Sidney Arthur Simon | Scholars@Duke

Sidney Arthur Simon
Professor Emeritus of Neurobiology

Dr. Simon's laboratory studies the interaction of chemical stimuli with cultured and intact trigeminal ganglion neurons and taste receptor cells both in culture, in anesthetized and in awake behaving animals. We investigate how chemicals that are either bitter and/or irritating ( e.g., nicotine, capsaicin, colloidal particles) interact with particular types of receptors (e.g. nicotinic acetylcholine receptors or vanilloid receptors) to produce a bitter, irritating or painful sensation. We also investigate how these compounds evoke responses in various cortical regions such as the ventral tegmental area, orbitofrontal cortex and gustatory cortex. Our overall goal is to obtain a understanding of the events from the molecular to the behavioral levels that underlie gustatory and irritating sensations produced by chemical stimuli. We collaborate with the Nicolelis and Reinhart laboratories.

Another focus of Dr. Simon's laboratory is to investigate the physical chemical interactions that occur when peptides interact with membranes. To date we have focused on leader sequences. This work is in collaboration with the laboratory of Dr. Tom Mcintosh in the Cell Biology Department.

Current Appointments & Affiliations

Professor Emeritus of Neurobiology, Neurobiology, Basic Science Departments 2015
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2008

Contact Information

Box 3209, Durham, NC 27710
Bryan Research Building, 311 Research Drive Room 327C, Durham, NC 27710
sas@neuro.duke.edu (919) 684-4178

Background
Education, Training, & Certifications
- Ph.D., Northwestern University 1973
Previous Appointments & Affiliations
- Research Professor of Neurobiology, Neurology, Clinical Science Departments 2014
- Research Professor of Neurobiology, Neurobiology, Basic Science Departments 2009 - 2014
- Professor of Neurobiology with Tenure, Neurobiology, Basic Science Departments 1987 - 2008
- Associate Professor in Anesthesiology, Anesthesiology, Clinical Science Departments 1994 - 2008
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2003 - 2005
- Associate Professor of Physiology with tenure in the Department of Physiology, Cell Biology, Basic Science Departments 1981 - 1987
Research
Selected Grants
- Gustatory Processing and Satiety awarded by National Institutes of Health 2000 - 2012
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Novel Anesthetic Mechanisms That Desensitize Nociceptors awarded by National Institutes of Health 2002 - 2008
- Sensory Irritant Receptors and Particulate Inflammation awarded by National Institutes of Health 2000 - 2006
- Multimodal influences on cortical taste procesing awarded by National Institutes of Health 2002
- Single Cell Calcium Recordings Of Mouse Dorsal Root Gan... awarded by Environmental Protection Agency 1997 - 2000
- Chemical Responses of Oral Trigeminal Nerves awarded by National Institutes of Health 1991 - 2000
- Chemical Responses Of Oral Trigeminal Nerves awarded by National Institutes of Health 1996 - 1999
- Isothermal Titration Calorimetry for Biological Research awarded by Division of Undergraduate Education 1998 - 1999
- Short And Long-Range Forces Between Membrane Surfaces awarded by National Institutes of Health 1980 - 1999
- Short- And Long-Range Forces Between Membrane Surfaces awarded by National Institutes of Health 1993 - 1998
- Chemical Responses Of Oral Trigeminal Nerves awarded by National Institutes of Health 1993 - 1994
- Physiological Studies On Mammalian Tongue awarded by National Institutes of Health 1989 - 1991
- Functional Reconstitution Of The Olfactory Membrane awarded by Office of Naval Research 1989 - 1990
- Physiological Studies On Mammalian Tongue awarded by National Institutes of Health 1988 - 1990
- Functional Reconstitution Of The Olfactory Membrane awarded by Office of Naval Research 1987 - 1989
- Physiological Studies On Tongue awarded by National Institutes of Health 1986 - 1987
Publications & Artistic Works
Selected Publications
- Books
  - Simon, S. A. Series preface, 2016.
  - Simon, S. A. Series preface, 2016.
  - Simon, S. A. Series preface, 2016.
  - Simon, S. A. Series preface, 2015. https://doi.org/10.1201/b18126.
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  - Simon, S. A. Series preface, 2014. https://doi.org/10.1201/b16511.
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  - Simon, S. A. Series preface, 2014.
  - Simon, S. A. Series preface, 2014.
  - Simon, S. A. Series preface, 2014.
  - Simon, S. A. Series preface, 2014.
  - Simon, S. A. Series preface, 2012. https://doi.org/10.1201/b12215.
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  - Simon, S. A. Series Preface, 2012.
  - Simon, S. A., and M. A. L. Nicolelis. Series Preface, 2011.
  - Simon, S. A., and M. A. L. Nicolelis. Neurobiology of Depression, 2011.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2011.
  - Simon, S. A., and A. L. N. Miguel. Series Preface, 2010. https://doi.org/10.1201/9781420007350.
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  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2009.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2009.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2009.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2008.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2007.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2007.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2006. https://doi.org/10.1201/9781420005974.
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  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2006.
  - Simon, S. A., and M. A. L. Nicolelis. Series Preface, 2005.
  - Simon, S. A., and M. A. L. Nicolelis. Methods & new frontiers in neuroscience, 2004.
  - Simon, S. A., and M. A. L. Nicolelis. Methods & new frontiers in neuroscience, 2004.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2003.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2003.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2002.
  - Simon, S. A., and M. A. L. Nicolelis. Series preface, 2002.
  - Simon, S. A., and M. A. L. Nicolelis. Methods & new frontiers in neuroscience, 2001.
  - Simon, S. A., and M. A. L. Nicolelis. Methods & new frontiers in neuroscience, 2001.
  - Simon, S. A., and M. A. L. Nicolelis. Methods and new frontiers in neuroscience, 2000.
  - Simon, S. A., and M. A. L. Nicolelis. Series Preface, 2000.
- Academic Articles
  - Gutierrez, Ranier, and Sidney A. Simon. “Physiology of Taste Processing in the Tongue, Gut, and Brain.” Compr Physiol 11, no. 4 (September 23, 2021): 2489–2523. https://doi.org/10.1002/cphy.c210002.
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  - Gutierrez, Ranier, Esmeralda Fonseca, and Sidney A. Simon. “The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity.” Cell Mol Life Sci 77, no. 18 (September 2020): 3469–3502. https://doi.org/10.1007/s00018-020-03458-2.
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  - Fonseca, Esmeralda, Vicente Sandoval-Herrera, Sidney A. Simon, and Ranier Gutierrez. “Behavioral Disassociation of Perceived Sweet Taste Intensity and Hedonically Positive Palatability.” Eneuro 7, no. 5 (2020). https://doi.org/10.1523/ENEURO.0268-20.2020.
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  - Leijon, Sara C. M., Amanda F. Neves, Joseph M. Breza, Sidney A. Simon, Nirupa Chaudhari, and Stephen D. Roper. “Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil.” J Physiol 597, no. 7 (April 2019): 2045–61. https://doi.org/10.1113/JP277385.
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  - Fonseca, Esmeralda, Victor de Lafuente, Sidney A. Simon, and Ranier Gutierrez. “Sucrose intensity coding and decision-making in rat gustatory cortices.” Elife 7 (November 19, 2018). https://doi.org/10.7554/eLife.41152.
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  - Ortíz-Rentería, Miguel, Rebeca Juárez-Contreras, Ricardo González-Ramírez, León D. Islas, Félix Sierra-Ramírez, Itzel Llorente, Sidney A. Simon, Marcia Hiriart, Tamara Rosenbaum, and Sara L. Morales-Lázaro. “TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain.” Proc Natl Acad Sci U S A 115, no. 7 (February 13, 2018): E1657–66. https://doi.org/10.1073/pnas.1715972115.
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  - Villavicencio, Miguel, Mario G. Moreno, Sidney A. Simon, and Ranier Gutierrez. “Encoding of Sucrose's Palatability in the Nucleus Accumbens Shell and Its Modulation by Exteroceptive Auditory Cues.” Front Neurosci 12 (2018): 265. https://doi.org/10.3389/fnins.2018.00265.
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  - Prado, Luis, Jorge Luis-Islas, Osvaldo I. Sandoval, Liliana Puron, Moreno M. Gil, Alvaro Luna, Mario A. Arias-García, Elvira Galarraga, Sidney A. Simon, and Ranier Gutierrez. “Activation of Glutamatergic Fibers in the Anterior NAc Shell Modulates Reward Activity in the aNAcSh, the Lateral Hypothalamus, and Medial Prefrontal Cortex and Transiently Stops Feeding.” J Neurosci 36, no. 50 (December 14, 2016): 12511–29. https://doi.org/10.1523/JNEUROSCI.1605-16.2016.
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  - Morales-Lázaro, Sara L., Itzel Llorente, Félix Sierra-Ramírez, Ana E. López-Romero, Miguel Ortíz-Rentería, Barbara Serrano-Flores, Sidney A. Simon, León D. Islas, and Tamara Rosenbaum. “Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch.” Nat Commun 7 (October 10, 2016): 13092. https://doi.org/10.1038/ncomms13092.
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  - Hertz, L., Y. Chen, S. A. Simon, R. Gutierrez, and S. Tandon. “Editorial: All 3 types of glial cells are important for memory formation.” Frontiers in Integrative Neuroscience 10, no. SEP2016 (September 27, 2016). https://doi.org/10.3389/fnint.2016.00031.
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  - Kanju, Patrick, Yong Chen, Whasil Lee, Michele Yeo, Suk Hee Lee, Joelle Romac, Rafiq Shahid, et al. “Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.” Sci Rep 6 (June 1, 2016): 26894. https://doi.org/10.1038/srep26894.
