Osteopetrosis: MR characteristics at 1.5 T.


Journal Article

Four patients with proved osteopetrosis (three with the infantile malignant form and one with the benign form) were examined with magnetic resonance imaging at 1.5 T. All patients were studied in the coronal and sagittal planes using both short and long repetition time/echo time sequences. The infantile malignant form was characterized by a complete lack of signal from the marrow alternating with a signal intensity equivalent to that of the intervertebral disks, resulting in a "stepladder" appearance. In the benign form or after successful marrow transplantation in the infantile malignant form, intermediate or high signal intensity in the vertebrae was noted, suggesting the presence of some marrow elements.

Full Text

Duke Authors

Cited Authors

  • Rao, VM; Dalinka, MK; Mitchell, DG; Spritzer, CE; Kaplan, F; August, CS; Axel, L; Kressel, HY

Published Date

  • October 1, 1986

Published In

Volume / Issue

  • 161 / 1

Start / End Page

  • 217 - 220

PubMed ID

  • 3763870

Pubmed Central ID

  • 3763870

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.161.1.3763870


  • eng

Conference Location

  • United States