Overview
Our work focuses on the design and application of what might best be called novel pulsed techniques, using controlled radiation fields to alter dynamics. The heart of the work is chemical physics, and most of what we do is ultrafast laser spectroscopy or nuclear magnetic resonance. It generally involves an intimate mixture of theory and experiment: recent publications are roughly an equal mix of pencil- and-paper theory, computer calculations with our workstations, and experiments. Collaborations also play an important role, particularly for medical applications.
Current Appointments & Affiliations
James B. Duke Distinguished Professor of Chemistry
·
2006 - Present
Chemistry,
Trinity College of Arts & Sciences
Professor of Chemistry
·
2005 - Present
Chemistry,
Trinity College of Arts & Sciences
Professor of Radiology
·
2005 - Present
Radiology,
Clinical Science Departments
Professor of Biomedical Engineering
·
2011 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor of Physics
·
2015 - Present
Physics,
Trinity College of Arts & Sciences
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Exchange-selective excitation pulses for dynamic magnetic resonance.
Journal Article Science advances · February 2025 Coherent evolution is punctuated by dynamical processes such as chemical exchange, conformational transformation, or site hopping in many important problems ranging from biomolecular function to ion trap quantum computation. One well-explored example is nu ... Full text CiteAlexander Pines and the end of an era.
Journal Article Science advances · February 2025 Full text CiteThe frontiers of chemical imaging.
Journal Article Science advances · December 2024 Full text CiteRecent Grants
Medical Scientist Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027Detecting missed metastases from nominally early-stage melanomas with pump-probe microscopy
ResearchPrincipal Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2023 - 2026Improving Accuracy of Next-Generation Microscopy for Early Stage Metastatic Melanoma Detection
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2024 - 2025View All Grants
Education, Training & Certifications
University of California, Berkeley ·
1980
Ph.D.
University of California, Berkeley ·
1979
M.S.