Tribulin in post-traumatic stress disorder.

Journal Article (Journal Article)

Tribulin (endogenous monoamine oxidase inhibitor/benzodiazepine receptor binding inhibitor) output was measured in the urine of 18 patients with post-traumatic stress disorder (PTSD) and 13 controls. The level of the two inhibitory activities was highly significantly correlated in the group as a whole. There was no difference between output of either inhibitor in patients and controls. However, when the PTSD group was subdivided according to various psychometric ratings, a pattern of output did emerge. Levels of both inhibitory activities were higher in agitated compared with non-agitated subjects, and lower in extroverts compared with introverts. This finding supports the view that tribulin output is raised in conditions of greater arousal.

Full Text

Duke Authors

Cited Authors

  • Davidson, J; Glover, V; Clow, A; Kudler, H; Meador, K; Sandler, M

Published Date

  • November 1988

Published In

Volume / Issue

  • 18 / 4

Start / End Page

  • 833 - 836

PubMed ID

  • 3270828

International Standard Serial Number (ISSN)

  • 0033-2917

Digital Object Identifier (DOI)

  • 10.1017/s0033291700009764


  • eng

Conference Location

  • England