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Shivanand Lad
Professor of Neurosurgery
Neurosurgery
nandan.lad@duke.edu
DUMC 3807, Durham, NC 27710
200 Trent Drive, Blue Zone, Su, Durham, NC 27710
Research
More About This Person
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At a Glance
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Credentials
Education
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Academic Experience
Current Appointments & Affiliations
Previous Appointments & Affiliations
Leadership & Clinical Positions
Professional Training and Employment
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Expertise
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Research
Selected Grants
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Publications
Selected Publications
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Artistic Works / Events
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Teaching
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Advising & Mentoring
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Recognition
In the News
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Professional Activities
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Selected Grants
A Randomized, Controlled, Multicenter Trial of Percutaneous Peripheral Nerve Stimulation (PNS) for the Treatment of Back Pain SPR Reset (Industry) 0151CSP-000
Clinical Trial
Principal Investigator ·
Awarded by SPR Therapeutics, Inc. ·
2024 - 2029
The overlap of speech production and verbal working memory
Research
Co Investigator ·
Awarded by National Institute of Neurological Disorders and Stroke ·
2023 - 2028
A Phase 2, Randomized, Double-blind, Sham Surgery controlled Study of the Efficacy and Safety of Intraputaminal AAV2-GDNF in the Treatment of Adults with Moderate Stage Parkinson's Disease
Clinical Trial
Principal Investigator ·
Awarded by Asklepios BioPharmaceutical, Inc. ·
2024 - 2027
A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury (SCI)
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2026
A Wireless µECoG Prosthesis for Speech
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2021 - 2026
A Double-Blind, Randomized, Controlled Trial of Epidural Conus Medullaris Stimulation to Alleviate Pain and Augment Rehabilitation in Patients with Subacute Thoracic Spinal Cord Injury
Research
Principal Investigator ·
Awarded by Advanced Neuromodulation Systems, Inc ·
2021 - 2025
NINDS Research Education Programs for Residents and Fellows in Neurosurgery
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institute of Neurological Disorders and Stroke ·
2009 - 2025
A Randomized, Controlled, Multicenter Trial of Percutaneous Peripheral Nerve Stimulation (PNS) for the Treatment of Back Pain
Clinical Trial
Investigator ·
Awarded by SPR Therapeutics, LLC ·
2020 - 2024
Duke CTSA (TL1) Year 5
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2018 - 2024
ReActiv8: Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation (RESTORE)
Clinical Trial
Principal Investigator ·
Awarded by Mainstay Medical Ltd. ·
2022 - 2024
ADvance II Study: A 12-month double-blind, randomized, controlled study to evaluate the safety and efficacy of Deep Brain Stimulation of the fornix (DBS-f) in patients with mild probable Alzheimer's Disease
Clinical Trial
Principal Investigator ·
Awarded by Functional Neuromodulation ·
2021 - 2024
ECAP Study: A prospective, multicenter, single-arm study examining ECAP-controlled, closed-loop stimulation with the Evoke Spinal Cord Stimulator (SCS) System to treat patients with chronic pain of the trunk and/or limbs.
