Role of natural product diversity in chemical biology.

Journal Article (Review;Journal Article)

Through the natural selection process, natural products possess a unique and vast chemical diversity and have been evolved for optimal interactions with biological macromolecules. Owing to their diversity, target affinity, and specificity, natural products have demonstrated enormous potential as modulators of biomolecular function, been an essential source for drug discovery, and provided design principles for combinatorial library development.

Full Text

Published version (via Digital Object Identifier)
Pubmed Central version

Duke Authors

Hong, Jiyong

Cited Authors

Hong, J

Published Date

June 2011

Published In

Current Opinion in Chemical Biology

Volume / Issue

15 / 3

Start / End Page

350 - 354

PubMed ID

21489856

Pubmed Central ID

PMC3110584

Electronic International Standard Serial Number (EISSN)

1879-0402

International Standard Serial Number (ISSN)

1367-5931

Digital Object Identifier (DOI)

10.1016/j.cbpa.2011.03.004

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