Ashutosh Chilkoti | Scholars@Duke

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering

Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University.

My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.

Current Research Interests

Focused on biomolecular materials and biointerface science and emphasizes the development of applications that span the range from bioseparations, biosensors, biomaterials, and targeted drug delivery.

Current Appointments & Affiliations

Alan L. Kaganov Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2016
Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2006
Chair of the Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2014
Professor in the Department of Chemistry, Chemistry, Trinity College of Arts & Sciences 2006
Professor in the Department of Mechanical Engineering and Materials Science, Pratt School of Engineering, Duke University 2016
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1996
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2018

Contact Information

1427 CIEMAS, Durham, NC 27708
Box 90281, Durham, NC 27708-0281
(919) 660-5373
Google Scholar
http://chilkotilab.pratt.duke.edu

Background
Education, Training, & Certifications
- Ph.D., University of Washington 1991
Duke Appointment History
- Professor in the Department of Mechanical Engineering and Materials Science, Mechanical Engineering and Materials Science, Pratt School of Engineering 2012 - 2015
- Director of the Center for Biologically Inspired Materials and Material Systems, Biomedical Engineering, Pratt School of Engineering 2007 - 2010
- Associate Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2002 - 2006
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 1996 - 2002
Recognition
In the News
- OCT 30, 2018 Pratt School of Engineering
  
  A Year of Real-World Biomedical Engineering Design
- OCT 15, 2018 Pratt School of Engineering
  
  Biomaterials with "Frankenstein Proteins" Help Heal Tissue
- SEP 11, 2017 Pratt School of Engineering
  
  Pushing Science and Engineering to Create New Soft Materials
- AUG 8, 2017 Pratt School of Engineering
  
  Inkjet-Printed Tool Enables Sensitive Diagnostic Testing in Point-of-Care Settings
- AUG 8, 2017 The Engineer
  
  Portable diagnostic tool detects disease in 15 minutes
- JUN 5, 2017 Pratt School of Engineering
  
  Injectable Solution May Provide Weeks of Glucose Control
- JAN 30, 2017 Pratt School of Engineering
  
  Engineered 'Spaghetti-Ball' Proteins Provide Biomedical Insights
- NOV 30, 2016
  
  Drug Delivery Modification Sidesteps Allergic Responses
- MAR 29, 2016 WRAL Tech Wire
  
  Duke buys back PhaseBio's anticancer option
- JAN 14, 2016 The Scientist
  
  Reducing repetition while building biopolymers
- JAN 5, 2016
  
  Computer Program Removes a Hurdle in Synthesizing Proteins and Polypeptides
- SEP 21, 2015
  
  Gene Sequences May Control Assembly and Disassembly of Proteins
- AUG 10, 2015
  
  Molecular Tinkering Doubles Cancer Drug’s Efficacy
- AUG 5, 2015 AZoNano
  
  Packaging cancer drug into nanoparticles doubles tumor destroying efficacy
- DEC 16, 2014
  
  Calderbank, Chilkoti Named Fellows of the National Academy of Inventors
- OCT 9, 2014
  
  Duke Startup Innovates Blood-Testing Technology—and Tech Transfer Process
- AUG 8, 2014
  
