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RNA recognition: towards identifying determinants of specificity.

Publication ,  Journal Article
Kenan, DJ; Query, CC; Keene, JD
Published in: Trends Biochem Sci
June 1991

Members of a family of proteins containing a conserved approximately 80-amino acid RNA recognition motif (RRM) bind specifically to a wide variety of RNA molecules. Structural studies, in combination with sequence alignments, indicate the structural context of both conserved and non-conserved elements in the motif. These analyses suggest that all RRM proteins share a common fold and a similar protein-RNA interface, and that non-conserved residues contribute additional contacts for sequence-specific RNA recognition.

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Published In

Trends Biochem Sci

DOI

ISSN

0968-0004

Publication Date

June 1991

Volume

16

Issue

6

Start / End Page

214 / 220

Location

England

Related Subject Headings

  • RNA-Binding Proteins
  • RNA
  • Developmental Biology
  • Carrier Proteins
  • Amino Acid Sequence
  • 3404 Medicinal and biomolecular chemistry
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Kenan, D. J., Query, C. C., & Keene, J. D. (1991). RNA recognition: towards identifying determinants of specificity. Trends Biochem Sci, 16(6), 214–220. https://doi.org/10.1016/0968-0004(91)90088-d
Kenan, D. J., C. C. Query, and J. D. Keene. “RNA recognition: towards identifying determinants of specificity.Trends Biochem Sci 16, no. 6 (June 1991): 214–20. https://doi.org/10.1016/0968-0004(91)90088-d.
Kenan DJ, Query CC, Keene JD. RNA recognition: towards identifying determinants of specificity. Trends Biochem Sci. 1991 Jun;16(6):214–20.
Kenan, D. J., et al. “RNA recognition: towards identifying determinants of specificity.Trends Biochem Sci, vol. 16, no. 6, June 1991, pp. 214–20. Pubmed, doi:10.1016/0968-0004(91)90088-d.
Kenan DJ, Query CC, Keene JD. RNA recognition: towards identifying determinants of specificity. Trends Biochem Sci. 1991 Jun;16(6):214–220.
Journal cover image

Published In

Trends Biochem Sci

DOI

ISSN

0968-0004

Publication Date

June 1991

Volume

16

Issue

6

Start / End Page

214 / 220

Location

England

Related Subject Headings

  • RNA-Binding Proteins
  • RNA
  • Developmental Biology
  • Carrier Proteins
  • Amino Acid Sequence
  • 3404 Medicinal and biomolecular chemistry
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences