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Pathophysiology of heterotopic ossification.

Publication ,  Journal Article
Zychowicz, ME
Published in: Orthopedic nursing
May 2013

Heterotopic ossification (HO) is a pathologic condition that leads to the development of bone within nonosseous soft tissues. A common site for HO development is at the hip. The bone that forms is believed to develop through stimulation by cellular mediators and altered neurovascular signaling. Heterotopic ossification can be a debilitating disease leading to pain, edema, and stiffness. This only compounds already-debilitating comorbid conditions such as a spinal cord injury, head injury, or trauma. Several factors, including prostaglandin E2, bone morphogenetic protein, and the inflammatory process, are believed to contribute to the development of HO. The full scope of pathophysiology contributing to HO is not fully understood.

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Published In

Orthopedic nursing

DOI

EISSN

1542-538X

ISSN

0744-6020

Publication Date

May 2013

Volume

32

Issue

3

Start / End Page

173 / 177

Related Subject Headings

  • Risk Factors
  • Pain
  • Ossification, Heterotopic
  • Nursing
  • Humans
  • Education, Nursing, Continuing
  • Diagnostic Imaging
  • 4205 Nursing
  • 1110 Nursing
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zychowicz, M. E. (2013). Pathophysiology of heterotopic ossification. Orthopedic Nursing, 32(3), 173–177. https://doi.org/10.1097/nor.0b013e3182920d85
Zychowicz, Michael E. “Pathophysiology of heterotopic ossification.Orthopedic Nursing 32, no. 3 (May 2013): 173–77. https://doi.org/10.1097/nor.0b013e3182920d85.
Zychowicz ME. Pathophysiology of heterotopic ossification. Orthopedic nursing. 2013 May;32(3):173–7.
Zychowicz, Michael E. “Pathophysiology of heterotopic ossification.Orthopedic Nursing, vol. 32, no. 3, May 2013, pp. 173–77. Epmc, doi:10.1097/nor.0b013e3182920d85.
Zychowicz ME. Pathophysiology of heterotopic ossification. Orthopedic nursing. 2013 May;32(3):173–177.

Published In

Orthopedic nursing

DOI

EISSN

1542-538X

ISSN

0744-6020

Publication Date

May 2013

Volume

32

Issue

3

Start / End Page

173 / 177

Related Subject Headings

  • Risk Factors
  • Pain
  • Ossification, Heterotopic
  • Nursing
  • Humans
  • Education, Nursing, Continuing
  • Diagnostic Imaging
  • 4205 Nursing
  • 1110 Nursing