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  - Kalyanasundar, B., Jessica Solorio, Claudia I. Perez, Carlos Hoyo-Vadillo, Sidney A. Simon, and Ranier Gutierrez. “The efficacy of the appetite suppressant, diethylpropion, is dependent on both when it is given (day vs. night) and under conditions of high fat dietary restriction.” Appetite 100 (May 1, 2016): 152–61. https://doi.org/10.1016/j.appet.2016.01.036.
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  - Gutierrez, Ranier, and Sidney A. Simon. “Why do people living in hot climates like their food spicy?” Temperature (Austin) 3, no. 1 (2016): 48–49. https://doi.org/10.1080/23328940.2015.1119616.
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  - Kalyanasundar, B., Claudia I. Perez, Alvaro Luna, Jessica Solorio, Mario G. Moreno, David Elias, Sidney A. Simon, and Ranier Gutierrez. “D1 and D2 antagonists reverse the effects of appetite suppressants on weight loss, food intake, locomotion, and rebalance spiking inhibition in the rat NAc shell.” J Neurophysiol 114, no. 1 (July 2015): 585–607. https://doi.org/10.1152/jn.00012.2015.
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  - Perez, Isaac O., Miguel Villavicencio, Sidney A. Simon, and Ranier Gutierrez. “Speed and accuracy of taste identification and palatability: impact of learning, reward expectancy, and consummatory licking.” Am J Physiol Regul Integr Comp Physiol 305, no. 3 (August 1, 2013): R252–70. https://doi.org/10.1152/ajpregu.00492.2012.
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  - Morales-Lázaro, Sara L., Sidney A. Simon, and Tamara Rosenbaum. “The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1).” J Physiol 591, no. 13 (July 1, 2013): 3109–21. https://doi.org/10.1113/jphysiol.2013.251751.
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  - Tellez, Luis A., Isaac O. Perez, Sidney A. Simon, and Ranier Gutierrez. “Transitions between sleep and feeding states in rat ventral striatum neurons.” J Neurophysiol 108, no. 6 (September 2012): 1739–51. https://doi.org/10.1152/jn.00394.2012.
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  - Tandon, Shashank, Sidney A. Simon, and Miguel A. L. Nicolelis. “Appetitive changes during salt deprivation are paralleled by widespread neuronal adaptations in nucleus accumbens, lateral hypothalamus, and central amygdala.” J Neurophysiol 108, no. 4 (August 2012): 1089–1105. https://doi.org/10.1152/jn.00236.2012.
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  - MacDonald, Christopher J., Warren H. Meck, and Sidney A. Simon. “Distinct neural ensembles in the rat gustatory cortex encode salt and water tastes.” J Physiol 590, no. 13 (July 1, 2012): 3169–84. https://doi.org/10.1113/jphysiol.2012.233486.
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  - Picazo-Juárez, Giovanni, Silvina Romero-Suárez, Andrés Nieto-Posadas, Itzel Llorente, Andrés Jara-Oseguera, Margaret Briggs, Thomas J. McIntosh, et al. “Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel.” J Biol Chem 286, no. 28 (July 15, 2011): 24966–76. https://doi.org/10.1074/jbc.M111.237537.
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  - Gutierrez, Ranier, and Sidney A. Simon. “Chemosensory processing in the taste - reward pathway.” Flavour Fragr J 26, no. 4 (July 1, 2011): 231–38. https://doi.org/10.1002/ffj.2050.
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  - Li, Jinju, Patrick Kanju, Michael Patterson, Wei-Leong Chew, Seung-Hyun Cho, Ian Gilmour, Tim Oliver, et al. “TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles.” Environ Health Perspect 119, no. 6 (June 2011): 784–93. https://doi.org/10.1289/ehp.1002807.
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  - Oliveira-Maia, A. J., C. D. Roberts, S. A. Simon, and M. A. L. Nicolelis. “Gustatory and reward brain circuits in the control of food intake.” Adv Tech Stand Neurosurg 36 (2011): 31–59. https://doi.org/10.1007/978-3-7091-0179-7_3.
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  - Oliveira-Maia, Albino J., Craig D. Roberts, Q David Walker, Brooke Luo, Cynthia Kuhn, Sidney A. Simon, and Miguel A. L. Nicolelis. “Intravascular food reward.” Plos One 6, no. 9 (2011): e24992. https://doi.org/10.1371/journal.pone.0024992.
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  - Carleton, Alan, Riccardo Accolla, and Sidney A. Simon. “Coding in the mammalian gustatory system.” Trends Neurosci 33, no. 7 (July 2010): 326–34. https://doi.org/10.1016/j.tins.2010.04.002.
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  - Kuhn, Cynthia, Misha Johnson, Alex Thomae, Brooke Luo, Sidney A. Simon, Guiying Zhou, and Q David Walker. “The emergence of gonadal hormone influences on dopaminergic function during puberty.” Horm Behav 58, no. 1 (June 2010): 122–37. https://doi.org/10.1016/j.yhbeh.2009.10.015.
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  - Gutierrez, Ranier, Sidney A. Simon, and Miguel A. L. Nicolelis. “Licking-induced synchrony in the taste-reward circuit improves cue discrimination during learning.” J Neurosci 30, no. 1 (January 6, 2010): 287–303. https://doi.org/10.1523/JNEUROSCI.0855-09.2010.
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  - Rosenbaum, Tamara, Sidney A. Simon, and Leon D. Islas. “Ion channels in analgesia research.” Methods Mol Biol 617 (2010): 223–36. https://doi.org/10.1007/978-1-60327-323-7_18.
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  - Simon, S. A. “Merging of the senses.” Frontiers in Neuroscience 2, no. AUG (December 1, 2009). https://doi.org/10.3389/neuro.01.019.2008.
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  - MacDonald, Christopher J., Warren H. Meck, Sidney A. Simon, and Miguel A. L. Nicolelis. “Taste-guided decisions differentially engage neuronal ensembles across gustatory cortices.” J Neurosci 29, no. 36 (September 9, 2009): 11271–82. https://doi.org/10.1523/JNEUROSCI.1033-09.2009.
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  - Riera, C. E., C. Menozzi-Smarrito, M. Affolter, S. Michlig, C. Munari, F. Robert, H. Vogel, S. A. Simon, and J. le Coutre. “Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.” Br J Pharmacol 157, no. 8 (August 2009): 1398–1409. https://doi.org/10.1111/j.1476-5381.2009.00307.x.
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  - Araujo, I. E. de, and S. A. Simon. “The gustatory cortex and multisensory integration.” Int J Obes (Lond) 33 Suppl 2, no. Suppl 2 (June 2009): S34–43. https://doi.org/10.1038/ijo.2009.70.
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  - Li, Jinju, Andrew J. Ghio, Seung-Hyun Cho, Constance E. Brinckerhoff, Sidney A. Simon, and Wolfgang Liedtke. “Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.” Environ Health Perspect 117, no. 3 (March 2009): 400–409. https://doi.org/10.1289/ehp.0800311.
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  - Simon, Sidney A. “Artificial Sweeteners and Metallic Taste: Role of TRP Channel.” Chemical Senses 34, no. 3 (March 1, 2009): E27–E27.
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  - Simon, Sidney A. “Synchronization of the Taste - Reward System Improves Discrimination in a Taste Guided Task.” Chemical Senses 34, no. 3 (March 1, 2009): E15–E15.
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  - Riera, Céline E., Horst Vogel, Sidney A. Simon, Sami Damak, and Johannes le Coutre. “Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels.” J Neurosci 29, no. 8 (February 25, 2009): 2654–62. https://doi.org/10.1523/JNEUROSCI.4694-08.2009.
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  - Oliveira-Maia, Albino J., Jennifer R. Stapleton-Kotloski, Vijay Lyall, Tam-Hao T. Phan, Shobha Mummalaneni, Pamela Melone, John A. Desimone, Miguel A. L. Nicolelis, and Sidney A. Simon. “Nicotine activates TRPM5-dependent and independent taste pathways.” Proc Natl Acad Sci U S A 106, no. 5 (February 3, 2009): 1596–1601. https://doi.org/10.1073/pnas.0810184106.
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  - Gutierrez, Ranier, and Sidney A. Simon. “Perinatal choline supplementation: a smart lifelong solution to age-related dementia.” Front Neurosci 2, no. 2 (December 2008): 135–36. https://doi.org/10.3389/neuro.01.040.2008.
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  - Riera, Céline E., Horst Vogel, Sidney A. Simon, Sami Damak, and Johannes le Coutre. “The capsaicin receptor participates in artificial sweetener aversion.” Biochem Biophys Res Commun 376, no. 4 (November 28, 2008): 653–57. https://doi.org/10.1016/j.bbrc.2008.09.029.
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  - Jara-Oseguera, Andrés, Sidney A. Simon, and Tamara Rosenbaum. “TRPV1: on the road to pain relief.” Curr Mol Pharmacol 1, no. 3 (November 2008): 255–69. https://doi.org/10.2174/1874467210801030255.
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  - Oliveira-Maia, Albino J., Tam-Hao T. Phan, Pamela D. Melone, Shobha Mummalaneni, Miguel A. L. Nicolelis, Sidney A. Simon, John A. DeSimone, and Vijay Lyall. “Nicotinic Acetylcholine Receptors (NACHRS): Novel Bitter Taste Receptors for Nicotine.” Chemical Senses 33, no. 8 (October 1, 2008): S113–S113.
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  - Simon, S. A., and W. Liedtke. “How irritation: The role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.” Journal of Clinical Investigation 118, no. 7 (July 1, 2008): 2383–86. https://doi.org/10.1172/JC136111.
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  - Simon, Sidney A., and Wolfgang Liedtke. “How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.” J Clin Invest 118, no. 7 (July 2008): 2383–86. https://doi.org/10.1172/JCI36111.
