Overview
Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University.
My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.
Current Appointments & Affiliations
Alan L. Kaganov Distinguished Professor of Biomedical Engineering
·
2016 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor of Biomedical Engineering
·
2006 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor in the Department of Chemistry
·
2009 - Present
Chemistry,
Trinity College of Arts & Sciences
Research Professor of Global Health
·
2020 - Present
Duke Global Health Institute,
University Institutes and Centers
Member of the Duke Cancer Institute
·
1996 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer.
Journal Article Adv Sci (Weinh) · October 2025 Biomaterials can improve cancer immunotherapies by controlling their release and thereby optimizing their time-dependent engagement of the immune system. In this study, an approach is described to control the release of a potent immunostimulant-CpG oligode ... Full text Link to item CiteRational Design of Thermoresponsive Elastin-Like Protein Monolayers for Nonenzymatic Cell Harvesting.
Journal Article Biomacromolecules · September 2025 A combined theoretical and experimental investigation presents a consistent parabolic potential model for the prediction and optimization of mammalian cell adhesion and detachment from genetically engineered thermoresponsive elastin-like protein (ELP) modi ... Full text CiteNonfouling Coatings from Synthetic Intrinsically Disordered Proteins.
Journal Article Small (Weinheim an der Bergstrasse, Germany) · August 2025 The antifouling performance of a previously developed triblock protein, B-M-E is optimized, that self-assembles on gold surfaces to form a nonfouling layer by modifying the sequence of its E block. In this protein, B is a gold-binding domain, M is a trimer ... Full text CiteRecent Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030Breast Cancer Diagnostic Kit to Improve Early Diagnosis in Uganda
ResearchPrincipal Investigator · Awarded by Vanderbilt University Medical Center · 2024 - 2029Development, Clinical Validation, and Readiness for Implementation of a Novel Mp1p D4 Point of Care Test for Rapid Diagnosis of Talaromycosis
ResearchCo-Principal Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028View All Grants
Education, Training & Certifications
University of Washington ·
1991
Ph.D.