Skip to main content

Fourier domain multispectral multiple scattering low coherence interferometry.

Publication ,  Journal Article
Matthews, TE; Giacomelli, MG; Brown, WJ; Wax, A
Published in: Applied optics
December 2013

We have implemented multispectral multiple scattering low coherence interferometry (ms2/LCI) with Fourier domain data collection. The ms2/LCI system is designed to localize features with spectroscopic contrast with millimeter resolution up to 1 cm deep in scattering samples by using photons that have undergone multiple low-angle (forward) scattering events. Fourier domain detection both increases the data acquisition speed of the system and gives access to rich spectroscopic information, compared to the previous single channel, time-domain implementation. Separate delivery and detection angular apertures reduce collection of the diffuse background signal in order to isolate localized spectral features from deeper in scattering samples than would be possible with traditional spectroscopic optical coherence tomography. Light from a supercontinuum source is used to acquire absorption spectra of chromophores in the visible range within a tissue-like scattering phantom. An intensity modulation and digital lock-in detection scheme is implemented to mitigate relative intensity and spectral noise inherent in supercontinuum sources. The technical parameters of the system and comparative analysis are presented.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Applied optics

DOI

EISSN

1539-4522

ISSN

1559-128X

Publication Date

December 2013

Volume

52

Issue

34

Start / End Page

8220 / 8228

Related Subject Headings

  • Spectrum Analysis
  • Scattering, Radiation
  • Refractometry
  • Optics
  • Nephelometry and Turbidimetry
  • Light
  • Interferometry
  • Fourier Analysis
  • Equipment Failure Analysis
  • Equipment Design
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Matthews, T. E., Giacomelli, M. G., Brown, W. J., & Wax, A. (2013). Fourier domain multispectral multiple scattering low coherence interferometry. Applied Optics, 52(34), 8220–8228. https://doi.org/10.1364/ao.52.008220
Matthews, Thomas E., Michael G. Giacomelli, William J. Brown, and Adam Wax. “Fourier domain multispectral multiple scattering low coherence interferometry.Applied Optics 52, no. 34 (December 2013): 8220–28. https://doi.org/10.1364/ao.52.008220.
Matthews TE, Giacomelli MG, Brown WJ, Wax A. Fourier domain multispectral multiple scattering low coherence interferometry. Applied optics. 2013 Dec;52(34):8220–8.
Matthews, Thomas E., et al. “Fourier domain multispectral multiple scattering low coherence interferometry.Applied Optics, vol. 52, no. 34, Dec. 2013, pp. 8220–28. Epmc, doi:10.1364/ao.52.008220.
Matthews TE, Giacomelli MG, Brown WJ, Wax A. Fourier domain multispectral multiple scattering low coherence interferometry. Applied optics. 2013 Dec;52(34):8220–8228.

Published In

Applied optics

DOI

EISSN

1539-4522

ISSN

1559-128X

Publication Date

December 2013

Volume

52

Issue

34

Start / End Page

8220 / 8228

Related Subject Headings

  • Spectrum Analysis
  • Scattering, Radiation
  • Refractometry
  • Optics
  • Nephelometry and Turbidimetry
  • Light
  • Interferometry
  • Fourier Analysis
  • Equipment Failure Analysis
  • Equipment Design