Overview
Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University.
My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.
Current Appointments & Affiliations
Alan L. Kaganov Distinguished Professor of Biomedical Engineering
·
2016 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor of Biomedical Engineering
·
2006 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor in the Department of Chemistry
·
2009 - Present
Chemistry,
Trinity College of Arts & Sciences
Research Professor of Global Health
·
2020 - Present
Duke Global Health Institute,
University Institutes and Centers
Member of the Duke Cancer Institute
·
1996 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
The Polymers of Life: Exploring Cellular Function Through Polymer Concepts.
Journal Article Advanced science (Weinheim, Baden-Wurttemberg, Germany) · May 2026 Biological organization has traditionally been viewed through the lens of distinct organelles and lock-and-key molecular interactions. The recent explosion of interest in phase separation has reshaped this view, revealing that cells also organize through m ... Full text CiteGenetically Encoded Sterol-Modification of a Synthetic Intrinsically Disordered Protein Drives Its Self-Assembly Into Diverse Morphologies.
Journal Article Small (Weinheim an der Bergstrasse, Germany) · April 2026 Post-translational modifications (PTMs) of proteins are used by natural systems to expand beyond the 20 canonical amino acids. The variation introduced at the sequence level by PTMs after expression leads to changes in both the structure and function of pr ... Full text CiteAll-PEG-Like Block Copolymers Self-Assemble into Stealth Nanocarriers for Drug Delivery.
Journal Article Advanced science (Weinheim, Baden-Wurttemberg, Germany) · March 2026 Poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) is a stealth polymer that does not exhibit polyethylene glycol (PEG) antigenicity. Herein, we engineered self-assembling nanoparticles composed entirely of POEGMA by designing AB diblock copol ... Full text CiteRecent Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030Breast Cancer Diagnostic Kit to Improve Early Diagnosis in Uganda
ResearchPrincipal Investigator · Awarded by Vanderbilt University Medical Center · 2024 - 2029Biosynthesis of Therapeutic Peptides for Pediatric Cancers with Undruggable Drivers
ResearchCollaborator · Awarded by Hartwell Foundation · 2026 - 2029View All Grants
Education
University of Washington ·
1991
Ph.D.