Adam P. Wax
Professor of Biomedical Engineering
Dr. Wax's research interests include optical spectroscopy for early cancer detection, novel microscopy and interferometry techniques.
The study of intact, living cells with optical spectroscopy offers the opportunity to observe cellular structure, organization and dynamics in a way that is not possible with traditional methods. We have developed a set of novel spectroscopic techniques for measuring spatial, temporal and refractive structure on sub-hertz and sub-wavelength scales based on using low-coherence interferometry (LCI) to detect scattered light. We have applied these techniques in different types of cell biology experiments. In one experiment, LCI measurements of the angular pattern of backscattered light are used to determine non-invasively the structure of sub-cellular organelles in cell monolayers, and the components of epithelial tissue from freshly excised rat esophagus. This work has potential as a diagnostic method for early cancer detection. In another experiment, LCI phase measurements are used to examine volume changes of epithelial cells in a monolayer in response to environmental osmolarity changes. Although cell volume changes have been measured previously, this work demonstrates for the first time the volume of just a few cells (2 or 3) tracked continuously and in situ.
Current Research Interests
Current Appointments & Affiliations
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2013
- Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2012
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017
- Bass Fellow, Biomedical Engineering, Pratt School of Engineering 2016
Contact Information
- 2571 CIEMAS, Durham, NC 27708
- Box 90281, Durham, NC 27708-0281
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a.wax@duke.edu
(919) 660-5143
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Google Scholar
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http://bios.bme.duke.edu
- Background
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Education, Training, & Certifications
- Ph.D., Duke University 1999
- M.A., Duke University 1996
- B.S., Rensselaer Polytechnic Institute 1993
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Previous Appointments & Affiliations
- Professor of Physics, Physics, Trinity College of Arts & Sciences 2018 - 2021
- Director of Graduate Studies, Biomedical Engineering, Pratt School of Engineering 2013 - 2016
- Theodore Kennedy Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2013 - 2016
- Associate Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2008 - 2013
- Theodore Kennedy Associate Professor, Biomedical Engineering, Pratt School of Engineering 2011 - 2013
- Director of Graduate Studies in Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2010 - 2011
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2002 - 2008
- Recognition
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In the News
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DEC 3, 2021 Pratt School of Engineering -
DEC 1, 2021 Pratt School of Engineering -
MAY 22, 2020 Pratt School of Engineering -
NOV 15, 2019 Pratt School of Engineering -
JUL 1, 2019 Pratt School of Engineering -
MAR 2, 2017 Pratt School of Engineering -
SEP 16, 2016
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Awards & Honors
- Expertise
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Subject Headings
- Anemia, Sickle Cell
- Biomechanical Phenomena
- Biomedical Engineering
- Biophysics
- Biopsy
- Biosensing Techniques
- Burns
- Carcinogens
- Cartilage, Articular
- Cell Differentiation
- Cell Nucleus
- Cell Nucleus Size
- Cell Size
- Cell Transformation, Neoplastic
- Cells, Cultured
- Chromatin
- Computer Simulation
- Diagnostic Imaging
- Disease Models, Animal
- Early Detection of Cancer
- Emulsions
- Epithelial Cells
- Equipment Design
- Erythrocytes
- Erythrocytes, Abnormal
- Esophageal Neoplasms
- Esophagus
- Fiber Optic Technology
- Fourier Analysis
- Fractals
- Gels
- Image Interpretation, Computer-Assisted
- Interferometry
- Intestines
- Light
- Metal Nanoparticles
- Mice
- Microscopy
- Microscopy, Electron, Transmission
- Microscopy, Fluorescence
- Microscopy, Interference
- Microspheres
- Molecular Imaging
- Mucous Membrane
- Muscle, Skeletal
- Nanoparticles
- Nanotechnology
- Neoplasms, Experimental
- Nonlinear Dynamics
- Optical Imaging
- Optical Phenomena
- Optical coherence tomography
- Particle Size
- Phantoms, Imaging
- Phospholipids
- Photons
- Polymers
- Precancerous Conditions
- Receptor, Epidermal Growth Factor
- Receptors, Cell Surface
- Refractometry
- Scattering, Radiation
- Signal Processing, Computer-Assisted
- Skin
- Spectrum Analysis
- Staining and Labeling
- Stem Cells
- Surface Plasmon Resonance
- Surface Properties
- Tissue Culture Techniques
- Tomography, Optical Coherence
- Tumor Cells, Cultured
- Vaginal Creams, Foams, and Jellies
- Research
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Selected Grants
- Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease awarded by National Institutes of Health 2022 - 2027
- Title: NRT-FW-HTF: NSF Traineeship in the Advancement of Surgical Technologies awarded by National Science Foundation 2021 - 2026
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2023
- Angle resolved light scattering through a multimode fiber for measuring cell nuclei morphology awarded by National Science Foundation 2020 - 2023
- Low cost OCT probe for GI applications 2021 - 2022
- Advanced a/LCI systems for improved clinical utility awarded by National Institutes of Health 2016 - 2022
- Using AI to develop a red blood cell health index for the monitoring of sickle cell disease 2021 - 2022
- Analysis of mechanical induction of bioelectric activity in cells awarded by Army Research Office 2019 - 2022
- Novel Coherence Imaging to Evaluate the Health of the Cervical Epithelium awarded by National Institutes of Health 2014 - 2021
- High throughput cell screening for toxic metal exposure awarded by National Institutes of Health 2018 - 2020
- Deep skin imaging with OCT awarded by National Science Foundation 2018 - 2020
- Training in Medical Imaging awarded by National Institutes of Health 2003 - 2020
- Coherent light scattering for early detection of Alzheimer's disease awarded by National Institutes of Health 2017 - 2020
- Visualization of mechanical stress in live cells awarded by National Science Foundation 2016 - 2019
- Improving Medical Outcomes Through Needle-Based Optical Sensing 2015 - 2017
- Novel Determination of Microbicide PK in Women's Reproductive Health awarded by National Institutes of Health 2012 - 2017
- EAGER: Cell phone enabled spectroscopy awarded by National Science Foundation 2014 - 2016
- Coherent light scattering for early detection of retinal disease awarded by National Institutes of Health 2013 - 2016
- Inhibition of Reflux-Induced Esophageal Adenocarcinoma by Proanthocyanidins awarded by Medical College of Wisconsin 2013 - 2016
- InCh Microscope: Compact and Portable Quantitative Phase Microscope for Label-Free Morphological Diagnosis of Blood Samp 2014
- Increased Depth Penetration in Coherence Imaging Using Multiply Scattered Light awarded by National Science Foundation 2011 - 2014
- MRI: Development of a Hybrid Quantitative Phase Microscope for Live Cell Imaging awarded by National Science Foundation 2010 - 2014
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- I-Corps: InCh holographic microscope for cell diagnostics awarded by National Science Foundation 2012
- Coherence Imaging for Assessing Colorectal Neoplasia awarded by National Institutes of Health 2009 - 2012
- Molecular Imaging Using Hyperspectral Darkfield Microscope of Nanoparticles awarded by National Science Foundation 2007 - 2011
- Assessing Deployment of Microbicidal Gels With Label-Free Optical Measurement awarded by National Institutes of Health 2007 - 2010
- In Vivo Detection of Pre-Cancerous Lesions Using a /LCI awarded by National Institutes of Health 2004 - 2010
- Low Coherence Light Scattering for Biophotonics awarded by National Science Foundation 2005 - 2010
- CAREER: Low Coherence Light Scattering for Biophotonics awarded by National Science Foundation 2004 - 2009
- Assessing Nuclear Morphology in Thick Tissues Using fLCI awarded by National Institutes of Health 2006 - 2008
- In Vivo Detection of Pre-Cancerous Lesions Using a/LCI awarded by National Institutes of Health 2004 - 2006
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External Relationships
- Lumedica
- Lumedica Vision
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Chu, Kengyeh K., Yang Zhao, Evan T. Jelly, Zachary A. Steelman, Michael Crose, Brian Cox, Yaa Ofori-Marfoh, et al. “Esophageal OCT Imaging Using a Paddle Probe Externally Attached to Endoscope.” Digestive Diseases and Sciences 67, no. 10 (October 2022): 4805–12. https://doi.org/10.1007/s10620-021-07372-w.Full Text
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Jelly, Evan T., Yang Zhao, Kengyeh K. Chu, Hillel Price, Michael Crose, Zachary A. Steelman, and Adam Wax. “Deep imaging with 1.3 µm dual-axis optical coherence tomography and an enhanced depth of focus.” Biomedical Optics Express 12, no. 12 (December 2021): 7689–7702. https://doi.org/10.1364/boe.438621.Full Text
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Chen, C. X., H. S. Park, H. Price, and A. Wax. “Automated Classification of Breast Cancer Cells Using High-Throughput Holographic Cytometry.” Frontiers in Physics 9 (November 30, 2021). https://doi.org/10.3389/fphy.2021.759142.Full Text
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Yang, Ziyun, Somayyeh Soltanian-Zadeh, Kengyeh K. Chu, Haoran Zhang, Lama Moussa, Ariel E. Watts, Nicholas J. Shaheen, Adam Wax, and Sina Farsiu. “Connectivity-based deep learning approach for segmentation of the epithelium in in vivo human esophageal OCT images.” Biomedical Optics Express 12, no. 10 (October 2021): 6326–40. https://doi.org/10.1364/boe.434775.Full Text
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Park, Han-Sang, Hillel Price, Silvia Ceballos, Jen-Tsan Chi, and Adam Wax. “Single Cell Analysis of Stored Red Blood Cells Using Ultra-High Throughput Holographic Cytometry.” Cells 10, no. 9 (September 17, 2021). https://doi.org/10.3390/cells10092455.Full Text Link to Item
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Jelly, Evan T., Jean Kwun, Robin Schmitz, Alton B. Farris, Zachary A. Steelman, Debra L. Sudan, Stuart J. Knechtle, and Adam Wax. “Optical coherence tomography of small intestine allograft biopsies using a handheld surgical probe.” J Biomed Opt 26, no. 9 (September 2021). https://doi.org/10.1117/1.JBO.26.9.096008.Full Text Link to Item
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Zhang, Haoran, Wesley Y. Kendall, Evan T. Jelly, and Adam Wax. “Deep learning classification of cervical dysplasia using depth-resolved angular light scattering profiles.” Biomedical Optics Express 12, no. 8 (August 2021): 4997–5007. https://doi.org/10.1364/boe.430467.Full Text
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Song, Ge, Evan T. Jelly, Ken Chu, Wesley Y. Kendall, and Adam Wax. “A review of low-cost and portable optical coherence tomography.” Progress in Biomedical Engineering, 2021.
