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Is cytomegalovirus a therapeutic target in glioblastoma?

Publication ,  Journal Article
Sampson, JH; Mitchell, DA
Published in: Clin Cancer Res
July 15, 2011

Several investigators have now demonstrated the expression of genes unique to cytomegalovirus (CMV) in malignant gliomas. Many of these genes promote oncogenesis, alter tumor microenvironment, and serve as immunologic targets. Is the level of CMV infection within tumor cells sufficient to drive important oncogenic or immunosuppressive processes? Can CMV serve as a target for therapeutic intervention?

Duke Scholars

Published In

Clin Cancer Res

DOI

EISSN

1557-3265

Publication Date

July 15, 2011

Volume

17

Issue

14

Start / End Page

4619 / 4621

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Monocytes
  • Humans
  • Glioblastoma
  • Cytomegalovirus
  • Brain Neoplasms
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sampson, J. H., & Mitchell, D. A. (2011). Is cytomegalovirus a therapeutic target in glioblastoma? Clin Cancer Res, 17(14), 4619–4621. https://doi.org/10.1158/1078-0432.CCR-11-0992
Sampson, John H., and Duane A. Mitchell. “Is cytomegalovirus a therapeutic target in glioblastoma?Clin Cancer Res 17, no. 14 (July 15, 2011): 4619–21. https://doi.org/10.1158/1078-0432.CCR-11-0992.
Sampson JH, Mitchell DA. Is cytomegalovirus a therapeutic target in glioblastoma? Clin Cancer Res. 2011 Jul 15;17(14):4619–21.
Sampson, John H., and Duane A. Mitchell. “Is cytomegalovirus a therapeutic target in glioblastoma?Clin Cancer Res, vol. 17, no. 14, July 2011, pp. 4619–21. Pubmed, doi:10.1158/1078-0432.CCR-11-0992.
Sampson JH, Mitchell DA. Is cytomegalovirus a therapeutic target in glioblastoma? Clin Cancer Res. 2011 Jul 15;17(14):4619–4621.

Published In

Clin Cancer Res

DOI

EISSN

1557-3265

Publication Date

July 15, 2011

Volume

17

Issue

14

Start / End Page

4619 / 4621

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Monocytes
  • Humans
  • Glioblastoma
  • Cytomegalovirus
  • Brain Neoplasms
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis