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Stephen L Craig

William T. Miller Distinguished Professor of Chemistry
Chemistry
Box 90346, Durham, NC 27708-0346
3221 French Family Science Cen, 124 Science Drive, Durham, NC 27708

Overview


Research interests in Prof. Craig's group bridge physical organic and materials chemistry. Many of these interests are guided by the vision that important challenges in materials science might be better tackled not from the traditional perspective of an engineer, but rather from the molecular perspective of an organic chemist. Current interests include the design and synthesis of self-healing polymers and the use of modern mechanochemistry in new stress-responsive polymers, catalysis, and the study of transition states and reactive intermediates. These areas require an interdisciplinary and nontraditional mix of synthetic organic and polymer chemistry, single-molecule spectroscopy, supramolecular chemistry, and materials characterization. Research interests are complemented by numerous teaching and outreach activities, including: (1) hosting intensive undergraduate and high school research experiences for a diverse group of both Duke and non-Duke students; (2) exploiting effective, scalable, and low-cost mechanisms for content dissemination; (3) team-based and active learning content in the undergraduate and graduate classroom.

Current Appointments & Affiliations


William T. Miller Distinguished Professor of Chemistry · 2013 - Present Chemistry, Trinity College of Arts & Sciences
Professor in the Department of Chemistry · 2012 - Present Chemistry, Trinity College of Arts & Sciences
Bass Fellow · 2012 - Present Chemistry, Trinity College of Arts & Sciences

In the News


Published June 22, 2023
How to Make Rubbery Materials That Can Take a Beating Without Losing Their Bounce
Published September 1, 2021
NSF Creates Polymer Chemistry Optimization Center at Duke for Future Materials
Published May 14, 2020
Duke Celebrates 70 Years of Discovery and Research at the National Science Foundation

View All News

Recent Publications


Extending BigSMILES to Include Topological Bonds.

Journal Article ACS macro letters · March 2026 Machine-readable line notations such as SMILES are rapidly gaining popularity as a means of storing, searching, and analyzing chemical information. Within the SMILES framework, BigSMILES was developed to represent the stochastic connectivity characteristic ... Full text Cite

Tetrafunctional cyclobutanes tune toughness via network strand continuity.

Journal Article Nature chemistry · February 2026 Customizing the toughness of polymer networks independently of their chemical composition and topology remains an unsolved challenge. Traditionally, polymer network toughening is achieved by using specialized monomers or solvents or adding secondary networ ... Full text Cite

Optimizing the Stability of Viral Nanoparticles: Engineering Strategies, Applications, and the Emerging Concept of the Virophore.

Journal Article Journal of the American Chemical Society · January 2026 Nanoparticles derived from plant viruses and bacteriophages are self-assembling structures that can be functionalized for broad applications in drug delivery, vaccine formulation, and imaging, as well as the engineering of nanomaterials, and nanoscale temp ... Full text Cite
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Recent Grants


NSF-BSF: Emergent Rheology of Blends Containing Supramolecular Polymers

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2024 - 2027

Covalent Polymer Mechanochemistry

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2023 - 2027

Multi-State Catalysts Modulated by Mechanical Force

ResearchCo Investigator · Awarded by Department of Energy · 2017 - 2027

View All Grants

Education


Stanford University · 1997 Ph.D.
University of Cambridge (United Kingdom) · 1992 M.Phil.
Duke University · 1991 B.S.

External Links


Craig Research Group