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MR imaging of myocardial perfusion and viability.

Publication ,  Journal Article
Wagner, A; Mahrholdt, H; Sechtem, U; Kim, RJ; Judd, RM
Published in: Magn Reson Imaging Clin N Am
February 2003

CMR is a rapidly developing new modality with applications in clinical cardiology for detection and assessment of myocardial ischemia and viability. CMR perfusion results for the detection of ischemia in comparison with stress echocardiography and scintigraphic techniques are reasonable, but all the studies reported to date have been conduced in selected patients. Larger studies in patient populations reflecting a broader spectrum of disease are necessary before perfusion CMR can be envisaged as a clinically reliable and robust diagnostic tool. Other CMR techniques provide a variety of novel methods of obtaining information on postischemic viability. Signs of viability that can be observed by CMR are the absence of late gadolinium-based contrast enhancement in a myocardial region involved in a recent infarct, any sign of wall thickening at rest (which is detectable with high accuracy by CMR), wall thickening after stimulation by low-dose dobutamine, and preserved wall thickness. Conversely, myocardial necrosis is characterized by signal enhancement of the infarct area after injection of Gd-DTPA, reduced wall thickness in chronic infarcts, and absence of a contractile reserve during dobutamine stimulation. Dobutamine CMR and late enhancement contrast-enhanced CMR predict contractile improvement after revascularization.

Duke Scholars

Published In

Magn Reson Imaging Clin N Am

DOI

ISSN

1064-9689

Publication Date

February 2003

Volume

11

Issue

1

Start / End Page

49 / 66

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Myocardial Ischemia
  • Myocardial Contraction
  • Magnetic Resonance Imaging
  • Humans
  • Contrast Media
  • 4003 Biomedical engineering
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wagner, A., Mahrholdt, H., Sechtem, U., Kim, R. J., & Judd, R. M. (2003). MR imaging of myocardial perfusion and viability. Magn Reson Imaging Clin N Am, 11(1), 49–66. https://doi.org/10.1016/s1064-9689(02)00048-x
Wagner, Anja, Heiko Mahrholdt, Udo Sechtem, Raymond J. Kim, and Robert M. Judd. “MR imaging of myocardial perfusion and viability.Magn Reson Imaging Clin N Am 11, no. 1 (February 2003): 49–66. https://doi.org/10.1016/s1064-9689(02)00048-x.
Wagner A, Mahrholdt H, Sechtem U, Kim RJ, Judd RM. MR imaging of myocardial perfusion and viability. Magn Reson Imaging Clin N Am. 2003 Feb;11(1):49–66.
Wagner, Anja, et al. “MR imaging of myocardial perfusion and viability.Magn Reson Imaging Clin N Am, vol. 11, no. 1, Feb. 2003, pp. 49–66. Pubmed, doi:10.1016/s1064-9689(02)00048-x.
Wagner A, Mahrholdt H, Sechtem U, Kim RJ, Judd RM. MR imaging of myocardial perfusion and viability. Magn Reson Imaging Clin N Am. 2003 Feb;11(1):49–66.
Journal cover image

Published In

Magn Reson Imaging Clin N Am

DOI

ISSN

1064-9689

Publication Date

February 2003

Volume

11

Issue

1

Start / End Page

49 / 66

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Myocardial Ischemia
  • Myocardial Contraction
  • Magnetic Resonance Imaging
  • Humans
  • Contrast Media
  • 4003 Biomedical engineering
  • 3202 Clinical sciences