Overview
Research Description
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
Current Appointments & Affiliations
Professor of Medicine
·
2011 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
1987 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
The assessment and management of patients with type 2 myocardial infarction: an international Delphi study.
Journal Article Eur Heart J Qual Care Clin Outcomes · December 19, 2025 AIMS: Type 2 myocardial infarction due to myocardial oxygen supply-demand imbalance is associated with poor outcomes. There are no guidelines to inform care for these patients. The consensus on the assessment and management of type 2 myocardial infarction ... Full text Link to item CiteAssociation of Maternal Prepregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood.
Journal Article Obesity (Silver Spring) · December 2025 OBJECTIVE: This study aimed to evaluate associations of maternal prepregnancy BMI with offspring BMI and blood pressure in childhood, specifically for infants born preterm. METHODS: In this observational cohort study of children in the Environmental Influe ... Full text Link to item CiteAbstract 4366483: Multi-omic Characterization of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) Trials Biorepository
Conference Circulation · November 4, 2025 Introduction/Background: CHIP is a risk factor for cardiovascular (CV) disease, cancer, and all-cause mortality. Previous work has shown that CHIP, and particularly larger CHIP clones, ... Full text CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029Preventing Myocardial Events of Aging: A PREVENTABLE Ancillary Study
ResearchCo Investigator · Awarded by Cornell University · 2024 - 2028View All Grants
Education, Training & Certifications
Indiana University at Indianapolis ·
1987
M.D.