New ways to observe and control dynamics
We summarize recent progress aimed at observing biochemical and biological dynamics using confocal microscopy with 3D spatial resolution down to a few hundred nm and temporal resolution to 15 fs. We also review recent control of population dynamics using tailored ultrafast pulses, i.e. quantum control. Progress is described for i) feedback control, ii) multiphoton control, and iii) molecular π pulse. Finally, using ultrafast light pulses, we combine confocal and quantum control techniques to produce a new way to measure the microscopic chemical environment, in this case pH, potentially with a spatial resolution of a few hundred nanometers.
Wilson, KR; Bardeen, C; Barty, CPJ; Brakenhoff, GJ; Buist, AH; Cao, J; Carpenter, SD; Che, JW; Fittinghoff, DN; Müller, M; Squier, JA; Warren, WS; Weber, PM; Yakovlev, VV
Volume / Issue
Start / End Page
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)