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Use of caffeine to lengthen seizures in ECT.

Publication ,  Journal Article
Hinkle, PE; Coffey, CE; Weiner, RD; Cress, M; Christison, C
Published in: Am J Psychiatry
September 1987

During a course of ECT, seizure duration may become too brief for clinical benefit. Use of higher-energy stimuli may lengthen seizures but may also increase the risk of toxicity, and it is not possible when maximum settings are reached. The authors present the cases of six drug-free depressed inpatients whose seizure durations in ECT declined despite maximum settings on three different ECT devices. In all cases, pretreatment with caffeine lengthened seizures (mean increase = 107%), and clinical improvement followed. Caffeine was well tolerated, even in patients with cardiovascular diseases.

Duke Scholars

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

September 1987

Volume

144

Issue

9

Start / End Page

1143 / 1148

Location

United States

Related Subject Headings

  • Time Factors
  • Psychiatry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Electroencephalography
  • Electroconvulsive Therapy
  • Drug Combinations
  • Dose-Response Relationship, Drug
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hinkle, P. E., Coffey, C. E., Weiner, R. D., Cress, M., & Christison, C. (1987). Use of caffeine to lengthen seizures in ECT. Am J Psychiatry, 144(9), 1143–1148. https://doi.org/10.1176/ajp.144.9.1143
Hinkle, P. E., C. E. Coffey, R. D. Weiner, M. Cress, and C. Christison. “Use of caffeine to lengthen seizures in ECT.Am J Psychiatry 144, no. 9 (September 1987): 1143–48. https://doi.org/10.1176/ajp.144.9.1143.
Hinkle PE, Coffey CE, Weiner RD, Cress M, Christison C. Use of caffeine to lengthen seizures in ECT. Am J Psychiatry. 1987 Sep;144(9):1143–8.
Hinkle, P. E., et al. “Use of caffeine to lengthen seizures in ECT.Am J Psychiatry, vol. 144, no. 9, Sept. 1987, pp. 1143–48. Pubmed, doi:10.1176/ajp.144.9.1143.
Hinkle PE, Coffey CE, Weiner RD, Cress M, Christison C. Use of caffeine to lengthen seizures in ECT. Am J Psychiatry. 1987 Sep;144(9):1143–1148.
Journal cover image

Published In

Am J Psychiatry

DOI

ISSN

0002-953X

Publication Date

September 1987

Volume

144

Issue

9

Start / End Page

1143 / 1148

Location

United States

Related Subject Headings

  • Time Factors
  • Psychiatry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Electroencephalography
  • Electroconvulsive Therapy
  • Drug Combinations
  • Dose-Response Relationship, Drug