Pathophysiology of heterotopic ossification.
Publication
, Journal Article
Zychowicz, ME
Published in: Orthopedic nursing
May 2013
Heterotopic ossification (HO) is a pathologic condition that leads to the development of bone within nonosseous soft tissues. A common site for HO development is at the hip. The bone that forms is believed to develop through stimulation by cellular mediators and altered neurovascular signaling. Heterotopic ossification can be a debilitating disease leading to pain, edema, and stiffness. This only compounds already-debilitating comorbid conditions such as a spinal cord injury, head injury, or trauma. Several factors, including prostaglandin E2, bone morphogenetic protein, and the inflammatory process, are believed to contribute to the development of HO. The full scope of pathophysiology contributing to HO is not fully understood.
Duke Scholars
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Published In
Orthopedic nursing
DOI
EISSN
1542-538X
ISSN
0744-6020
Publication Date
May 2013
Volume
32
Issue
3
Start / End Page
173 / 177
Related Subject Headings
- Risk Factors
- Pain
- Ossification, Heterotopic
- Nursing
- Humans
- Education, Nursing, Continuing
- Diagnostic Imaging
- 1110 Nursing
Citation
APA
Chicago
ICMJE
MLA
NLM
Zychowicz, M. E. (2013). Pathophysiology of heterotopic ossification. Orthopedic Nursing, 32(3), 173–177. https://doi.org/10.1097/nor.0b013e3182920d85
Zychowicz, Michael E. “Pathophysiology of heterotopic ossification.” Orthopedic Nursing 32, no. 3 (May 2013): 173–77. https://doi.org/10.1097/nor.0b013e3182920d85.
Zychowicz ME. Pathophysiology of heterotopic ossification. Orthopedic nursing. 2013 May;32(3):173–7.
Zychowicz, Michael E. “Pathophysiology of heterotopic ossification.” Orthopedic Nursing, vol. 32, no. 3, May 2013, pp. 173–77. Epmc, doi:10.1097/nor.0b013e3182920d85.
Zychowicz ME. Pathophysiology of heterotopic ossification. Orthopedic nursing. 2013 May;32(3):173–177.
Published In
Orthopedic nursing
DOI
EISSN
1542-538X
ISSN
0744-6020
Publication Date
May 2013
Volume
32
Issue
3
Start / End Page
173 / 177
Related Subject Headings
- Risk Factors
- Pain
- Ossification, Heterotopic
- Nursing
- Humans
- Education, Nursing, Continuing
- Diagnostic Imaging
- 1110 Nursing