Incorporation of designed extended chromophores into amphiphilic 4-helix bundle peptides for nonlinear optical biomolecular materials.

Journal Article (Journal Article)

Multipigment ensembles that feature (porphinato)metal components and appropriate ethyne- and oligoyne-based chromophore-to-chromophore connectivity can manifest large optical polarizabilities and hyperpolarizabilities by design. Their vectorial orientation and local environment are controlled upon incorporation into designed amphiphilic 4-helix bundle peptides via axial histidyl ligation without disturbing the peptide's helical secondary structure. The chromophore/peptide stoichiometry can be tuned by varying the peptide's oligomeric state. The chromophore/peptide complexes are thermally stable, making them ideal candidates for the fabrication of nonlinear optical biomolecular materials.

Full Text

Duke Authors

Cited Authors

  • Xu, T; Wu, SP; Miloradovic, I; Therien, MJ; Blasie, JK

Published Date

  • November 2006

Published In

Volume / Issue

  • 6 / 11

Start / End Page

  • 2387 - 2394

PubMed ID

  • 17090063

Electronic International Standard Serial Number (EISSN)

  • 1530-6992

International Standard Serial Number (ISSN)

  • 1530-6984

Digital Object Identifier (DOI)

  • 10.1021/nl062091p


  • eng