Contemporary radiotherapy in head and neck cancer: balancing chance for cure with risk for complication.

Journal Article (Journal Article;Review)

Radiotherapy plays an integral role in the management of most patients with cancers of the head and neck. Better understanding of radiobiology and radiation physics has allowed radiation oncologists to enhance the tumoricidal effects of radiation and reduce the severity of normal tissue toxicities. This article reviews the biologic foundation of head and neck radiotherapy, the physical principles and technological innovations that enable delivery of highly conformal radiation, the acute and late complications of radiation-based treatments, and the clinical evidence supporting contemporary practice.

Full Text

Duke Authors

Cited Authors

  • Cabrera, AR; Yoo, DS; Brizel, DM

Published Date

  • July 2013

Published In

Volume / Issue

  • 22 / 3

Start / End Page

  • 579 - 598

PubMed ID

  • 23622081

Electronic International Standard Serial Number (EISSN)

  • 1558-5042

Digital Object Identifier (DOI)

  • 10.1016/j.soc.2013.02.001


  • eng

Conference Location

  • United States