Overview
Research Description
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
Current Appointments & Affiliations
Professor of Medicine
·
2011 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
1987 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Returning Individual-Level Urgent or Emergent Research Results to Participants: The Project Baseline Health Study Experience.
Journal Article Am J Med Open · June 2025 BACKGROUND: Returning results to research participants is increasingly recognized as an ethical mandate, yet little is known about best practices to optimally communicate urgent or emergent results. METHODS: We describe the development of and experience wi ... Full text Link to item CiteClonal Hematopoiesis of Indeterminate Potential in Chronic Coronary Disease: A Report From the ISCHEMIA Trials Biorepository.
Journal Article Circ Genom Precis Med · April 10, 2025 Full text Link to item CiteDemographic Correlates of Autism: How Do Associations Compare Between Diagnosis and a Quantitative Trait Measure?
Journal Article Autism Res · March 2025 Prevalence of autism diagnosis has historically differed by demographic factors. Using data from 8224 participants drawn from the Environmental influences on Child Health Outcomes (ECHO) Program, we examined relationships between demographic factors and pa ... Full text Link to item CiteRecent Grants
The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029Preventing Myocardial Events of Aging: A PREVENTABLE Ancillary Study
ResearchCo Investigator · Awarded by Cornell University · 2024 - 2028Mediators of Inflammation Resolution in Air Pollution's Cardio-metabolic Effects (MIRACLE)
ResearchCo-Mentor · Awarded by American Heart Association · 2025 - 2028View All Grants
Education, Training & Certifications
Indiana University at Indianapolis ·
1987
M.D.