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Kendall, Wesley Y., Derek Ho, Kengyeh Chu, Michael Zinaman, Daryl Wieland, Kandis Moragne, and Adam Wax. “Prospective detection of cervical dysplasia with scanning angle-resolved low coherence interferometry.” Biomedical Optics Express 11, no. 9 (September 2020): 5197–5211. https://doi.org/10.1364/boe.401000.Full Text
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Song, Ge, Zachary A. Steelman, Wesley Kendall, Han Sang Park, and Adam Wax. “Spatial scanning of a sample with two-dimensional angle-resolved low-coherence interferometry for analysis of anisotropic scatterers.” Biomedical Optics Express 11, no. 8 (August 2020): 4419–30. https://doi.org/10.1364/boe.398052.Full Text
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Zhang, H., Z. A. Steelman, S. Ceballos, K. K. Chu, and A. Wax. “Reconstruction of angle-resolved backscattering through a multimode fiber for cell nuclei and particle size determination.” Apl Photonics 5, no. 7 (July 1, 2020). https://doi.org/10.1063/5.0011500.Full Text
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Song, Ge, Zachary A. Steelman, Stella Finkelstein, Ziyun Yang, Ludovic Martin, Kengyeh K. Chu, Sina Farsiu, Vadim Y. Arshavsky, and Adam Wax. “Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model.” Sci Rep 10, no. 1 (May 13, 2020): 7912. https://doi.org/10.1038/s41598-020-64827-2.Full Text Link to Item
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Zhao, Yang, Kengyeh K. Chu, Evan T. Jelly, and Adam Wax. “Origin of improved depth penetration in dual-axis optical coherence tomography: a Monte Carlo study (vol 12, e201800383, 2019).” Journal of Biophotonics 13 (2020).
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Muñoz, Alexandra, Will J. Eldridge, Nina Munkholt Jakobsen, Helle Sørensen, Adam Wax, and Max Costa. “Corrigendum: Cellular shear stiffness reflects progression of arsenic-induced transformation during G1.” Carcinogenesis 40, no. 10 (October 2019): 1298. https://doi.org/10.1093/carcin/bgz048.Full Text
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Eldridge, Will J., Silvia Ceballos, Tejank Shah, Han Sang Park, Zachary A. Steelman, Stefan Zauscher, and Adam Wax. “Shear Modulus Measurement by Quantitative Phase Imaging and Correlation with Atomic Force Microscopy.” Biophysical Journal 117, no. 4 (August 2019): 696–705. https://doi.org/10.1016/j.bpj.2019.07.008.Full Text
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Steelman, Zachary A., Derek S. Ho, Kengyeh K. Chu, and Adam Wax. “Light scattering methods for tissue diagnosis.” Optica 6, no. 4 (April 2019): 479–89. https://doi.org/10.1364/optica.6.000479.Full Text Open Access Copy
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Zhang, Haoran, Zachary A. Steelman, Derek S. Ho, Kengyeh K. Chu, and Adam Wax. “Angular range, sampling and noise considerations for inverse light scattering analysis of nuclear morphology.” Journal of Biophotonics 12, no. 2 (February 2019): e201800258. https://doi.org/10.1002/jbio.201800258.Full Text
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Song, Ge, Kengyeh K. Chu, Sanghoon Kim, Michael Crose, Brian Cox, Evan T. Jelly, J Niklas Ulrich, and Adam Wax. “First clinical application of low-cost OCT.” Translational Vision Science & Technology 8 (2019): 61–61.
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Jelly, Evan T., Zachary A. Steelman, and Adam Wax. “Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model.” Optics Letters 44 (2019): 5590–93.
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Park, Han Sang, Will J. Eldridge, Wen-Hsuan Yang, Michael Crose, Silvia Ceballos, John D. Roback, Jen-Tsan Ashley Chi, and Adam Wax. “Quantitative phase imaging of erythrocytes under microfluidic constriction in a high refractive index medium reveals water content changes.” Microsyst Nanoeng 5 (2019): 63. https://doi.org/10.1038/s41378-019-0113-y.Full Text Open Access Copy Link to Item
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Zhao, Yang, Kengyeh K. Chu, Evan T. Jelly, and Adam Wax. “Origin of improved depth penetration in dual-axis optical coherence tomography: a Monte Carlo study.” Journal of Biophotonics 12 (2019): e201800383–e201800383.
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Eldridge, Will J., Jawad Hoballah, and Adam Wax. “Molecular and biophysical analysis of apoptosis using a combined quantitative phase imaging and fluorescence resonance energy transfer microscope.” Journal of Biophotonics 11, no. 12 (December 2018): e201800126. https://doi.org/10.1002/jbio.201800126.Full Text
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Park, Han Sang, Silvia Ceballos, Will J. Eldridge, and Adam Wax. “Invited Article: Digital refocusing in quantitative phase imaging for flowing red blood cells.” Apl Photonics 3, no. 11 (November 2018): 110802. https://doi.org/10.1063/1.5043536.Full Text
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Wax, A. “Oct promising as clear point-of-care solution.” Biophotonics International 25, no. 6 (September 1, 2018): 30–33.
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Steelman, Zachary A., Will J. Eldridge, and Adam Wax. “Response to Comment on "Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies": A Comment on "How a phase image of a cell with nucleus refractive index smaller than that of the cytoplasm should look like?", e201800033.” Journal of Biophotonics 11, no. 6 (June 2018): e201800091. https://doi.org/10.1002/jbio.201800091.Full Text
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Kim, Sanghoon, Michael Crose, Will J. Eldridge, Brian Cox, William J. Brown, and Adam Wax. “Design and implementation of a low-cost, portable OCT system.” Biomedical Optics Express 9, no. 3 (March 2018): 1232–43. https://doi.org/10.1364/boe.9.001232.Full Text
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Zhou, Y., Y. Zhao, S. Kim, and A. Wax. “Spectroscopic OCT: Towards an effective tool for distinguishing authentic and artificial Chinese freshwater pearls.” Optical Materials Express 8, no. 3 (March 1, 2018): 622–28. https://doi.org/10.1364/OME.8.000622.Full Text
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Muñoz, Alexandra, Will J. Eldridge, Nina Munkholt Jakobsen, Helle Sørensen, Adam Wax, and Max Costa. “Cellular shear stiffness reflects progression of arsenic-induced transformation during G1.” Carcinogenesis 39, no. 2 (February 2018): 109–17. https://doi.org/10.1093/carcin/bgx116.Full Text
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Zhao, Yang, Kengyeh K. Chu, Will J. Eldridge, Evan T. Jelly, Michael Crose, and Adam Wax. “Real-time speckle reduction in optical coherence tomography using the dual window method.” Biomedical Optics Express 9 (2018): 616–22.
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Steelman, Zachary A., Sanghoon Kim, Evan T. Jelly, Michael Crose, Kengyeh K. Chu, and Adam Wax. “Comparison of imaging fiber bundles for coherence-domain imaging.” Applied Optics 57 (2018): 1455–62.
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Chowdhury, Shwetadwip, Will J. Eldridge, Adam Wax, and Joseph A. Izatt. “Structured illumination microscopy for dual-modality 3D sub-diffraction resolution fluorescence and refractive-index reconstruction.” Biomedical Optics Express 8, no. 12 (December 2017): 5776–93. https://doi.org/10.1364/boe.8.005776.Full Text
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Steelman, Zachary A., Will J. Eldridge, Jacob B. Weintraub, and Adam Wax. “Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies.” Journal of Biophotonics 10, no. 12 (December 2017): 1714–22. https://doi.org/10.1002/jbio.201600314.Full Text
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Steelman, Zachary A., Derek Ho, Kengyeh K. Chu, and Adam Wax. “Scanning system for angle-resolved low-coherence interferometry.” Optics Letters 42, no. 22 (November 2017): 4581–84. https://doi.org/10.1364/ol.42.004581.Full Text
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Minzioni, P., R. Osellame, C. Sada, S. Zhao, F. G. Omenetto, K. B. Gylfason, T. Haraldsson, et al. “Roadmap for optofluidics.” Journal of Optics (United Kingdom) 19, no. 9 (August 22, 2017). https://doi.org/10.1088/2040-8986/aa783b.Full Text
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Zhao, Yang, Will J. Eldridge, Jason R. Maher, Sanghoon Kim, Michael Crose, Mohamed Ibrahim, Howard Levinson, and Adam Wax. “Dual-axis optical coherence tomography for deep tissue imaging.” Opt Lett 42, no. 12 (June 15, 2017): 2302–5. https://doi.org/10.1364/OL.42.002302.Full Text Link to Item
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Chowdhury, S., W. J. Eldridge, A. Wax, and J. Izatt. “Refractive index tomography with structured illumination.” Optica 4, no. 5 (May 20, 2017): 537–45. https://doi.org/10.1364/OPTICA.4.000537.Full Text
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Chowdhury, Shwetadwip, Will J. Eldridge, Adam Wax, and Joseph A. Izatt. “Structured illumination multimodal 3D-resolved quantitative phase and fluorescence sub-diffraction microscopy.” Biomedical Optics Express 8, no. 5 (May 2017): 2496–2518. https://doi.org/10.1364/boe.8.002496.Full Text
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Ho, Derek, Tyler K. Drake, Karen K. Smith-McCune, Teresa M. Darragh, Loris Y. Hwang, and Adam Wax. “Feasibility of clinical detection of cervical dysplasia using angle-resolved low coherence interferometry measurements of depth-resolved nuclear morphology.” International Journal of Cancer 140, no. 6 (March 2017): 1447–56. https://doi.org/10.1002/ijc.30539.Full Text
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Chuchuen, Oranat, Jason R. Maher, Morgan G. Simons, Jennifer J. Peters, Adam P. Wax, and David F. Katz. “Label-Free Measurements of Tenofovir Diffusion Coefficients in a Microbicide Gel Using Raman Spectroscopy.” Journal of Pharmaceutical Sciences 106, no. 2 (February 2017): 639–44. https://doi.org/10.1016/j.xphs.2016.09.030.Full Text
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Eldridge, Will J., Zachary A. Steelman, Brianna Loomis, and Adam Wax. “Optical Phase Measurements of Disorder Strength Link Microstructure to Cell Stiffness.” Biophysical Journal 112, no. 4 (February 2017): 692–702. https://doi.org/10.1016/j.bpj.2016.12.016.Full Text