  Chilkoti Named Chair of Biomedical Engineering
Awards & Honors
Expertise
Global Scholarship
- Research
  - India (Country)
- Teaching
  - India (Country)
Research
Selected Grants
- Genetically Encoded Smart Biohybrid Materials awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
- University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health 1994 - 2022
- Immunomodulatory Biomaterials via Peptide and Protein Self-Assembly awarded by National Institutes of Health 2009 - 2022
- DMREF: Collaborative Research: High throughput Exploration of Sequence Space of Peptide Polymers that Exhibit Aqueous Demixing Phase Behavior awarded by National Science Foundation 2017 - 2021
- Magnetically directed single cell transcriptome analysis in HIV latency awarded by National Institutes of Health 2014 - 2021
- In situ Enzymatic Synthesis of Aptamer Targeted Polynucleotide Drug Nanoparticles for Cancer Therapy awarded by National Institutes of Health 2018 - 2021
- A Point-of-Injury Screening Assay for Tactical Damage Control Resuscitation awarded by United States Army Medical Research and Materiel Command 2017 - 2020
- Fully-printed electronic biosensors for the assessment of severe acute malnutrition awarded by National Institutes of Health 2018 - 2020
- Pharmacological Sciences Training Program awarded by National Institutes of Health 1975 - 2020
- Point of Care Testing to Improve Monitoring of LVAD Patients awarded by National Institutes of Health 2018 - 2020
- Exploration and Development of Glycoconjugation "Click" Cycloaddition of Azide Polysaccharide and Alkyne CRM197 awarded by Pfizer, Inc. 2017 - 2019
- Center for Environmental Implications of Nanotechnology awarded by National Science Foundation 2008 - 2019
- Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer awarded by National Institutes of Health 2018 - 2019
- Image-guided Dosimetry for Injectable Brachytherapy based on Elastin-like Polypeptide Nanoparticles awarded by National Institutes of Health 2017 - 2019
- A point-of-care, biomarker-based test to predict non-healing in chronic wounds awarded by The Plastic Surgery Foundation 2018 - 2019
- Collaborative Research: Supramolecular Materials by Nucleic Acid Block Copolymer Selfassembly awarded by National Science Foundation 2014 - 2019
- Delivery of Paclitaxel by Recombinant Polypeptide Nanoparticles awarded by Dr. Reddy's Laboratories Ltd. 2017 - 2019
- Smartphone Enabled Point-of-Care Detection of Serum Markers of Liver Cancer awarded by National Institutes of Health 2017 - 2019
- SO150005: Smartphone Enabled Point-of-care Diagnostics for Operationally Significant Pathogens awarded by United States Army Medical Research Acquisition Activity 2016 - 2019
- Self-assembled microporous networks for cell culture awarded by EMD Millipore 2017 - 2019
- OptiDiag: Optimizing diagnosis and management of acute malnutrition awarded by Action Contre La Faim 2015 - 2018
- Non-immunogenic PEG conjugates of Biologics awarded by North Carolina Biotechnology Center 2016 - 2018
- MRI: Acquisition of a Triple Quadrupole LC/MS System awarded by National Science Foundation 2015 - 2018
- Treating Melanoma with a Molecularly Engineered, Long Circulating Immunotoxin awarded by National Institutes of Health 2015 - 2018
- Elastin Fusion Proteins awarded by National Institutes of Health 2000 - 2018
- Delivery of Cis-Platinate by Recombinant Polypeptide Nanoparticles awarded by Dr. Reddy's Laboratories Ltd. 2017 - 2018
- Acquisition of a MALDI-TOF Mass Spectrometer System at Duke University awarded by North Carolina Biotechnology Center 2017 - 2018
- Assessing the Manufacturability of a "Next-Gen" Non-Immunogenic PEG-like Conjugate awarded by North Carolina Biotechnology Center 2016 - 2017
- One-Pot Synthesis of Multicomponent Protein-Carbohydrate Antigens awarded by Pfizer, Inc. 2016 - 2017
- Texas State University PREM: Center on Interfaces in Materials awarded by Texas State University 2012 - 2017
- Thermally Triggered Multivalent Targeting of Tumors awarded by National Institutes of Health 2007 - 2016
- Thermally Targeted Drug Delivery by Elastin Biopolymers awarded by National Institutes of Health 2002 - 2016
- Protease Operated Depot for Delivery of GLP-1 awarded by National Institutes of Health 2012 - 2016
- Site-specific antibody-toxin conjugates for cancer therapy awarded by National Institutes of Health 2015 - 2016
- Local Radionuclide Delivery to Solid Tumors by Injectible Biopolymer awarded by National Institutes of Health 2009 - 2016
- Site-Specific Growth of Stealth Polymer from Peptide Therapeutics awarded by National Institutes of Health 2011 - 2015
- Surface Initiated Enzymatic Polymerization of DNA Nanostructures for Highly Amplified Sensing awarded by National Science Foundation 2010 - 2015
- 2-D Diffusion Assay on Polymer Brush for POC Cardiac Infarction Diagnosis awarded by National Institutes of Health 2012 - 2015
- Live-Animal Micro-CT System awarded by National Institutes of Health 2012 - 2014
- SAXS System awarded by National Science Foundation 2012 - 2013
- Inhibition of metastasis-initiating cells by chimeric polypeptide nanoparticles awarded by National Institutes of Health 2010 - 2012
- Delivery of Peptide Therapeutics by Molecular Release Depots awarded by National Institutes of Health 2010 - 2012
- Detection of Biomolecules by Nanoscale Plasmon Ruler awarded by National Institutes of Health 2009 - 2012
- Genetically Designed Materials for Cartilage Repair awarded by National Institutes of Health 2003 - 2012
- Small Animal PET / CT Molecular Imaging awarded by National Institutes of Health 2011 - 2012
- Plasmonic assay for detection of biomarkers at the single-molecule level awarded by National Institutes of Health 2009 - 2011
- Intravital point-scanning confocal microscope awarded by National Institutes of Health 2010 - 2011
- Molecular Imaging Using Hyperspectral Darkfield Microscope of Nanoparticles awarded by National Science Foundation 2007 - 2011
- NIRT: Hierarchical Bionanomanufacturing awarded by National Science Foundation 2006 - 2010
- Thermally-Induced Intra-Articular Drug Delivery System awarded by National Institutes of Health 2006 - 2009
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Elastin Fusion Proteins awarded by National Institutes of Health 2000 - 2009
- Nanophotonics for Select Agent Detection awarded by Centers for Disease Control and Prevention 2003 - 2008
- Nanophotonics for Select Agent Detection awarded by Centers for Disease Control and Prevention 2003 - 2008
- Nanophotonics for Select Agent Detection awarded by Centers for Disease Control and Prevention 2003 - 2008
- NER: Integrated Magnetic and Chemical Assembly Techniques for Building Nanoparticle Arrays awarded by National Science Foundation 2006 - 2008
- pH Sensitive Elastic-Like-Peptides for Tumor Targeting awarded by National Institutes of Health 2006 - 2008
- Biointerface Science GRC awarded by Army Research Office 2006 - 2007
- Thermally Targeted Drug Delivery by Elastin Biopolymers awarded by National Institutes of Health 2002 - 2007
- NIRT awarded by National Science Foundation 2002 - 2006
- Upgrade of a Shared Instrumentation Resource in the PSOE: The Laser Scanning Confocal Microscope awarded by Lord Foundation of North Carolina 2002 - 2005
- Elastin Fusion Proteins awarded by National Institutes of Health 2000 - 2005
- The AVS2004 Biomaterials Interfaces Symposium awarded by National Institutes of Health 2004 - 2005
- Imaging XPS awarded by National Science Foundation 2002 - 2004
- Elastin Bioelastomers for Microactuation awarded by Office of Naval Research 2000 - 2002
- CAREER: Smart Protein-Polymer Conjugates for Biotechnology awarded by National Science Foundation 1998 - 2002
- (98-0048) CAREER: Smart Protein - Polymer Conjugates for Biotechnology awarded by National Science Foundation 1998 - 2002
- Engineered Protein-Polymer Conjugates for Biotechnology awarded by National Science Foundation 1998 - 2002
- Elastin Nanobiosensors awarded by National Science Foundation 2000 - 2002
- (97-0915) Extrinsic Modulation of Protein-Ligand Recognition awarded by National Institutes of Health 1998 - 2000
- Extrinsic Modulation of Protein/Ligand Recognition awarded by National Institutes of Health 1998 - 2000
- An Engineering Outreach Program for High School awarded by Lord Foundation of North Carolina 1998 - 1999
- Laboratories in Biomedical and Cellular Engineering awarded by Lord Foundation of North Carolina 1998 - 1999
- (98-0050) Isothermal Titration Calorimetry for Biological Research awarded by Division of Undergraduate Education 1998 - 1999
- (97-0056) Combined Atomic Force and Total Internal Reflection Fluorescence Microscopy for Biological Research awarded by National Science Foundation 1997 - 1999
- (97-0929) Matching Funds for Combined Atomic Force & Optical... awarded by Lord Foundation of North Carolina 1997 - 1998
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17, no. 12 (December 2018): 1154-1163. Full Text
  - Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Author Correction: Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17, no. 12 (December 2018): 1164-null. Full Text
  - Banskota, S, Yousefpour, P, Kirmani, N, Li, X, and Chilkoti, A. "Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery." Biomaterials 192 (November 28, 2018): 475-485. Full Text
  - Ruff, KM, Roberts, S, Chilkoti, A, and Pappu, RV. "Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers." Journal of Molecular Biology 430, no. 23 (November 2018): 4619-4635. (Review) Full Text
  - Fontes, CM, Achar, RK, Joh, DY, Ozer, I, Bhattacharjee, S, Hucknall, A, and Chilkoti, A. "Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays." Langmuir : the Acs Journal of Surfaces and Colloids (August 21, 2018). Full Text
  - Gu, R, Oweida, T, Yingling, YG, Chilkoti, A, and Zauscher, S. "Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation." Biomacromolecules (July 16, 2018). Full Text
  - Li, NK, Roberts, S, Quiroz, FG, Chilkoti, A, and Yingling, YG. "Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides." Biomacromolecules 19, no. 7 (July 2018): 2496-2505. Full Text
  - Dzuricky, M, Roberts, S, and Chilkoti, A. "Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins." Biochemistry 57, no. 17 (May 2018): 2405-2414. Full Text
  - Gilroy, CA, Roberts, S, and Chilkoti, A. "Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action." Journal of Controlled Release : Official Journal of the Controlled Release Society 277 (May 2018): 154-164. Full Text
  - Mozhdehi, D, Luginbuhl, KM, Simon, JR, Dzuricky, M, Berger, R, Varol, HS, Huang, FC, Buehne, KL, Mayne, NR, Weitzhandler, I, Bonn, M, Parekh, SH, and Chilkoti, A. "Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly." Nature Chemistry 10, no. 5 (May 2018): 496-505. Full Text
  - Costa, SA, Simon, JR, Amiram, M, Tang, L, Zauscher, S, Brustad, EM, Isaacs, FJ, and Chilkoti, A. "Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides." Advanced materials (Deerfield Beach, Fla.) 30, no. 5 (February 2018). Full Text
  - Li, L, Li, NK, Tu, Q, Im, O, Mo, C-K, Han, W, Fuss, WH, Carroll, NJ, Chilkoti, A, Yingling, YG, Zauscher, S, and López, GP. "Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers." Biomacromolecules 19, no. 2 (February 2018): 298-306. Full Text
  - Mastria, EM, Cai, LY, Kan, MJ, Li, X, Schaal, JL, Fiering, S, Gunn, MD, Dewhirst, MW, Nair, SK, and Chilkoti, A. "Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity." Journal of Controlled Release : Official Journal of the Controlled Release Society 269 (January 2018): 364-373. Full Text
  - Luginbuhl, KM, Mozhdehi, D, Dzuricky, M, Yousefpour, P, Huang, FC, Mayne, NR, Buehne, KL, and Chilkoti, A. "Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs." Angewandte Chemie (International ed. in English) 56, no. 45 (November 2017): 13979-13984. Full Text
  - Wang, J, Dzuricky, M, and Chilkoti, A. "The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles." Nano Letters 17, no. 10 (October 2017): 5995-6005. Full Text
  - Joh, DY, Hucknall, AM, Wei, Q, Mason, KA, Lund, ML, Fontes, CM, Hill, RT, Blair, R, Zimmers, Z, Achar, RK, Tseng, D, Gordan, R, Freemark, M, Ozcan, A, and Chilkoti, A. "Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood." Proceedings of the National Academy of Sciences of the United States of America 114, no. 34 (August 7, 2017): E7054-E7062. Full Text
  - Bhattacharyya, J, Ren, X-R, Mook, RA, Wang, J, Spasojevic, I, Premont, RT, Li, X, Chilkoti, A, and Chen, W. "Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth." Nanoscale 9, no. 34 (August 2017): 12709-12717. Full Text
  - Wang, J, Bhattacharyya, J, Mastria, E, and Chilkoti, A. "A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles." Journal of Controlled Release : Official Journal of the Controlled Release Society 260 (August 2017): 100-110. Full Text
  - Weitzhandler, I, Dzuricky, M, Hoffmann, I, Garcia Quiroz, F, Gradzielski, M, and Chilkoti, A. "Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides." Biomacromolecules 18, no. 8 (August 2017): 2419-2426. Full Text
  - MacEwan, SR, and Chilkoti, A. "From Composition to Cure: A Systems Engineering Approach to Anticancer Drug Carriers." Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6712-6733. (Review) Full Text
  - Simon, JR, Carroll, NJ, Rubinstein, M, Chilkoti, A, and López, GP. "Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity." Nature Chemistry 9, no. 6 (June 2017): 509-515. Full Text
