Overview
Research Description
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
General Focus: Clinical investigation the process and treatment of acute and chronic coronary artery disease and systems issues for delivery of care to patients with these illnesses. Particular interests include management of patients with chest pain and unstable angina, evaluation of the use of biochemical markers other than CK-MB for diagnosis and risk stratification in these patients, issues related to coronary artery disease in women, and systems issues regarding optimizing the process of delivery of care to patients with acute and chronic coronary artery disease. Finally, I have a strong interest in defining the genetic contribution to development of coronary artery disease.
Key words: coronary artery disease acute myocardial infarction unstable angina chest pain women biochemical markers risk stratification genetics
Current Appointments & Affiliations
Professor of Medicine
·
2011 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
1987 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
In-Hospital Mortality Risk Among Transfers to Cardiac Intensive Care Units.
Journal Article JACC Adv · October 2025 BACKGROUND: Patients treated in tertiary cardiac intensive care units (CICUs) often arrive via transfer from other hospitals. This "transfer population" is poorly described and has been largely excluded from trials in critical care. OBJECTIVES: The aim of ... Full text Link to item CiteMedical Intensive Care Unit Overflow Into the Cardiac Intensive Care Unit: Insights From CCCTN Registry.
Journal Article JACC Adv · October 2025 BACKGROUND: Cardiac intensive care units (CICUs) typically manage critically ill patients with acute cardiovascular (CV) conditions but may serve patients with non-CV critical illness when medical ICU (MICU) beds are unavailable. OBJECTIVES: The purpose of ... Full text Link to item CiteAssociation Between Prenatal Antibiotic Exposure and Infant Wheeze Outcomes.
Journal Article Acta Paediatr · August 2025 AIM: This study examined the association between antibiotic exposure during pregnancy and the development of wheezing and cough during infancy. METHODS: We analysed data from 12 cohorts in the Environmental influences on Child Health Outcomes Cohort Consor ... Full text Link to item CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC)
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029Preventing Myocardial Events of Aging: A PREVENTABLE Ancillary Study
ResearchCo Investigator · Awarded by Cornell University · 2024 - 2028View All Grants
Education, Training & Certifications
Indiana University at Indianapolis ·
1987
M.D.