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  - Rawicz, W., B. A. Smith, T. J. McIntosh, S. A. Simon, and E. Evans. “Elasticity, strength, and water permeability of bilayers that contain raft microdomain-forming lipids.” Biophys J 94, no. 12 (June 2008): 4725–36. https://doi.org/10.1529/biophysj.107.121731.
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  - Araujo, I. E. de, A. J. Oliveira-Maia, T. D. Sotnikova, R. R. Gainetdinov, M. G. Caron, M. A. L. Nicolelis, and S. A. Simon. “Food Reward in the Absence of Taste Receptor Signaling (DOI:10.1016/j.neuron.2008.01.032).” Neuron 58, no. 2 (April 24, 2008): 295. https://doi.org/10.1016/j.neuron.2008.04.003.
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  - Araujo, Ivan E. de, Albino J. Oliveira-Maia, Tatyana D. Sotnikova, Raul R. Gainetdinov, Marc G. Caron, Miguel A. L. Nicolelis, and Sidney A. Simon. “Food reward in the absence of taste receptor signaling.” Neuron 57, no. 6 (March 27, 2008): 930–41. https://doi.org/10.1016/j.neuron.2008.01.032.
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  - Tong, Jihong, Lam Nguyen, Adriana Vidal, Sidney A. Simon, JH Pate Skene, and Thomas J. McIntosh. “Role of GAP-43 in sequestering phosphatidylinositol 4,5-bisphosphate to Raft bilayers.” Biophys J 94, no. 1 (January 1, 2008): 125–33. https://doi.org/10.1529/biophysj.107.110536.
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  - Soares, Ernesto S., Jennifer R. Stapleton, Abel Rodriguez, Nathan Fitzsimmons, Laura Oliveira, Miguel A. L. Nicolelis, and Sidney A. Simon. “Behavioral and neural responses to gustatory stimuli delivered non-contingently through intra-oral cannulas.” Physiol Behav 92, no. 4 (November 23, 2007): 629–42. https://doi.org/10.1016/j.physbeh.2007.05.038.
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  - Stapleton, Jennifer R., Michael L. Lavine, Miguel A. L. Nicolelis, and Sidney A. Simon. “Ensembles of gustatory cortical neurons anticipate and discriminate between tastants in a single lick.” Front Neurosci 1, no. 1 (November 2007): 161–74. https://doi.org/10.3389/neuro.01.1.1.012.2007.
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  - McIntosh, Thomas J., and Sidney A. Simon. “Bilayers as protein solvents: role of bilayer structure and elastic properties.” J Gen Physiol 130, no. 2 (August 2007): 225–27. https://doi.org/10.1085/jgp.200709841.
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  - Riera, Céline E., Horst Vogel, Sidney A. Simon, and Johannes le Coutre. “Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors.” Am J Physiol Regul Integr Comp Physiol 293, no. 2 (August 2007): R626–34. https://doi.org/10.1152/ajpregu.00286.2007.
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  - Costa, R. M., R. Gutierrez, I. E. de Araujo, M. R. P. Coelho, A. D. Kloth, R. R. Gainetdinov, M. G. Caron, M. A. L. Nicolelis, and S. A. Simon. “Dopamine levels modulate the updating of tastant values.” Genes Brain Behav 6, no. 4 (June 2007): 314–20. https://doi.org/10.1111/j.1601-183X.2006.00257.x.
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  - Liu, Lieju, Lei Chen, Wolfgang Liedtke, and S. A. Simon. “Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons.” J Neurophysiol 97, no. 3 (March 2007): 2001–15. https://doi.org/10.1152/jn.00887.2006.
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  - Araujo, I. E. de, M. A. L. Nicolelis, and S. A. Simon. “Evolution of gustation” 3 (January 1, 2007): 329–39. https://doi.org/10.1016/B0-12-370878-8/00079-3.
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  - Markin, V. S., V. G. Shlyonsky, S. A. Simon, D. J. Benos, and I. I. Ismailov. “Mechanosensitivity of gramicidin A channels in bulged bilayer membranes at constant tension.” Biophysics 51, no. 6 (December 1, 2006): 892–95. https://doi.org/10.1134/S0006350906060078.
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  - Shlyonsky, V Gh, V. S. Markin, I. Andreeva, S. E. Pedersen, S. A. Simon, D. J. Benos, and I. I. Ismailov. “Role of membrane curvature in mechanoelectrical transduction: ion carriers nonactin and valinomycin sense changes in integral bending energy.” Biochim Biophys Acta 1758, no. 11 (November 2006): 1723–31. https://doi.org/10.1016/j.bbamem.2006.09.016.
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  - Simon, Sidney A., Ivan E. de Araujo, Ranier Gutierrez, and Miguel A. L. Nicolelis. “The neural mechanisms of gustation: a distributed processing code.” Nat Rev Neurosci 7, no. 11 (November 2006): 890–901. https://doi.org/10.1038/nrn2006.
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  - Zampighi, G. A., L. M. Zampighi, N. Fain, S. Lanzavecchia, S. A. Simon, and E. M. Wright. “Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused.” Biophys J 91, no. 8 (October 15, 2006): 2910–18. https://doi.org/10.1529/biophysj.106.084814.
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  - Araujo, Ivan E. de, Ranier Gutierrez, Albino J. Oliveira-Maia, Antonio Pereira, Miguel A. L. Nicolelis, and Sidney A. Simon. “Neural ensemble coding of satiety states.” Neuron 51, no. 4 (August 17, 2006): 483–94. https://doi.org/10.1016/j.neuron.2006.07.009.
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  - Stapleton, Jennifer R., Michael L. Lavine, Robert L. Wolpert, Miguel A. L. Nicolelis, and Sidney A. Simon. “Rapid taste responses in the gustatory cortex during licking.” J Neurosci 26, no. 15 (April 12, 2006): 4126–38. https://doi.org/10.1523/JNEUROSCI.0092-06.2006.
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  - Liu, Lieju, T. M. Yang, Wolfgang Liedtke, and S. A. Simon. “Chronic IL-1beta signaling potentiates voltage-dependent sodium currents in trigeminal nociceptive neurons.” J Neurophysiol 95, no. 3 (March 2006): 1478–90. https://doi.org/10.1152/jn.00509.2005.
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  - Gutierrez, Ranier, Jose M. Carmena, Miguel A. L. Nicolelis, and S. A. Simon. “Orbitofrontal ensemble activity monitors licking and distinguishes among natural rewards.” J Neurophysiol 95, no. 1 (January 2006): 119–33. https://doi.org/10.1152/jn.00467.2005.
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  - McIntosh, Thomas J., and Sidney A. Simon. “Roles of bilayer material properties in function and distribution of membrane proteins.” Annu Rev Biophys Biomol Struct 35 (2006): 177–98. https://doi.org/10.1146/annurev.biophys.35.040405.102022.
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  - Simon, Sidney A., and Ivan E. de Araujo. “The salty and burning taste of capsaicin.” J Gen Physiol 125, no. 6 (June 2005): 531–34. https://doi.org/10.1085/jgp.200509329.
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  - Lu, G., D. Henderson, L. Liu, P. H. Reinhart, and S. A. Simon. “Erratum: TRPV1b, a functional human vanilloid receptor splice variant (Molecular Pharmacology (2004) 67 (1119-1127)).” Molecular Pharmacology 67, no. 5 (May 1, 2005): 1818. https://doi.org/10.1124/mol.67.5.
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  - Lu, Gang, Dorian Henderson, Lieju Liu, Peter H. Reinhart, and Sidney A. Simon. “TRPV1b, a functional human vanilloid receptor splice variant.” Mol Pharmacol 67, no. 4 (April 2005): 1119–27. https://doi.org/10.1124/mol.104.009852.
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  - Allende, Daniel, S. A. Simon, and Thomas J. McIntosh. “Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores.” Biophys J 88, no. 3 (March 2005): 1828–37. https://doi.org/10.1529/biophysj.104.049817.
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  - Costa, Rui M., Lieju Liu, Miguel A. L. Nicolelis, and S. A. Simon. “Gustatory effects of capsaicin that are independent of TRPV1 receptors.” Chem Senses 30 Suppl 1 (January 2005): i198–200. https://doi.org/10.1093/chemse/bjh183.
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  - Liu, Lieju, Tianming Yang, and S. A. Simon. “The protein tyrosine kinase inhibitor, genistein, decreases excitability of nociceptive neurons.” Pain 112, no. 1–2 (November 2004): 131–41. https://doi.org/10.1016/j.pain.2004.08.005.
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  - Liu, L., T. Yang, M. J. Bruno, O. S. Andersen, and S. A. Simon. “Voltage-gated ion channels in nociceptors: modulation by cGMP.” J Neurophysiol 92, no. 4 (October 2004): 2323–32. https://doi.org/10.1152/jn.00355.2004.
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  - Liedtke, Wolfgang, and S. A. Simon. “A possible role for TRPV4 receptors in asthma.” Am J Physiol Lung Cell Mol Physiol 287, no. 2 (August 2004): L269–71. https://doi.org/10.1152/ajplung.00153.2004.
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  - Liu, L., W. Zhu, Z. -. S. Zhang, T. Yang, A. Grant, G. Oxford, and S. A. Simon. “Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors.” J Neurophysiol 91, no. 4 (April 2004): 1482–91. https://doi.org/10.1152/jn.00922.2003.
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  - Agopyan, N., J. Head, S. Yu, and S. A. Simon. “TRPV1 receptors mediate particulate matter-induced apoptosis.” Am J Physiol Lung Cell Mol Physiol 286, no. 3 (March 2004): L563–72. https://doi.org/10.1152/ajplung.00299.2003.
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  - Agopyan, N., T. Bhatti, S. Yu, and S. A. Simon. “Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells.” Toxicol Appl Pharmacol 192, no. 1 (October 1, 2003): 21–35. https://doi.org/10.1016/s0041-008x(03)00259-x.