  - Tang, L, Navarro, LA, Chilkoti, A, and Zauscher, S. "High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation." Angewandte Chemie (International Ed. in English) 56, no. 24 (June 2017): 6778-6782. Full Text
  - Han, W, Chilkoti, A, and López, GP. "Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release." Nanoscale 9, no. 18 (May 2017): 6178-6186. Full Text
  - Weinberger, A, Walter, V, MacEwan, SR, Schmatko, T, Muller, P, Schroder, AP, Chilkoti, A, and Marques, CM. "Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes." Scientific Reports 7 (March 6, 2017). Full Text
  - Bhattacharyya, J, Weitzhandler, I, Ho, SB, McDaniel, JR, Li, X, Tang, L, Liu, J, Dewhirst, M, and Chilkoti, A. "Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy." Advanced Functional Materials 27, no. 12 (March 2017). Full Text
  - Gonzalez, MA, Simon, JR, Ghoorchian, A, Scholl, Z, Lin, S, Rubinstein, M, Marszalek, P, Chilkoti, A, López, GP, and Zhao, X. "Strong, Tough, Stretchable, and Self-Adhesive Hydrogels from Intrinsically Unstructured Proteins." Advanced Materials (Deerfield Beach, Fla.) 29, no. 10 (March 2017). Full Text
  - Ozer, I, and Chilkoti, A. "Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins." Bioconjugate Chemistry 28, no. 3 (March 2017): 713-723. (Review) Full Text
  - Widder, K, MacEwan, SR, Garanger, E, Núñez, V, Lecommandoux, S, Chilkoti, A, and Hinderberger, D. "Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers." Soft matter 13, no. 9 (March 2017): 1816-1822. Full Text
  - Joh, DY, McGuire, F, Abedini-Nassab, R, Andrews, JB, Achar, RK, Zimmers, Z, Mozhdehi, D, Blair, R, Albarghouthi, F, Oles, W, Richter, J, Fontes, CM, Hucknall, AM, Yellen, BB, Franklin, AD, and Chilkoti, A. "Poly(oligo(ethylene glycol) methyl ether methacrylate) Brushes on High-κ Metal Oxide Dielectric Surfaces for Bioelectrical Environments." ACS applied materials & interfaces 9, no. 6 (February 2017): 5522-5529. Full Text
  - MacEwan, SR, Weitzhandler, I, Hoffmann, I, Genzer, J, Gradzielski, M, and Chilkoti, A. "Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides." Biomacromolecules 18, no. 2 (February 2017): 599-609. Full Text
  - Wang, J, MacEwan, SR, and Chilkoti, A. "Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH." Nano Letters 17, no. 2 (February 2017): 1226-1232. Full Text
  - Banskota, S, Yousefpour, P, and Chilkoti, A. "Cell-Based Biohybrid Drug Delivery Systems: The Best of the Synthetic and Natural Worlds." Macromolecular bioscience 17, no. 1 (January 2017). (Review) Full Text
  - Luginbuhl, KM, Schaal, JL, Umstead, B, Mastria, EM, Li, X, Banskota, S, Arnold, S, Feinglos, M, D'Alessio, D, and Chilkoti, A. "One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer." Nature Biomedical Engineering 1 (January 2017). Full Text
  - Kwok, KWH, Dong, W, Marinakos, SM, Liu, J, Chilkoti, A, Wiesner, MR, Chernick, M, and Hinton, DE. "Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation." Nanotoxicology 10, no. 9 (November 2016): 1306-1317. Full Text Open Access Copy
  - Abedini-Nassab, R, Joh, DY, Albarghouthi, F, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Magnetophoretic transistors in a tri-axial magnetic field." Lab on a Chip 16, no. 21 (October 2016): 4181-4188. Full Text
  - Gilroy, CA, Luginbuhl, KM, and Chilkoti, A. "Controlled release of biologics for the treatment of type 2 diabetes." Journal of Controlled Release : Official Journal of the Controlled Release Society 240 (October 2016): 151-164. (Review) Full Text
  - Pham, AT, Seto, R, Schönke, J, Joh, DY, Chilkoti, A, Fried, E, and Yellen, BB. "Crystallization kinetics of binary colloidal monolayers." Soft Matter 12, no. 37 (October 2016): 7735-7746. Full Text
  - Liu, J, Pang, Y, Bhattacharyya, J, Liu, W, Weitzhandler, I, Li, X, and Chilkoti, A. "Developing Precisely Defined Drug-Loaded Nanoparticles by Ring-Opening Polymerization of a Paclitaxel Prodrug." Advanced healthcare materials 5, no. 15 (August 2016): 1868-1873. Full Text
  - Pang, Y, Liu, J, Qi, Y, Li, X, and Chilkoti, A. "A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics." Angewandte Chemie (International Ed. in English) 55, no. 35 (August 2016): 10296-10300. Full Text
  - Li, L, Mo, C-K, Chilkoti, A, Lopez, GP, and Carroll, NJ. "Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides." Biointerphases 11, no. 2 (June 27, 2016): 021009-. Full Text
  - Abedini-Nassab, R, Joh, DY, Van Heest, M, Baker, C, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Magnetophoretic Conductors and Diodes in a 3D Magnetic Field." Advanced Functional Materials 26, no. 22 (June 2016): 4026-4034. Full Text
  - Schaal, JL, Li, X, Mastria, E, Bhattacharyya, J, Zalutsky, MR, Chilkoti, A, and Liu, W. "Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy." Journal of controlled release : official journal of the Controlled Release Society 228 (April 2016): 58-66. Full Text
  - Tang, NC, and Chilkoti, A. "Combinatorial codon scrambling enables scalable gene synthesis and amplification of repetitive proteins." Nature materials 15, no. 4 (April 2016): 419-424. Full Text
  - Nawroth, JF, McDaniel, JR, Chilkoti, A, Jordan, R, and Luxenhofer, R. "Maleimide-Functionalized Poly(2-Oxazoline)s and Their Conjugation to Elastin-Like Polypeptides." Macromolecular bioscience 16, no. 3 (March 2016): 322-333. Full Text
  - Mukerji, R, Schaal, J, Li, X, Bhattacharyya, J, Asai, D, Zalutsky, MR, Chilkoti, A, and Liu, W. "Spatiotemporally photoradiation-controlled intratumoral depot for combination of brachytherapy and photodynamic therapy for solid tumor." Biomaterials 79 (February 2016): 79-87. Full Text
  - Qi, Y, Simakova, A, Ganson, NJ, Li, X, Luginbuhl, KM, Özer, I, Liu, W, Hershfield, MS, Matyjaszewski, K, and Chilkoti, A. "A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity." Nature Biomedical Engineering 1 (January 2016). Full Text
  - Bhattacharjee, S, Liu, W, Wang, W-H, Weitzhandler, I, Li, X, Qi, Y, Liu, J, Pang, Y, Hunt, DF, and Chilkoti, A. "Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation." Chembiochem : a European Journal of Chemical Biology 16, no. 17 (November 2015): 2451-2455. Full Text
  - Li, NK, Fuss, WH, Tang, L, Gu, R, Chilkoti, A, Zauscher, S, and Yingling, YG. "Prediction of solvent-induced morphological changes of polyelectrolyte diblock copolymer micelles." Soft matter 11, no. 42 (November 2015): 8236-8245. Full Text
  - Quiroz, FG, and Chilkoti, A. "Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers." Nature Materials 14, no. 11 (November 2015): 1164-1171. Full Text
  - Abedini-Nassab, R, Joh, DY, Van Heest, MA, Yi, JS, Baker, C, Taherifard, Z, Margolis, DM, Garcia, JV, Chilkoti, A, Murdoch, DM, and Yellen, BB. "Characterizing the Switching Thresholds of Magnetophoretic Transistors." Advanced materials (Deerfield Beach, Fla.) 27, no. 40 (October 2015): 6176-6180. Full Text Open Access Copy
  - Qi, Y, and Chilkoti, A. "Protein-polymer conjugation-moving beyond PEGylation." Current Opinion in Chemical Biology 28 (October 2015): 181-193. (Review) Full Text
  - Garanger, E, MacEwan, SR, Sandre, O, Brûlet, A, Bataille, L, Chilkoti, A, and Lecommandoux, S. "Structural Evolution of a Stimulus-Responsive Diblock Polypeptide Micelle by Temperature Tunable Compaction of its Core." Macromolecules 48, no. 18 (September 22, 2015): 6617-6627. Full Text
  - Roberts, S, Dzuricky, M, and Chilkoti, A. "Elastin-like polypeptides as models of intrinsically disordered proteins." Febs Letters 589, no. 19 Pt A (September 2015): 2477-2486. (Review) Full Text
  - Bhattacharyya, J, Bellucci, JJ, Weitzhandler, I, McDaniel, JR, Spasojevic, I, Li, X, Lin, C-C, Chi, J-TA, and Chilkoti, A. "A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models." Nature Communications 6 (August 4, 2015): 7939-null. Full Text
  - Han, W, MacEwan, SR, Chilkoti, A, and López, GP. "Bio-inspired synthesis of hybrid silica nanoparticles templated from elastin-like polypeptide micelles." Nanoscale 7, no. 28 (July 2015): 12038-12044. Full Text
  - Hassouneh, W, Zhulina, EB, Chilkoti, A, and Rubinstein, M. "Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles." Macromolecules 48, no. 12 (June 11, 2015): 4183-4195. Full Text
  - Ghoorchian, A, Simon, JR, Bharti, B, Han, W, Zhao, X, Chilkoti, A, and López, GP. "Bioinspired Reversibly Cross-linked Hydrogels Comprising Polypeptide Micelles Exhibit Enhanced Mechanical Properties." Advanced Functional Materials 25, no. 21 (June 2015): 3122-3130. Full Text
  - Ghoorchian, A, Simon, JR, Bharti, B, Han, W, Zhao, X, Chilkoti, A, and Lõpez, GP. "Bioinspired reversibly cross-linked hydrogels comprising polypeptide micelles exhibit enhanced mechanical properties." Advanced Functional Materials 25, no. 21 (June 1, 2015): 3122-3130. Full Text
  - Mastria, EM, Chen, M, McDaniel, JR, Li, X, Hyun, J, Dewhirst, MW, and Chilkoti, A. "Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma." Journal of Controlled Release : Official Journal of the Controlled Release Society 208 (June 2015): 52-58. Full Text
  - Kimmerling, KA, Furman, BD, Mangiapani, DS, Moverman, MA, Sinclair, SM, Huebner, JL, Chilkoti, A, Kraus, VB, Setton, LA, Guilak, F, and Olson, SA. "Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis." European Cells & Materials 29 (January 31, 2015): 124-139.
  - Bellucci, JJ, Bhattacharyya, J, and Chilkoti, A. "A noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteins." Angewandte Chemie (International Ed. in English) 54, no. 2 (January 2015): 441-445. Full Text
  - Liu, J, Liu, W, Weitzhandler, I, Bhattacharyya, J, Li, X, Wang, J, Qi, Y, Bhattacharjee, S, and Chilkoti, A. "Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles." Angewandte Chemie (International ed. in English) 54, no. 3 (January 2015): 1002-1006. Full Text
  - McDaniel, JR, Weitzhandler, I, Prevost, S, Vargo, KB, Appavou, M-S, Hammer, DA, Gradzielski, M, and Chilkoti, A. "Noncanonical self-assembly of highly asymmetric genetically encoded polypeptide amphiphiles into cylindrical micelles." Nano letters 14, no. 11 (November 2014): 6590-6598. Full Text
  - Hill, RT, Kozek, KM, Hucknall, A, Smith, DR, and Chilkoti, A. "Nanoparticle-Film Plasmon Ruler Interrogated with Transmission Visible Spectroscopy." ACS photonics 1, no. 10 (October 2014): 974-984. Full Text
  - Li, NK, García Quiroz, F, Hall, CK, Chilkoti, A, and Yingling, YG. "Molecular description of the LCST behavior of an elastin-like polypeptide." Biomacromolecules 15, no. 10 (October 2014): 3522-3530. Full Text
  - Macewan, SR, and Chilkoti, A. "Applications of elastin-like polypeptides in drug delivery." Journal of Controlled Release 190 (September 28, 2014): 314-330. Full Text
  - MacEwan, SR, and Chilkoti, A. "Applications of elastin-like polypeptides in drug delivery." Journal of controlled release : official journal of the Controlled Release Society 190 (September 2014): 314-330. (Review) Full Text
  - Yousefpour, P, and Chilkoti, A. "Co-opting biology to deliver drugs." Biotechnology and bioengineering 111, no. 9 (September 2014): 1699-1716. (Review) Full Text
  - MacEwan, SR, Hassouneh, W, and Chilkoti, A. "Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli." Journal of visualized experiments : JoVE , no. 88 (June 9, 2014). Full Text
  - Ghoorchian, A, Chilkoti, A, and López, GP. "Simple assay for proteases based on aggregation of stimulus-responsive polypeptides." Analytical chemistry 86, no. 12 (June 2014): 6103-6110. Full Text
  - Tang, L, Tjong, V, Li, N, Yingling, YG, Chilkoti, A, and Zauscher, S. "Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles." Advanced Materials 26, no. 19 (May 21, 2014): 3050-3054. Full Text
  - McDaniel, JR, MacEwan, SR, Li, X, Radford, DC, Landon, CD, Dewhirst, M, and Chilkoti, A. "Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors." Nano letters 14, no. 5 (May 2014): 2890-2895. Full Text
  - Tang, L, Tjong, V, Li, N, Yingling, YG, Chilkoti, A, and Zauscher, S. "Enzymatic polymerization of high molecular weight DNA amphiphiles that self-assemble into star-like micelles." Advanced materials (Deerfield Beach, Fla.) 26, no. 19 (May 2014): 3050-3054. Full Text
  - Tjong, V, Tang, L, Zauscher, S, and Chilkoti, A. ""Smart" DNA interfaces." Chemical Society Reviews 43, no. 5 (March 2014): 1612-1626. (Review) Full Text
  - Qi, Y, and Chilkoti, A. "Growing polymers from peptides and proteins: A biomedical perspective." Polymer Chemistry 5, no. 2 (January 21, 2014): 266-276. Full Text
  - MacEwan, SR, Hassouneh, W, and Chilkoti, A. "Non-chromatographic purification of recombinant elastin-like polypeptides and their fusions with peptides and proteins from Escherichia coli." Journal of visualized experiments : JoVE , no. 88 (January 1, 2014).
  - MacEwan, SR, and Chilkoti, A. "Controlled apoptosis by a thermally toggled nanoscale amplifier of cellular uptake." Nano letters 14, no. 4 (January 2014): 2058-2064. Full Text
  - Mastria, E, and Chilkoti, A. "Genetically encoded “smart” peptide polymers for biomedicine." MRS Bulletin 39, no. 01 (January 2014): 35-43. Full Text
  - Yousefpour, P, and Chilkoti, A. "Co-opting biology to deliver drugs." Biotechnology and Bioengineering 111, no. 9 (2014): 1699-1716. Full Text
  - Qi, Y, Amiram, M, Gao, W, and Chilkoti, A. "Sortase-mediated initiator attachment for in situ grafting of a PEG-based polymer brush from the C terminus of green fluorescent protein." J Control Release 172, no. 1 (November 28, 2013): e121-null. Full Text Link to Item
  - Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection." Journal of Controlled Release : Official Journal of the Controlled Release Society 172, no. 1 (November 2013): 144-151. Full Text
  - Sinclair, SM, Bhattacharyya, J, McDaniel, JR, Gooden, DM, Gopalaswamy, R, Chilkoti, A, and Setton, LA. "A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation." Journal of Controlled Release : Official Journal of the Controlled Release Society 171, no. 1 (October 2013): 38-47. Full Text Open Access Copy
  - McDaniel, JR, Dewhirst, MW, and Chilkoti, A. "Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia." Int J Hyperthermia 29, no. 6 (September 2013): 501-510. (Review) Full Text Link to Item
  - Khan, MN, Tjong, V, Chilkoti, A, and Zharnikov, M. "Spectroscopic study of a DNA brush synthesized in situ by surface initiated enzymatic polymerization." The Journal of Physical Chemistry. B 117, no. 34 (August 15, 2013): 9929-9938. Full Text
  - McDaniel, JR, Radford, DC, and Chilkoti, A. "A unified model for de novo design of elastin-like polypeptides with tunable inverse transition temperatures." Biomacromolecules 14, no. 8 (August 2013): 2866-2872. Full Text
  - Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein." Macromolecular Rapid Communications 34, no. 15 (August 2013): 1256-1260. Full Text
  - Kurzbach, D, Hassouneh, W, McDaniel, JR, Jaumann, EA, Chilkoti, A, and Hinderberger, D. "Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers." J Am Chem Soc 135, no. 30 (July 31, 2013): 11299-11308. Full Text Link to Item
  - Hassouneh, W, Nunalee, ML, Shelton, MC, and Chilkoti, A. "Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides." Biomacromolecules 14, no. 7 (July 2013): 2347-2353. Full Text
  - Weller, D, McDaniel, JR, Fischer, K, Chilkoti, A, and Schmidt, M. "Cylindrical Polymer Brushes with Elastin-Like Polypeptide Side Chains." Macromolecules 46, no. 12 (June 25, 2013): 4966-4971. Full Text
  - Christensen, T, Hassouneh, W, Trabbic-Carlson, K, and Chilkoti, A. "Predicting transition temperatures of elastin-like polypeptide fusion proteins." Biomacromolecules 14, no. 5 (May 2013): 1514-1519. Full Text
  - Bellucci, JJ, Amiram, M, Bhattacharyya, J, McCafferty, D, and Chilkoti, A. "Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides." Angew Chem Int Ed Engl 52, no. 13 (March 25, 2013): 3703-3708. Full Text Link to Item
  - Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control." Proceedings of the National Academy of Sciences of the United States of America 110, no. 8 (February 2013): 2792-2797. Full Text
  - McDaniel, JR, Bhattacharyya, J, Vargo, KB, Hassouneh, W, Hammer, DA, and Chilkoti, A. "Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation." Angewandte Chemie (International Ed. in English) 52, no. 6 (February 2013): 1683-1687. Full Text
  - Lassiter, JB, McGuire, F, Mock, JJ, Ciracì, C, Hill, RT, Wiley, BJ, Chilkoti, A, and Smith, DR. "Plasmonic waveguide modes of film-coupled metallic nanocubes." Nano Letters 13, no. 12 (January 2013): 5866-5872. Full Text
  - Li, L, Im, O, Chilkoti, A, and López, GP. "Encapsulation of Stimuli-Responsive Fusion Proteins in Silica: Thermally Responsive Metal Ion-Sensitive Hybrid Membranes." MRS Proceedings 1498 (January 2013). Full Text
  - MacEwan, SR, and Chilkoti, A. "Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents." Wiley Interdiscip Rev Nanomed Nanobiotechnol 5, no. 1 (January 2013): 31-48. (Review) Full Text Link to Item
  - Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-Catalyzed Initiator Attachment Enables High Yield Growth of a Stealth Polymer from the C Terminus of a Protein." Macromolecular Rapid Communications 34, no. 15 (2013): 1256-1260. Full Text
  - Thapa, A, Han, W, Simons, RH, Chilkoti, A, Chi, EY, and López, GP. "Effect of detergents on the thermal behavior of elastin-like polypeptides." Biopolymers 99, no. 1 (January 2013): 55-62. Full Text Link to Item
  - Tjong, V, Yu, H, Hucknall, A, and Chilkoti, A. "Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization." Analytical Chemistry 85, no. 1 (January 2013): 426-433. Full Text
  - Tjong, V, Yu, H, Hucknall, A, and Chilkoti, A. "Amplified fluorescence detection of DNA and RNA hybridization by surface initiated enzymatic polymerization (SIEP)." Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013 3 (2013): 32-36.
  - Moreau, A, Ciracì, C, Mock, JJ, Hill, RT, Wang, Q, Wiley, BJ, Chilkoti, A, and Smith, DR. "Controlled-reflectance surfaces with film-coupled colloidal nanoantennas." Nature 492, no. 7427 (December 2012): 86-89. Full Text
  - Liu, W, McDaniel, J, Li, X, Asai, D, Quiroz, FG, Schaal, J, Park, JS, Zalutsky, M, and Chilkoti, A. "Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ." Cancer Research 72, no. 22 (November 2012): 5956-5965. Full Text
  - Manzoor, AA, Lindner, LH, Landon, CD, Park, J-Y, Simnick, AJ, Dreher, MR, Das, S, Hanna, G, Park, W, Chilkoti, A, Koning, GA, ten Hagen, TLM, Needham, D, and Dewhirst, MW. "Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors." Cancer Research 72, no. 21 (November 2012): 5566-5575. Full Text
  - Hill, RT, Mock, JJ, Hucknall, A, Wolter, SD, Jokerst, NM, Smith, DR, and Chilkoti, A. "Plasmon ruler with angstrom length resolution." ACS Nano 6, no. 10 (October 23, 2012): 9237-9246. Full Text Link to Item
  - Khan, MN, Tjong, V, Chilkoti, A, and Zharnikov, M. "Fabrication of ssDNA/oligo(ethylene glycol) monolayers and complex nanostructures by an irradiation-promoted exchange reaction." Angewandte Chemie (International Ed. in English) 51, no. 41 (October 2012): 10303-10306. Full Text
  - Kwok, KWH, Auffan, M, Badireddy, AR, Nelson, CM, Wiesner, MR, Chilkoti, A, Liu, J, Marinakos, SM, and Hinton, DE. "Uptake of silver nanoparticles and toxicity to early life stages of Japanese medaka (Oryzias latipes): effect of coating materials." Aquat Toxicol 120-121 (September 15, 2012): 59-66. Full Text Link to Item
  - Ciracì, C, Hill, RT, Mock, JJ, Urzhumov, Y, Fernández-Domínguez, AI, Maier, SA, Pendry, JB, Chilkoti, A, and Smith, DR. "Probing the ultimate limits of plasmonic enhancement." Science (New York, N.Y.) 337, no. 6098 (August 2012): 1072-1074. Full Text Open Access Copy
  - Xu, D, Asai, D, Chilkoti, A, and Craig, SL. "Rheological properties of cysteine-containing elastin-like polypeptide solutions and hydrogels." Biomacromolecules 13, no. 8 (August 2012): 2315-2321. Full Text
  - Asai, D, Xu, D, Liu, W, Garcia Quiroz, F, Callahan, DJ, Zalutsky, MR, Craig, SL, and Chilkoti, A. "Protein polymer hydrogels by in situ, rapid and reversible self-gelation." Biomaterials 33, no. 21 (July 2012): 5451-5458. Full Text Link to Item
  - Hubbell, JA, and Chilkoti, A. "Chemistry. Nanomaterials for drug delivery." Science (New York, N.Y.) 337, no. 6092 (July 2012): 303-305. Full Text
  - Macewan, SR, and Chilkoti, A. "Digital switching of local arginine density in a genetically encoded self-assembled polypeptide nanoparticle controls cellular uptake." Nano Lett 12, no. 6 (June 13, 2012): 3322-3328. Full Text Link to Item
  - Hassouneh, W, Fischer, K, MacEwan, SR, Branscheid, R, Fu, CL, Liu, R, Schmidt, M, and Chilkoti, A. "Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers." Biomacromolecules 13, no. 5 (May 2012): 1598-1605. Full Text
  - McDaniel, JR, Macewan, SR, Dewhirst, M, and Chilkoti, A. "Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia." Journal of Controlled Release : Official Journal of the Controlled Release Society 159, no. 3 (May 2012): 362-367. Full Text
  - Callahan, DJ, Liu, W, Li, X, Dreher, MR, Hassouneh, W, Kim, M, Marszalek, P, and Chilkoti, A. "Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution." Nano Letters 12, no. 4 (April 2012): 2165-2170. Full Text
  - Mock, JJ, Hill, RT, Tsai, Y-J, Chilkoti, A, and Smith, DR. "Probing dynamically tunable localized surface plasmon resonances of film-coupled nanoparticles by evanescent wave excitation." Nano Letters 12, no. 4 (April 2012): 1757-1764. Full Text
  - Tjong, V, Zhang, J, Chilkoti, A, and Zauscher, S. "Stimulus-Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications." (February 3, 2012): 1-30. (Chapter) Full Text
  - Christensen, T, Hassouneh, W, Callahan, DJ, and Chilkoti, A. "Protein switches." Comprehensive Biophysics 3 (2012): 238-266. Full Text
  - Hassouneh, W, MacEwan, SR, and Chilkoti, A. "Fusions of elastin-like polypeptides to pharmaceutical proteins." Methods in Enzymology 502 (January 2012): 215-237. Full Text
  - Chen, SY, Mock, JJ, Hill, RT, Chilkoti, A, Smith, DR, and Lazarides, AA. "Raman antenna formed by molecule/plasmonic nanostructure hybrid system." Optics InfoBase Conference Papers (December 1, 2011).
  - Ferris, R, Hucknall, A, Kwon, BS, Chen, T, Chilkoti, A, and Zauscher, S. "Field-induced nanolithography for patterning of non-fouling polymer brush surfaces." Small (Weinheim an Der Bergstrasse, Germany) 7, no. 21 (November 2011): 3032-3037. Full Text
  - Seekell, K, Crow, MJ, Marinakos, S, Ostrander, J, Chilkoti, A, and Wax, A. "Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles." Journal of Biomedical Optics 16, no. 11 (November 2011): 116003-null. Full Text
  - Simnick, AJ, Amiram, M, Liu, W, Hanna, G, Dewhirst, MW, Kontos, CD, and Chilkoti, A. "In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide." Journal of Controlled Release : Official Journal of the Controlled Release Society 155, no. 2 (October 2011): 144-151. Full Text
  - Nusz, GJ, Marinakos, SM, Rangarajan, S, and Chilkoti, A. "Dual-order snapshot spectral imaging of plasmonic nanoparticles." Appl Opt 50, no. 21 (July 20, 2011): 4198-4206. Link to Item
  - Tjong, V, Yu, H, Hucknall, A, Rangarajan, S, and Chilkoti, A. "Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization." Analytical Chemistry 83, no. 13 (July 2011): 5153-5159. Full Text
  - Fluegel, S, Buehler, J, Fischer, K, McDaniel, JR, Chilkoti, A, and Schmidt, M. "Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles." Chemistry 17, no. 20 (May 9, 2011): 5503-5506. Full Text Link to Item
  - Ahmad, SA, Leggett, GJ, Hucknall, A, and Chilkoti, A. "Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization." Biointerphases 6, no. 1 (March 2011): 8-15. Full Text Link to Item
  - Yang, P, Marinakos, SM, and Chilkoti, A. "Spatially addressable chemoselective C-terminal ligation of an intein fusion protein from a complex mixture to a hydrazine-terminated surface." Langmuir 27, no. 4 (February 15, 2011): 1463-1471. Full Text Link to Item
  - Amiram, M, Quiroz, FG, Callahan, DJ, and Chilkoti, A. "A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers." Nat Mater 10, no. 2 (February 2011): 141-148. Full Text Link to Item
  - Ahmad, SA, Leggett, GJ, Hucknall, A, and Chilkoti, A. "Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization." Biointerphases 6, no. 1 (2011): 8-15. Full Text
  - Chen, M, McDaniel, JR, Mackay, JA, and Chilkoti, A. "NANOSCALE SELF-ASSEMBLY FOR DELIVERY OF THERAPEUTICS AND IMAGING AGENTS." Technology and Innovation 13, no. 1 (January 2011): 5-25. Full Text
  - Chen, S-Y, Mock, JJ, Hill, RT, Chilkoti, A, Smith, DR, and Lazarides, AA. "Raman antenna formed by molecule/plasmonic nanostructure hybrid system." 2011 Conference on Lasers and Electro-Optics: Laser Science to Photonic Applications, CLEO 2011 (2011).
  - Crow, MJ, Marinakos, SM, Cook, JM, Chilkoti, A, and Wax, A. "Plasmonic flow cytometry by immunolabeled nanorods." Cytometry A 79, no. 1 (January 2011): 57-65. Full Text Link to Item
  - Crow, MJ, Seekell, K, Marinakos, S, Ostrander, J, Chilkoti, A, and Wax, AP. "Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 7911 (2011). Full Text
  - Gao, W, Xu, D, Lim, DW, Craig, SL, and Chilkoti, A. "In situ growth of a thermoresponsive polymer from a genetically engineered elastin-like polypeptide." Polymer Chemistry 2, no. 7 (2011): 1561-1566. Full Text
  - Williams, C, Brown, XQ, Bartolak-Suki, E, Ma, H, Chilkoti, A, and Wong, JY. "The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells." Biomaterials 32, no. 2 (January 2011): 410-418. Full Text Link to Item
  - McDaniel, JR, Callahan, DJ, and Chilkoti, A. "Drug delivery to solid tumors by elastin-like polypeptides." Advanced Drug Delivery Reviews 62, no. 15 (December 2010): 1456-1467. (Review) Full Text
  - Nettles, DL, Chilkoti, A, and Setton, LA. "Applications of elastin-like polypeptides in tissue engineering." Advanced Drug Delivery Reviews 62, no. 15 (December 2010): 1479-1485. (Review) Full Text
  - Fluegel, S, Fischer, K, McDaniel, JR, Chilkoti, A, and Schmidt, M. "Chain stiffness of elastin-like polypeptides." Biomacromolecules 11, no. 11 (November 8, 2010): 3216-3218. Full Text Open Access Copy Link to Item
  - Mackay, JA, Callahan, DJ, Fitzgerald, KN, and Chilkoti, A. "Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides." Biomacromolecules 11, no. 11 (November 8, 2010): 2873-2879. Full Text Open Access Copy Link to Item
  - Chen, S-Y, Mock, JJ, Hill, RT, Chilkoti, A, Smith, DR, and Lazarides, AA. "Gold nanoparticles on polarizable surfaces as Raman scattering antennas." Acs Nano 4, no. 11 (November 2010): 6535-6546. Full Text Open Access Copy
  - Hill, RT, Mock, JJ, Urzhumov, Y, Sebba, DS, Oldenburg, SJ, Chen, S-Y, Lazarides, AA, Chilkoti, A, and Smith, DR. "Leveraging nanoscale plasmonic modes to achieve reproducible enhancement of light." Nano Lett 10, no. 10 (October 13, 2010): 4150-4154. Full Text Open Access Copy Link to Item
  - Meyer, JN, Lord, CA, Yang, XY, Turner, EA, Badireddy, AR, Marinakos, SM, Chilkoti, A, Wiesner, MR, and Auffan, M. "Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans." Aquatic Toxicology (Amsterdam, Netherlands) 100, no. 2 (October 2010): 140-150. Full Text
