Is cytomegalovirus a therapeutic target in glioblastoma?

Published

Journal Article

Several investigators have now demonstrated the expression of genes unique to cytomegalovirus (CMV) in malignant gliomas. Many of these genes promote oncogenesis, alter tumor microenvironment, and serve as immunologic targets. Is the level of CMV infection within tumor cells sufficient to drive important oncogenic or immunosuppressive processes? Can CMV serve as a target for therapeutic intervention?

Full Text

Duke Authors

Cited Authors

  • Sampson, JH; Mitchell, DA

Published Date

  • July 15, 2011

Published In

Volume / Issue

  • 17 / 14

Start / End Page

  • 4619 - 4621

PubMed ID

  • 21632859

Pubmed Central ID

  • 21632859

International Standard Serial Number (ISSN)

  • 1078-0432

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-11-0992

Language

  • eng

Conference Location

  • United States