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Chuchuen, Oranat, Jason R. Maher, Marcus H. Henderson, Michael Desoto, Lisa C. Rohan, Adam Wax, and David F. Katz. “Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography.” Plos One 12, no. 9 (January 2017): e0185633. https://doi.org/10.1371/journal.pone.0185633.Full Text
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Wax, Adam. “Advances in functional OCT.” Laser Focus World 53, no. 1 (January 1, 2017): 66–71.Link to Item
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Zhao, Yang, Jason R. Maher, Mohamed M. Ibrahim, Jennifer S. Chien, Howard Levinson, and Adam Wax. “Deep imaging of absorption and scattering features by multispectral multiple scattering low coherence interferometry.” Biomed Opt Express 7, no. 10 (October 1, 2016): 3916–26. https://doi.org/10.1364/BOE.7.003916.Full Text Link to Item
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Wax, A., and K. Chu. “Found in translation: Biophotonics from lab to clinic.” Optics and Photonics News 27, no. 9 (September 1, 2016): 34–41. https://doi.org/10.1364/OPN.27.9.000034.Full Text
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Rinehart, Matthew T., Han Sang Park, Katelyn A. Walzer, Jen-Tsan Ashley Chi, and Adam Wax. “Hemoglobin consumption by P. falciparum in individual erythrocytes imaged via quantitative phase spectroscopy.” Sci Rep 6 (April 18, 2016): 24461. https://doi.org/10.1038/srep24461.Full Text Link to Item
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Kim, Sanghoon, Stephanie Heflin, Laura A. Kresty, Meredith Halling, Laura N. Perez, Derek Ho, Michael Crose, et al. “Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography.” Biomed Opt Express 7, no. 4 (April 1, 2016): 1400–1414. https://doi.org/10.1364/BOE.7.001400.Full Text Link to Item
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Eldridge, Will J., Adi Sheinfeld, Matthew T. Rinehart, and Adam Wax. “Imaging deformation of adherent cells due to shear stress using quantitative phase imaging.” Optics Letters 41, no. 2 (January 2016): 352–55. https://doi.org/10.1364/ol.41.000352.Full Text
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Park, Han Sang, Matthew T. Rinehart, Katelyn A. Walzer, Jen-Tsan Ashley Chi, and Adam Wax. “Automated Detection of P. falciparum Using Machine Learning Algorithms with Quantitative Phase Images of Unstained Cells.” Plos One 11, no. 9 (2016): e0163045. https://doi.org/10.1371/journal.pone.0163045.Full Text Open Access Copy Link to Item
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Zhao, Yang, Jason R. Maher, Jina Kim, Maria Angelica Selim, Howard Levinson, and Adam Wax. “Evaluation of burn severity in vivo in a mouse model using spectroscopic optical coherence tomography.” Biomed Opt Express 6, no. 9 (September 1, 2015): 3339–45. https://doi.org/10.1364/BOE.6.003339.Full Text Link to Item
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Sheinfeld, Adi, Will J. Eldridge, and Adam Wax. “Quantitative phase imaging with molecular sensitivity using photoacoustic microscopy with a miniature ring transducer.” Journal of Biomedical Optics 20, no. 8 (August 2015): 86002. https://doi.org/10.1117/1.jbo.20.8.086002.Full Text
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Ho, Derek, Tyler K. Drake, Rex C. Bentley, Fidel A. Valea, and Adam Wax. “Evaluation of hybrid algorithm for analysis of scattered light using ex vivo nuclear morphology measurements of cervical epithelium.” Biomed Opt Express 6, no. 8 (August 1, 2015): 2755–65. https://doi.org/10.1364/BOE.6.002755.Full Text Link to Item
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Maher, Jason R., Oranat Chuchuen, Marcus H. Henderson, Sanghoon Kim, Matthew T. Rinehart, Angela D. M. Kashuba, Adam Wax, and David F. Katz. “Co-localized confocal Raman spectroscopy and optical coherence tomography (CRS-OCT) for depth-resolved analyte detection in tissue.” Biomedical Optics Express 6, no. 6 (June 2015): 2022–35. https://doi.org/10.1364/boe.6.002022.Full Text
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Rinehart, Matthew T., Han Sang Park, and Adam Wax. “Influence of defocus on quantitative analysis of microscopic objects and individual cells with digital holography.” Biomedical Optics Express 6, no. 6 (June 2015): 2067–75. https://doi.org/10.1364/boe.6.002067.Full Text
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Kim, Jina, William Brown, Jason R. Maher, Howard Levinson, and Adam Wax. “Functional optical coherence tomography: principles and progress.” Phys Med Biol 60, no. 10 (May 21, 2015): R211–37. https://doi.org/10.1088/0031-9155/60/10/R211.Full Text Link to Item
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Chowdhury, Shwetadwip, Will J. Eldridge, Adam Wax, and Joseph A. Izatt. “Spatial frequency-domain multiplexed microscopy for simultaneous, single-camera, one-shot, fluorescent, and quantitative-phase imaging.” Optics Letters 40 (2015): 4839–42.
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Brown, William J., Sanghoon Kim, and Adam Wax. “Noise characterization of supercontinuum sources for low-coherence interferometry applications.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 31, no. 12 (December 2014): 2703–10. https://doi.org/10.1364/josaa.31.002703.Full Text
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Ho, Derek, Sanghoon Kim, Tyler K. Drake, Will J. Eldridge, and Adam Wax. “Wavelet transform fast inverse light scattering analysis for size determination of spherical scatterers.” Biomedical Optics Express 5, no. 10 (October 2014): 3292–3304. https://doi.org/10.1364/boe.5.003292.Full Text
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Maher, Jason R., Volker Jaedicke, Manuel Medina, Howard Levinson, Maria Angelica Selim, William J. Brown, and Adam Wax. “In vivo analysis of burns in a mouse model using spectroscopic optical coherence tomography.” Opt Lett 39, no. 19 (October 1, 2014): 5594–97. https://doi.org/10.1364/OL.39.005594.Full Text Link to Item
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Eldridge, Will J., Amihai Meiri, Adi Sheinfeld, Matthew T. Rinehart, and Adam Wax. “Fast wide-field photothermal and quantitative phase cell imaging with optical lock-in detection.” Biomedical Optics Express 5, no. 8 (August 2014): 2517–25. https://doi.org/10.1364/boe.5.002517.Full Text
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Rinehart, Matthew T., Volker Jaedicke, and Adam Wax. “Quantitative phase microscopy with off-axis optical coherence tomography.” Optics Letters 39, no. 7 (April 2014): 1996–99. https://doi.org/10.1364/ol.39.001996.Full Text
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Maher, Jason R., Thomas E. Matthews, Ashley K. Reid, David F. Katz, and Adam Wax. “Sensitivity of coded aperture Raman spectroscopy to analytes beneath turbid biological tissue and tissue-simulating phantoms.” Journal of Biomedical Optics 19, no. 11 (January 2014): 117001. https://doi.org/10.1117/1.jbo.19.11.117001.Full Text
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Matthews, T. E., M. Medina, J. R. Maher, H. Levinson, W. J. Brown, and A. Wax. “Deep tissue imaging using spectroscopic analysis of multiply scattered light.” Optica 1, no. 2 (January 1, 2014): 105–11. https://doi.org/10.1364/OPTICA.1.000105.Full Text
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Rinehart, Matthew, Sheila Grab, Lisa Rohan, David Katz, and Adam Wax. “Analysis of vaginal microbicide film hydration kinetics by quantitative imaging refractometry.” Plos One 9, no. 4 (January 2014): e95005. https://doi.org/10.1371/journal.pone.0095005.Full Text
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Sun, Z., S. Shan, H. Sang, J. Zhou, Y. Wang, and W. Yuan. “Preface.” Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 8833 (January 1, 2014). https://doi.org/10.1007/978-3-319-12484-1.Full Text
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Matthews, Thomas E., Michael G. Giacomelli, William J. Brown, and Adam Wax. “Fourier domain multispectral multiple scattering low coherence interferometry.” Applied Optics 52, no. 34 (December 2013): 8220–28. https://doi.org/10.1364/ao.52.008220.Full Text
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Yarmoska, S. K., S. Kim, M. G. Giacomelli, and A. Wax. “A calibration standard for two-dimensional angle-resolved low-coherence interferometry.” Optical Trapping Applications, Ota 2013, November 21, 2013.
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Yarmoska, S. K., S. Kim, M. G. Giacomelli, and A. Wax. “A calibration standard for two-dimensional angle-resolved low-coherence interferometry.” Bio Optics: Design and Application, Boda 2013, November 18, 2013.
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Zhu, Y., M. T. Rinehart, F. E. Robles, and A. Wax. “Polarization and Spectral Interferometric Techniques for Quantitative Phase Microscopy,” August 27, 2013, 218–310. https://doi.org/10.1016/B978-0-12-415871-9.00014-4.Full Text
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Drake, Tyler K., Tejen Shah, Jennifer J. Peters, Adam Wax, and David F. Katz. “Measuring dilution of microbicide gels with optical imaging.” Plos One 8, no. 12 (January 2013): e82213. https://doi.org/10.1371/journal.pone.0082213.Full Text
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Matthews, T. E., O. Chuchuen, D. F. Katz, and A. Wax. “Multimodal multiplex raman spectroscopy and optical coherence tomography of tissue for drug monitoring.” Optical Molecular Probes, Imaging and Drug Delivery, Omp 2013, January 1, 2013. https://doi.org/10.1364/omp.2013.mt1c.2.Full Text
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Skala, Melissa C., Matthew J. Crow, Adam Wax, and Joseph A. Izatt. “Three-dimensional molecular imaging with photothermal optical coherence tomography.” Methods in Molecular Biology (Clifton, N.J.) 1026 (January 2013): 85–92. https://doi.org/10.1007/978-1-62703-468-5_7.Full Text
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Wax, A. “Plasmonic nanoparticles as molecular contrast agents in interferometric imaging.” Optical Molecular Probes, Imaging and Drug Delivery, Omp 2013, January 1, 2013. https://doi.org/10.1364/omp.2013.mw1c.2.Full Text
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Wax, A. “Wigner distribution: Friend to biophotonics.” Optics Infobase Conference Papers, January 1, 2013.