  - Gao, W, Liu, W, Christensen, T, Zalutsky, MR, and Chilkoti, A. "In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation." Proceedings of the National Academy of Sciences of the United States of America 107, no. 38 (September 2010): 16432-16437. Full Text
  - Hassouneh, W, Christensen, T, and Chilkoti, A. "Elastin-like polypeptides as a purification tag for recombinant proteins." Current Protocols in Protein Science Chapter 6 (August 2010): Unit-6.11. Full Text
  - MacEwan, SR, Callahan, DJ, and Chilkoti, A. "Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery." Nanomedicine (London, England) 5, no. 5 (July 2010): 793-806. (Review) Full Text
  - Alang Ahmad, S, Hucknall, A, Chilkoti, A, and Leggett, GJ. "Protein patterning by UV-induced photodegradation of poly(oligo(ethylene glycol) methacrylate) brushes." Langmuir : the Acs Journal of Surfaces and Colloids 26, no. 12 (June 2010): 9937-9942. Full Text Open Access Copy
  - Liu, W, MacKay, JA, Dreher, MR, Chen, M, McDaniel, JR, Simnick, AJ, Callahan, DJ, Zalutsky, MR, and Chilkoti, A. "Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model." J Control Release 144, no. 1 (May 21, 2010): 2-9. Full Text Link to Item
  - Jenness, NJ, Hill, RT, Hucknall, A, Chilkoti, A, and Clark, RL. "A versatile diffractive maskless lithography for single-shot and serial microfabrication." Optics Express 18, no. 11 (May 2010): 11754-11762. Full Text Open Access Copy
  - McDaniel, JR, Mackay, JA, Quiroz, FG, and Chilkoti, A. "Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes." Biomacromolecules 11, no. 4 (April 12, 2010): 944-952. Full Text Open Access Copy Link to Item
  - Simnick, AJ, Valencia, CA, Liu, R, and Chilkoti, A. "Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer." Acs Nano 4, no. 4 (April 2010): 2217-2227. Full Text Open Access Copy
  - MacEwan, SR, and Chilkoti, A. "Elastin-like polypeptides: biomedical applications of tunable biopolymers." Biopolymers 94, no. 1 (January 2010): 60-77. (Review) Full Text
  - Nettles, DL, Haider, MA, Chilkoti, A, and Setton, LA. "Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds." Tissue Eng Part A 16, no. 1 (January 2010): 11-20. Full Text Open Access Copy Link to Item
  - MacKay, JA, Chen, M, McDaniel, JR, Liu, W, Simnick, AJ, and Chilkoti, A. "Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection." Nature Materials 8, no. 12 (December 2009): 993-999. Full Text
  - MacKay, JA, Chen, M, McDaniel, JR, Liu, W, Simnick, AJ, and Chilkoti, A. "Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection." NATURE MATERIALS 8, no. 12 (December 2009): 993-999. Full Text Link to Item
  - Cho, Y, Sagle, LB, Iimura, S, Zhang, Y, Kherb, J, Chilkoti, A, Scholtz, JM, and Cremer, PS. "Hydrogen bonding of beta-turn structure is stabilized in D(2)O." J Am Chem Soc 131, no. 42 (October 28, 2009): 15188-15193. Full Text Link to Item
  - Gao, W, Liu, W, Mackay, JA, Zalutsky, MR, Toone, EJ, and Chilkoti, A. "In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics." Proceedings of the National Academy of Sciences of the United States of America 106, no. 36 (September 2009): 15231-15236. Full Text
  - Nettles, DL, Chilkoti, A, and Setton, LA. "Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds." Tissue Eng Part A 15, no. 8 (August 2009): 2113-2121. Full Text Link to Item
  - Christensen, T, Amiram, M, Dagher, S, Trabbic-Carlson, K, Shamji, MF, Setton, LA, and Chilkoti, A. "Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins." Protein Sci 18, no. 7 (July 2009): 1377-1387. Full Text Link to Item
  - Hucknall, A, Rangarajan, S, and Chilkoti, A. "In Pursuit of Zero: Polymer Brushes that Resist the Adsorption of Proteins." Advanced Materials 21, no. 23 (June 19, 2009): 2441-2446. Full Text
  - Hucknall, A, Simnick, AJ, Hill, RT, Chilkoti, A, Garcia, A, Johannes, MS, Clark, RL, Zauscher, S, and Ratner, BD. "Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale." Biointerphases 4, no. 2 (June 2009): FA50-FA57. Full Text Link to Item
  - Zauscher, S, and Chilkoti, A. "Biological applications of polymer brushes. Preface." Biointerphases 4, no. 2 (June 2009): FA1-FA2. Full Text Link to Item
  - Nusz, GJ, Curry, AC, Marinakos, SM, Wax, A, and Chilkoti, A. "Rational selection of gold nanorod geometry for label-free plasmonic biosensors." Acs Nano 3, no. 4 (April 2009): 795-806. Full Text
  - Chilkoti, A. "Precision engineered control of biomolecules at interfaces by polymer brushes." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 237 (March 22, 2009). Link to Item
  - Chilkoti, A. "Designing interfaces for optical biosensors." Optics InfoBase Conference Papers (January 1, 2009).
  - Crow, M, Marinakos, S, Chilkoti, A, and Wax, A. "Simultaneous molecular imaging of EGFR and HER2 using hyperspectral darkfield microscopy and immunotargeted nanoparticles." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 7192 (2009). Full Text
  - Hucknall, A, Kim, D-H, Rangarajan, S, Hill, RT, Reichert, WM, and Chilkoti, A. "Simple fabrication of antibody microarrays on nonfouling polymer brushes with femtomolar sensitivity for protein analytes in serum and blood." Advanced Materials 21, no. 19 (2009): 1968-1971. Full Text
  - Wu, Y, MacKay, JA, McDaniel, JR, Chilkoti, A, and Clark, RL. "Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying." Biomacromolecules 10, no. 1 (January 2009): 19-24. Full Text
  - Kim, B, and Chilkoti, A. "Allosteric actuation of inverse phase transition of a stimulus-responsive fusion polypeptide by ligand binding." J Am Chem Soc 130, no. 52 (December 31, 2008): 17867-17873. Full Text Link to Item
  - Dhawan, A, Gerhold, M, Marinakos, S, Leonard, D, Wang, HN, Chilkoti, A, Russell, P, and Vo-Dinh, T. "Fabrication of fiber-optic sensors based on plasmon resonances of metallic nanostructures." Ecs Transactions 11, no. 14 (November 13, 2008): 41-55. Full Text
  - Cho, Y, Zhang, Y, Christensen, T, Sagle, LB, Chilkoti, A, and Cremer, PS. "Effects of Hofmeister anions on the phase transition temperature of elastin-like polypeptides." The Journal of Physical Chemistry. B 112, no. 44 (November 2008): 13765-13771. Full Text
  - Mackay, JA, and Chilkoti, A. "Temperature sensitive peptides: engineering hyperthermia-directed therapeutics." International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 24, no. 6 (September 2008): 483-495. (Review) Full Text
  - Xu, F, Joon, HM, Trabbic-Carlson, K, Chilkoti, A, and Knoll, W. "Surface plasmon optical study of the interfacial phase transition of elastinlike polypeptide grafted on gold." Biointerphases 3, no. 3 (September 2008): 66-74. Full Text Link to Item
  - Shamji, MF, Chen, J, Friedman, AH, Richardson, WJ, Chilkoti, A, and Setton, LA. "Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist." J Control Release 129, no. 3 (August 7, 2008): 179-186. Full Text Link to Item
  - Mock, JJ, Hill, RT, Degiron, A, Zauscher, S, Chilkoti, A, and Smith, DR. "Distance-dependent plasmon resonant coupling between a gold nanoparticle and gold film." Nano Letters 8, no. 8 (August 2008): 2245-2252. Full Text
  - Valiaev, A, Lim, DW, Schmidler, S, Clark, RL, Chilkoti, A, and Zauscher, S. "Hydration and conformational mechanics of single, end-tethered elastin-like polypeptides." Journal of the American Chemical Society 130, no. 33 (August 2008): 10939-10946. Full Text
  - Nettles, DL, Kitaoka, K, Hanson, NA, Flahiff, CM, Mata, BA, Hsu, EW, Chilkoti, A, and Setton, LA. "In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model." Tissue Engineering. Part A 14, no. 7 (July 2008): 1133-1140. Full Text
  - Shamji, MF, Whitlatch, L, Friedman, AH, Richardson, WJ, Chilkoti, A, and Setton, LA. "An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration." Spine 33, no. 7 (April 2008): 748-754. Full Text
  - Nusz, GJ, Marinakos, SM, Curry, AC, Dahlin, A, Höök, F, Wax, A, and Chilkoti, A. "Label-free plasmonic detection of biomolecular binding by a single gold nanorod." Analytical Chemistry 80, no. 4 (February 2008): 984-989. Full Text
  - Chilkoti, A. "Patterning materials with biomolecules." 8th World Biomaterials Congress 2008 4 (2008): 2249-2250.
  - Chow, D, Nunalee, ML, Lim, DW, Simnick, AJ, and Chilkoti, A. "Peptide-based Biopolymers in Biomedicine and Biotechnology." Materials Science & Engineering. R, Reports : a Review Journal 62, no. 4 (January 2008): 125-155. Full Text
  - Dreher, MR, Simnick, AJ, Fischer, K, Smith, RJ, Patel, A, Schmidt, M, and Chilkoti, A. "Temperature triggered self-assembly of polypeptides into multivalent spherical micelles." Journal of the American Chemical Society 130, no. 2 (January 2008): 687-694. Full Text
  - Lim, DW, Nettles, DL, Setton, LA, and Chilkoti, A. "In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair." Biomacromolecules 9, no. 1 (January 2008): 222-230. Full Text
  - Skala, MC, Marinakos, S, Chilkoti, A, and Izatt, JA. "Photothermal optical coherence tomography for molecular contrast imaging." Biomedical Optics, BIOMED 2008 (2008): BWF5-.
  - Chow, DC, and Chilkoti, A. "Surface-initiated enzymatic polymerization of DNA." Langmuir : the Acs Journal of Surfaces and Colloids 23, no. 23 (November 2007): 11712-11717. Full Text
  - Shamji, MF, Betre, H, Kraus, VB, Chen, J, Chilkoti, A, Pichika, R, Masuda, K, and Setton, LA. "Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic." Arthritis and Rheumatism 56, no. 11 (November 2007): 3650-3661. Full Text
  - Chilkoti, A. "Elastin biopolymers for drug delivery." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 234 (August 19, 2007). Link to Item
  - Garcia, A, Hucknall, A, Johannes, M, Clark, R, Chilkoti, A, and Zauscher, S. "POLY 627-Fabrication of bioconjugated and hybrid polymeric nanostructures by field-induced scanning probe lithography." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 234 (August 19, 2007). Link to Item
  - Kim, D-H, Smith, JT, Chilkoti, A, and Reichert, WM. "The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes." Biomaterials 28, no. 23 (August 2007): 3369-3377. Full Text
  - Roberts, SK, Chilkoti, A, and Setton, LA. "Multifunctional thermally transitioning oligopeptides prepared by ring-opening metathesis polymerization." Biomacromolecules 8, no. 8 (August 2007): 2618-2621. Full Text Link to Item
  - Dreher, MR, and Chilkoti, A. "Toward a systems engineering approach to cancer drug delivery." J Natl Cancer Inst 99, no. 13 (July 4, 2007): 983-985. Full Text Link to Item
  - Marinakos, SM, Chen, S, and Chilkoti, A. "Plasmonic detection of a model analyte in serum by a gold nanorod sensor." Analytical Chemistry 79, no. 14 (July 2007): 5278-5283. Full Text
  - Valiaev, A, Lim, DW, Oas, TG, Chilkoti, A, and Zauscher, S. "Force-induced prolyl cis-trans isomerization in elastin-like polypeptides." J Am Chem Soc 129, no. 20 (May 23, 2007): 6491-6497. Full Text Link to Item
  - Dreher, MR, Liu, W, Michelich, CR, Dewhirst, MW, and Chilkoti, A. "Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors." Cancer Research 67, no. 9 (May 2007): 4418-4424. Full Text
  - Lim, DW, Nettles, DL, Setton, LA, and Chilkoti, A. "Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution." Biomacromolecules 8, no. 5 (May 2007): 1463-1470. Full Text
  - Lim, DW, Trabbic-Carlson, K, Mackay, JA, and Chilkoti, A. "Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides." Biomacromolecules 8, no. 5 (May 2007): 1417-1424. Full Text
  - Curry, A, Nusz, G, Chilkoti, A, and Wax, A. "Analysis of total uncertainty in spectral peak measurements for plasmonic nanoparticle-based biosensors." Appl Opt 46, no. 10 (April 1, 2007): 1931-1939. Link to Item
  - Lee, W-K, Chen, S, Chilkoti, A, and Zauscher, S. "Fabrication of gold nanowires by electric-field-induced scanning probe lithography and in situ chemical development." Small 3, no. 2 (February 2007): 249-254. Full Text Link to Item
  - Christensen, T, Trabbic-Carlson, K, Liu, W, and Chilkoti, A. "Purification of recombinant proteins from Escherichia coli at low expression levels by inverse transition cycling." Analytical Biochemistry 360, no. 1 (January 2007): 166-168. Full Text
  - Lam, Y, Valiaev, A, Lim, D-W, Chilkoti, A, Alam, SM, and Zauscher, S. "Single molecule nanomechanics of HIV-1 envelope glycoproteins and elastin-like polypeptides." Proceedings of the SEM Annual Conference and Exposition on Experimental and Applied Mechanics 2007 1 (2007): 624-625.
  - Simnick, AJ, Lim, DW, Chow, D, and Chilkoti, A. "Biomedical and biotechnological applications of Elastin-like polypeptides." Polymer Reviews 47, no. 1 (2007): 121-154. Full Text
  - Valiaev, A, Abu-Lail, NI, Lim, DW, Chilkoti, A, and Zauscher, S. "Microcantilever sensing and actuation with end-grafted stimulus-responsive elastin-like polypeptides." Langmuir : the Acs Journal of Surfaces and Colloids 23, no. 1 (January 2007): 339-344. Full Text
  - Chilkoti, A, Christensen, T, and MacKay, JA. "Stimulus responsive elastin biopolymers: Applications in medicine and biotechnology." Current Opinion in Chemical Biology 10, no. 6 (December 2006): 652-657. (Review) Full Text
  - Liu, W, Dreher, MR, Furgeson, DY, Peixoto, KV, Yuan, H, Zalutsky, MR, and Chilkoti, A. "Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice." Journal of Controlled Release : Official Journal of the Controlled Release Society 116, no. 2 (November 2006): 170-178. Full Text
  - Liu, WE, Dreher, MR, Furgeson, DY, Peixoto, KV, Yuan, H, Zalutsky, MR, and Chilkoti, A. "Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice." Journal Of Controlled Release 116, no. 2 (November 2006): 170-178. (Academic Article)
