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Growing polymers from peptides and proteins: A biomedical perspective

Publication ,  Journal Article
Qi, Y; Chilkoti, A
Published in: Polymer Chemistry
January 21, 2014

This review covers the development of the in situ growth of polymers from biomolecules, also termed the "grafting from" conjugation methodology. We trace the evolution of this field of research, with an emphasis on recently developed methods to synthesize polymer conjugates of peptides and proteins with control over the site of conjugation, the stoichiometry of the conjugate, and the chain length and polydispersity of the polymer. We highlight the functional properties and potential biomedical applications of the peptide/protein-polymer conjugates, including conjugates with more advanced architecture and self-assembly behaviour. © 2014 The Royal Society of Chemistry.

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Published In

Polymer Chemistry

DOI

EISSN

1759-9962

ISSN

1759-9954

Publication Date

January 21, 2014

Volume

5

Issue

2

Start / End Page

266 / 276

Related Subject Headings

  • 4018 Nanotechnology
  • 3406 Physical chemistry
  • 3403 Macromolecular and materials chemistry
  • 0307 Theoretical and Computational Chemistry
  • 0303 Macromolecular and Materials Chemistry
 

Citation

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Qi, Y., & Chilkoti, A. (2014). Growing polymers from peptides and proteins: A biomedical perspective. Polymer Chemistry, 5(2), 266–276. https://doi.org/10.1039/c3py01089a
Qi, Y., and A. Chilkoti. “Growing polymers from peptides and proteins: A biomedical perspective.” Polymer Chemistry 5, no. 2 (January 21, 2014): 266–76. https://doi.org/10.1039/c3py01089a.
Qi Y, Chilkoti A. Growing polymers from peptides and proteins: A biomedical perspective. Polymer Chemistry. 2014 Jan 21;5(2):266–76.
Qi, Y., and A. Chilkoti. “Growing polymers from peptides and proteins: A biomedical perspective.” Polymer Chemistry, vol. 5, no. 2, Jan. 2014, pp. 266–76. Scopus, doi:10.1039/c3py01089a.
Qi Y, Chilkoti A. Growing polymers from peptides and proteins: A biomedical perspective. Polymer Chemistry. 2014 Jan 21;5(2):266–276.
Journal cover image

Published In

Polymer Chemistry

DOI

EISSN

1759-9962

ISSN

1759-9954

Publication Date

January 21, 2014

Volume

5

Issue

2

Start / End Page

266 / 276

Related Subject Headings

  • 4018 Nanotechnology
  • 3406 Physical chemistry
  • 3403 Macromolecular and materials chemistry
  • 0307 Theoretical and Computational Chemistry
  • 0303 Macromolecular and Materials Chemistry