National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: the need for pediatric-specific long-term follow-up guidelines.

Journal Article (Journal Article)

Existing standards for screening and management of late effects occurring in children who have undergone hematopoietic cell transplantation (HCT) include recommendations from pediatric cancer networks and consensus guidelines from adult-oriented transplantation societies applicable to all HCT recipients. Although these approaches have significant merit, they are not pediatric HCT-focused, and they do not address post-HCT challenges faced by children with complex nonmalignant disorders. In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines for post-HCT screening and management would be beneficial to the long-term health of these patients and would promote late effects research in this field. Our panel of late effects experts also provides recommendations for follow-up and therapy of selected post-HCT organ and endocrine complications in pediatric patients.

Full Text

Duke Authors

Cited Authors

  • Pulsipher, MA; Skinner, R; McDonald, GB; Hingorani, S; Armenian, SH; Cooke, KR; Gracia, C; Petryk, A; Bhatia, S; Bunin, N; Nieder, ML; Dvorak, CC; Sung, L; Sanders, JE; Kurtzberg, J; Baker, KS

Published Date

  • March 2012

Published In

Volume / Issue

  • 18 / 3

Start / End Page

  • 334 - 347

PubMed ID

  • 22248713

Pubmed Central ID

  • PMC3281504

Electronic International Standard Serial Number (EISSN)

  • 1523-6536

Digital Object Identifier (DOI)

  • 10.1016/j.bbmt.2012.01.003


  • eng

Conference Location

  • United States