Clinical Trial
Principal Investigator ·
Awarded by Saluda Medical Americas ·
2021 - 2023
ReActiv8 Implantable Neuro-stimulation system for Chronic Low Back Pain
Clinical Trial
Principal Investigator ·
Awarded by Mainstay Medical Ltd. ·
2017 - 2023
Chronic Refractory Low Back Pain (CRLBP)
Research
Principal Investigator ·
Awarded by Mainstay Medical Ltd. ·
2021 - 2023
NEVRO NSRBP
Clinical Trial
Principal Investigator ·
Awarded by Nevro Corp ·
2018 - 2022
A Post-Market, Multicenter, Prospective, Randomized Clinical Trial Comparing 10 kHz Spinal Cord Stimulation (HF10¿ Therapy) Combined with Conventional Medical Management to Conventional Medical Management Alone in the Treatment of Chronic, Intractabl
Clinical Trial
Principal Investigator ·
Awarded by Nevro Corp ·
2018 - 2022
Nevro HF10 Outcomes Analysis
Research
Principal Investigator ·
Awarded by Nevro Corp ·
2020 - 2022
Validation of Novel Therapeutic Approach for Leptomeningeal Metastases
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2016 - 2022
Validation of a Novel Fungicidal Approach for Cryptococcal Meningitis
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2018 - 2022
A Randomized, Placebo-Controlled Study of the Efficacy and Safety of Intracerebral Stem Cells (CTX0E03) in Subjects with Disability Following an Ischemic Stroke (PISCES III)
Clinical Trial
Principal Investigator ·
Awarded by ReNeuron Group plc ·
2019 - 2022
IPA Lexia Zidanyue Yang
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2020 - 2021
IPA - Boua
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2020 - 2021
IPA - Marius
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2020 - 2021
IPA - Thirakul
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2020 - 2021
IPA - Allison Spell
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2021
IPA - Giamberardino
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2021
IPA - Warren Grill
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2020
IPA - Yadav
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2020
IPA - Jennifer Peters
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2020
Extent of Resection and Spinal Stabilization and Reconstruction in Spinal Tumors
Research
Principal Investigator ·
Awarded by Medtronic, Inc. ·
2015 - 2019
IPA - Katelyn Ripple
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2018 - 2019
IPA - Beiyu Liu
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2018 - 2019
IPA - George De Castro
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2018 - 2019
IPA - Pagadala
Research
Principal Investigator ·
Awarded by Durham Veterans Affairs Medical Center ·
2019 - 2019
Collaborative research effort to study patient outcomes using publicly available claims databases and additional sources of data with focus on neuromodulation.
Research
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2017 - 2018
Validation of a Novel Therapeutic Approach for Cryptococcal Meningitis
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2017 - 2018
TARGET: A Post-Approval Study to Evaluate Targeted SCS (DRG) Stimulation for the management of Moderate to Severe Chronic, Intractable, Pain of the Lower Limbs due to CRPS types I and II
Clinical Trial
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2016 - 2018
Development of a novel ventricular catheter for hydrocephalus
Research
Principal Investigator ·
Awarded by North Carolina Biotechnology Center ·
2017 - 2018
Human Fresh Tissue Lab Agreement
Inst. Training Prgm or CME
Principal Investigator ·
Awarded by Abbott Laboratories ·
2017 - 2018
Human Fresh Tissue Lab Agreement
Inst. Training Prgm or CME
Principal Investigator ·
Awarded by Nevro Corp ·
2017 - 2017
Directed Chemotherapy Delivery for Leptomeningeal Metastases
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2016 - 2017
Patient Outcomes using publicly available claims with focus on Neuromodulation
Research
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2016 - 2017
Cryptococcus Neoformans
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2015 - 2017
Mechanisms of Parkinsonian Impulsivity in Human Subthalamic Nucleus
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2014 - 2017
Enhanced Design Experiences for Duke BME Students
Inst. Training Prgm or CME
Collaborator ·
Awarded by National Institutes of Health ·
2011 - 2017
Cryptococcus Neoformans
Research
Principal Investigator ·
Awarded by Minnetronix, Inc ·
2015 - 2016
Neuromodulation Project
Research
Principal Investigator ·
Awarded by Medtronic, Inc. ·
2014 - 2016
Prospective, Randomized Study of Multicolumn Implantable Lead Stimulation for Predominant Low Back Pain (PROMISE)
Clinical Trial
Principal Investigator ·
Awarded by Medtronic, Inc. ·
2014 - 2016
Neuromodulation Fellowship
Fellowship
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2014 - 2016
SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study for the Treatment of Chronic Low Back and Leg Pain
Clinical Trial
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2014 - 2015
Human Fresh Tissue Lab
Inst. Training Prgm or CME
Principal Investigator ·
Awarded by St. Jude Medical Inc. ·
2014 - 2014