  - Ge, X, Trabbic-Carlson, K, Chilkoti, A, and Filipe, CDM. "Purification of an elastin-like fusion protein by microfiltration." Biotechnol Bioeng 95, no. 3 (October 20, 2006): 424-432. Full Text Link to Item
  - Betre, H, Liu, W, Zalutsky, MR, Chilkoti, A, Kraus, VB, and Setton, LA. "A thermally responsive biopolymer for intra-articular drug delivery." Journal of Controlled Release : Official Journal of the Controlled Release Society 115, no. 2 (October 2006): 175-182. Full Text
  - Liu, W, Dreher, MR, Chow, DC, Zalutsky, MR, and Chilkoti, A. "Tracking the in vivo fate of recombinant polypeptides by isotopic labeling." Journal of Controlled Release : Official Journal of the Controlled Release Society 114, no. 2 (August 2006): 184-192. Full Text
  - Zhang, Y, Trabbic-Carlson, K, Albertorio, F, Chilkoti, A, and Cremer, PS. "Aqueous two-phase system formation kinetics for elastin-like polypeptides of varying chain length." Biomacromolecules 7, no. 7 (July 2006): 2192-2199. Full Text
  - Chow, DC, Dreher, MR, Trabbic-Carlson, K, and Chilkoti, A. "Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli." Biotechnology Progress 22, no. 3 (May 2006): 638-646. Full Text
  - Pyhtila, JW, Ma, H, Simnick, AJ, Chilkoti, A, and Wax, A. "Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry." J Biomed Opt 11, no. 3 (May 2006): 34022-. Full Text Link to Item
  - Ma, H, Li, D, Sheng, X, Zhao, B, and Chilkoti, A. "Protein-resistant polymer coatings on silicon oxide by surface-initiated atom transfer radical polymerization." Langmuir 22, no. 8 (April 11, 2006): 3751-3756. Full Text Link to Item
  - Abu-Lail, N, Kaholek, M, Valiaev, A, Lim, D-W, Chilkoti, A, LaMattina, B, Clark, R, and Zauscher, S. "Micro-cantilevers decorated with tethered stimulus-responsive polymer brushes and polypeptides for actuation and sensing." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 231 (March 26, 2006). Link to Item
  - Chilkoti, A. "Bionanofabrication with polymers and enzymes." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 231 (March 26, 2006). Link to Item
  - Lee, W-K, Chen, S, Chilkoti, A, and Zauscher, S. "Fabrication of bioconjugated polymeric nanostructures and metal nanowires by electric field-induced scanning probe lithography." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 231 (March 26, 2006). Link to Item
  - Ma, H, Wells, M, Beebe, TP, and Chilkoti, A. "Surface-Initiated Atom Transfer Radical Polymerization of Oligo(ethylene glycol) Methyl Methacrylate from a Mixed Self-Assembled Monolayer on Gold." Advanced Functional Materials 16, no. 5 (March 20, 2006): 640-648. Full Text
  - Dreher, MR, Liu, W, Michelich, CR, Dewhirst, MW, Yuan, F, and Chilkoti, A. "Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers." Journal of the National Cancer Institute 98, no. 5 (March 2006): 335-344. Full Text
  - Hyun, J, Chen, J, Setton, LA, and Chilkoti, A. "Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression." Biomaterials 27, no. 8 (March 2006): 1444-1451. Full Text Link to Item
  - Ma, H, Textor, M, Clark, RL, and Chilkoti, A. "Monitoring kinetics of surface initiated atom transfer radical polymerization by quartz crystal microbalance with dissipation." Biointerphases 1, no. 1 (March 2006): 35-. Full Text Link to Item
  - Ong, SR, Trabbic-Carlson, KA, Nettles, DL, Lim, DW, Chilkoti, A, and Setton, LA. "Epitope tagging for tracking elastin-like polypeptides." Biomaterials 27, no. 9 (March 2006): 1930-1935. Full Text
  - Betre, H, Ong, SR, Guilak, F, Chilkoti, A, Fermor, B, and Setton, LA. "Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide." Biomaterials 27, no. 1 (January 2006): 91-99. Full Text
  - Curry, A, Nusz, G, Chilkoti, A, and Wax, A. "Measurement system for the high-throughput characterization of metal nanoparticles for biosensors." Optics InfoBase Conference Papers (January 1, 2006).
  - Furgeson, DY, Dreher, MR, and Chilkoti, A. "Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors." Journal of Controlled Release : Official Journal of the Controlled Release Society 110, no. 2 (January 2006): 362-369. Full Text
  - McHale, MK, Setton, LA, and Chilkoti, A. "Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair." Tissue Engineering 11, no. 11-12 (November 2005): 1768-1779. Full Text
  - Zhang, Z, Ma, H, Hausner, DB, Chilkoti, A, and Beebe, TP. "Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption." Biomacromolecules 6, no. 6 (November 2005): 3388-3396. Full Text
  - Chow, DC, Lee, W-K, Zauscher, S, and Chilkoti, A. "Enzymatic fabrication of DNA nanostructures: extension of a self-assembled oligonucleotide monolayer on gold arrays." Journal of the American Chemical Society 127, no. 41 (October 2005): 14122-14123. Full Text
  - Chilkoti, A. "Passive and active surfaces to control protein and cell interactions." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230 (August 28, 2005): U4150-U4151. Link to Item
  - Chow, DC, Chilkoti, A, Lee, WK, and Zauscher, S. "Rapid fabrication of DNA nanostructures by enzymatic reactions." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230 (August 28, 2005): U1069-U1069. Link to Item
  - Valiaev, A, Abu-Lail, NI, Lim, DW, Chilkoti, A, and Zauscher, S. "Stimulus-responsive elastin-like polypetides as coatings for microcantilevers: Applications for sensing and actuation." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230 (August 28, 2005): U4317-U4318. Link to Item
  - Ge, X, Yang, DSC, Trabbic-Carlson, K, Kim, B, Chilkoti, A, and Filipe, CDM. "Self-cleavable stimulus responsive tags for protein purification without chromatography." J Am Chem Soc 127, no. 32 (August 17, 2005): 11228-11229. Full Text Link to Item
  - Curry, A, Nusz, G, Chilkoti, A, and Wax, A. "Substrate effect on refractive index dependence of plasmon resonance for individual silver nanoparticles observed using darkfield microspectroscopy." Opt Express 13, no. 7 (April 4, 2005): 2668-2677. Link to Item
  - Ma, H, Hyun, J, Zhang, Z, Beebe, TP, and Chilkoti, A. "Fabrication of Biofunctionalized Quasi-Three-Dimensional Microstructures of a Nonfouling Comb Polymer Using Soft Lithography." Advanced Functional Materials 15, no. 4 (April 2005): 529-540. Full Text
  - Chilkoti, A. "Nano- to micro-scale structures of polymers that repel and attract proteins." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 229 (March 13, 2005): U1158-U1158. Link to Item
  - Chilkoti, A, and Hubbell, JA. "Biointerface Science." MRS Bulletin 30, no. 03 (March 2005): 175-179. Full Text
  - Chilkoti, A. "Targeted drug delivery to solid tumors by thermally responsive polypeptides." European Cells and Materials 10, no. SUPPL.5 (2005): 11--.
  - Chow, DC, Johannes, MS, Lee, W-K, Clark, RL, Zauscher, S, and Chilkoti, A. "Nanofabrication with biomolecules." Materials Today 8, no. 12 SUPPL. 1 (2005): 30-39. Full Text
  - Curry, A, Nusz, G, Chilkoti, A, and Wax, A. "Measurement system for the high-throughput characterization of metal nanoparticles for biosensors." Optics InfoBase Conference Papers (January 1, 2005).
  - Curry, A, Nusz, G, Chilkoti, A, and Wax, A. "Measurement system for the high-throughput characterization of metal nanoparticles for biosensors." 2005 Conference on Lasers and Electro-Optics, CLEO 3 (2005): 2160-2162.
  - Haider, MA, Nettles, DL, Trabbic-Carlson, K, Chilkoti, A, and Setton, LA. "Predictive modeling of polypeptide hydrogel mechanical properties for cartilage repair using artificial neural networks." Proceedings of the 2005 Summer Bioengineering Conference 2005 (2005): 633-634.
  - Valiaev, A, Dong, WL, Chilkoti, A, Schmidler, S, and Zauscher, S. "Polypeptide-solvent interactions measured by single molecule force spectroscopy." Materials Research Society Symposium Proceedings 898 (2005): 92-97.
  - Valiaev, A, Lim, DW, Oas, T, Clark, RL, Chilkoti, A, and Zauscher, S. "Force-induced proline cis-trans isomerization in elastin-like polypeptides." BIOPHYSICAL JOURNAL 88, no. 1 (January 2005): 168A-168A. Link to Item
  - Trabbic-Carlson, K, Liu, L, Kim, B, and Chilkoti, A. "Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion." Protein Science : a Publication of the Protein Society 13, no. 12 (December 2004): 3274-3284. Full Text
  - Dreher, MR, Elas, M, Ichikawa, K, Barth, ED, Chilkoti, A, Rosen, GM, Halpern, HJ, and Dewhirst, M. "Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry." Medical Physics 31, no. 10 (October 2004): 2755-2762. Full Text
  - Nath, N, and Chilkoti, A. "Label-free biosensing by surface plasmon resonance of nanoparticles on glass: optimization of nanoparticle size." Analytical Chemistry 76, no. 18 (September 2004): 5370-5378. Full Text
  - Nath, N, and Chilkoti, A. "Label free colorimetric biosensing using nanoparticles." Journal of Fluorescence 14, no. 4 (July 2004): 377-389. (Review) Full Text
  - Hyun, J, Lee, W-K, Nath, N, Chilkoti, A, and Zauscher, S. "Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches"." Journal of the American Chemical Society 126, no. 23 (June 2004): 7330-7335. Full Text
  - Meyer, DE, and Chilkoti, A. "Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides." Biomacromolecules 5, no. 3 (May 2004): 846-851. Full Text
  - Hyun, J, Kim, J, Craig, SL, and Chilkoti, A. "Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold." Journal of the American Chemical Society 126, no. 15 (April 2004): 4770-4771. Full Text
  - Ma, H, Hyun, J, Stiller, P, and Chilkoti, A. "“Non-Fouling” Oligo(ethylene glycol)- Functionalized Polymer Brushes Synthesized by Surface-Initiated Atom Transfer Radical Polymerization." Advanced Materials 16, no. 4 (February 17, 2004): 338-341. Full Text
  - Nath, N, Hyun, J, Ma, H, and Chilkoti, A. "Surface engineering strategies for control of protein and cell interactions." Surface Science 570, no. 1-2 (2004): 98-110. Full Text
  - Piervincenzi, RT, and Chilkoti, A. "Effect of genetic circular permutation near the active site on the activity and stability of an enzyme inhibitor." Biomolecular Engineering 21, no. 1 (January 2004): 33-42. Full Text
  - Trabbic-Carlson, K, Meyer, DE, Liu, L, Piervincenzi, R, Nath, N, LaBean, T, and Chilkoti, A. "Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity?." Protein Engineering, Design & Selection : Peds 17, no. 1 (January 2004): 57-66. Full Text
  - Wong, JY, Plant, AL, Schmidt, CE, Shea, L, Coury, AJ, Chen, CS, Barron, AE, Klok, H-A, Deming, TJ, Saltzman, WM, Chilkoti, A, Luo, D, and Uhrich, K. "Materials Research Society Symposium Proceedings: Preface." Materials Research Society Symposium Proceedings EXS, no. 1 (2004): xvii-.
  - Dreher, MR, Raucher, D, Balu, N, Michael Colvin, O, Ludeman, SM, and Chilkoti, A. "Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy." Journal of Controlled Release : Official Journal of the Controlled Release Society 91, no. 1-2 (August 2003): 31-43. Full Text
  - Trabbic-Carlson, K, Setton, LA, and Chilkoti, A. "Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides." Biomacromolecules 4, no. 3 (May 2003): 572-580. Full Text
  - Nath, N, and Chilkoti, A. "Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide." Anal Chem 75, no. 4 (February 15, 2003): 709-715. Link to Item
  - Frey, W, Meyer, DE, and Chilkoti, A. "Dynamic Addressing of a Surface Pattern by a Stimuli-Responsive Fusion Protein." Advanced Materials 15, no. 3 (February 5, 2003): 248-251. Full Text
  - Chan, BP, Chilkoti, A, Reichert, WM, and Truskey, GA. "Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells." Biomaterials 24, no. 4 (February 2003): 559-570. Link to Item
  - Blomfield, CJ, Roberts, AJ, Hutton, SJ, Ma, H, Hyun, J, and Chilkoti, A. "X-ray photoelectron spectroscopy as a tool for bio-surface analysis." European Cells and Materials 6, no. SUPPL. 1 (2003): 60--.
  - Frey, W, Meyer, DE, and Chilkoti, A. "Thermodynamically reversible addressing of a stimuli responsive fusion protein onto a patterned surface template." Langmuir 19, no. 5 (2003): 1641-1653. Full Text
  - Hyun, J, Ma, H, Zhang, Z, Jr, TPB, and Chilkoti, A. "Universal route to cell micropatterning using an amphiphilic comb polymer." Advanced Materials 15, no. 7-8 (2003): 576-579.
  - Ma, H, Hyun, J, Nath, N, and Chilkoti, A. "Surface engineering strategies for control of protein and cell interactions." European Cells and Materials 6, no. SUPPL. 1 (2003): 16-17.
  - Valiaev, A, Clark, RL, Chilkoti, A, and Zauscher, S. "Conformational Mechanics of Stimulus-Responsive Polypeptides." Proceedings of SPIE - The International Society for Optical Engineering 5053 (2003): 31-40. Full Text
  - Chilkoti, A, Dreher, MR, and Meyer, DE. "Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery." Adv Drug Deliv Rev 54, no. 8 (October 18, 2002): 1093-1111. (Review) Link to Item
  - Nath, N, and Chilkoti, A. "Creating “Smart” Surfaces Using Stimuli Responsive Polymers." Advanced Materials 14, no. 17 (September 3, 2002): 1243-1247. Full Text
  - Betre, H, Setton, LA, Meyer, DE, and Chilkoti, A. "Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair." Biomacromolecules 3, no. 5 (September 2002): 910-916. Link to Item
  - Chilkoti, A, Dreher, MR, Meyer, DE, and Raucher, D. "Targeted drug delivery by thermally responsive polymers." Advanced Drug Delivery Reviews 54, no. 5 (September 2002): 613-630. (Review) Full Text
  - Chilkoti, A, and Nath, N. "A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real-time on a surface." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224 (August 18, 2002): U151-U151. Link to Item
