New ways to observe and control dynamics

Journal Article

We summarize recent progress aimed at observing biochemical and biological dynamics using confocal microscopy with 3D spatial resolution down to a few hundred nm and temporal resolution to 15 fs. We also review recent control of population dynamics using tailored ultrafast pulses, i.e. quantum control. Progress is described for i) feedback control, ii) multiphoton control, and iii) molecular π pulse. Finally, using ultrafast light pulses, we combine confocal and quantum control techniques to produce a new way to measure the microscopic chemical environment, in this case pH, potentially with a spatial resolution of a few hundred nanometers.

Full Text

Duke Authors

Cited Authors

  • Wilson, KR; Bardeen, C; Barty, CPJ; Brakenhoff, GJ; Buist, AH; Cao, J; Carpenter, SD; Che, JW; Fittinghoff, DN; Müller, M; Squier, JA; Warren, WS; Weber, PM; Yakovlev, VV

Published Date

  • December 1, 1998

Published In

Volume / Issue

  • 3273 /

Start / End Page

  • 214 - 218

International Standard Serial Number (ISSN)

  • 0277-786X

Digital Object Identifier (DOI)

  • 10.1117/12.306130

Citation Source

  • Scopus