Overview
Research interests in Prof. Craig's group bridge physical organic and materials chemistry. Many of these interests are guided by the vision that important challenges in materials science might be better tackled not from the traditional perspective of an engineer, but rather from the molecular perspective of an organic chemist. Current interests include the design and synthesis of self-healing polymers and the use of modern mechanochemistry in new stress-responsive polymers, catalysis, and the study of transition states and reactive intermediates. These areas require an interdisciplinary and nontraditional mix of synthetic organic and polymer chemistry, single-molecule spectroscopy, supramolecular chemistry, and materials characterization.
Research interests are complemented by numerous teaching and outreach activities, including: (1) hosting intensive undergraduate and high school research experiences for a diverse group of both Duke and non-Duke students; (2) exploiting effective, scalable, and low-cost mechanisms for content dissemination; (3) team-based and active learning content in the undergraduate and graduate classroom.
Current Appointments & Affiliations
William T. Miller Distinguished Professor of Chemistry
·
2013 - Present
Chemistry,
Trinity College of Arts & Sciences
Professor in the Department of Chemistry
·
2012 - Present
Chemistry,
Trinity College of Arts & Sciences
Bass Fellow
·
2012 - Present
Chemistry,
Trinity College of Arts & Sciences
In the News
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Recent Publications
Optimizing the Stability of Viral Nanoparticles: Engineering Strategies, Applications, and the Emerging Concept of the Virophore.
Journal Article Journal of the American Chemical Society · January 2026 Nanoparticles derived from plant viruses and bacteriophages are self-assembling structures that can be functionalized for broad applications in drug delivery, vaccine formulation, and imaging, as well as the engineering of nanomaterials, and nanoscale temp ... Full text CiteReimagining Polymer Networks from Molecule to Material
Journal Article Macromolecules · December 23, 2025 Polymer networks are complex materials with a broad distribution of molecular states, making it challenging to establish direct connections between the structure of individual network components and macroscopic material behavior. Recent advancements in mec ... Full text CiteSwitching and Quantifying the Single-Molecule Mechanochemical Reactivity of Four-Membered Carbocycle Mechanophores within a Single, Photoswitchable Polymer Strand.
Journal Article Journal of the American Chemical Society · December 2025 The reactivity of four-membered carbocycle mechanophores, such as cyclobutane (CB), cyclobutene (CBE), and benzocyclobutene (BCB), has been explored in the context of fundamental reaction mechanisms and the manipulation of polymer network properties. Despi ... Full text CiteRecent Grants
NSF-BSF: Emergent Rheology of Blends Containing Supramolecular Polymers
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2024 - 2027Covalent Polymer Mechanochemistry
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2023 - 2027Multi-State Catalysts Modulated by Mechanical Force
ResearchCo Investigator · Awarded by Department of Energy · 2017 - 2027View All Grants
Education, Training & Certifications
Stanford University ·
1997
Ph.D.
University of Cambridge (United Kingdom) ·
1992
M.Phil.
Duke University ·
1991
B.S.