Overview
The research in our lab is concerned with advancing structural and functional MRI methodologies (e.g. fast and high-resolution imaging techniques) for human brain imaging. We also aim to improve our understanding of functional brain signals, including spatiotemporal characterizations of the blood oxygenation level dependent contrast and alternative contrast mechanisms that are more directly linked to the neuronal activities. Additional effort is invested in applying and validating the developed methods to study human functional neuroanatomy.
Current Appointments & Affiliations
Professor in Radiology
·
2006 - Present
Radiology,
Clinical Science Departments
Director of the Center for Brain Imaging and Analysis
·
2006 - Present
Duke-UNC Brain Imaging and Analysis Center,
Institutes and Centers
Professor of Biomedical Engineering
·
2006 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor in Neurobiology
·
2007 - Present
Neurobiology,
Basic Science Departments
Professor in Psychiatry and Behavioral Sciences
·
2021 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Faculty Network Member of the Duke Institute for Brain Sciences
·
2008 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Publications
Higher spatial resolution diffusion-weighted imaging improves characterization of white matter disconnection in Alzheimer's disease.
Journal Article Imaging Neurosci (Camb) · 2026 In addition to the accumulation of neuropathologies (i.e., amyloid beta, neurofibrillary tangles), Alzheimer's disease (AD) is associated with the degradation of white matter (WM) structural pathways that connect distributed brain regions. However, previou ... Full text Open Access Link to item CiteThe Consortium for Clarity in ADRD Research Through Imaging (CLARiTI): Overview of consortium sites and anticipated enrollment.
Journal Article Alzheimers Dement · November 2025 INTRODUCTION: The Consortium for Clarity in Alzheimer's disease related dementias (ADRD) Research Through Imaging (CLARiTI) is a study that aims to collect standardized imaging and plasma biomarkers on 2000 Clinical Core participants enrolled across all Al ... Full text Link to item CiteStudy Protocol: Single-Blinded, Controlled, Clinical Trial Evaluating the Feasibility of Spinal Cord Stimulation for Improving Neuropathic Pain and Rehabilitation Outcomes in Patients With Thoracic Spinal Cord Injury.
Journal Article Neurosurg Pract · June 2025 BACKGROUND AND OBJECTIVES: Traumatic thoracic spinal cord injury (SCI) is complicated by chronic neuropathic pain and neurological deficits including bowel and bladder dysfunction. Treatment with spinal cord stimulation (SCS) has demonstrated possible util ... Full text Link to item CiteRecent Grants
Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029Integrated RF/Shim/WiFi Coil Array for High-Resolution Diffusion MRI in the Brain and Spinal Cord
ResearchPrincipal Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2028Wireless MRI with a stand-alone, platform-independent wireless integrated radio-frequency/shim coil array and cloud-based data processing workflow
ResearchCo-Principal Investigator · Awarded by National Institute of Biomedical Imaging and Bioengineering · 2024 - 2028View All Grants
Education
Medical College of Wisconsin ·
1995
Ph.D.