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  - McIntosh, Thomas J., Adriana Vidal, and Sidney A. Simon. “Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts.” Biophys J 85, no. 3 (September 2003): 1656–66. https://doi.org/10.1016/S0006-3495(03)74595-0.
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  - Simon, S. A., Lieju Liu, and Robert P. Erickson. “Neuropeptides modulate rat chorda tympani responses.” Am J Physiol Regul Integr Comp Physiol 284, no. 6 (June 2003): R1494–1505. https://doi.org/10.1152/ajpregu.00544.2002.
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  - Liu, L., and S. A. Simon. “Modulation of IA currents by capsaicin in rat trigeminal ganglion neurons.” J Neurophysiol 89, no. 3 (March 2003): 1387–1401. https://doi.org/10.1152/jn.00210.2002.
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  - Agopyan, N., L. Li, S. Yu, and S. A. Simon. “Negatively charged 2- and 10-microm particles activate vanilloid receptors, increase cAMP, and induce cytokine release.” Toxicol Appl Pharmacol 186, no. 2 (January 15, 2003): 63–76. https://doi.org/10.1016/s0041-008x(02)00013-3.
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  - Allende, Daniel, Adriana Vidal, Sidney A. Simon, and Thomas J. McIntosh. “Bilayer interfacial properties modulate the binding of amphipathic peptides.” Chem Phys Lipids 122, no. 1–2 (January 2003): 65–76. https://doi.org/10.1016/s0009-3084(02)00179-2.
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  - Simon, S. A. “Interactions between salt and acid stimuli: a lesson in gustation from simultaneous epithelial and neural recordings.” J Gen Physiol 120, no. 6 (December 2002): 787–91. https://doi.org/10.1085/jgp.20028735.
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  - Katz, Donald B., Miguel A. L. Nicolelis, and Sidney A. Simon. “Gustatory processing is dynamic and distributed.” Curr Opin Neurobiol 12, no. 4 (August 2002): 448–54. https://doi.org/10.1016/s0959-4388(02)00341-0.
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  - Gandhavadi, M., D. Allende, A. Vidal, S. A. Simon, and T. J. McIntosh. “Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts.” Biophys J 82, no. 3 (March 2002): 1469–82. https://doi.org/10.1016/S0006-3495(02)75501-X.
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  - Katz, Donald B., S. A. Simon, and Miguel A. L. Nicolelis. “Taste-specific neuronal ensembles in the gustatory cortex of awake rats.” J Neurosci 22, no. 5 (March 1, 2002): 1850–57. https://doi.org/10.1523/JNEUROSCI.22-05-01850.2002.
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  - McIntosh, T. J., A. Vidal, and S. A. Simon. “The energetics of peptide-lipid interactions: Modulation by interfacial dipoles and cholesterol.” Current Topics in Membranes 52 (January 1, 2002): 309–38. https://doi.org/10.1016/s1063-5823(02)52013-5.
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  - Liu, L., and S. A. Simon. “Acidic stimuli activates two distinct pathways in taste receptor cells from rat fungiform papillae.” Brain Res 923, no. 1–2 (December 27, 2001): 58–70. https://doi.org/10.1016/s0006-8993(01)03190-0.
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  - McIntosh, T. J., A. Vidal, and S. A. Simon. “The energetics of binding of a signal peptide to lipid bilayers: the role of bilayer properties.” Biochem Soc Trans 29, no. Pt 4 (August 2001): 594–98. https://doi.org/10.1042/bst0290594.
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  - Katz, D. B., S. A. Simon, and M. A. Nicolelis. “Dynamic and multimodal responses of gustatory cortical neurons in awake rats.” J Neurosci 21, no. 12 (June 15, 2001): 4478–89. https://doi.org/10.1523/JNEUROSCI.21-12-04478.2001.
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  - Liu, L., M. Oortgiesen, L. Li, and S. A. Simon. “Capsaicin inhibits activation of voltage-gated sodium currents in capsaicin-sensitive trigeminal ganglion neurons.” J Neurophysiol 85, no. 2 (February 2001): 745–58. https://doi.org/10.1152/jn.2001.85.2.745.
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  - Eichenbaum, Gary M., Patrick F. Kiser, Andrey V. Dobrynin, Sidney A. Simon, and David Needham. “Erratum: Investigation of the swelling response and loading of ionic microgels with drugs and proteins; The dependence on cross-link density (Macromolecules (July 27, 1999) 32:15 (4867-4878)).” Macromolecules 34, no. 18 (2001): 6526. https://doi.org/10.1021/ma0124892.
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  - Eichenbaum, Gary M., Patrick F. Kiser, Sidney A. Simon, and David Needham. “Erratum: pH and ion-triggered volume responses of anionic hydrogel microspheres (Macromolecules (July 28, 1998) 31:15 (5084-5093)).” Macromolecules 34, no. 20 (2001): 7230. https://doi.org/10.1021/ma012488.
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  - Welch, J. M., S. A. Simon, and P. H. Reinhart. “The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat.” Proc Natl Acad Sci U S A 97, no. 25 (December 5, 2000): 13889–94. https://doi.org/10.1073/pnas.230146497.
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  - Veronesi, B., M. Oortgiesen, J. Roy, J. D. Carter, S. A. Simon, and S. H. Gavett. “Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter.” Toxicol Appl Pharmacol 169, no. 1 (November 15, 2000): 66–76. https://doi.org/10.1006/taap.2000.9040.
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  - Eichenbaum, G. M., P. F. Kiser, D. Shah, W. P. Meuer, D. Needham, and S. A. Simon. “Alkali earth metal binding properties of ionic microgels.” Macromolecules 33, no. 11 (May 30, 2000): 4087–93. https://doi.org/10.1021/ma9917139.
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  - Liu, L., and S. A. Simon. “Capsaicin, acid and heat-evoked currents in rat trigeminal ganglion neurons: relationship to functional VR1 receptors.” Physiol Behav 69, no. 3 (May 2000): 363–78. https://doi.org/10.1016/s0031-9384(00)00209-2.
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  - Liu, L., J. M. Welch, R. P. Erickson, P. H. Reinhart, and S. A. Simon. “Different responses to repeated applications of zingerone in behavioral studies, recordings from intact and cultured TG neurons, and from VR1 receptors.” Physiol Behav 69, no. 1–2 (April 1, 2000): 177–86. https://doi.org/10.1016/s0031-9384(00)00200-6.
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  - Oortgiesen, M., B. Veronesi, G. Eichenbaum, P. F. Kiser, and S. A. Simon. “Residual oil fly ash and charged polymers activate epithelial cells and nociceptive sensory neurons.” Am J Physiol Lung Cell Mol Physiol 278, no. 4 (April 2000): L683–95. https://doi.org/10.1152/ajplung.2000.278.4.L683.
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  - Katz, D. B., M. A. Nicolelis, and S. A. Simon. “Nutrient tasting and signaling mechanisms in the gut. IV. There is more to taste than meets the tongue.” Am J Physiol Gastrointest Liver Physiol 278, no. 1 (January 2000): G6–9. https://doi.org/10.1152/ajpgi.2000.278.1.G6.
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  - Pollastri, M. P., N. A. Porter, T. J. McIntosh, and S. A. Simon. “Synthesis, structure, and thermal properties of 1,2-dipalmitoylgalloylglycerol (DPGG), a novel self-adhering lipid.” Chem Phys Lipids 104, no. 1 (January 2000): 67–74. https://doi.org/10.1016/s0009-3084(99)00110-3.
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  - Eichenbaum, G. M., P. F. Kiser, D. Shah, S. A. Simon, and D. Needham. “Investigation of the swelling response and drug loading of ionic microgels: The dependence on functional group composition.” Macromolecules 32, no. 26 (December 28, 1999): 8996–9006. https://doi.org/10.1021/ma9908393.
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  - Veronesi, B., J. D. Carter, R. B. Devlin, S. A. Simon, and M. Oortgiesen. “Neuropeptides and capsaicin stimulate the release of inflammatory cytokines in a human bronchial epithelial cell line.” Neuropeptides 33, no. 6 (December 1999): 447–56. https://doi.org/10.1054/npep.1999.0761.
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  - Katz, D. B., S. A. Simon, A. Moody, and M. A. Nicolelis. “Simultaneous reorganization in thalamocortical ensembles evolves over several hours after perioral capsaicin injections.” J Neurophysiol 82, no. 2 (August 1999): 963–77. https://doi.org/10.1152/jn.1999.82.2.963.
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  - Eichenbaum, G. M., P. F. Kiser, A. V. Dobrynin, S. A. Simon, and D. Needham. “Investigation of the swelling response and loading of ionic microgels with drugs and proteins: the dependence on cross-link density.” Macromolecules 32, no. 15 (July 27, 1999): 4867–78. https://doi.org/10.1021/ma981945s.
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  - Voglino, L., S. A. Simon, and T. J. McIntosh. “Orientation of LamB signal peptides in bilayers: influence of lipid probes on peptide binding and interpretation of fluorescence quenching data.” Biochemistry 38, no. 23 (June 8, 1999): 7509–16. https://doi.org/10.1021/bi990099q.
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  - McIntosh, T. J., K. G. Kulkarni, and S. A. Simon. “Membrane fusion promoters and inhibitors have contrasting effects on lipid bilayer structure and undulations.” Biophys J 76, no. 4 (April 1999): 2090–98. https://doi.org/10.1016/S0006-3495(99)77365-0.
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  - McIntosh, T. J., M. P. Pollastri, N. A. Porter, and S. A. Simon. “Polyphenols increase adhesion between lipid bilayers by forming interbilayer bridges.” Basic Life Sci 66 (1999): 451–70. https://doi.org/10.1007/978-1-4615-4139-4_24.