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Wax, Adam, Amihai Meiri, Siddarth Arumugam, and Matthew T. Rinehart. “Comparative review of interferometric detection of plasmonic nanoparticles.” Biomedical Optics Express 4, no. 10 (January 2013): 2166–78. https://doi.org/10.1364/boe.4.002166.Full Text
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Wax, Adam, and Kevin J. Chalut. “Nuclear morphology measurements with angle-resolved low coherence interferometry for application to cell biology and early cancer detection.” Studies in Health Technology and Informatics 185 (January 2013): 129–51.
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Yarmoska, S. K., S. Kim, M. G. Giacomelli, and A. Wax. “A calibration standard for two-dimensional angle-resolved low-coherence interferometry.” Optical Molecular Probes, Imaging and Drug Delivery, Omp 2013, January 1, 2013. https://doi.org/10.1364/boda.2013.jt2a.10.Full Text
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Yarmoska, Steven K., Sanghoon Kim, Thomas E. Matthews, and Adam Wax. “A scattering phantom for observing long range order with two-dimensional angle-resolved Low-Coherence Interferometry.” Biomedical Optics Express 4, no. 9 (January 2013): 1742–48. https://doi.org/10.1364/boe.4.001742.Full Text
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Seekell, K., S. Lewis, C. Wilson, G. Grant, and A. Wax. “Feasibility of brain tumor delineation using immunolabeled gold nanorods.” Optical Molecular Probes, Imaging and Drug Delivery, Omp 2013, January 1, 2013. https://doi.org/10.1364/omp.2013.mw1c.3.Full Text
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Seekell, Kevin, Spencer Lewis, Christy Wilson, Shuqin Li, Gerald Grant, and Adam Wax. “Feasibility study of brain tumor delineation using immunolabeled gold nanorods.” Biomed Opt Express 4, no. 11 (2013): 2284–95. https://doi.org/10.1364/BOE.4.002284.Full Text Link to Item
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Kim, S., M. T. Rinehart, Y. Zhu, and A. Wax. “Spectrally multiplexed photothermal OCT and novel detection methods.” 2012 Conference on Lasers and Electro Optics, Cleo 2012, December 6, 2012.
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Wax, A. “Coherence imaging for early cancer detection.” 2012 Conference on Lasers and Electro Optics, Cleo 2012, December 6, 2012.
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Kim, S., M. T. Rinehart, Y. Zhu, and A. Wax. “Spectrally multiplexed photothermal OCT and novel detection methods.” Cleo: Applications and Technology, Cleo at 2012, December 1, 2012.
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Kim, S., M. T. Rinehart, Y. Zhu, and A. Wax. “Spectrally multiplexed photothermal OCT and novel detection methods.” Optics Infobase Conference Papers, December 1, 2012.
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Drake, Tyler K., Michael G. DeSoto, Jennifer J. Peters, Marcus H. Henderson, Bonnie Thiele, Tammy Sinclair Bishop, Amy P. Murtha, David F. Katz, and Adam Wax. “In vivo optical imaging of human vaginal gel thickness distributions with a probe-based, dual-modality instrument.” Journal of Biomedical Optics 17, no. 11 (November 2012): 116014. https://doi.org/10.1117/1.jbo.17.11.116014.Full Text
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Kim, Sanghoon, Matthew T. Rinehart, Hansang Park, Yizheng Zhu, and Adam Wax. “Phase-sensitive OCT imaging of multiple nanoparticle species using spectrally multiplexed single pulse photothermal excitation.” Biomedical Optics Express 3, no. 10 (October 2012): 2579–86. https://doi.org/10.1364/boe.3.002579.Full Text
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Li, You Leo, Kevin Seekell, Hsiangkuo Yuan, Francisco E. Robles, and Adam Wax. “Multispectral nanoparticle contrast agents for true-color spectroscopic optical coherence tomography.” Biomedical Optics Express 3, no. 8 (August 2012): 1914–23. https://doi.org/10.1364/boe.3.001914.Full Text
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Giacomelli, M. G., and A. Wax. “Imaging contrast and resolution in multiply scattered low coherence interferometry.” Ieee Journal on Selected Topics in Quantum Electronics 18, no. 3 (June 20, 2012): 1050–58. https://doi.org/10.1109/JSTQE.2011.2161272.Full Text
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Rinehart, Matthew, Yizheng Zhu, and Adam Wax. “Quantitative phase spectroscopy.” Biomedical Optics Express 3, no. 5 (May 2012): 958–65. https://doi.org/10.1364/boe.3.000958.Full Text
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Zhu, Yizheng, Neil G. Terry, and Adam Wax. “Angle-resolved low-coherence interferometry: an optical biopsy technique for clinical detection of dysplasia in Barrett's esophagus.” Expert Review of Gastroenterology & Hepatology 6, no. 1 (February 2012): 37–41. https://doi.org/10.1586/egh.11.83.Full Text
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Seekell, Kevin, Hillel Price, Stella Marinakos, and Adam Wax. “Optimization of immunolabeled plasmonic nanoparticles for cell surface receptor analysis.” Methods (San Diego, Calif.) 56, no. 2 (February 2012): 310–16. https://doi.org/10.1016/j.ymeth.2011.08.017.Full Text
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Kim, S., M. T. Rinehart, Y. Zhu, and A. Wax. “Spectrally multiplexed photothermal OCT and novel detection methods.” Cleo: Applications and Technology, Cleo at 2012, January 1, 2012. https://doi.org/10.1364/cleo_at.2012.jth3j.3.Full Text
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Li, Y., F. E. Robles, K. Seekell, and A. P. Wax. “Assessing nanoparticle concentration using METRiCS optical coherence tomography.” Biomedical Optics, Biomed 2012, January 1, 2012. https://doi.org/10.1364/biomed.2012.bw2a.7.Full Text
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Matthews, Thomas E., and Adam Wax. “High-efficiency diffuse Raman spectroscopy through a fiber bundle.” Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual International Conference 2012 (January 2012): 1181–83. https://doi.org/10.1109/embc.2012.6346147.Full Text
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Wax, A. “Coherence imaging for early cancer detection.” Cleo: Applications and Technology, Cleo at 2012, January 1, 2012. https://doi.org/10.1364/cleo_at.2012.ath1m.1.Full Text
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Wax, A., M. G. Giacomelli, T. E. Matthews, M. T. Rinehart, F. E. Robles, and Y. Zhu. “Optical spectroscopy of biological cells.” Advances in Optics and Photonics 4, no. 3 (January 1, 2012): 322–78. https://doi.org/10.1364/AOP.4.000322.Full Text
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Zhu, Y., M. R. Lyons, A. E. West, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast (SD-DIC) microscopy for measuring live cell dynamics.” Biomedical Optics, Biomed 2012, January 1, 2012. https://doi.org/10.1364/biomed.2012.bm4b.5.Full Text
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Satterwhite, L. L., N. T. Shaked, D. D. Cyr, M. J. Telen, G. A. Truskey, and A. Wax. “Novel optical signature for sickle cell trait red blood cells.” Frontiers in Optics, Fio 2012, January 1, 2012. https://doi.org/10.1364/fio.2012.fw6a.10.Full Text
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Rinehart, Matthew T., Tyler K. Drake, Francisco E. Robles, Lisa C. Rohan, David Katz, and Adam Wax. “Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy.” Journal of Biomedical Optics 16, no. 12 (December 2011): 120510. https://doi.org/10.1117/1.3665439.Full Text
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Robles, Francisco E., Lisa L. Satterwhite, and Adam Wax. “Nonlinear phase dispersion spectroscopy.” Optics Letters 36, no. 23 (December 2011): 4665–67. https://doi.org/10.1364/ol.36.004665.Full Text
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Shaked, N. T., M. T. Rinehart, and A. Wax. “Quantitative phase microscopy of biological cell dynamics by wide-field digital interferometry.” Springer Series in Surface Sciences 46, no. 1 (December 1, 2011): 169–98. https://doi.org/10.1007/978-3-642-15813-1_7.Full Text
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Robles, Francisco E., Christy Wilson, Gerald Grant, and Adam Wax. “Molecular imaging true-colour spectroscopic optical coherence tomography.” Nat Photonics 5, no. 12 (December 1, 2011): 744–47. https://doi.org/10.1038/nphoton.2011.257.Full Text Link to Item
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Crow, Matthew J., Kevin Seekell, Julie H. Ostrander, and Adam Wax. “Monitoring of receptor dimerization using plasmonic coupling of gold nanoparticles.” Acs Nano 5, no. 11 (November 2011): 8532–40. https://doi.org/10.1021/nn201451c.Full Text
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Seekell, Kevin, Matthew J. Crow, Stella Marinakos, Julie Ostrander, Ashutosh Chilkoti, and Adam Wax. “Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles.” Journal of Biomedical Optics 16, no. 11 (November 2011): 116003. https://doi.org/10.1117/1.3646529.Full Text
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Drake, Tyler K., Michael G. Desoto, Jennifer J. Peters, Marcus H. Henderson, Amy P. Murtha, David F. Katz, and Adam Wax. “Design and validation of a multiplexed low coherence interferometry instrument for in vivo clinical measurement of microbicide gel thickness distribution.” Biomedical Optics Express 2, no. 10 (October 2011): 2850–58. https://doi.org/10.1364/boe.2.002850.Full Text
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Terry, Neil, Yizheng Zhu, Julie K. M. Thacker, John Migaly, Cynthia Guy, Christopher R. Mantyh, and Adam Wax. “Detection of intestinal dysplasia using angle-resolved low coherence interferometry.” J Biomed Opt 16, no. 10 (October 2011): 106002. https://doi.org/10.1117/1.3631799.Full Text Link to Item
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Wax, Adam, Neil G. Terry, Evan S. Dellon, and Nicholas J. Shaheen. “Angle-resolved low coherence interferometry for detection of dysplasia in Barrett's esophagus.” Gastroenterology 141, no. 2 (August 2011): 443-447.e2. https://doi.org/10.1053/j.gastro.2011.06.020.Full Text
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Chalut, Kevin J., Karina Kulangara, Adam Wax, and Kam W. Leong. “Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture.” Integrative Biology : Quantitative Biosciences From Nano to Macro 3, no. 8 (August 2011): 863–67. https://doi.org/10.1039/c1ib00003a.Full Text
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Giacomelli, M., and A. Wax. “Coherent detection of diffusely scattered light for extending depth using multiply scattered low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7896 (May 12, 2011). https://doi.org/10.1117/12.874089.Full Text
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Rinehart, M. T., J. Lacroix, M. Henderson, D. Katz, and A. Wax. “Simultaneous confocal fluorescence microscopy and optical coherence tomography for drug distribution and tissue integrity assessment.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7890 (May 2, 2011). https://doi.org/10.1117/12.874986.Full Text
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Crow, M. J., K. Seekell, S. Marinakos, J. Ostrander, A. Chilkoti, and A. P. Wax. “Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7911 (April 29, 2011). https://doi.org/10.1117/12.874093.Full Text
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Shaked, N. T., L. L. Satterwhite, N. Bursac, and A. Wax. “Whole cell imaging based on wide-field interferometric phase microscopy and its application to cardiomyocytes.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7904 (April 29, 2011). https://doi.org/10.1117/12.874224.Full Text
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Giacomelli, M., Y. Zhu, J. Lee, and A. Wax. “Determining size, shape, and orientation of non-spherical scatterers using the fiber optic interferometric two-dimensional scattering (FITS) system.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7907 (March 31, 2011). https://doi.org/10.1117/12.874081.Full Text
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Robles, F. E., Y. Zhu, J. Lee, S. Sharma, and A. Wax. “Fourier domain low coherence interferometry for detection of early colorectal cancer development in the AOM rat model.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7907 (March 31, 2011). https://doi.org/10.1117/12.872929.Full Text
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Crow, Matthew J., Kevin Seekell, and Adam Wax. “Polarization mapping of nanoparticle plasmonic coupling.” Optics Letters 36, no. 5 (March 2011): 757–59. https://doi.org/10.1364/ol.36.000757.Full Text
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Shaked, Natan T., Lisa L. Satterwhite, Marilyn J. Telen, George A. Truskey, and Adam Wax. “Quantitative microscopy and nanoscopy of sickle red blood cells performed by wide field digital interferometry.” J Biomed Opt 16, no. 3 (March 2011): 030506. https://doi.org/10.1117/1.3556717.Full Text Link to Item
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Giacomelli, Michael G., and Adam Wax. “Imaging beyond the ballistic limit in coherence imaging using multiply scattered light.” Optics Express 19, no. 5 (February 2011): 4268–79. https://doi.org/10.1364/oe.19.004268.Full Text
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Zhu, Yizheng, Natan T. Shaked, Lisa L. Satterwhite, and Adam Wax. “Spectral-domain differential interference contrast microscopy.” Optics Letters 36, no. 4 (February 2011): 430–32. https://doi.org/10.1364/ol.36.000430.Full Text
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Drake, T., J. Peters, M. Henderson, M. DeSoto, D. Katz, and A. Wax. “Multimodal optical detection of intravaginal microbicide gel coating thickness distribution.” Optics Infobase Conference Papers, January 1, 2011.
