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Matthew Hartwig

Professor of Surgery
Surgery, Cardiovascular and Thoracic Surgery
Box 3863 Med Ctr, Durham, NC 27710
DUMC 3863, Durham, NC 27710

Overview


Dr. Hartwig is a thoracic surgeon with a clinical focus in lung transplantation and robotic assisted minimally invasive thoracic surgery for the treatment of diseases of the chest.  He serves as the Surgical Director of the Duke Lung Transplant Program and the Esophageal Center at Duke.  Additionally, he directs the Surgical Office of Clinical Research, which manages the clinical research portfolio for the Department of Surgery.  He also leads a successful program of clinical, basic and translational research in thoracic surgery and lung transplantation. He currently directs the Duke Ex Vivo Organ Laboratory (DEVOL), is the Chief of Lung Transplant Research, and is a faculty member at the Duke Clinical Research Institute (DCRI).

Dr. Hartwig has over 150 peer reviewed publications, received numerous awards, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He has also personally mentored over pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

Current Duke Appointments & Affiliations


Professor of Surgery · 2022 - Present Surgery, Cardiovascular and Thoracic Surgery, Surgery
Vice Chair for Clinical Research and Data Science in the Department of Surgery · 2026 - Present Surgery, Clinical Science Departments
Professor of Biomedical Engineering · 2024 - Present Biomedical Engineering, Pratt School of Engineering

Recent News Items


Published February 1, 2016
Poorer black patients have lower survival from esophageal cancer
Published January 27, 2016
Survival Period for Esophageal Cancer Is Tied to Race and Income

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Recent Scholarly Works


Improving equity of access/transparency in organ allocation.

Journal article Curr Opin Pulm Med · July 1, 2026 PURPOSE OF REVIEW: Persistent inequities in lung transplant access arise from biologic constraints, geographic variation, and system-level practices that are not fully addressed by urgency-based allocation alone. The recent implementation of continuous dis ... Full text Link to item Cite
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Recent Grants


US National OCS Lung Thoracic Organ Perfusion (TOP) Registry

Clinical TrialPrincipal Investigator · Awarded by TransMedics · 2024 - 2034

Ex Vivo Delivery of Viral-Mediated Gene Therapy for the Amelioration of Post-Transplant Rejection

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2026 - 2031

Transmedics DENOVO Trial - Pro00119843

Clinical TrialPrincipal Investigator · Awarded by TransMedics, Inc. · 2026 - 2031

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Education


Duke University · 2001 M.D.