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  - Liu, L., G. Q. Chang, Y. Q. Jiao, and S. A. Simon. “Neuronal nicotinic acetylcholine receptors in rat trigeminal ganglia.” Brain Res 809, no. 2 (November 2, 1998): 238–45. https://doi.org/10.1016/s0006-8993(98)00862-2.
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  - Liu, L., and S. A. Simon. “The influence of removing extracellular Ca2+ in the desensitization responses to capsaicin, zingerone and olvanil in rat trigeminal ganglion neurons.” Brain Res 809, no. 2 (November 2, 1998): 246–52. https://doi.org/10.1016/s0006-8993(98)00853-1.
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  - Voglino, L., T. J. McIntosh, and S. A. Simon. “Modulation of the binding of signal peptides to lipid bilayers by dipoles near the hydrocarbon-water interface.” Biochemistry 37, no. 35 (September 1, 1998): 12241–52. https://doi.org/10.1021/bi9805792.
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  - Eichenbaum, G. M., P. F. Kiser, S. A. Simon, and D. Needham. “pH and Ion-Triggered Volume Response of Anionic Hydrogel Microspheres.” Macromolecules 31, no. 15 (July 28, 1998): 5084–93. https://doi.org/10.1021/ma970897t.
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  - Liu, L., A. Szallasi, and S. A. Simon. “A non-pungent resiniferatoxin analogue, phorbol 12-phenylacetate 13 acetate 20-homovanillate, reveals vanilloid receptor subtypes on rat trigeminal ganglion neurons.” Neuroscience 84, no. 2 (May 1998): 569–81. https://doi.org/10.1016/s0306-4522(97)00523-x.
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  - Liu, L., and S. A. Simon. “Responses of cultured rat trigeminal ganglion neurons to bitter tastants.” Chem Senses 23, no. 2 (April 1998): 125–30. https://doi.org/10.1093/chemse/23.2.125.
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  - Needham, D., T. J. McIntosh, S. A. Simon, and D. Zhelev. “Adsorption, molecular exchange and defect formation in membranes.” Current Opinion in Colloid and Interface Science 3, no. 5 (January 1, 1998): 511–17. https://doi.org/10.1016/S1359-0294(98)80026-5.
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  - Liu, L., Y. Lo, I. Chen, and S. A. Simon. “The responses of rat trigeminal ganglion neurons to capsaicin and two nonpungent vanilloid receptor agonists, olvanil and glyceryl nonamide.” J Neurosci 17, no. 11 (June 1, 1997): 4101–11. https://doi.org/10.1523/JNEUROSCI.17-11-04101.1997.
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  - Liu, L., and S. A. Simon. “Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia.” Neurosci Lett 228, no. 1 (May 30, 1997): 29–32. https://doi.org/10.1016/s0304-3940(97)00358-3.
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  - Dahl, M., R. P. Erickson, and S. A. Simon. “Neural responses to bitter compounds in rats.” Brain Res 756, no. 1–2 (May 9, 1997): 22–34. https://doi.org/10.1016/s0006-8993(97)00131-5.
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  - McIntosh, T. J., and S. A. Simon. “Experimental tests for thermally-induced fluctuations in lipid bilayers.” Progress in Colloid and Polymer Science 103 (January 1, 1997): 95–106. https://doi.org/10.1007/3-798-51084-9_11.
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  - Menco, B. P. M., M. P. Yankova, and S. A. Simon. “Freeze-substitution and postembedding immunocytochemistry on rat taste buds: G-proteins, calcitonin gene-related peptide, and choline acetyl transferase.” Microscopy and Microanalysis 3, no. 1 (January 1, 1997): 53–69. https://doi.org/10.1017/s1431927697970045.
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  - Huh, N. W., N. A. Porter, T. J. McIntosh, and S. A. Simon. “The interaction of polyphenols with bilayers: conditions for increasing bilayer adhesion.” Biophys J 71, no. 6 (December 1996): 3261–77. https://doi.org/10.1016/S0006-3495(96)79519-X.
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  - McIntosh, T. J., S. A. Simon, P. Vierling, C. Santaella, and V. Ravily. “Structure and interactive properties of highly fluorinated phospholipid bilayers.” Biophys J 71, no. 4 (October 1996): 1853–68. https://doi.org/10.1016/S0006-3495(96)79385-2.
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  - McIntosh, T. J., and S. A. Simon. “Short-range pressures between lipid bilayer membranes.” Colloids and Surfaces A: Physicochemical and Engineering Aspects 116, no. 3 (September 30, 1996): 251–68. https://doi.org/10.1016/0927-7757(96)03569-8.
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  - Liu, L., and S. A. Simon. “Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells.” J Neurophysiol 76, no. 3 (September 1996): 1858–69. https://doi.org/10.1152/jn.1996.76.3.1858.
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  - Chang, G. Q., S. R. Vigna, and S. A. Simon. “Localization of substance P NK-1 receptors in rat tongue.” Regul Pept 63, no. 2–3 (July 5, 1996): 85–89. https://doi.org/10.1016/0167-0115(96)00021-3.
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  - Liu, L., and S. A. Simon. “Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons.” Am J Physiol 270, no. 6 Pt 1 (June 1996): C1807–14. https://doi.org/10.1152/ajpcell.1996.270.6.C1807.
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  - Liu, L., and S. A. Simon. “Capsaicin-induced currents with distinct desensitization and Ca2+ dependence in rat trigeminal ganglion cells.” J Neurophysiol 75, no. 4 (April 1996): 1503–14. https://doi.org/10.1152/jn.1996.75.4.1503.
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  - McIntosh, T. J., and S. A. Simon. “Adhesion between phosphatidylethanolamine bilayers.” Langmuir 12, no. 6 (March 20, 1996): 1622–30. https://doi.org/10.1021/la950833g.
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  - Liu, L., Y. Wang, and S. A. Simon. “Capsaicin activated currents in rat dorsal root ganglion cells.” Pain 64, no. 1 (January 1996): 191–95. https://doi.org/10.1016/0304-3959(94)00097-2.
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  - Simon, S. A., S. Advani, and T. J. McIntosh. “Temperature dependence of the repulsive pressure between phosphatidylcholine bilayers.” Biophys J 69, no. 4 (October 1995): 1473–83. https://doi.org/10.1016/S0006-3495(95)80017-2.
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  - McIntosh, T. J., S. Advani, R. E. Burton, D. V. Zhelev, D. Needham, and S. A. Simon. “Experimental tests for protrusion and undulation pressures in phospholipid bilayers.” Biochemistry 34, no. 27 (July 11, 1995): 8520–32. https://doi.org/10.1021/bi00027a002.
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  - Margolis, L., B. Baibakov, C. Collin, and S. A. Simon. “Dye-coupling in three-dimensional histoculture of rat lingual frenulum.” In Vitro Cell Dev Biol Anim 31, no. 6 (June 1995): 456–61. https://doi.org/10.1007/BF02634258.
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  - Kenworthy, A. K., S. A. Simon, and T. J. McIntosh. “Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol).” Biophys J 68, no. 5 (May 1995): 1903–20. https://doi.org/10.1016/S0006-3495(95)80368-1.
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  - Wang, Y., R. P. Erickson, and S. A. Simon. “Modulation of rat chorda tympani nerve activity by lingual nerve stimulation.” J Neurophysiol 73, no. 4 (April 1995): 1468–83. https://doi.org/10.1152/jn.1995.73.4.1468.
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  - Simon, S. A., and T. J. McIntosh. “Role of water in short-range repulsive and attractive interactions between macromolecules and bilayers.” Cold Spring Harb Symp Quant Biol 60 (1995): 601–8. https://doi.org/10.1101/sqb.1995.060.01.064.
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  - McIntosh, T. J., and S. A. Simon. “Long- and short-range interactions between phospholipid/ganglioside GM1 bilayers.” Biochemistry 33, no. 34 (August 30, 1994): 10477–86. https://doi.org/10.1021/bi00200a032.
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  - Simon, S. A., E. A. Disalvo, K. Gawrisch, V. Borovyagin, E. Toone, S. S. Schiffman, D. Needham, and T. J. McIntosh. “Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid.” Biophys J 66, no. 6 (June 1994): 1943–58. https://doi.org/10.1016/S0006-3495(94)80988-9.
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  - Liu, L., and S. A. Simon. “A rapid capsaicin-activated current in rat trigeminal ganglion neurons.” Proc Natl Acad Sci U S A 91, no. 2 (January 18, 1994): 738–41. https://doi.org/10.1073/pnas.91.2.738.
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  - McIntosh, T. J., and S. A. Simon. “Hydration and steric pressures between phospholipid bilayers.” Annu Rev Biophys Biomol Struct 23 (1994): 27–51. https://doi.org/10.1146/annurev.bb.23.060194.000331.
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  - Simon, S. A., V. F. Holland, D. J. Benos, and G. A. Zampighi. “Transcellular and paracellular pathways in lingual epithelia and their influence in taste transduction.” Microsc Res Tech 26, no. 3 (October 15, 1993): 196–208. https://doi.org/10.1002/jemt.1070260303.
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  - McIntosh, T. J., and S. A. Simon. “Contributions of hydration and steric (entropic) pressures to the interactions between phosphatidylcholine bilayers: experiments with the subgel phase.” Biochemistry 32, no. 32 (August 17, 1993): 8374–84. https://doi.org/10.1021/bi00083a042.
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  - Liu, L., W. Pugh, H. Ma, and S. A. Simon. “Identification of acetylcholine receptors in adult rat trigeminal ganglion neurons.” Brain Res 617, no. 1 (July 16, 1993): 37–42. https://doi.org/10.1016/0006-8993(93)90609-q.
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  - Simon, S. A., E. J. Elliott, R. P. Erickson, and V. F. Holland. “Ion transport across lingual epithelium is modulated by chorda tympani nerve fibers.” Brain Res 615, no. 2 (July 2, 1993): 218–28. https://doi.org/10.1016/0006-8993(93)90031-h.
