Skip to main content

Amanda Randles

Associate Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708
Wilkinson Building, Room No. 325, 534 Research Drive, Durham, NC 27708

Overview


My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer.

Current Appointments & Affiliations


Associate Professor of Biomedical Engineering · 2023 - Present Biomedical Engineering, Pratt School of Engineering
Assistant Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science · 2022 - Present Thomas Lord Department of Mechanical Engineering and Materials Science, Pratt School of Engineering
Associate Professor of Computer Science · 2025 - Present Computer Science, Trinity College of Arts & Sciences
Member of the Duke Cancer Institute · 2015 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published April 10, 2025
New Center Brings Technological Advances to the Future of Health Care
Published March 12, 2025
Creating Digital Twins to Save Lives
Published December 19, 2024
Building Digital Twins for Individualized Health Care

View All News

Recent Publications


Photon-Counting CT for Evaluation of Coiled Intracranial Aneurysms.

Journal Article AJNR Am J Neuroradiol · April 2, 2026 BACKGROUND AND PURPOSE: Intracranial aneurysms treated with endovascular embolization often require surveillance imaging using DSA, an invasive, risky, and expensive procedure. Existing noninvasive imaging modalities (standard or MRA) are often unsatisfact ... Full text Open Access Link to item Cite

High-throughput adaptive physics refinement for tissue-scale adhesive dynamics

Journal Article Journal of Computational Science · April 1, 2026 Explicitly resolving ligand–receptor interactions of circulating tumor cells (CTCs) across anatomically realistic vasculature remains computationally prohibitive at the submicrometer fidelity required for adhesive dynamics. In this work, we extend our prev ... Full text Cite

Real-Time Peripheral Revascularization Planning in Chronic Limb Threatening Ischemia Using HarVI: A Digital Twin Approach.

Journal Article Cardiovascular engineering and technology · March 2026 BackgroundPeripheral artery disease (PAD) is a leading cause of limb loss and morbidity worldwide, with chronic limb-threatening ischemia (CLTI) representing its most severe presentation. Although image-guided endovascular interventions are routin ... Full text Open Access Cite
View All Publications

Recent Grants


iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030

FDT-BioTech: Scalable Digital Twins to Power Virtual Trials and Test Treatments

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2025 - 2028

Dynamic models of the cardiovascular system capturing years, rather than heartbeats

ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2022 - 2027

View All Grants

Education


Harvard University · 2013 Ph.D.