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Drake, T., J. Peters, M. Henderson, M. DeSoto, D. Katz, and A. Wax. “Multimodal optical detection of intravaginal microbicide gel coating thickness distribution.” Optics Infobase Conference Papers, January 1, 2011. https://doi.org/10.1364/omp.2011.otub5.Full Text
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Drake, T., J. Peters, M. Henderson, M. DeSoto, D. Katz, and A. Wax. “Multimodal optical detection of intravaginal microbicide gel coating thickness distribution.” Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Whole-cell analysis of cardiomyocytes with combined quantitative phase and two-channel fluorescence microscopy.” Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Real-time quantitative phase and dual-channel fluorescence microscopy for studying cellular and biomolecular dynamics.” Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Whole-cell analysis of cardiomyocytes with combined quantitative phase and two-channel fluorescence microscopy.” Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Real-time quantitative phase and dual-channel fluorescence microscopy for studying cellular and biomolecular dynamics.” Optics Infobase Conference Papers, 2011.
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Robles, F. E., and A. Wax. “Spectroscopic optical coherence tomography for quantitative molecular imaging.” Optics Infobase Conference Papers, January 1, 2011.
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Robles, F. E., and A. Wax. “Spectroscopic optical coherence tomography for quantitative molecular imaging.” Optics Infobase Conference Papers, January 1, 2011. https://doi.org/10.1364/omp.2011.otub4.Full Text
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Robles, F. E., and A. Wax. “Spectroscopic optical coherence tomography for quantitative molecular imaging.” Optics Infobase Conference Papers, 2011.
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Shaked, N. T., and A. Wax. “Quantitative analysis of three-dimensional biological cells using interferometric microscopy.” Proceedings of Spie the International Society for Optical Engineering 8043 (January 1, 2011). https://doi.org/10.1117/12.882357.Full Text
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Skala, M. C., M. J. Crow, A. Wax, and J. A. Izatt. “Photothermal optical coherence tomography for molecular imaging.” Optics Infobase Conference Papers, 2011.
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Skala, M. C., M. J. Crow, A. Wax, and J. A. Izatt. “Photothermal optical coherence tomography for molecular imaging.” Optics Infobase Conference Papers, 2011.
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Terry, Neil G., Yizheng Zhu, Matthew T. Rinehart, William J. Brown, Steven C. Gebhart, Stephanie Bright, Elizabeth Carretta, et al. “Detection of dysplasia in Barrett's esophagus with in vivo depth-resolved nuclear morphology measurements.” Gastroenterology 140, no. 1 (January 2011): 42–50. https://doi.org/10.1053/j.gastro.2010.09.008.Full Text
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Wax, Adam, and Kevin J. Chalut. “Nuclear morphology measurements with angle-resolved low coherence interferometry for application to cell biology and early cancer detection.” Analytical Cellular Pathology (Amsterdam) 34, no. 5 (January 2011): 207–22. https://doi.org/10.3233/acp-2011-0017.Full Text
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Zhu, Y., N. T. Shaked, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast microscopy.” Optics Infobase Conference Papers, 2011.
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Zhu, Y., N. T. Shaked, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast microscopy.” Optics Infobase Conference Papers, 2011.
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Zhu, Yizheng, Neil G. Terry, John T. Woosley, Nicholas J. Shaheen, and Adam Wax. “Design and validation of an angle-resolved low-coherence interferometry fiber probe for in vivo clinical measurements of depth-resolved nuclear morphology.” Journal of Biomedical Optics 16, no. 1 (January 2011): 011003. https://doi.org/10.1117/1.3520130.Full Text
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Zhu, Yizheng, Neil G. Terry, and Adam Wax. “Development of angle-resolved low coherence interferometry for clinical detection of dysplasia.” Journal of Carcinogenesis 10 (January 2011): 19. https://doi.org/10.4103/1477-3163.83935.Full Text
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Crow, Matthew J., Stella M. Marinakos, J Michael Cook, Ashutosh Chilkoti, and Adam Wax. “Plasmonic flow cytometry by immunolabeled nanorods.” Cytometry A 79, no. 1 (January 2011): 57–65. https://doi.org/10.1002/cyto.a.20994.Full Text Link to Item
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Shaked, N. T., and A. Wax. “New directions in interferometric phase microscopy of biological cell dynamics.” Optics Infobase Conference Papers, December 1, 2010.
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Wax, A. “Coherence imaging.” Optics Infobase Conference Papers, December 1, 2010.
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Robles, Francisco E., and Adam Wax. “Separating the scattering and absorption coefficients using the real and imaginary parts of the refractive index with low-coherence interferometry.” Optics Letters 35, no. 17 (September 2010): 2843–45. https://doi.org/10.1364/ol.35.002843.Full Text Open Access Copy
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Rinehart, Matthew T., Natan T. Shaked, Nathan J. Jenness, Robert L. Clark, and Adam Wax. “Simultaneous two-wavelength transmission quantitative phase microscopy with a color camera.” Optics Letters 35, no. 15 (August 2010): 2612–14. https://doi.org/10.1364/ol.35.002612.Full Text Open Access Copy
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Robles, Francisco E., Yizheng Zhu, Jin Lee, Sheela Sharma, and Adam Wax. “Detection of early colorectal cancer development in the azoxymethane rat carcinogenesis model with Fourier domain low coherence interferometry.” Biomedical Optics Express 1, no. 2 (August 2010): 736–45. https://doi.org/10.1364/boe.1.000736.Full Text
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Shaked, Natan T., Lisa L. Satterwhite, Nenad Bursac, and Adam Wax. “Whole-cell-analysis of live cardiomyocytes using wide-field interferometric phase microscopy.” Biomedical Optics Express 1, no. 2 (August 2010): 706–19. https://doi.org/10.1364/boe.1.000706.Full Text Open Access Copy
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Giacomelli, M., Y. Zhu, J. Lee, and A. Wax. “Size and shape determination of spheroidal scatterers using two-dimensional angle resolved scattering.” Optics Express 18, no. 14 (July 5, 2010): 14616–26.
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Giacomelli, M. G., K. J. Chalut, J. H. Ostrander, and A. Wax. “Review of the application of T-matrix calculations for determining the structure of cell nuclei with angle-resolved light scattering measurements.” Ieee Journal on Selected Topics in Quantum Electronics 16, no. 4 (July 1, 2010): 900–908. https://doi.org/10.1109/JSTQE.2009.2031984.Full Text
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Giacomelli, Michael, Yizheng Zhu, John Lee, and Adam Wax. “Size and shape determination of spheroidal scatterers using two-dimensional angle resolved scattering.” Optics Express 18, no. 14 (July 2010): 14616–26. https://doi.org/10.1364/oe.18.014616.Full Text Open Access Copy
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Ehlers, M. D., Thomas Mark Newpher, N. T. Shaked, and A. Wax. “Parallel on-axis holographic phase microscopy of biological cells and unicellular microorganism dynamics.,” May 20, 2010.Open Access Copy
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Robles, F. E., and A. Wax. “Measuring structural features using a dual window method for light scattering spectroscopy and Fourier-domain low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7573 (May 7, 2010). https://doi.org/10.1117/12.842375.Full Text
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Terry, N. G., Y. Zhu, and A. Wax. “Fourier-domain angle-resolved low coherence interferometry for clinical detection of dysplasia.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7573 (May 7, 2010). https://doi.org/10.1117/12.842464.Full Text
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Shaked, Natan T., Yizheng Zhu, Nima Badie, Nenad Bursac, and Adam Wax. “Reflective interferometric chamber for quantitative phase imaging of biological sample dynamics.” Journal of Biomedical Optics 15, no. 3 (May 2010): 030503. https://doi.org/10.1117/1.3420179.Full Text
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Zhu, Yizheng, Michael G. Giacomelli, and Adam Wax. “Fiber-optic interferometric two-dimensional scattering-measurement system.” Optics Letters 35, no. 10 (May 2010): 1641–43. https://doi.org/10.1364/ol.35.001641.Full Text Open Access Copy
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Shaked, Natan T., Thomas M. Newpher, Michael D. Ehlers, and Adam Wax. “Parallel on-axis holographic phase microscopy of biological cells and unicellular microorganism dynamics.” Applied Optics 49, no. 15 (May 2010): 2872–78. https://doi.org/10.1364/ao.49.002872.Full Text Open Access Copy
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Chalut, Kevin J., Karina Kulangara, Michael G. Giacomelli, Adam Wax, and Kam W. Leong. “Deformation of stem cell nuclei by nanotopographical cues.” Soft Matter 6, no. 8 (April 2010): 1675–81. https://doi.org/10.1039/b921206j.Full Text Open Access Copy
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Robles, Francisco E., and Adam Wax. “Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.” Optics Letters 35, no. 3 (February 2010): 360–62. https://doi.org/10.1364/ol.35.000360.Full Text Open Access Copy
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Giacomelli, M., Y. Zhu, J. Lee, and A. Wax. “Size and shape determination of spheroidal scatterers using two-dimensional angle resolved scattering.” Optics Express 18, no. 14 (2010): 14568–76.