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  - Wang, Y., R. P. Erickson, and S. A. Simon. “Selectivity of lingual nerve fibers to chemical stimuli.” J Gen Physiol 101, no. 6 (June 1993): 843–66. https://doi.org/10.1085/jgp.101.6.843.
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  - Simon, S. A. “An enthalpic model of anesthesia.” Biophys J 64, no. 4 (April 1993): 1272. https://doi.org/10.1016/S0006-3495(93)81460-7.
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  - Schiffman, S. S., M. S. Suggs, and S. A. Simon. “Astringent compounds suppress taste responses in gerbil.” Brain Res 595, no. 1 (November 6, 1992): 1–11. https://doi.org/10.1016/0006-8993(92)91445-k.
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  - Simon, S. A. “Influence of tight junctions on the interaction of salts with lingual epithelia: responses of chorda tympani and lingual nerves.” Mol Cell Biochem 114, no. 1–2 (September 8, 1992): 43–48. https://doi.org/10.1007/BF00240296.
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  - Simon, S. A., W. L. Hall, and S. S. Schiffman. “Astringent-tasting compounds alter ion transport across isolated canine lingual epithelia.” Pharmacol Biochem Behav 43, no. 1 (September 1992): 271–83. https://doi.org/10.1016/0091-3057(92)90668-6.
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  - Simon, S. A., and H. C. Baggett. “Identification of muscarinic acetylcholine receptors in isolated canine lingual epithelia via voltage clamp measurements.” Arch Oral Biol 37, no. 9 (September 1992): 685–90. https://doi.org/10.1016/0003-9969(92)90072-g.
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  - Simon, S. A., T. J. McIntosh, A. D. Magid, and D. Needham. “Modulation of the interbilayer hydration pressure by the addition of dipoles at the hydrocarbon/water interface.” Biophys J 61, no. 3 (March 1992): 786–99. https://doi.org/10.1016/S0006-3495(92)81883-0.
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  - McIntosh, T. J., S. A. Simon, D. Needham, and C. H. Huang. “Structure and cohesive properties of sphingomyelin/cholesterol bilayers.” Biochemistry 31, no. 7 (February 25, 1992): 2012–20. https://doi.org/10.1021/bi00122a017.
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  - McIntosh, T. J., S. A. Simon, D. Needham, and C. H. Huang. “Interbilayer interactions between sphingomyelin and sphingomyelin/cholesterol bilayers.” Biochemistry 31, no. 7 (February 25, 1992): 2020–24. https://doi.org/10.1021/bi00122a018.
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  - Ceckler, T. L., S. D. Wolff, V. Yip, S. A. Simon, and R. S. Balaban. “Dynamic and chemical factors affecting water proton relaxation by macromolecules.” Journal of Magnetic Resonance (1969) 98, no. 3 (January 1, 1992): 637–45. https://doi.org/10.1016/0022-2364(92)90018-3.
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  - Schiffman, S. S., M. S. Suggs, A. L. Sostman, and S. A. Simon. “Chorda tympani and lingual nerve responses to astringent compounds in rodents.” Physiol Behav 51, no. 1 (January 1992): 55–63. https://doi.org/10.1016/0031-9384(92)90203-e.
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  - Zampighi, G. A., S. A. Simon, and J. E. Hall. “The specialized junctions of the lens.” Int Rev Cytol 136 (1992): 185–225. https://doi.org/10.1016/s0074-7696(08)62053-7.
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  - Simon, S. A., V. F. Holland, and G. Zampighi. “Localization of Na,K-atpase in lingual epithelia.” Chemical Senses 16, no. 3 (June 1, 1991): 283–93. https://doi.org/10.1093/chemse/16.3.283.
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  - Simon, S. A., and T. J. McIntosh. “Surface ripples cause the large fluid spaces between gel phase bilayers containing small amounts of cholesterol.” Biochim Biophys Acta 1064, no. 1 (April 26, 1991): 69–74. https://doi.org/10.1016/0005-2736(91)90412-2.
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  - Fralix, T. A., T. L. Ceckler, S. D. Wolff, S. A. Simon, and R. S. Balaban. “Lipid bilayer and water proton magnetization transfer: effect of cholesterol.” Magn Reson Med 18, no. 1 (March 1991): 214–23. https://doi.org/10.1002/mrm.1910180122.
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  - Simon, S. A., C. A. Fink, A. K. Kenworthy, and T. J. McIntosh. “The hydration pressure between lipid bilayers. Comparison of measurements using x-ray diffraction and calorimetry.” Biophys J 59, no. 3 (March 1991): 538–46. https://doi.org/10.1016/S0006-3495(91)82270-6.
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  - Holland, V. F., G. A. Zampighi, and S. A. Simon. “Tight junctions in taste buds: Possible role in perception of intravascular gustatory stimuli.” Chemical Senses 16, no. 1 (February 1, 1991): 69–79. https://doi.org/10.1093/chemse/16.1.69.
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  - Simon, S. A., and A. L. Sostman. “Electrophysiological responses to non-electrolytes in lingual nerve of rat and in lingual epithelia of dog.” Arch Oral Biol 36, no. 11 (1991): 805–13. https://doi.org/10.1016/0003-9969(91)90030-x.
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  - Sostman, A. L., and S. A. Simon. “Trigeminal nerve responses in the rat elicited by chemical stimulation of the tongue.” Arch Oral Biol 36, no. 2 (1991): 95–102. https://doi.org/10.1016/0003-9969(91)90071-2.
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  - Elliott, E. J., and S. A. Simon. “The anion in salt taste: a possible role for paracellular pathways.” Brain Res 535, no. 1 (December 3, 1990): 9–17. https://doi.org/10.1016/0006-8993(90)91817-z.
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  - McIntosh, T. J., A. D. Magid, and S. A. Simon. “Interactions between charged, uncharged, and zwitterionic bilayers containing phosphatidylglycerol.” Biophys J 57, no. 6 (June 1990): 1187–97. https://doi.org/10.1016/S0006-3495(90)82638-2.
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  - Simon, S. A., and J. Verbrugge. “Transport pathways in canine lingual epithelium involved in sweet taste.” Chemical Senses 15, no. 1 (February 1, 1990): 1–25. https://doi.org/10.1093/chemse/15.1.1.
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  - Simon, S. A., and T. J. McIntosh. “Magnitude of the solvation pressure depends on dipole potential.” Proc Natl Acad Sci U S A 86, no. 23 (December 1989): 9263–67. https://doi.org/10.1073/pnas.86.23.9263.
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  - McIntosh, T. J., A. D. Magid, and S. A. Simon. “Range of the solvation pressure between lipid membranes: dependence on the packing density of solvent molecules.” Biochemistry 28, no. 19 (September 19, 1989): 7904–12. https://doi.org/10.1021/bi00445a053.
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  - Zampighi, G. A., J. E. Hall, G. R. Ehring, and S. A. Simon. “The structural organization and protein composition of lens fiber junctions.” J Cell Biol 108, no. 6 (June 1989): 2255–75. https://doi.org/10.1083/jcb.108.6.2255.
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  - McIntosh, T. J., A. D. Magid, and S. A. Simon. “Repulsive interactions between uncharged bilayers. Hydration and fluctuation pressures for monoglycerides.” Biophys J 55, no. 5 (May 1989): 897–904. https://doi.org/10.1016/S0006-3495(89)82888-7.
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  - Simon, S. A., P. Labarca, and R. Robb. “Activation by saccharides of a cation-selective pathway on canine lingual epithelium.” Am J Physiol 256, no. 2 Pt 2 (February 1989): R394–402. https://doi.org/10.1152/ajpregu.1989.256.2.R394.
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  - McIntosh, T. J., A. D. Magid, and S. A. Simon. “Cholesterol modifies the short-range repulsive interactions between phosphatidylcholine membranes.” Biochemistry 28, no. 1 (January 10, 1989): 17–25. https://doi.org/10.1021/bi00427a004.
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  - Holland, V. F., G. A. Zampighi, and S. A. Simon. “Morphology of fungiform papillae in canine lingual epithelium: location of intercellular junctions in the epithelium.” J Comp Neurol 279, no. 1 (January 1, 1989): 13–27. https://doi.org/10.1002/cne.902790103.
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  - Rivera, A., F. Ramon, S. A. Simon, and G. A. Zampighi. “How many channels should there be in a gap junction?” P R Health Sci J 7, no. 2 (August 1988): 133–40.
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  - Garvin, J. L., R. Robb, and S. A. Simon. “Spatial map of salts and saccharides on dog tongue.” Am J Physiol 255, no. 1 Pt 2 (July 1988): R117–22. https://doi.org/10.1152/ajpregu.1988.255.1.R117.
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  - Zampighi, G., M. Kreman, F. Ramón, A. L. Moreno, and S. A. Simon. “Structural characteristics of gap junctions. I. Channel number in coupled and uncoupled conditions.” J Cell Biol 106, no. 5 (May 1988): 1667–78. https://doi.org/10.1083/jcb.106.5.1667.
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  - Labarca, P., S. A. Simon, and R. R. Anholt. “Activation by odorants of a multistate cation channel from olfactory cilia.” Proc Natl Acad Sci U S A 85, no. 3 (February 1988): 944–47. https://doi.org/10.1073/pnas.85.3.944.
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  - Simon, S. A., R. Robb, and S. S. Schiffman. “Transport pathways in rat lingual epithelium.” Pharmacol Biochem Behav 29, no. 2 (February 1988): 257–67. https://doi.org/10.1016/0091-3057(88)90154-2.
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  - Simon, S. A., T. J. McIntosh, and A. D. Magid. “Magnitude and range of the hydration pressure between lecithin bilayers as a function of headgroup density.” Journal of Colloid and Interface Science 126, no. 1 (January 1, 1988): 74–83. https://doi.org/10.1016/0021-9797(88)90101-4.
