Overview
Dr. Nandan Lad is a neurosurgeon, scientist, and entrepreneur and Professor and Vice Chair of Innovation for Duke Neurosurgery. He is Director of the Functional & Restorative Neuromodulation Program and the Duke NeuroInnovations Program, a systematic approach to innovation to large unmet clinical needs.
He completed his MD and PhD in Biochemistry at Chicago Medical School and his neurosurgical residency training at Stanford with fellowships in both Surgical Innovation and Functional Neurosurgery.
Neuromodulation; Neurorestoration; Bioengineering; Medical Device Design; Clinical Trials; Data Science; Health Outcomes.
Current Appointments & Affiliations
Professor of Neurosurgery
·
2021 - Present
Neurosurgery,
Neurosurgery
Faculty Network Member of the Duke Institute for Brain Sciences
·
2011 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Core Faculty Member, Duke-Margolis Institute for Health Policy
·
2024 - Present
Duke-Margolis Institute for Health Policy,
University Institutes and Centers
In the News
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Recent Publications
High-Frequency 10-kHz Spinal Cord Stimulation Provides Long-term (24-Month) Improvements in Diabetes-Related Pain and Quality of Life for Patients with Painful Diabetic Neuropathy.
Journal Article J Diabetes Sci Technol · January 2026 BACKGROUND: The SENZA-PDN study evaluated high-frequency 10-kHz spinal cord stimulation (SCS) for the treatment of painful diabetic neuropathy (PDN). Over 24 months, 10-kHz SCS provided sustained pain relief and improved health-related quality of life. Thi ... Full text Link to item CiteECAP-Controlled Closed-Loop Spinal Cord Stimulation for Chronic Nonsurgical Refractory Back Pain: Subgroup Analysis From Two Prospective Multicenter Clinical Trials.
Journal Article Spine (Phila Pa 1976) · December 1, 2025 STUDY DESIGN: Subgroup analysis of patients with chronic nonsurgical refractory back pain (NSRBP) from two prospective multicenter clinical trials to 12-month follow-up. OBJECTIVE: To evaluate pain-related and holistic response, safety events as well as ne ... Full text Link to item CiteProspective Trial of Cerebrospinal Fluid Filtration After Aneurysmal Subarachnoid Hemorrhage via Lumbar Catheter Extension (PILLAR-XT).
Journal Article Neurocrit Care · December 2025 BACKGROUND: There is a growing consensus that blood in the cerebrospinal fluid (CSF) is deleterious to outcomes in patients with aneurysmal subarachnoid hemorrhage. The extracorporeal filtration of subarachnoid hemorrhage via spinal catheter extension stud ... Full text Link to item CiteRecent Grants
A Randomized, Controlled, Multicenter Trial of Percutaneous Peripheral Nerve Stimulation (PNS) for the Treatment of Back Pain SPR Reset (Industry) 0151CSP-000
Clinical TrialPrincipal Investigator · Awarded by SPR Therapeutics, Inc. · 2024 - 2029The overlap of speech production and verbal working memory
ResearchCo Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2028A Phase 2, Randomized, Double-blind, Sham Surgery controlled Study of the Efficacy and Safety of Intraputaminal AAV2-GDNF in the Treatment of Adults with Moderate Stage Parkinson's Disease
Clinical TrialPrincipal Investigator · Awarded by Asklepios BioPharmaceutical, Inc. · 2024 - 2027View All Grants
Education, Training & Certifications
Rosalind Franklin University of Medicine and Science ·
2004
M.D.
Rosalind Franklin University of Medicine and Science ·
2004
Ph.D.