  - Meyer, DE, and Chilkoti, A. "Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system." Biomacromolecules 3, no. 2 (March 2002): 357-367. Full Text
  - Nath, N, and Chilkoti, A. "A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface." Analytical Chemistry 74, no. 3 (February 2002): 504-509. Full Text
  - Betre, H, Chilkoti, A, and Setton, LA. "A two-step chondrocyte recovery system based on thermally sensitive elastin-like polypeptide scaffolds for cartilage tissue engineering." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (2002): 829-830.
  - Dreher, M, Raucher, D, Balu, N, Colvin, M, Ludeman, S, and Chilkoti, A. "Elastin-like polypeptide-doxorubicin conjugates for cancer therapy." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (2002): 524-525.
  - Hyun, J, Ahn, SJ, Lee, WK, Chilkoti, A, and Zauscher, S. "Molecular recognition-mediated fabrication of protein nanostructures by dip-pen lithography." Nano Lett. (USA) 2, no. 11 (2002): 1203-1207. (Academic Article) Full Text Link to Item
  - Hyun, J, Ahn, SJ, Lee, WK, Chilkoti, A, and Zauscher, S. "Molecular Recognition-Mediated Fabrication of Protein Nanostructures by Dip-Pen Lithography." Nano Letters 2, no. 11 (2002): 1203-1207. Full Text
  - Hyun, J, Ma, H, Banerjee, P, Cole, J, Gonsalves, K, and Chilkoti, A. "Micropatterns of a cell-adhesive peptide on an amphiphilic comb polymer film." Langmuir 18, no. 8 (2002): 2975-2979. Full Text
  - Nath, N, and Chilkoti, A. "An immobilized gold nanoparticle sensor for label free optical detection of biomolecular interactions." Proceedings of SPIE - The International Society for Optical Engineering 4626 (2002): 441-448. Full Text
  - Nath, N, and Chilkoti, A. "Creating "smart" surfaces using stimuli responsive polymers." Advanced Materials 14, no. 17 (2002): 1243-1247+1181. Full Text
  - Nath, N, and Chilkoti, A. "A colorimetric gold nanoparticle biosensor: Effect of particle size on sensitivity." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (2002): 574-575.
  - Rao, GVR, Balamurugan, S, Meyer, DE, Chilkoti, A, and López, GP. "Hybrid bioinorganic smart membranes that incorporate protein-based molecular switches." Langmuir 18, no. 5 (2002): 1819-1824. Full Text
  - Raucher, D, and Chilkoti, A. "Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition." Cancer Res 61, no. 19 (October 1, 2001): 7163-7170. Link to Item
  - Nath, N, and Chilkoti, A. "Interfacial phase transition of an environmentally responsive elastin biopolymer adsorbed on functionalized gold nanoparticles studied by colloidal surface plasmon resonance." J Am Chem Soc 123, no. 34 (August 29, 2001): 8197-8202. Link to Item
  - Chilkoti, A. "Biomedical applications of genetically encoded elastin biopolymers." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 222 (August 2001): U421-U421. Link to Item
  - Hyun, J, and Chilkoti, A. "Micropatterning biological molecules on a polymer surface using elastomeric microwells." J Am Chem Soc 123, no. 28 (July 18, 2001): 6943-6944. Link to Item
  - Meyer, DE, Shin, BC, Kong, GA, Dewhirst, MW, and Chilkoti, A. "Drug targeting using thermally responsive polymers and local hyperthermia." Journal of Controlled Release : Official Journal of the Controlled Release Society 74, no. 1-3 (July 2001): 213-224. Full Text
  - Meyer, DE, Trabbic-Carlson, K, and Chilkoti, A. "Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin." Biotechnol Prog 17, no. 4 (July 2001): 720-728. Full Text Link to Item
  - Chilkoti, A, and Nath, N. "Phase transition of environmentally responsive elastin biopolymers adsorbed on gold nanoparticles studied by colloidal surface plasmon resonance." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 221 (April 1, 2001): U366-U366. Link to Item
  - Meyer, DE, Kong, GA, Dewhirst, MW, Zalutsky, MR, and Chilkoti, A. "Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia." Cancer Research 61, no. 4 (February 2001): 1548-1554.
  - Belu, AM, Yang, Z, Aslami, R, and Chilkoti, A. "Enhanced TOF-SIMS imaging of a micropatterned protein by stable isotope protein labeling." Anal Chem 73, no. 2 (January 15, 2001): 143-150. Link to Item
  - Hyun, J, Zhu, Y, Liebmann-Vinson, A, Jr, TPB, and Chilkoti, A. "Microstamping on an activated polymer surface: Patterning biotin and streptavidin onto common polymeric biomaterials." Langmuir 17, no. 20 (2001): 6358-6367. Full Text
  - Hyun, J, and Chilkoti, A. "Surface-initiated free radical polymerization of polystyrene micropatterns on a self-assembled monolayer on gold." Macromolecules 34, no. 16 (2001): 5644-5652. Full Text
  - Frey, W, Woods, CK, and Chilkoti, A. "Ultraflat Nanosphere Lithography: A New Method to Fabricate Flat Nanostructures." Advanced Materials 12, no. 20 (October 2000): 1515-1519. Full Text
  - Chilkoti, A, Meyer, DE, Kong, GH, Dewhirst, MW, Foulon, C, and Zalutsky, MR. "Genetically engineered biopolymer conjugate for thermal targeting of anticancer therapeutics." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 219 (March 26, 2000): U453-U453. Link to Item
  - Chilkoti, A, Yang, ZP, and Belu, AM. "Microstamping of biological ligands on activated polymer surfaces." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 219 (March 26, 2000): U573-U573. Link to Item
  - Stayton, PS, Hoffman, AS, Murthy, N, Lackey, C, Cheung, C, Tan, P, Klumb, LA, Chilkoti, A, Wilbur, FS, and Press, OW. "Molecular engineering of proteins and polymers for targeting and intracellular delivery of therapeutics." Journal of Controlled Release : Official Journal of the Controlled Release Society 65, no. 1-2 (March 2000): 203-220. Full Text
  - Yang, Z, and Chilkoti, A. "Microstamping of a Biological Ligand onto an Activated Polymer Surface." Advanced Materials 12, no. 6 (March 2000): 413-417. Full Text
  - Chilkoti, A, Hyun, J, Belu, A, and Yang, Z. "Microstamping of biological ligands on activated polymer surfaces." Annals of Biomedical Engineering 28, no. SUPPL 1 (2000): 92-. (Academic Article)
  - Chilkoti, A, Hyun, J, Belu, A, and Yang, Z. "Microstamping of biological ligands on activated polymer surfaces." Annals of Biomedical Engineering 28, no. SUPPL. 1 (2000): S-92.
  - Frey, W, Woods, CK, and Chilkoti, A. "Ultraflat nanosphere lithography: A new method to fabricate flat nanostructures." Advanced Materials 12, no. 20 (2000): 1515-1519. Full Text
  - Frey, W, and Chilkoti, A. "Ultraflat nanosphere lithography: functionalized nanostructures for biomedical applications." Annals of Biomedical Engineering 28, no. SUPPL 1 (2000): 94-. (Academic Article)
  - Frey, W, and Chilkoti, A. "Ultraflat nanosphere lithography: functionalized nanostructures for biomedical applications." Annals of Biomedical Engineering 28, no. SUPPL. 1 (2000): S-94.
  - Hoffman, AS, Stayton, PS, Bulmus, V, Chen, G, Chen, J, Cheung, C, Chilkoti, A, Ding, Z, Dong, L, Fong, R, Lackey, CA, Long, CJ, Miura, M, Morris, JE, Murthy, N, Nabeshima, Y, Park, TG, Press, OW, Shimoboji, T, Shoemaker, S, Yang, HJ, Monji, N, Nowinski, RC, Cole, CA, Priest, JH, Harris, JM, Nakamae, K, Nishino, T, and Miyata, T. "Really smart bioconjugates of smart polymers and receptor proteins." Journal of Biomedical Materials Research 52, no. 4 (2000): 577-586. Full Text
  - Hoffman, AS, Stayton, PS, Bulmus, V, Chen, G, Chen, J, Cheung, C, Chilkoti, A, Ding, Z, Dong, L, Fong, R, Lackey, CA, Long, CJ, Miura, M, Morris, JE, Murthy, N, and al, E. "Really smart bioconjugates of smart polymers and receptor proteins." Journal of Biomedical Materials Research 52, no. 4 (2000): 577-586. (Academic Article) Full Text Link to Item
  - Meyer, D, and Chilkoti, A. "Engineered fusion protein of an elastin-like polypeptide and autofluorescent proteins: a genetically encodable nanobiosensor." Annals of Biomedical Engineering 28, no. SUPPL 1 (2000): 95-. (Academic Article)
  - Meyer, D, and Chilkoti, A. "Engineered fusion protein of an elastin-like polypeptide and autofluorescent proteins: a genetically encodable nanobiosensor." Annals of Biomedical Engineering 28, no. SUPPL. 1 (2000): S-95.
  - Meyer, D, and Chilkoti, A. "Elastin-like polypeptides as thermally targeted drug carriers." Annals of Biomedical Engineering 28, no. SUPPL. 1 (2000): S-20.
  - Meyer, DE, Kong, GA, Dewhirst, MW, Foulon, C, Zalutsky, MR, and Chilkoti, A. "Genetically engineered polypeptide carrier for thermal targeting of anticancer therapeutics." American Chemical Society, Polymer Preprints, Division of Polymer Chemistry 41, no. 1 (2000): 1020-1021.
  - Yang, Z, Belu, AM, Liebmann-Vinson, A, Sugg, H, and Chilkoti, A. "Molecular imaging of a micropatterned biological ligand on an activated polymer surface." Langmuir 16, no. 19 (2000): 7482-7492. Full Text
  - Yang, Z, Frey, W, Oliver, T, and Chilkoti, A. "Light-activated affinity micropatterning of proteins on self-assembled monolayers on gold." Langmuir (USA) 16, no. 4 (2000): 1751-1758. (Academic Article) Full Text Link to Item
  - Yang, Z, Frey, W, Oliver, T, and Chilkoti, A. "Light-activated affinity micropatterning of proteins on self-assembled monolayers on gold." Langmuir 16, no. 4 (2000): 1751-1758. Full Text
  - Yang, Z, and Chilkoti, A. "Microstamping of a biological ligand onto an activated polymer surface." Advanced Materials 12, no. 6 (January 1, 2000): 413-417. Full Text
  - Yang, Z, and Chilkoti, A. "Microstamping of a biological ligand onto an activated polymer surface." Advanced Materials 12, no. 6 (2000): 413-417. Full Text
  - Freitag, S, Le Trong, I, Klumb, LA, Chu, V, Chilkoti, A, Stayton, PS, and Stenkamp, RE. "X-ray crystallographic studies of streptavidin mutants binding to biotin." Biomol Eng 16, no. 1-4 (December 31, 1999): 13-19. Link to Item
  - Stayton, PS, Freitag, S, Klumb, LA, Chilkoti, A, Chu, V, Penzotti, JE, To, R, Hyre, D, Le Trong, I, Lybrand, TP, and Stenkamp, RE. "Streptavidin-biotin binding energetics." Biomolecular Engineering 16, no. 1-4 (December 1999): 39-44. (Review) Full Text
  - Wong, J, Chilkoti, A, and Moy, VT. "Direct force measurements of the streptavidin-biotin interaction." Biomolecular Engineering 16, no. 1-4 (December 1999): 45-55. Full Text
  - Meyer, DE, and Chilkoti, A. "Purification of recombinant proteins by fusion with thermally-responsive polypeptides." Nat Biotechnol 17, no. 11 (November 1999): 1112-1115. Full Text Link to Item
  - Meyer, DE, and Chilkoti, A. "Polypeptide fusion tag for thermal purification of recombinant proteins." ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 217 (March 21, 1999): U177-U177. Link to Item
  - Meyer, DE, Kong, G, Dewhirst, M, and Chilkoti, A. "Genetically-engineered polypeptide carrier for thermal targeting of therapeutics." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 2 (1999): 1289--.
  - Piervincenzi, RT, and Chilkoti, A. "Controlling the orientation of immobilized proteins by genetic circular permutation." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (1999): 93--.
  - Yang, ZP, and Chilkoti, A. "Light-activated affinity micropatterning of proteins." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 2 (1999): 738--.
  - Freitag, S, Le Trong, I, Chilkoti, A, Klumb, LA, Stayton, PS, and Stenkamp, RE. "Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex." J Mol Biol 279, no. 1 (May 29, 1998): 211-221. Full Text Link to Item
  - Hoffman, AS, Stayton, PS, Shimoboji, T, Chen, G, Ding, Z, Chilkoti, A, Long, C, Miura, M, Chen, J, Park, T, Monji, N, Cole, C-A, Harris, JM, and Nakamae, K. "Conjugates of Stimuli-Responsive Polymers and Biomolecules: Random and Site-Specific Conjugates of Temperature-Sensitive Polymers and Proteins." Macromolecular Symposia 118 (1997): 553-563.
  - Frey, W, Schief, WR, Pack, DW, Chen, CT, Chilkoti, A, Stayton, P, Vogel, V, and Arnold, FH. "Two-dimensional protein crystallization via metal-ion coordination by naturally occurring surface histidines." Proc Natl Acad Sci U S A 93, no. 10 (May 14, 1996): 4937-4941. Link to Item
  - Shimoboji, T, Stayton, PS, Long, C, Chilkoti, A, Chen, G, Harris, JM, and Hoffman, AS. "Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein." Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium 1 (1996): 897--.
  - Chilkoti, A, Boland, T, Ratner, BD, and Stayton, PS. "The relationship between ligand-binding thermodynamics and protein-ligand interaction forces measured by atomic force microscopy." Biophys J 69, no. 5 (November 1995): 2125-2130. Full Text Link to Item
  - Chilkoti, A, Schwartz, BL, Smith, RD, Long, CJ, and Stayton, PS. "Engineered chimeric streptavidin tetramers as novel tools for bioseparations and drug delivery." Biotechnology (N Y) 13, no. 11 (November 1995): 1198-1204. Link to Item
  - Stayton, PS, Shimoboji, T, Long, C, Chilkoti, A, Chen, G, Harris, JM, and Hoffman, AS. "Control of protein-ligand recognition using a stimuli-responsive polymer." Nature 378, no. 6556 (November 1995): 472-474. Full Text
  - Chilkoti, A, Schmierer, AE, Pérez-Luna, VH, and Ratner, BD. "Investigating the relationship between surface chemistry and endothelial cell growth: partial least-squares regression of the static secondary ion mass spectra of oxygen-containing plasma-deposited films." Anal Chem 67, no. 17 (September 1, 1995): 2883-2891. Link to Item
  - Schwartz, BL, Bruce, JE, Anderson, GA, Hofstadler, SA, Rockwood, AL, Smith, RD, Chilkoti, A, and Stayton, PS. "Dissociation of tetrameric ions of noncovalent streptavidin complexes formed by electrospray ionization." Journal of the American Society for Mass Spectrometry 6, no. 6 (June 1995): 459-465. Full Text