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  - McIntosh, T. J., A. D. Magid, and S. A. Simon. “Steric repulsion between phosphatidylcholine bilayers.” Biochemistry 26, no. 23 (November 17, 1987): 7325–32. https://doi.org/10.1021/bi00397a020.
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  - MacDonald, R. C., and S. A. Simon. “Lipid monolayer states and their relationships to bilayers.” Proc Natl Acad Sci U S A 84, no. 12 (June 1987): 4089–93. https://doi.org/10.1073/pnas.84.12.4089.
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  - SCHIFFMAN, S. S., S. A. SIMON, J. M. GILL, and T. G. BEEKER. “Bretylium Tosylate Enhances Salt Taste via Amiloride‐Sensitive Pathway.” Annals of the New York Academy of Sciences 510, no. 1 (January 1, 1987): 584–86. https://doi.org/10.1111/j.1749-6632.1987.tb43632.x.
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  - SIMON, S. A., R. ROBB, and J. L. GARVIN. “Differences in Epithelial Responses of Rabbit Tongue to KCl and NaCl.” Annals of the New York Academy of Sciences 510, no. 1 (January 1, 1987): 619–22. https://doi.org/10.1111/j.1749-6632.1987.tb43645.x.
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  - McIntosh, T. J., and S. A. Simon. “Erratum: Area per molecule and distribution of water in fully hydrated dilauroylphosphatidylethanolamine bilayers (Biochemistry (1986) 25:17 (4948-4952)).” Biochemistry 25, no. 26 (December 1, 1986): 8474.
  - Simon, S. A., R. Robb, and J. L. Garvin. “Epithelial responses of rabbit tongues and their involvement in taste transduction.” Am J Physiol 251, no. 3 Pt 2 (September 1986): R598–608. https://doi.org/10.1152/ajpregu.1986.251.3.R598.
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  - McIntosh, T. J., and S. A. Simon. “Area per molecule and distribution of water in fully hydrated dilauroylphosphatidylethanolamine bilayers.” Biochemistry 25, no. 17 (August 26, 1986): 4948–52. https://doi.org/10.1021/bi00365a034.
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  - McIntosh, T. J., and S. A. Simon. “Hydration force and bilayer deformation: a reevaluation.” Biochemistry 25, no. 14 (July 15, 1986): 4058–66. https://doi.org/10.1021/bi00362a011.
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  - De Datta, S. K., and W. H. Patrick. “Preface.” Fertilizer Research 9, no. 1–2 (February 1, 1986). https://doi.org/10.1007/BF01048692.
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  - Zampighi, G., S. A. Simon, J. Kyte, and M. Kreman. “One-dimensional crystals of (Na+ + K+)-ATPase dimers.” Biochim Biophys Acta 854, no. 1 (January 16, 1986): 45–57. https://doi.org/10.1016/0005-2736(86)90063-5.
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  - Garvin, J. L., S. A. Simon, E. J. Cragoe, and L. J. Mandel. “Binding of 3H-phenamil, an irreversible amiloride analog, to toad urinary bladder: effects of aldosterone and vasopressin.” J Membr Biol 90, no. 2 (1986): 107–13. https://doi.org/10.1007/BF01869928.
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  - Schiffman, S. S., S. A. Simon, J. M. Gill, and T. G. Beeker. “Bretylium tosylate enhances salt taste.” Physiol Behav 36, no. 6 (1986): 1129–37. https://doi.org/10.1016/0031-9384(86)90490-7.
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  - Simon, S. A., and T. J. McIntosh. “Depth of water penetration into lipid bilayers.” Methods Enzymol 127 (1986): 511–21. https://doi.org/10.1016/0076-6879(86)27041-x.
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  - Zampighi, G., S. A. Simon, J. Kyte, and M. Kreman. “One-dimensional crystals of (Na⁺ + K⁺)-ATPase dimers.” Bba Biomembranes 854, no. 1 (1986): 45–57.
  - Simon, S. A., and J. L. Garvin. “Salt and acid studies on canine lingual epithelium.” American Journal of Physiology Cell Physiology 18, no. 3 (December 1, 1985).
  - Simon, S. A., and J. L. Garvin. “Salt and acid studies on canine lingual epithelium.” Am J Physiol 249, no. 5 Pt 1 (November 1985): C398–408. https://doi.org/10.1152/ajpcell.1985.249.5.C398.
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  - Garvin, J. L., S. A. Simon, E. J. Cragoe, and L. J. Mandel. “Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder.” J Membr Biol 87, no. 1 (1985): 45–54. https://doi.org/10.1007/BF01870698.
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  - Vergara, J. L., M. E. Kreman, G. A. Zamighi, and S. A. Simon. “An atomizer for a dime.” Journal of Chemical Education 62, no. 3 (January 1, 1985): 244. https://doi.org/10.1021/ed062p244.
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  - McIntosh, T. J., S. A. Simon, J. C. Ellington, and N. A. Porter. “New structural model for mixed-chain phosphatidylcholine bilayers.” Biochemistry 23, no. 18 (August 28, 1984): 4038–44. https://doi.org/10.1021/bi00313a005.
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  - Simon, S. A., and T. J. McIntosh. “Interdigitated hydrocarbon chain packing causes the biphasic transition behavior in lipid/alcohol suspensions.” Biochim Biophys Acta 773, no. 1 (June 13, 1984): 169–72. https://doi.org/10.1016/0005-2736(84)90562-5.
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  - McDaniel, R. V., T. J. McIntosh, and S. A. Simon. “Nonelectrolyte substitution for water in phosphatidylcholine bilayers.” Bba Biomembranes 731, no. 1 (May 26, 1983): 97–108. https://doi.org/10.1016/0005-2736(83)90402-9.
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  - McIntosh, T. J., R. V. McDaniel, and S. A. Simon. “Induction of an interdigitated gel phase in fully hydrated phosphatidylcholine bilayers.” Bba Biomembranes 731, no. 1 (May 26, 1983): 109–14. https://doi.org/10.1016/0005-2736(83)90403-0.
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  - Simon, S. A., J. L. Parmentier, and P. B. Bennett. “Anesthetic antagonism of the effects of high hydrostatic pressure on locomotory activity of the brine shrimp Artemia.” Comp Biochem Physiol a Comp Physiol 75, no. 2 (1983): 193–99. https://doi.org/10.1016/0300-9629(83)90069-5.
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  - McDaniel, R. V., S. A. Simon, T. J. McIntosh, and V. Borovyagin. “Interaction of benzene with bilayers. Thermal and structural studies.” Biochemistry 21, no. 17 (August 17, 1982): 4116–26. https://doi.org/10.1021/bi00260a031.
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  - Simon, S. A., G. Zampighi, T. J. McIntosh, M. J. Costello, H. P. Ting-beall, and J. D. Robertson. “The structure of junctions between lens fiber cells.” Biosci Rep 2, no. 5 (May 1982): 333–41. https://doi.org/10.1007/BF01115119.
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  - Simon, S. A., T. J. McIntosh, and R. Latorre. “Influence of cholesterol on water penetration into bilayers.” Science 216, no. 4541 (April 2, 1982): 65–67. https://doi.org/10.1126/science.7063872.
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  - Zampighi, G., S. A. Simon, J. D. Robertson, T. J. McIntosh, and M. J. Costello. “On the structural organization of isolated bovine lens fiber junctions.” J Cell Biol 93, no. 1 (April 1982): 175–89. https://doi.org/10.1083/jcb.93.1.175.
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  - McDaniel, R. V., S. A. Simon, T. J. McIntosh, and V. Borovyagin. “The interaction of benzene with lecithin bilayers.” Biophysical Journal 37, no. 2 II (January 1, 1982).
  - Simon, S. A., R. V. McDaniel, and T. J. McIntosh. “Interaction of benzene with micelles and bilayers.” Journal of Physical Chemistry 86, no. 8 (January 1, 1982): 1449–56. https://doi.org/10.1021/j100397a048.
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  - Simon, S. A., Czysz M. F. III, K. Everett, and C. Field. “Polytropic, differentially rotating cylinders.” Am. J. Phys. (Usa) 49, no. 7 (1981): 662–65.
  - Simon, S. A., and D. Hurley. “Simplified models of completely degenerate, differentially rotating stars.” Am. J. Phys. (Usa) 49, no. 1 (1981): 20–24.
  - Benos, D. J., L. J. Mandel, and S. A. Simon. “Effects of chemical group specific reagents on sodium entry and the amiloride binding site in frog skin: evidence for separate sites.” J Membr Biol 56, no. 2 (September 30, 1980): 149–58. https://doi.org/10.1007/BF01875966.
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  - Benos, D. J., L. J. Mandel, and S. A. Simon. “Cationic selectivity and competition at the sodium entry site in frog skin.” J Gen Physiol 76, no. 2 (August 1980): 233–47. https://doi.org/10.1085/jgp.76.2.233.
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  - Johnston, M. F., S. A. Simon, and F. Ramón. “Interaction of anaesthetics with electrical synapses.” Nature 286, no. 5772 (July 31, 1980): 498–500. https://doi.org/10.1038/286498a0.
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  - McIntosh, T. J., S. A. Simon, and R. C. MacDonald. “The organization of n-alkanes in lipid bilayers.” Biochim Biophys Acta 597, no. 3 (April 24, 1980): 445–63. https://doi.org/10.1016/0005-2736(80)90219-9.
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  - Simon, S. A., and J. Gutknecht. “Solubility of carbon dioxide in lipid bilayer membranes and organic solvents.” Biochim Biophys Acta 596, no. 3 (March 13, 1980): 352–58. https://doi.org/10.1016/0005-2736(80)90122-4.
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  - Dilger, J. P., S. G. McLaughlin, T. J. McIntosh, and S. A. Simon. “The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.” Science 206, no. 4423 (December 7, 1979): 1196–98. https://doi.org/10.1126/science.228394.
