Vagus nerve stimulation. A potential therapy for resistant depression?
Publication
, Journal Article
George, MS; Sackeim, HA; Marangell, LB; Husain, MM; Nahas, Z; Lisanby, SH; Ballenger, JC; Rush, AJ
Published in: Psychiatr Clin North Am
December 2000
VNS builds on a long history of investigating the relationship of autonomic signals to limbic and cortical function and is one of the newest methods to physically alter brain function. VNS is a clinically useful anticonvulsant therapy in treatment resistant patients with epilepsy, and pilot data suggest that it has potential as an antidepressant therapy. The known anatomic projections of the vagus nerve suggest that VNS also might have other neuropsychiatric applications. Additional research is needed to clarify the mechanisms of action of VNS and the potential clinical utility of this intriguing new somatic portal into the CNS.
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Published In
Psychiatr Clin North Am
DOI
ISSN
0193-953X
Publication Date
December 2000
Volume
23
Issue
4
Start / End Page
757 / 783
Location
United States
Related Subject Headings
- Vagus Nerve
- Treatment Outcome
- Solitary Nucleus
- Psychiatry
- Neural Pathways
- Humans
- Electric Stimulation Therapy
- Depressive Disorder, Major
- Brain Mapping
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
George, M. S., Sackeim, H. A., Marangell, L. B., Husain, M. M., Nahas, Z., Lisanby, S. H., … Rush, A. J. (2000). Vagus nerve stimulation. A potential therapy for resistant depression? Psychiatr Clin North Am, 23(4), 757–783. https://doi.org/10.1016/s0193-953x(05)70196-9
George, M. S., H. A. Sackeim, L. B. Marangell, M. M. Husain, Z. Nahas, S. H. Lisanby, J. C. Ballenger, and A. J. Rush. “Vagus nerve stimulation. A potential therapy for resistant depression?” Psychiatr Clin North Am 23, no. 4 (December 2000): 757–83. https://doi.org/10.1016/s0193-953x(05)70196-9.
George MS, Sackeim HA, Marangell LB, Husain MM, Nahas Z, Lisanby SH, et al. Vagus nerve stimulation. A potential therapy for resistant depression? Psychiatr Clin North Am. 2000 Dec;23(4):757–83.
George, M. S., et al. “Vagus nerve stimulation. A potential therapy for resistant depression?” Psychiatr Clin North Am, vol. 23, no. 4, Dec. 2000, pp. 757–83. Pubmed, doi:10.1016/s0193-953x(05)70196-9.
George MS, Sackeim HA, Marangell LB, Husain MM, Nahas Z, Lisanby SH, Ballenger JC, Rush AJ. Vagus nerve stimulation. A potential therapy for resistant depression? Psychiatr Clin North Am. 2000 Dec;23(4):757–783.
Published In
Psychiatr Clin North Am
DOI
ISSN
0193-953X
Publication Date
December 2000
Volume
23
Issue
4
Start / End Page
757 / 783
Location
United States
Related Subject Headings
- Vagus Nerve
- Treatment Outcome
- Solitary Nucleus
- Psychiatry
- Neural Pathways
- Humans
- Electric Stimulation Therapy
- Depressive Disorder, Major
- Brain Mapping
- 3202 Clinical sciences