Structural studies of amphiphilic 4-helix bundle peptides incorporating designed extended chromophores for nonlinear optical biomolecular materials.

Published

Journal Article

Extended conjugated chromophores containing (porphinato)zinc components that exhibit large optical polarizabilities and hyperpolarizabiliites are incorporated into amphiphilic 4-helix bundle peptides via specific axial histidyl ligation of the metal. The bundle's designed amphiphilicity enables vectorial orientation of the chromophore/peptide complex in macroscopic monolayer ensembles. The 4-helix bundle structure is maintained upon incorporation of two different chromophores at stoichiometries of 1-2 per bundle. The axial ligation site appears to effectively control the position of the chromophore along the length of the bundle.

Full Text

Duke Authors

Cited Authors

  • Strzalka, J; Xu, T; Tronin, A; Wu, SP; Miloradovic, I; Kuzmenko, I; Gog, T; Therien, MJ; Blasie, JK

Published Date

  • November 2006

Published In

Volume / Issue

  • 6 / 11

Start / End Page

  • 2395 - 2405

PubMed ID

  • 17090064

Pubmed Central ID

  • 17090064

Electronic International Standard Serial Number (EISSN)

  • 1530-6992

International Standard Serial Number (ISSN)

  • 1530-6984

Digital Object Identifier (DOI)

  • 10.1021/nl062092h

Language

  • eng