Amygdala activation to sad pictures during high-field (4 tesla) functional magnetic resonance imaging.

Journal Article

Fear-related processing in the amygdala has been well documented, but its role in signaling other emotions remains controversial. The authors recovered signal loss in the amygdala at high-field strength using an inward spiral pulse sequence and probed its response to pictures varying in their degree of portrayed sadness. These pictures were presented as intermittent task-irrelevant distractors during a concurrent visual oddball task. Relative to neutral distractors, sad distractors elicited greater activation along ventral brain regions, including the amygdala, fusiform gyrus, and inferior frontal gyrus. In contrast, oddball targets engaged dorsal sectors of frontal, parietal, and cingulate cortices. The amygdala's role in emotional evaluation thus extends to images of grief and despair as well as to those depicting violence and threat.

Full Text

Duke Authors

Cited Authors

  • Wang, L; McCarthy, G; Song, AW; Labar, KS

Published Date

  • March 2005

Published In

Volume / Issue

  • 5 / 1

Start / End Page

  • 12 - 22

PubMed ID

  • 15755216

International Standard Serial Number (ISSN)

  • 1528-3542

Digital Object Identifier (DOI)

  • 10.1037/1528-3542.5.1.12

Language

  • eng

Conference Location

  • United States