Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.
Publication
, Journal Article
Zerhouni-Layachi, B; Husain, M; Ross, MJ; Marras, D; Sunamoto, M; Liu, X; Klotman, PE; Klotman, ME
Published in: AIDS
February 28, 2006
The phenotype of HIV-1 gp120 envelope derived from renal epithelium and peripheral blood mononuclear cells (PBMC) of patients with HIV-associated nephropathy was investigated in vitro. Chimeric viruses were derived from kidney or blood and used to infect primary CD4+T cells, cell lines expressing single co-receptors and a renal epithelial cell line HPT-1. HIV-1 variants derived from renal epithelium were dual tropic whereas simultaneously derived viruses from PBMC were R5-tropic. Utilization of alternative co-receptors CCR3, BONZO and BOB, also differed.
Duke Scholars
Published In
AIDS
DOI
ISSN
0269-9370
Publication Date
February 28, 2006
Volume
20
Issue
4
Start / End Page
621 / 624
Location
England
Related Subject Headings
- Virus Replication
- Virology
- Tropism
- Receptors, Virus
- Receptors, G-Protein-Coupled
- Receptors, Cytokine
- Receptors, Chemokine
- Receptors, CXCR6
- Receptors, CCR3
- Phenotype
Citation
APA
Chicago
ICMJE
MLA
NLM
Zerhouni-Layachi, B., Husain, M., Ross, M. J., Marras, D., Sunamoto, M., Liu, X., … Klotman, M. E. (2006). Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. AIDS, 20(4), 621–624. https://doi.org/10.1097/01.aids.0000210618.68083.8e
Zerhouni-Layachi, Bouchra, Mohammad Husain, Michael J. Ross, Daniele Marras, Masaaki Sunamoto, Xinyan Liu, Paul E. Klotman, and Mary E. Klotman. “Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.” AIDS 20, no. 4 (February 28, 2006): 621–24. https://doi.org/10.1097/01.aids.0000210618.68083.8e.
Zerhouni-Layachi B, Husain M, Ross MJ, Marras D, Sunamoto M, Liu X, et al. Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. AIDS. 2006 Feb 28;20(4):621–4.
Zerhouni-Layachi, Bouchra, et al. “Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.” AIDS, vol. 20, no. 4, Feb. 2006, pp. 621–24. Pubmed, doi:10.1097/01.aids.0000210618.68083.8e.
Zerhouni-Layachi B, Husain M, Ross MJ, Marras D, Sunamoto M, Liu X, Klotman PE, Klotman ME. Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. AIDS. 2006 Feb 28;20(4):621–624.
Published In
AIDS
DOI
ISSN
0269-9370
Publication Date
February 28, 2006
Volume
20
Issue
4
Start / End Page
621 / 624
Location
England
Related Subject Headings
- Virus Replication
- Virology
- Tropism
- Receptors, Virus
- Receptors, G-Protein-Coupled
- Receptors, Cytokine
- Receptors, Chemokine
- Receptors, CXCR6
- Receptors, CCR3
- Phenotype