  - Chilkoti, A, Tan, PH, and Stayton, PS. "Site-directed mutagenesis studies of the high-affinity streptavidin-biotin complex: contributions of tryptophan residues 79, 108, and 120." Proc Natl Acad Sci U S A 92, no. 5 (February 28, 1995): 1754-1758. Link to Item
  - Chilkoti, A, and Stayton, PS. "Molecular origins of the slow streptavidin-biotin dissociation kinetics." Journal of the American Chemical Society 117, no. 43 (1995): 10622-10628.
  - Schwartz, BL, Gale, DC, Smith, RD, Chilkoti, A, and Stayton, PS. "Investigation of non-covalent ligand binding to the intact streptavidin tetramer by electrospray ionization mass spectrometry." Journal of Mass Spectrometry 30, no. 8 (1995): 1095-1102. Full Text
  - Chilkoti, A, Chen, G, Stayton, PS, and Hoffman, AS. "Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein." Bioconjug Chem 5, no. 6 (November 1994): 504-507. Link to Item
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Static secondary ion mass spectrometric investigation of the surface chemistry of organic plasma-deposited films created from oxygen-containing precursors. 3. Multivariate statistical modeling." Anal Chem 65, no. 13 (July 1, 1993): 1736-1745. Link to Item
  - Chilkoti, A, Lopez, GP, and Ratner, BD. "Analysis of polymer surfaces by SIMS. 16. investigation of surface cross-linking in polymer gels of 2-hydroxyethyl methacrylate." Macromolecules 26, no. 18 (1993): 4825-4832.
  - Chilkoti, A, and Ratner, BD. "X-ray photoelectron spectroscopy of iodine-doped nonconjugated polymers." Chemistry of Materials 5, no. 6 (1993): 786-792.
  - Ratner, BD, Tyler, BJ, and Chilkoti, A. "Analysis of biomedical polymer surfaces: polyurethanes and plasma-deposited thin films." Clin Mater 13, no. 1-4 (1993): 71-84. (Review) Link to Item
  - Stayton, PS, Chilkoti, A, Long, CJ, Pettit, DK, Tan, PHS, Chen, G, and Hoffman, AS. "Engineered proteins for biomaterials." Materials Research Society Symposium Proceedings 292 (1993): 77-82.
  - Leggett, GJ, Chilkoti, A, Ratner, BD, and Vickerman, JC. "A tandem SIMS study of poly(vinyl methyl ether)." Surface and Interface Analysis 18, no. 3 (March 1992): 210-216. Full Text
  - Chilkoti, A, Ratner, BD, Briggs, D, and Reich, F. "Static secondary ion mass spectrometry of organic plasma-deposited films created from stable isotope-labeled precursors. II. Mixtures of acetone and oxygen." Journal of Polymer Science, Part A: Polymer Chemistry 30, no. 7 (1992): 1261-1278. Full Text
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Analysis of polymer surfaces by SIMS: part 15. oxygen-functualized aliphatic homopolymers." Surface and Interface Analysis 18, no. 8 (1992): 604-618.
  - Lopez, GP, Chilkoti, A, Briggs, D, and Ratner, BD. "Substrate temperature effects on film chemistry in plasma deposition of organics. III. Analysis by static secondary ion mass spectrometry." Journal of Polymer Science, Part A: Polymer Chemistry 30, no. 11 (1992): 2427-2441. Full Text
  - Ratner, BD, Chilkoti, A, and Castner, DG. "Contemporary methods for characterizing complex biomaterial surfaces." Clinical Materials 11, no. 1-4 (1992): 25-36.
  - Ertel, SI, Chilkoti, A, Horbett, TA, and Ratner, BD. "Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups." Journal of biomaterials science. Polymer edition 3, no. 2 (December 1, 1991): 163-183.
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Static secondary-ion mass spectrometric investigation of the surface structure of organic plasma-deposited films prepared from stable-isotope-labeled precursors. 1. Carbonyl precursors." Anal Chem 63, no. 15 (August 1, 1991): 1612-1620. Link to Item
  - Chilkoti, A, Castner, DG, and Ratner, BD. "Static Secondary Ion Mass Spectrometry and X-Ray Photoelectron Spectroscopy of Deuterium- and Methyl-Substituted Polystyrene." Applied Spectroscopy 45, no. 2 (February 1991): 209-217. Full Text
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Plasma-deposited polymeric films prepared from carbonyl-containing volatile precursors: XPS chemical derivatization and static SIMS surface characterization." Chemistry of Materials 3, no. 1 (1991): 51-61.
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Structural elucidation of oxygen-containing plasma deposited films by static secondary ion mass spectrometry." Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium 14 (1991): 180--.
  - Chilkoti, A, and Ratner, BD. "X-ray photoelectron spectroscopic investigation of the selectivity of hydroxyl derivatization reactions." Surface and Interface Analysis 17, no. 8 (1991): 567-574.
  - Ertel, SI, Chilkoti, A, Horbett, TA, and Ratner, BD. "Endothelial cell growth on oxygen-containing films deposited by radio-frequency plasmas: the role of surface carbonyl groups." J Biomater Sci Polym Ed 3, no. 2 (1991): 163-183. Link to Item
  - Leggett, GJ, Chilkoti, A, Castner, DG, Ratner, BD, and Vickerman, JC. "Direct emission of molecular fragments during the sputtering of poly(4-hydroxystyrene) and determination of ion structures using tandem secondary ion mass spectrometry." International Journal of Mass Spectrometry and Ion Processes 108, no. 1 (1991): 29-39. Full Text
  - Chilkoti, A, Castner, DG, Ratner, BD, and Briggs, D. "Surface characterization of a poly(styrene/ p ‐hydroxystyrene) copolymer series using x‐ray photoelectron spectroscopy, static secondary ion mass spectrometry, and chemical derivatization techniques." Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films 8, no. 3 (May 1990): 2274-2282. Full Text
  - Chilkoti, A, Ratner, BD, and Briggs, D. "Static SIMS investigation of the surface structure of plasma deposited films prepared from stable isotope-labeled carbonyl precursors." Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering 62 (1990): 135-139.
  - Chilkoti, A, and Ratner, BD. "Effect of monomer type on the surface chemistry of rf-plasma deposited surfaces prepared for cell culture." Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering 59 (1988): 258-262.
- Book Sections
  - Hill, RT, and Chilkoti, A. "Surface Patterning." In Biomaterials Science: An Introduction to Materials: Third Edition, 276-301. January 1, 2013. Full Text
  - Nusz, G, and Chilkoti, A. "Individual plasmonic nanostructures as label free biosensors." In Nanoplasmonic Sensors, 105-126. January 1, 2012. Full Text
  - Bhattacharyya, J, Bellucci, JJ, and Chilkoti, A. "Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering(Published online)." In Biomaterials from Nature for Advanced Devices and Therapies, 106-126.: John Wiley & Sons, Inc.,. Full Text
- Conference Papers
  - Bhattacharyya, J, and Chilkoti, A. "Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors." October 1, 2014. Full Text
  - Liu, W, Mukerji, R, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, M, and Chilkoti, A. "Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor." October 1, 2014. Full Text
  - Chilkoti, A. "Surface initiated polymerization and its applications in medicine." August 10, 2014. Link to Item
  - Chilkoti, A. "Genetically encoded polypeptide nanoparticles for delivery of drugs." March 16, 2014. Link to Item
  - Quiroz, FG, and Chilkoti, A. "The language of protein polymers." January 1, 2014. Full Text
  - Chilkoti, A. "Genetically engineered polypeptide conjugates and fusions for drug delivery." September 8, 2013. Link to Item
  - Chilkoti, A. "Syntax of "smart" peptide polymers governs their function." September 8, 2013. Link to Item
  - Garanger, E, Mac Ewan, S, Brulet, A, Bataille, L, Sandre, O, Chilkoti, A, and Lecommandoux, S. "Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly." September 8, 2013. Link to Item
  - Tang, L, Tjong, V, Gu, R, Chilkoti, A, and Zauscher, S. "Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles." September 8, 2013. Link to Item
  - Weinberger, A, Macewan, S, Schmatko, T, Schroder, A, Chilkoti, A, and Marques, CM. "Interactions of elastin-like polypeptides with model membranes on GUVs." July 2013. Link to Item
  - Bhattacharyya, J, McDaniel, J, and Chilkoti, A. "Abstract 4509: Genetically encoded chimeric polypeptide nanoparticles for paclitaxel delivery to triple negative breast cancer." April 15, 2013. Full Text
  - Liu, W, McDaniel, JR, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, MR, and Chilkoti, A. "Abstract 4341: A novel injectable polymer liquid that self-assembles into radioactive “seeds” for brachytherapy." April 15, 2013. Full Text
  - Schaal, JL, Liu, W, Li, X, Zalutsky, M, and Chilkoti, A. "Abstract 5615: Evaluation of the antitumoral efficacy and toxicity of injectable, polymeric radionuclide seeds in a noninvasive preclinical prostate tumor model." April 15, 2013. Full Text
  - Caudill, C, Bhattacharyya, J, and Chilkoti, A. "Delivery of paclitaxel with elastin-like polypeptides." April 7, 2013. Link to Item
  - Sinclair, SM, Bhattacharyya, J, Little, D, Bowles, RD, Gooden, DM, Toone, EJ, Chilkoti, A, and Setton, LA. "PHARMACOKINETICS OF A THERMALLY RESPONSIVE CURCUMIN CONJUGATE FOR LOCAL ANTAGONISM OF NEUROINFLAMMATION IN DISC HERNIATION." April 2013. Full Text Link to Item
  - Chilkoti, A. "Biomolecular toolbox for the in situ synthesis of protein-polymer conjugates." August 19, 2012. Link to Item
  - Chilkoti, A. "Genetically encoded stimulus responsive elastin-like polypeptides: Applications in drug delivery." March 25, 2012. Link to Item
  - Ferris, R, Hucknall, A, Kwon, BS, Chilkoti, A, and Zauscher, S. "Field-induced nanolithography for the patterning of non-fouling polymer brushes." March 25, 2012. Link to Item
  - Fluegel, S, Kiefer, T, Heimann, N, Buehler, J, Fischer, K, McDaniel, J, Chilkoti, A, and Schmidt, M. "Conjugates of polypeptides and synthetic polymers with oligonucleotides: Stars, micelles and multiblockcopolymers." March 25, 2012. Link to Item
  - Chilkoti, A. "PMSE 446-Architecture of polymer-drug conjugate controls in vivo fate and efficacy." August 17, 2008. Link to Item
  - Chilkoti, A. "PMSE 206-Architecture of polymer-drug conjugate controls in vivo fate and efficacy." April 6, 2008. Link to Item
  - Chilkoti, A. "POLY 351-Thermally responsive elastin biopolymers for drug delivery." April 6, 2008. Link to Item
  - Liu, W, Dreher, MR, Chow, DC, Zalutsky, MR, and Chilkoti, A. "Tracking the in vivo fate of recombinant polypeptides by isotopic labeling." 3rd International Nanomedicine and Drug Delivery Symposium. Baltimore, MD. September 26, 2005 - September 27, 2005.: ELSEVIER SCIENCE BV, August 28, 2006. Full Text Link to Item
  - Dagher, S, Rose, D, and Chilkoti, A. "Novel technology for cost-effective expression and purification of recombinant proteins and peptides." 2005. Link to Item
  - Dagher, S, Rose, D, and Chilkoti, A. "Novel technology for cost-effective expression and purification of recombinant proteins and peptides." 2005. Link to Item
  - Wong, JY, Plant, AL, Schmidt, CE, Shea, L, Coury, AJ, Chen, CS, Barron, AE, Klok, HA, Deming, TJ, Saltzman, WM, Chilkoti, A, Luo, D, and Uhrich, K. "Materials Research Society Symposium Proceedings: Preface." December 1, 2004.
  - Valiaev, A, Lim, DW, Clark, R, Chilkoti, A, and Zauscher, S. "Mechanics of stimulus-responsive elastin-like polypeptides studied by force spectroscopy." August 22, 2004. Link to Item
  - Kaholek, M, Hyun, J, Lee, WK, Chilkoti, A, and Zauscher, S. "Fabrication of "smart" biomolecular and polymeric nanostructures using molecular recognition, surface-initiated nanopolymerization and scanning probe lithography." March 28, 2004. Link to Item
  - Prohaska, S, Dreher, M, Dewhirst, MW, Chilkoti, A, Pries, AR, Westerhoff, M, and Cornelissen, AJM. "3-D reconstruction of tumor vascular networks." 2004. Link to Item
  - Nath, N, Chilkoti, A, Zauscher, S, Hyun, JH, and Lee, WK. "Non-covalent, environmentally modulated molecular recognition between ELP biopolymers: A convenient route to reversible protein arrays." September 2003. Link to Item
  - Zauscher, S, Chilkoti, A, Hyun, J, and Lee, WK. "Fabrication of "smart" protein nanostructures using molecular recognition and dip-pen nano-lithography." September 2003. Link to Item
  - Chilkoti, A, Ma, HW, Hyun, J, and Nath, N. "Passive and active nonfouling polymer grafts." March 2003. Link to Item
  - Chilkoti, A. "Nanoparticle biosensors." March 2003. Link to Item
  - Zauscher, S, Chilkoti, A, Ahn, SJ, Hyun, J, and Lee, WK. "Fabrication of surface confined, stimulus-responsive polymer nanostructures using dip-pen nanolithography." March 2003. Link to Item
  - Hoffman, AS, Stayton, PS, Bulmus, V, Chen, G, Chen, J, Cheung, C, Chilkoti, A, Ding, Z, Dong, L, Fong, R, Lackey, CA, Long, CJ, Miura, M, Morris, JE, Murthy, N, Nabeshima, Y, Park, TG, Press, OW, Shimoboji, T, Shoemaker, S, Yang, HJ, Monji, N, Nowinski, RC, Cole, CA, Priest, JH, Harris, JM, Nakamae, K, Nishino, T, and Miyata, T. "Really smart bioconjugates of smart polymers and receptor proteins." : Wiley, December 15, 2000. Full Text
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Outreach & Engaged Scholarship
- Duke Global Health Outreach. Multiplexed 2-D Diffusion Point-of-Care Test for Serum Markers of Cancer. December 2013 2013

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Education, Training, & Certifications

Duke Appointment History

In the News

Awards & Honors

Global Scholarship

Research

Teaching

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Selected Publications

Academic Articles

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Outreach & Engaged Scholarship