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Robles, Francisco E., Shwetadwip Chowdhury, and Adam Wax. “Assessing hemoglobin concentration using spectroscopic optical coherence tomography for feasibility of tissue diagnostics.” Biomedical Optics Express 1 (2010): 310–17.
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Shaked, N. T., and A. Wax. “Quantitative phase microscopy of live biological cell dynamics.” Aip Conference Proceedings 1236 (January 1, 2010): 283–88. https://doi.org/10.1063/1.3426127.Full Text
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Shaked, Natan T., John D. Finan, Farshid Guilak, and Adam Wax. “Quantitative phase microscopy of articular chondrocyte dynamics by wide-field digital interferometry.” Journal of Biomedical Optics 15, no. 1 (January 2010): 010505. https://doi.org/10.1117/1.3290242.Full Text
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Chowdhury, Shwetadwip, Francisco E. Robles, and Adam Wax. “Detecting Hemoglobin Concentration Using the Dual Window Method for Processing Spectroscopic Optical Coherence Tomography Signals.” Digital Holography and Three Dimensional Imaging, 2010, JMA43–JMA43.
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Finan, J. D., K. J. Chalut, A. Wax, and F. Guilak. “Nonlinear osmotic properties of the cell nucleus.” Proceedings of the Asme Summer Bioengineering Conference 2009, Sbc2009, no. PART A (December 1, 2009): 93–94. https://doi.org/10.1115/SBC2009-206197.Full Text
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Rinehart, M. T., N. T. Shaked, and A. Wax. “Two-wavelength quantitative phase unwrapping of dynamic biological processes.” Optics Infobase Conference Papers, December 1, 2009.
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Shaked, N. T., M. T. Rinehart, and A. Wax. “Dynamic quantitative phase microscopy of biological cells.” Optics Infobase Conference Papers, December 1, 2009.
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Wax, A., and K. Sokolov. “Molecular imaging and darkfield microspectroscopy of live cells using gold plasmonic nanoparticles.” Laser and Photonics Reviews 3, no. 1–2 (November 23, 2009): 146–58. https://doi.org/10.1002/lpor.200810011.Full Text
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Rinehart, M. T., N. T. Shaked, and A. Wax. “Two-wavelength quantitative phase unwrapping of dynamic biological processes.” 2009 Conference on Lasers and Electro Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, Cleo/Qels 2009, November 18, 2009.
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Shaked, N. T., M. T. Rinehart, and A. Wax. “Dynamic quantitative phase microscopy of biological cells.” 2009 Conference on Lasers and Electro Optics and 2009 Conference on Quantum Electronics and Laser Science Conference, Cleo/Qels 2009, November 16, 2009.
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Graf, Robert N., Francisco E. Robles, Xiaoxin Chen, and Adam Wax. “Detecting precancerous lesions in the hamster cheek pouch using spectroscopic white-light optical coherence tomography to assess nuclear morphology via spectral oscillations.” Journal of Biomedical Optics 14, no. 6 (November 2009): 064030. https://doi.org/10.1117/1.3269680.Full Text
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Zhu, Yizheng, Neil G. Terry, and Adam Wax. “Scanning fiber angle-resolved low coherence interferometry.” Optics Letters 34, no. 20 (October 2009): 3196–98. https://doi.org/10.1364/ol.34.003196.Full Text
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Shaked, Natan T., Yizheng Zhu, Matthew T. Rinehart, and Adam Wax. “Two-step-only phase-shifting interferometry with optimized detector bandwidth for microscopy of live cells.” Optics Express 17, no. 18 (August 2009): 15585–91. https://doi.org/10.1364/oe.17.015585.Full Text
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Crow, M., S. Marinakos, A. Chilkoti, and A. Wax. “Simultaneous molecular imaging of EGFR and HER2 using hyperspectral darkfield microscopy and immunotargeted nanoparticles.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7192 (June 12, 2009). https://doi.org/10.1117/12.808968.Full Text
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Giacomelli, M., K. Chalut, J. Ostrander, and A. Wax. “T-matrix based inverse light scattering analysis using angle resolved low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7187 (June 12, 2009). https://doi.org/10.1117/12.808059.Full Text
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Graf, R. N., F. Robles, X. Chen, and A. Wax. “Detecting neoplastic development in the hamster cheek pouch using Fourier Domain Low Coherence Interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7187 (June 12, 2009). https://doi.org/10.1117/12.809494.Full Text
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Terry, N. G., Y. Zhu, M. Rinehart, and A. Wax. “Optimizing Fourier-domain angle resolved low coherence interferometry for clinical use.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7187 (June 12, 2009). https://doi.org/10.1117/12.808021.Full Text
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Drake, T. K., F. Robles, M. DeSoto, M. H. Henderson, D. F. Katz, and A. Wax. “Development of an integrated endoscopic device for multiplexed low coherence interferometry (LCI) measurements of microbicide gel thickness.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7169 (June 8, 2009). https://doi.org/10.1117/12.809114.Full Text
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Robles, F. E., R. N. Graf, and A. Wax. “Dual window method for processing spectroscopic optical coherence tomography signals with high spectral and spatial resolution.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7168 (May 5, 2009). https://doi.org/10.1117/12.809465.Full Text
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Amoozegar, Cyrus, Michael G. Giacomelli, Justin D. Keener, Kevin J. Chalut, and Adam Wax. “Experimental verification of T-matrix-based inverse light scattering analysis for assessing structure of spheroids as models of cell nuclei.” Applied Optics 48, no. 10 (April 2009): D20–25. https://doi.org/10.1364/ao.48.000d20.Full Text
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Drake, Tyler K., Francisco E. Robles, and Adam Wax. “Multiplexed low coherence interferometry instrument for measuring microbicide gel thickness distribution.” Applied Optics 48, no. 10 (April 2009): D14–19. https://doi.org/10.1364/ao.48.000d14.Full Text
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Nusz, Greg J., Adam C. Curry, Stella M. Marinakos, Adam Wax, and Ashutosh Chilkoti. “Rational selection of gold nanorod geometry for label-free plasmonic biosensors.” Acs Nano 3, no. 4 (April 2009): 795–806. https://doi.org/10.1021/nn8006465.Full Text
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Robles, Francisco, Robert N. Graf, and Adam Wax. “Dual window method for processing spectroscopic optical coherence tomography signals with simultaneously high spectral and temporal resolution.” Optics Express 17, no. 8 (April 2009): 6799–6812. https://doi.org/10.1364/oe.17.006799.Full Text
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Wallace, Michael B., Adam Wax, David N. Roberts, and Robert N. Graf. “Reflectance spectroscopy.” Gastrointestinal Endoscopy Clinics of North America 19, no. 2 (April 2009): 233–42. https://doi.org/10.1016/j.giec.2009.02.008.Full Text
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Crow, Matthew J., Gerald Grant, James M. Provenzale, and Adam Wax. “Molecular imaging and quantitative measurement of epidermal growth factor receptor expression in live cancer cells using immunolabeled gold nanoparticles.” Ajr Am J Roentgenol 192, no. 4 (April 2009): 1021–28. https://doi.org/10.2214/AJR.07.3535.Full Text Link to Item
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Finan, John D., Kevin J. Chalut, Adam Wax, and Farshid Guilak. “Nonlinear osmotic properties of the cell nucleus.” Annals of Biomedical Engineering 37, no. 3 (March 2009): 477–91. https://doi.org/10.1007/s10439-008-9618-5.Full Text
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Shaked, Natan T., Matthew T. Rinehart, and Adam Wax. “Dual-interference-channel quantitative-phase microscopy of live cell dynamics.” Optics Letters 34, no. 6 (March 2009): 767–69. https://doi.org/10.1364/ol.34.000767.Full Text
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Chalut, Kevin J., Julie Hanson Ostrander, Michael G. Giacomelli, and Adam Wax. “Light scattering measurements of subcellular structure provide noninvasive early detection of chemotherapy-induced apoptosis.” Cancer Research 69, no. 3 (February 2009): 1199–1204. https://doi.org/10.1158/0008-5472.can-08-3079.Full Text
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Kim, K. H., T. K. Drake, M. G. DeSoto, M. H. Henderson, D. F. Katz, and A. Wax. “Development of an integrated multiplexed low coherence interferometer and fluorescence clinical endoscope.” Optics Infobase Conference Papers, January 1, 2009.
