Solubility of carbon dioxide in lipid bilayer membranes and organic solvents.

Journal Article (Journal Article)

Partition coefficients of carbon dioxide into lipid bilayers (liposomes) and organic solvents were measured as a function of temperature. The molar partition coefficient of CO2 into liposomes of egg lecithin at 25 degrees C was 0.95 (ml CO2/ml lipid)/(ml CO2/ml saline). The addition of an equimolar amount of cholesterol to the egg lecithin decreased the partition coefficient by about 25%. The partition coefficients for CO2 into liposomes at 25 degrees C were lower than the partition coefficients into octanol (1.3), hexadecane (1.5) and olive oil (1.7). The results are discussed in terms of the solubility-diffusion model of non-electrolyte transport through lipid bilayer membranes.

Full Text

Duke Authors

Cited Authors

  • Simon, SA; Gutknecht, J

Published Date

  • March 13, 1980

Published In

Volume / Issue

  • 596 / 3

Start / End Page

  • 352 - 358

PubMed ID

  • 6767496

International Standard Serial Number (ISSN)

  • 0006-3002

Digital Object Identifier (DOI)

  • 10.1016/0005-2736(80)90122-4


  • eng

Conference Location

  • Netherlands