How is the mouse segmented?
During mouse embryogenesis the vertebrae, ribs, muscles and dermis are all derived from about 65 paired blocks of mesodermal cells - the somites - which are laid down sequentially along the body axis. This pattern of body segmentation is compared with that found in other organisms, in particular Drosophila. Mouse mutants have been described which have defects in somite patter but it seems that none show homeotic-like switches in segment identity. © 1985.
Hogan, B; Holland, P; Schofield, P
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