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Giacomelli, Michael G., Kevin J. Chalut, Julie H. Ostrander, and Adam Wax. “Application of the T-matrix method to determine the structure of spheroidal cell nuclei with angle-resolved light scattering.” Optics Letters 33, no. 21 (November 2008): 2452–54. https://doi.org/10.1364/ol.33.002452.Full Text
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Skala, Melissa C., Matthew J. Crow, Adam Wax, and Joseph A. Izatt. “Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres.” Nano Letters 8, no. 10 (October 2008): 3461–67. https://doi.org/10.1021/nl802351p.Full Text
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Chalut, Kevin J., Michael G. Giacomelli, and Adam Wax. “Application of Mie theory to assess structure of spheroidal scattering in backscattering geometries.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 25, no. 8 (August 2008): 1866–74. https://doi.org/10.1364/josaa.25.001866.Full Text
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Chalut, Kevin J., Sulin Chen, John D. Finan, Michael G. Giacomelli, Farshid Guilak, Kam W. Leong, and Adam Wax. “Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry.” Biophysical Journal 94, no. 12 (June 2008): 4948–56. https://doi.org/10.1529/biophysj.107.124107.Full Text
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Graf, R. N., W. J. Brown, and A. Wax. “Parallel frequency-domain optical coherence tomography scatter-mode imaging of the hamster cheek pouch using a thermal light source.” Optics Letters 33, no. 12 (June 2008): 1285–87. https://doi.org/10.1364/ol.33.001285.Full Text
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Chalut, K. J., J. H. Ostrander, and A. Wax. “Detection of structural and functional changes in biological materials using angle-resolved low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6864 (April 21, 2008). https://doi.org/10.1117/12.764213.Full Text
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Graf, R. N., X. Chen, W. Brown, and A. Wax. “Measuring neoplastic transformation in the hamster cheek pouch using Fourier domain low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6864 (April 21, 2008). https://doi.org/10.1117/12.764045.Full Text
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Terry, N. G., Y. Zhu, W. J. Brown, and A. Wax. “Development of a clinical Fourier-domain angle resolved low coherence interferometry system for in vivo measurements.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6864 (April 21, 2008). https://doi.org/10.1117/12.763782.Full Text
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Nusz, Greg J., Stella M. Marinakos, Adam C. Curry, Andreas Dahlin, Fredrik Höök, Adam Wax, and Ashutosh Chilkoti. “Label-free plasmonic detection of biomolecular binding by a single gold nanorod.” Analytical Chemistry 80, no. 4 (February 2008): 984–89. https://doi.org/10.1021/ac7017348.Full Text
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Amoozegar, C., M. G. Giacomelli, K. J. Chalut, and A. Wax. “Modeling advances for measuring spheroidal geometries using angle-resolved low coherence interferometry.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.btuf7.Full Text
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Brown, W. J., J. W. Pyhtila, N. G. Terry, K. J. Chalut, T. A. D’Amico, T. A. Sporn, J. V. Obando, and A. Wax. “Review and recent development of angle-resolved low-coherence interferometry for detection of precancerous cells in human esophageal epithelium.” Ieee Journal on Selected Topics in Quantum Electronics 14, no. 1 (January 1, 2008): 88–96. https://doi.org/10.1109/JSTQE.2007.913969.Full Text
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Crow, M., and A. Wax. “Development of a novel hyperspectral darkfield microscopy system for characterization of nanoparticle sensors.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.bsue6.Full Text
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Curry, Adam C., Matthew Crow, and Adam Wax. “Molecular imaging of epidermal growth factor receptor in live cells with refractive index sensitivity using dark-field microspectroscopy and immunotargeted nanoparticles.” Journal of Biomedical Optics 13, no. 1 (January 2008): 014022. https://doi.org/10.1117/1.2837450.Full Text
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Drake, T., F. Robles, and A. Wax. “Multiplexed low-coherence interferometry instrument for measuring microbicide gel thickness distribution.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.bmd81.Full Text
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Giacomelli, M., K. Chalut, and A. Wax. “A comparison of mie theory and the t-matrix method for estimating the size of cell nuclei.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.btuf6.Full Text
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Rinehart, M., M. Giacomelli, K. Chalut, and A. Wax. “Quantitative phase microscopy with multi-wavelength unwrapping and tomographic 3D reconstruction.” Optics Infobase Conference Papers, January 1, 2008.
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Rinehart, M., M. Giacomelli, K. Chalut, and A. Wax. “Quantitative phase microscopy with multi-wavelength unwrapping and tomographic 3D reconstruction.” Optics Infobase Conference Papers, January 1, 2008.
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Wax, A. “Analyzing light scattering from aspherical nuclei for cell biology and clinical applications.” Optics Infobase Conference Papers, January 1, 2008.
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Wax, A. “Darkfield microspectroscopy: From single nanoparticle biosensing to live cell molecular imaging.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.bsua2.Full Text
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Wax, Adam, and John W. Pyhtila. “In situ nuclear morphology measurements using light scattering as biomarkers of neoplastic change in animal models of carcinogenesis.” Disease Markers 25, no. 6 (January 2008): 291–301. https://doi.org/10.1155/2008/584101.Full Text
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Zhu, Y., N. G. Terry, W. J. Brown, and A. Wax. “Design and verification of an endoscopic pre-cancer detection system based on angle-resolved low coherence interferometry (a/LCI).” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.btuc8.Full Text
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Chalut, K., W. Brown, N. Terry, and A. Wax. “Quantitative phase microscopy with asynchronous digital holography system.” Conference on Lasers and Electro Optics, 2007, Cleo 2007, December 1, 2007. https://doi.org/10.1109/CLEO.2007.4453094.Full Text
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Crow, M., A. Curry, and A. Wax. “Molecular imaging of EGFR expression in live cancer cells using immunotargeted nanoparticles.” Conference on Lasers and Electro Optics, 2007, Cleo 2007, December 1, 2007. https://doi.org/10.1109/CLEO.2007.4452483.Full Text
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Graf, R. N., and A. Wax. “Development of a pre-clinical Fourier domain low coherence interferometry system.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6446 (August 31, 2007). https://doi.org/10.1117/12.699373.Full Text
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Pyhtila, J. W., and A. Wax. “Development of a portable frequency-domain angle-resolved low coherence interferometry system.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6446 (August 31, 2007). https://doi.org/10.1117/12.699143.Full Text
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Wax, A., and V. Backman. “Progress in Biomedical Optics and Imaging - Proceedings of SPIE: Introduction.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6446 (August 31, 2007).
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Graf, Robert N., and Adam Wax. “Temporal coherence and time-frequency distributions in spectroscopic optical coherence tomography.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 24, no. 8 (August 2007): 2186–95. https://doi.org/10.1364/josaa.24.002186.Full Text
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Keener, Justin D., Kevin J. Chalut, John W. Pyhtila, and Adam Wax. “Application of Mie theory to determine the structure of spheroidal scatterers in biological materials.” Optics Letters 32, no. 10 (May 2007): 1326–28. https://doi.org/10.1364/ol.32.001326.Full Text
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Curry, Adam, Gregory Nusz, Ashutosh Chilkoti, and Adam Wax. “Analysis of total uncertainty in spectral peak measurements for plasmonic nanoparticle-based biosensors.” Applied Optics 46, no. 10 (April 2007): 1931–39. https://doi.org/10.1364/ao.46.001931.Full Text
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Pyhtila, John W., and Adam Wax. “Polarization effects on scatterer sizing accuracy analyzed with frequency-domain angle-resolved low-coherence interferometry.” Applied Optics 46, no. 10 (April 2007): 1735–41. https://doi.org/10.1364/ao.46.001735.Full Text
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Chalut, Kevin J., William J. Brown, and Adam Wax. “Quantitative phase microscopy with asynchronous digital holography.” Optics Express 15, no. 6 (March 2007): 3047–52. https://doi.org/10.1364/oe.15.003047.Full Text
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Pyhtila, John W., Kevin J. Chalut, Jeffrey D. Boyer, Justin Keener, Thomas D’Amico, Marcia Gottfried, Frank Gress, and Adam Wax. “In situ detection of nuclear atypia in Barrett's esophagus by using angle-resolved low-coherence interferometry.” Gastrointest Endosc 65, no. 3 (March 2007): 487–91. https://doi.org/10.1016/j.gie.2006.10.016.Full Text Link to Item
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Chalut, Kevin J., Laura A. Kresty, John W. Pyhtila, Ronald Nines, Maureen Baird, Vernon E. Steele, and Adam Wax. “In situ assessment of intraepithelial neoplasia in hamster trachea epithelium using angle-resolved low-coherence interferometry.” Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology 16, no. 2 (February 2007): 223–27. https://doi.org/10.1158/1055-9965.epi-06-0418.Full Text
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Chalut, K., W. Brown, N. Terry, and A. Wax. “Quantitative phase microscopy with asynchronous digital holography system.” Optics Infobase Conference Papers, 2007.
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Crow, M., A. Curry, and A. Wax. “Molecular imaging of EGFR expression in live cancer cells using immunotargeted nanoparticles.” Optics Infobase Conference Papers, 2007.
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Kelloff, Gary J., Daniel C. Sullivan, Houston Baker, Lawrence P. Clarke, Robert Nordstrom, James L. Tatum, Gary S. Dorfman, et al. “Workshop on imaging science development for cancer prevention and preemption.” Cancer Biomark 3, no. 1 (2007): 1–33. https://doi.org/10.3233/cbm-2007-3101.Full Text Link to Item
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Wax, A., and M. Crow. “Molecular imaging and microspectroscopy of live cells using immunotargeted nanoparticles.” Optics Infobase Conference Papers, January 1, 2007.
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Hunter, Martin, Vadim Backman, Gabriel Popescu, Maxim Kalashnikov, Charles W. Boone, Adam Wax, Venkatesh Gopal, Kamran Badizadegan, Gary D. Stoner, and Michael S. Feld. “Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection.” Physical Review Letters 97, no. 13 (September 2006): 138102. https://doi.org/10.1103/physrevlett.97.138102.Full Text
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Curry, Adam, William L. Hwang, and Adam Wax. “Epi-illumination through the microscope objective applied to darkfield imaging and microspectroscopy of nanoparticle interaction with cells in culture.” Optics Express 14, no. 14 (July 2006): 6535–42. https://doi.org/10.1364/oe.14.006535.Full Text
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Pyhtila, John W., Hongwei Ma, Andrew J. Simnick, Ashutosh Chilkoti, and Adam Wax. “Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry.” Journal of Biomedical Optics 11, no. 3 (May 2006): 34022. https://doi.org/10.1117/1.2209561.Full Text
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Braun, Kelly E., Jeffrey D. Boyer, Marcus H. Henderson, David F. Katz, and Adam Wax. “Label-free measurement of microbicidal gel thickness using low-coherence interferometry.” Journal of Biomedical Optics 11, no. 2 (March 2006): 020504. https://doi.org/10.1117/1.2192767.Full Text
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Pyhtila, John W., Jeffrey D. Boyer, Kevin J. Chalut, and Adam Wax. “Fourier-domain angle-resolved low coherence interferometry through an endoscopic fiber bundle for light-scattering spectroscopy.” Optics Letters 31, no. 6 (March 2006): 772–74. https://doi.org/10.1364/ol.31.000772.Full Text
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Boyer, J. D., J. W. Pyhtila, and A. Wax. “Multi-layer scattering tissue phantom for assessing angle-resolved low coherence interferometryprecancer diagnostic technique.” Optics Infobase Conference Papers, January 1, 2006.
