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Thuy Le

Associate Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710, Durham, NC 27710
315 Trent Drive, Room #257, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor of Medicine · 2024 - Present Medicine, Infectious Diseases, Medicine
Associate Professor of Molecular Genetics and Microbiology · 2019 - Present Molecular Genetics and Microbiology, Basic Science Departments
Affiliate, Duke Global Health Institute · 2019 - Present Duke Global Health Institute, University Institutes and Centers

In the News


Published October 16, 2025
Infographics about Antimicrobial Stewardship in Talaromyces marneffei, created by the International Society for Infectious Diseases
Published February 1, 2025
Diagnosing the invasive fungal infection talaromycosis earlier to save lives
Published December 9, 2024
Dr. Thuy Le, a Passionate Leader in HIV-Associated Fungal Infections in Vietnam and Worldwide: Part 2

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Recent Publications


Development and Clinical Evaluation of a Novel Talaromyces marneffei Mp1p Lateral Flow Assay for Rapid Diagnosis of Talaromycosis.

Journal Article Clin Infect Dis · January 6, 2026 BACKGROUND: The diagnosis of talaromycosis, a life-threatening invasive fungal disease endemic in Southeast Asia, still relies on protracted culture methods. We report the development and clinical evaluation of a novel lateral flow assay (LFA) for the rapi ... Full text Link to item Cite

Comparative performance of a commercial and in-house Mp1p antigen-detecting enzyme immunoassay for the rapid diagnosis of talaromycosis.

Journal Article PLoS Negl Trop Dis · August 2025 BACKGROUND: Several antigen-detection assays have been developed for the rapid diagnosis of talaromycosis, but their utility has been limited by a lack of commercial options. The aim of this study was to perform a head-to-head comparison of the performance ... Full text Link to item Cite
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Recent Grants


Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01

ResearchPrincipal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2031

Interdisciplinary Research Training Program in AIDS

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2010 - 2030

Tri-Institutional Molecular Mycology and Pathogenesis Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

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Education, Training & Certifications


University of Oxford (United Kingdom) · 2016 D.Phil.
University of Arizona, College of Medicine · 2002 M.D.