Antireflux surgery in the setting of lung transplantation: strategies for treating gastroesophageal reflux disease in a high-risk population.


Journal Article (Review)

In lung transplant recipients, GERD is associated with increased incidence of acute rejection, earlier onset of chronic rejection, and higher mortality. Surgical treatment of GERD in lung recipients seems to prevent early allograft dysfunction and improve overall survival. A total (360 degrees) fundoplication is shown to be a safe and effective method for treating GERD in lung transplant recipients and is the authors' procedure of choice, in most cases, for this high-risk patient population. The principal goal should be to minimize reflux of enteric contents that may lead to micro- or macroaspiration events in this complicated group of patients. Perioperative care should involve a multidisciplinary approach, including physicians and other health care providers familiar with the complexities of lung transplant recipients.

Full Text

Duke Authors

Cited Authors

  • Hartwig, MG; Appel, JZ; Davis, RD

Published Date

  • August 2005

Published In

Volume / Issue

  • 15 / 3

Start / End Page

  • 417 - 427

PubMed ID

  • 16104132

Pubmed Central ID

  • 16104132

International Standard Serial Number (ISSN)

  • 1547-4127

Digital Object Identifier (DOI)

  • 10.1016/j.thorsurg.2005.03.001


  • eng

Conference Location

  • United States