frontal cortex might carry corollary discharge signals. We found that neuronal activity in this pathway encodes upcoming eye movements and that inactivating the pathway impairs sequential eye movements consistent with loss of corollary discharge without affecting single eye movements. These results identify a pathway in the brain of the primate Macaca mulatta that conveys corollary discharge signals.

Full Text

Duke Authors

Cited Authors

  • Sommer, MA; Wurtz, RH

Published Date

  • May 2002

Published In

Volume / Issue

  • 296 / 5572

Start / End Page

  • 1480 - 1482

PubMed ID

  • 12029137

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.1069590


  • eng