Overview
Dr. Whitson's research is focused on improving care options and resilience for people with multiple chronic conditions. In particular, she has interest and expertise related to the link between age-related changes in the eye and brain (e.g., How does late-life vision loss impact the aging brain or cognitive outcomes? Is Alzheimer's disease associated with distinctive changes in the retina, and could such changes help diagnose Alzheimer's disease early in its course?). Dr. Whitson leads a collaborative Alzheimer's Disease initiative that brings together investigators from Duke University and the University of North Carolina (UNC) at Chapel Hill, with a bold vision to transform dementia research and care across Eastern North Carolina. Dr. Whitson is also interested in improving health services to better meet the needs of medically complex patients. Within the Duke Aging Center, she leads research efforts aimed at promoting resilience to late-life stressors (e.g., surgery, sensory loss, infection). She has developed a novel rehabilitation model for people with co-existing vision and cognitive deficits, and she is part of a inter-disciplinary team seeking to improve peri-operative outcomes for frail or at-risk seniors who must undergo surgery. As a co-leader of a national resilience collaborative, she seeks to better understand the biological and psychological factors that determine how well we "bounce back" after health stressors.
Current Appointments & Affiliations
Duke School of Medicine Distinguished Professor in Neuroscience
·
2024 - Present
Medicine, Geriatrics and Palliative Care,
Medicine
Professor of Medicine
·
2020 - Present
Medicine, Geriatrics and Palliative Care,
Medicine
Professor in Ophthalmology
·
2020 - Present
Ophthalmology, Vitreoretinal Diseases & Surgery,
Ophthalmology
Professor in Head & Neck Surgery and Communication Sciences
·
2021 - Present
Head and Neck Surgery & Communication Sciences,
Clinical Science Departments
Professor in Neurology
·
2022 - Present
Neurology,
Clinical Science Departments
Director of the Duke Center for the Study of Aging and Human Development
·
2008 - Present
Center for the Study of Aging and Human Development,
Institutes and Centers
Recent Publications
Mixed-methods Analysis of Preoperative Distress and Postoperative Outcomes in a Prospective, Observational Cohort of Older Adults.
Journal Article Anesthesiology · January 1, 2026 BACKGROUND: The effect of psychological distress on general geriatric surgery outcomes remains unexplored despite recommendations for routine, preoperative distress screening. This study aimed to assess preoperative distress measures in a general geriatric ... Full text Link to item CitePrevalence of pre-stroke and stroke-related vision impairments and their association with mild cognitive impairment and dementia.
Journal Article J Alzheimers Dis · December 12, 2025 BackgroundVision impairment is a risk factor for mild cognitive impairment (MCI) among stroke survivors, but it is unclear if this association is driven by vision impairment present before or due to the stroke, and if similar associations exist with dement ... Full text Link to item CiteInvestigating stroke-related vision impairments and time to incident dementia diagnosis.
Journal Article J Stroke Cerebrovasc Dis · December 2025 Vision loss is a risk factor for dementia, but it is unknown whether stroke-related vision impairment is linked to dementia risk in stroke survivors. This secondary analysis aimed to quantify the association between stroke-related vision impairment and tim ... Full text Link to item CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030The role of cerebrospinal fluid complement activation in delirium and post-intensive care unit long-term cognitive impairment
ResearchCo-Mentor · Awarded by National Institute on Aging · 2024 - 2029Neural Mechanisms Underlying Attentional Resilience in the Aging Brain
ResearchCo Investigator · Awarded by National Institute on Aging · 2024 - 2029View All Grants
Education, Training & Certifications
Duke University ·
2009
M.H.S.
Cornell University ·
2000
M.D.