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  - Ebihara, L., J. E. Hall, R. C. MacDonald, T. J. McIntosh, and S. A. Simon. “Effect of benzyl alcohol on lipid bilayers. A comparisons of bilayer systems.” Biophys J 28, no. 2 (November 1979): 185–96. https://doi.org/10.1016/S0006-3495(79)85170-X.
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  - Simon, S. A., T. J. McIntosh, P. B. Bennett, and B. B. Shrivastav. “Interaction of halothane with lipid bilayers.” Mol Pharmacol 16, no. 1 (July 1979): 163–70.
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  - Simon, S. A., W. L. Stone, and P. B. Bennett. “Can regular solution theory be applied to lipid bilayer membranes?” Biochim Biophys Acta 550, no. 1 (January 5, 1979): 38–47. https://doi.org/10.1016/0005-2736(79)90113-5.
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  - Simon, S. A. “A numerical technique for the solution of Poisson's equation for flattened, centrally condensed objects.” Astrophys. J. (Usa) 228, no. 1 (1979): 357–63. https://doi.org/10.1086/156853.
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  - Katz, Y., and S. A. Simon. “A physical theory of general anesthesia.” Biophysical Journal 17, no. 2 (December 1, 1977).
  - Katz, Y., and S. A. Simon. “Physical parameters of the anesthetic site.” Biochim Biophys Acta 471, no. 1 (November 15, 1977): 1–15. https://doi.org/10.1016/0005-2736(77)90387-x.
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  - Simon, S. A., W. L. Stone, and P. Busto-Latorre. “A thermodynamic study of the partition of n-hexane into phosphatidylcholine and phosphatidylcholine-cholesterol bilayers.” Biochim Biophys Acta 468, no. 3 (August 1, 1977): 378–88. https://doi.org/10.1016/0005-2736(77)90289-9.
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  - Simon, S. A. “A comment on the water permeability through planar lipid bilayers.” J Gen Physiol 70, no. 1 (July 1977): 123–27. https://doi.org/10.1085/jgp.70.1.123.
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  - Simon, S. A., L. J. Lis, R. C. MacDonald, and J. W. Kauffman. “The noneffect of a large linear hydrocarbon, squalene, on the phosphatidylcholine packing structure.” Biophys J 19, no. 1 (July 1977): 83–90. https://doi.org/10.1016/S0006-3495(77)85570-7.
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  - Benos, D. J., S. A. Simon, L. J. Mandel, and P. M. Cala. “Effect of amiloride and some of its analogues of cation transport in isolated frog skin and thin lipid membranes.” J Gen Physiol 68, no. 1 (July 1976): 43–63. https://doi.org/10.1085/jgp.68.1.43.
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  - Hall, J. E., and S. A. Simon. “A simple model for calcium induced exocytosis.” Biochim Biophys Acta 436, no. 3 (July 1, 1976): 613–16. https://doi.org/10.1016/0005-2736(76)90444-2.
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  - White, S. H., D. C. Petersen, S. Simon, and M. Yafuso. “Formation of planar bilayer membranes from lipid monolayers. A critique.” Biophys J 16, no. 5 (May 1976): 481–89. https://doi.org/10.1016/S0006-3495(76)85703-7.
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  - MacDonald, R. C., S. A. Simon, and E. Baer. “Ionic influences on the phase transition of dipalmitoylphosphatidylserine.” Biochemistry 15, no. 4 (February 24, 1976): 885–91. https://doi.org/10.1021/bi00649a025.
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  - Simon, S. A., R. C. MacDonald, and P. B. Bennett. “Phase changes induced by cyclopropane of phosphatidylserine bilayers in the presence and absence of calcium.” Biochem Biophys Res Commun 67, no. 3 (December 1, 1975): 988–94. https://doi.org/10.1016/0006-291x(75)90772-x.
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  - Simon, S., Y. Katz, and P. B. Bennett. “Calculation of the percentage of a narcotic gas to permit abolition of the high pressure nervous syndrome.” Undersea Biomed Res 2, no. 4 (December 1975): 299–303.
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  - Evans, E. A., and S. Simon. “Mechanics of electrocompression of lipid bilayer membranes.” Biophys J 15, no. 8 (August 1975): 850–52. https://doi.org/10.1016/S0006-3495(75)85860-7.
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  - Simon, S. A., L. J. Lis, J. W. Kauffman, and R. C. Macdonald. “A calorimetric and monolayer investigation of the influence of ions on the thermodynamic properties of phosphatidylcholine.” Biochim Biophys Acta 375, no. 3 (February 14, 1975): 317–26. https://doi.org/10.1016/0005-2736(75)90350-8.
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  - Bennett, P. B., R. S. Simon, and D. Youngblood. “Optimal use of nitrogen to suppress the high pressure nervous syndrome.” Aviat Space Environ Med 46, no. 1 (January 1975): 37–40.
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  - Benos, D. J., S. A. Simon, and L. J. Mandel. “The effect of amiloride and some of its analogues on cation transport in black lipid membranes and isolated frog skin.” Biophysical Journal 15, no. 2 II (January 1, 1975).
  - Evans, E., and S. Simon. “Mechanics of bilayer membranes.” Journal of Colloid and Interface Science 51, no. 2 (January 1, 1975): 266–71. https://doi.org/10.1016/0021-9797(75)90112-5.
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  - Simon, S. A., and D. C. Tosteson. “Effects of gases on thin lipid bilayer membranes.” Federation Proceedings 33, no. 5 II (January 1, 1974).
  - Johnson, M. E., S. Simon, J. W. Kauffman, and R. C. MacDonald. “A synthetic lecithin containing branched-chain fatty acids: physical properties and membrane studies.” Biochim Biophys Acta 291, no. 3 (February 16, 1973): 587–91. https://doi.org/10.1016/0005-2736(73)90463-x.
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- Book Sections
  - Anibal Disalvo, E., and S. Simon. “Preface.” In Permeability and Stability of Lipid Bilayers, iii, 2017. https://doi.org/10.1201/9780203743805.
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  - Simon, S. A., and R. Gutierrez. “TRP channels at the periphery of the taste and trigeminal systems.” In Neurobiology of TRP Channels, 113–24, 2017. https://doi.org/10.4324/9781315152837.
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  - Kramer, Randall, Ning Xiao, and Xiao-Nong Zhou. “Preface. Malaria control and elimination programme in the People’s Republic of China.,” 86:xvii–xxi, 2014. https://doi.org/10.1016/b978-0-12-800869-0.22001-5.
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  - Simon, S. A. “Series preface.” In Humanoid Robotics and Neuroscience: Science, Engineering and Society, vii, 2014. https://doi.org/10.1201/b17949.
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  - Simon, S. A. “Series preface,” vii, 2013. https://doi.org/10.1201/b14859.
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  - Simon, S. A., and M. A. L. Nicolelis. “Frontiers in neuroscience.” In Alzheimer’s Disease: Targets for New Clinical Diagnostic and Therapeutic Strategies, xv–xv, 2012.
  - Oliveira-Maia, A. J., S. A. Simon, and M. A. L. Nicolelis. “Neural ensemble recordings from central gustatory-reward pathways in awake and behaving animals.” In Methods for Neural Ensemble Recordings, Second Edition, 189–218, 2007.
  - Jones, S., H. Lo, and S. A. Simon. “Nicotinic receptors in the periphery.” In Nicotinic Receptors in the Nervous System, 81–112, 2001.
- Conference Papers
  - Morales-Lázaro, Sara L., Itzel Llorente, Félix Sierra, Ana E. López-Romero, León D. Islas, Sidney A. Simon, and Tamara Rosenbaum. “Inhibition of TRPV1 by an Unsaturated Fatty Acid.” In Biophysical Journal, 110:284a-285a. Elsevier BV, 2016. https://doi.org/10.1016/j.bpj.2015.11.1541.
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  - Morales-Lázaro, Sara L., Itzel Llorente, Félix Sierra-Ramírez, Carlos M. Diaz-Garcia, Barbara Serrano-Flores, Marcia Hiriart, Sidney A. Simon, and Tamara Rosenbaum. “Steroidal Molecules as Possible Regulators of TRPV1 Channels.” In Biophysical Journal, 106:333a-333a. Elsevier BV, 2014. https://doi.org/10.1016/j.bpj.2013.11.1911.
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  - Oliveira-Maia, Albino J., Tam-Hao T. Phan, Shobha Mummalaneni, Pamela Melone, Miguel A. L. Nicolelis, Sidney A. Simon, John A. DeSimone, and Vijay Lyall. “Effect of Nicotinic Acetylcholine Receptor (nAChR) Blockers, Mecamylamine (Mec) and Dihydro-b-erthroidine (DH beta E) on the Chorda Tympani Responses to Nicotine in TRPM5 Knockout (KO) Mice.” In Chemical Senses, 34:A79–A79. OXFORD UNIV PRESS, 2009.
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  - Simon, S. A., I. E. de Araujo, J. R. Stapleton, and M. A. L. Nicolelis. “Multisensory Processing of Gustatory Stimuli.” In Chemosens Percept, 1:95–102, 2008. https://doi.org/10.1007/s12078-008-9014-4.
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  - Simon, Sidney A. “AGFD 61-Multisensory processing in the gustatory system.” In Abstracts of Papers of the American Chemical Society, Vol. 234. AMER CHEMICAL SOC, 2007.
    Link to Item
  - Oliveira-Maia, Albino Jorge, Ivan E. de Araujo, Alexie Riofrio, Miguel A. L. Nicolelis, and Sidney A. Simon. “Cortical responses to the post-ingestive effects of sucrose in TRPM5-/- mice.” In International Journal of Obesity, 31:S102–S102. NATURE PUBLISHING GROUP, 2007.
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