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Braun, K. E., J. W. Pyhtila, and A. Wax. “Quantitative characterization of spectrograph entrance slit width on roll-off of fourier domain optical coherence tomography signals.” Optics Infobase Conference Papers, January 1, 2006.
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Braun, K. E., and A. Wax. “Improved simulations for measuring microbicidal gel thickness using low-coherence interferometry.” Optics Infobase Conference Papers, January 1, 2006.
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Chou, D. R., and A. P. Wax. “Optical scattering of confocal laser scanning reflectance microscopy in turbid media.” Optics Infobase Conference Papers, January 1, 2006.
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Curry, A. C., and A. Wax. “Sensitivity analysis of detecting plasmon resonance spectral shifts for nanoparticle based biosensors.” Optics Infobase Conference Papers, January 1, 2006.
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Curry, A., G. Nusz, A. Chilkoti, and A. Wax. “Measurement system for the high-throughput characterization of metal nanoparticles for biosensors.” Optics Infobase Conference Papers, January 1, 2006.
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Curry, A., and A. Wax. “Epi-illumination darkfield through a microscope objective for imaging and spectral analysis of nanoparticle interaction with cells in culture.” Optics Infobase Conference Papers, January 1, 2006.
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Pyhtila, J. W., J. D. Boyer, K. J. Chalut, and A. Wax. “Endoscopic fourier-domain angle-resolved low coherence interferometry for assessing nuclear morphology in human epithelial tissues.” Optics Infobase Conference Papers, January 1, 2006.
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“Improved design of a heterodyne angle-resolved low coherence interferometry system used for new chemoprevention and carcinogenesis studies.” Optics Infobase Conference Papers, January 1, 2006.
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Chov, D. R., and A. P. Wax. “Optical scattering of confocal laser scanning reflectance microscopy in turbid media.” 2005 Conference on Lasers and Electro Optics, Cleo 3 (December 1, 2005): 1578–80.
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Wax, Adam, John W. Pyhtila, Robert N. Graf, Ronald Nines, Charles W. Boone, Ramachandra R. Dasari, Michael S. Feld, Vernon E. Steele, and Gary D. Stoner. “Prospective grading of neoplastic change in rat esophagus epithelium using angle-resolved low-coherence interferometry.” Journal of Biomedical Optics 10, no. 5 (September 2005): 051604. https://doi.org/10.1117/1.2102767.Full Text
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Graf, R. N., and A. Wax. “Nuclear morphology measurements using Fourier domain low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5690 (July 21, 2005): 460–67. https://doi.org/10.1117/12.592227.Full Text
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Pyhtila, J. W., and A. Wax. “Rapid angle-resolved low coherence interferometry measurements.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5690 (July 21, 2005): 468–74. https://doi.org/10.1117/12.592012.Full Text
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Pyhtila, J. W., and A. Wax. “Coherent light scattering by in vitro cell arrays observed with angle-resolved low coherence interferometry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5690 (July 21, 2005): 334–41. https://doi.org/10.1117/12.592230.Full Text
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Vo-Dinh, T., W. S. Grundfest, D. A. Benaron, and G. E. Cohn. “Progress in Biomedical Optics and Imaging - Proceedings of SPIE: Introduction.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5692 (July 21, 2005).
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Graf, Robert N., and Adam Wax. “Nuclear morphology measurements using Fourier domain low coherence interferometry.” Optics Express 13, no. 12 (June 2005): 4693–98. https://doi.org/10.1364/opex.13.004693.Full Text
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Chou, Derrick R., Bradley A. Bower, and Adam Wax. “Low-cost, scalable laser scanning module for real-time reflectance and fluorescence confocal microscopy.” Applied Optics 44, no. 11 (April 2005): 2013–18. https://doi.org/10.1364/ao.44.002013.Full Text
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Curry, A., G. Nusz, A. Chilkoti, and Adam Wax. “Substrate effect on refractive index dependence of plasmon resonance for individual silver nanoparticles observed using darkfield microspectroscopy.” Optics Express 13, no. 7 (April 2005): 2668–77. https://doi.org/10.1364/opex.13.002668.Full Text
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Pyhtila, John W., and Adam Wax. “Improved interferometric detection of scattered light with a 4f imaging system.” Applied Optics 44, no. 10 (April 2005): 1785–91. https://doi.org/10.1364/ao.44.001785.Full Text
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Ahn, Andrew, Changhuei Yang, Adam Wax, Gabriel Popescu, Christopher Fang-Yen, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld. “Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer.” Applied Optics 44, no. 7 (March 2005): 1188–90. https://doi.org/10.1364/ao.44.001188.Full Text
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Wax, Adam. “Low-coherence light-scattering calculations for polydisperse size distributions.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 22, no. 2 (February 2005): 256–61. https://doi.org/10.1364/josaa.22.000256.Full Text
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Chou, D. R., and A. P. Wax. “Optical scattering of confocal laser scanning reflectance microscopy in turbid media.” Optics Infobase Conference Papers, January 1, 2005.
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Curry, A., G. Nusz, A. Chilkoti, and A. Wax. “Measurement system for the high-throughput characterization of metal nanoparticles for biosensors.” Optics Infobase Conference Papers, January 1, 2005.
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Curry, A., G. Nusz, A. Chilkoti, and A. Wax. “Measurement system for the high-throughput characterization of metal nanoparticles for biosensors.” 2005 Conference on Lasers and Electro Optics, Cleo 3 (January 1, 2005): 2160–62. https://doi.org/10.1109/cleo.2005.202402.Full Text
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Pyhtila, John W., and Adam Wax. “Rapid, depth-resolved light scattering measurements using Fourier domain, angle-resolved low coherence interferometry.” Optics Express 12, no. 25 (December 2004): 6178–83. https://doi.org/10.1364/opex.12.006178.Full Text
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Iwai, Hidenao, Christopher Fang-Yen, Gabriel Popescu, Adam Wax, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld. “Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry.” Optics Letters 29, no. 20 (October 2004): 2399–2401. https://doi.org/10.1364/ol.29.002399.Full Text
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Pyhtila, John, Robert Graf, and Adam Wax. “Determining nuclear morphology using an improved angle-resolved low coherence interferometry system.” Optics Express 11, no. 25 (December 2003): 3473–84. https://doi.org/10.1364/oe.11.003473.Full Text
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Tunnell, J. W., A. E. Desjardins, L. Galindo, I. Georgakoudi, S. A. McGee, J. Mirkovic, M. G. Mueller, et al. “Instrumentation for multi-modal spectroscopic diagnosis of epithelial dysplasia.” Technology in Cancer Research & Treatment 2, no. 6 (December 2003): 505–14. https://doi.org/10.1177/153303460300200603.Full Text
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Wax, Adam, Changhuei Yang, Markus G. Müller, Ronald Nines, Charles W. Boone, Vernon E. Steele, Gary D. Stoner, Ramachandra R. Dasari, and Michael S. Feld. “In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry.” Cancer Research 63, no. 13 (July 2003): 3556–59.
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Wax, Adam, Changhuei Yang, and Joseph A. Izatt. “Fourier-domain low-coherence interferometry for light-scattering spectroscopy.” Optics Letters 28, no. 14 (July 2003): 1230–32. https://doi.org/10.1364/ol.28.001230.Full Text
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Müller, M. G., A. Wax, I. Georgakoudi, R. R. Dasari, and M. S. Feld. “A reflectance spectrofluorimeter for real-time spectral diagnosis of disease.” Review of Scientific Instruments 73, no. 11 (November 1, 2002): 3933. https://doi.org/10.1063/1.1511795.Full Text
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Wax, Adam, Changhuei Yang, Vadim Backman, Kamran Badizadegan, Charles W. Boone, Ramachandra R. Dasari, and Michael S. Feld. “Cellular organization and substructure measured using angle-resolved low-coherence interferometry.” Biophysical Journal 82, no. 4 (April 2002): 2256–64. https://doi.org/10.1016/s0006-3495(02)75571-9.Full Text
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Wax, Adam, Changhuei Yang, Vadim Backman, Maxim Kalashnikov, Ramachandra R. Dasari, and Michael S. Feld. “Determination of particle size by using the angular distribution of backscattered light as measured with low-coherence interferometry.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 19, no. 4 (April 2002): 737–44. https://doi.org/10.1364/josaa.19.000737.Full Text
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Yang, C., A. Wax, R. R. Dasari, and M. S. Feld. “2π ambiguity-free optical distance measurement with subnanometer precision with a novel phase-crossing low-coherence interferometer.” Optics Letters 27, no. 2 (January 15, 2002): 77–79. https://doi.org/10.1364/OL.27.000077.Full Text
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Backman, V., R. Gurjar, L. T. Perelman, V. Gopal, M. Kalashnikov, K. Badizadegan, A. Wax, et al. “Imaging and measurement of cell structure and organization with submicron accuracy using light scattering spectroscopy.” Proceedings of Spie the International Society for Optical Engineering 4613 (January 1, 2002): 101–10. https://doi.org/10.1117/12.465234.Full Text
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Yang, C., A. Wax, K. Badizadegan, R. R. Dasari, and M. S. Feld. “The study of cell dynamics with a novel phase referenced low coherence interferometer with sub-wavelength and sub-hertz sensitivity.” Proceedings of Spie the International Society for Optical Engineering 4619 (January 1, 2002): 202–9. https://doi.org/10.1117/12.470484.Full Text
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Yang, Changhuei, A. Wax, R. R. Dasari, and M. S. Feld. “2π ambiguity-free optical distance measurement with subnanometer precision with a novel phase-crossing low-coherence interferometer.” Opt. Lett. (Usa) 27, no. 2 (2002): 77–79.
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Backman, V., V. Gopal, M. Kalashnikov, K. Badizadegan, R. Gurjar, A. Wax, I. Georgakoudi, et al. “Measuring cellular structure at submicrometer scale with light scattering spectroscopy.” Ieee Journal on Selected Topics in Quantum Electronics 7, no. 6 (November 1, 2001): 887–93. https://doi.org/10.1109/2944.983289.Full Text
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Yang, C., A. Wax, R. R. