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GP IIb-IIIa inhibitors administered upstream: evidence for improved outcomes with conventional and newer antithrombotic agents?

Publication ,  Journal Article
Tricoci, P; Newby, LK
Published in: Cardiol Rev
2008

Glycoprotein IIb-IIIa inhibitors provide the most benefit in patients with non-ST-elevation acute coronary syndromes and high-risk features and in those who undergo early invasive treatment. Current guidelines recommend glycoprotein IIb-IIIa inhibition in these patients but offer little guidance as to timing of initiation. Preliminary data suggest superior outcomes with upstream initiation (upon admission to a medical facility) compared with delayed initiation (in the catheterization laboratory, just before percutaneous coronary intervention). The availability of new antiplatelet and antithrombotic drugs renders even more complex the question of the best strategy.

Duke Scholars

Published In

Cardiol Rev

DOI

EISSN

1538-4683

Publication Date

2008

Volume

16

Issue

2

Start / End Page

89 / 94

Location

United States

Related Subject Headings

  • Thrombolytic Therapy
  • Practice Guidelines as Topic
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Patient Selection
  • Humans
  • Emergency Treatment
  • Drug Therapy, Combination
  • Drug Administration Schedule
  • Cardiovascular System & Hematology
 

Citation

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Tricoci, P., & Newby, L. K. (2008). GP IIb-IIIa inhibitors administered upstream: evidence for improved outcomes with conventional and newer antithrombotic agents? Cardiol Rev, 16(2), 89–94. https://doi.org/10.1097/CRD.0b013e31815e7213
Tricoci, Pierluigi, and L Kristin Newby. “GP IIb-IIIa inhibitors administered upstream: evidence for improved outcomes with conventional and newer antithrombotic agents?Cardiol Rev 16, no. 2 (2008): 89–94. https://doi.org/10.1097/CRD.0b013e31815e7213.
Tricoci, Pierluigi, and L. Kristin Newby. “GP IIb-IIIa inhibitors administered upstream: evidence for improved outcomes with conventional and newer antithrombotic agents?Cardiol Rev, vol. 16, no. 2, 2008, pp. 89–94. Pubmed, doi:10.1097/CRD.0b013e31815e7213.

Published In

Cardiol Rev

DOI

EISSN

1538-4683

Publication Date

2008

Volume

16

Issue

2

Start / End Page

89 / 94

Location

United States

Related Subject Headings

  • Thrombolytic Therapy
  • Practice Guidelines as Topic
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Patient Selection
  • Humans
  • Emergency Treatment
  • Drug Therapy, Combination
  • Drug Administration Schedule
  • Cardiovascular System & Hematology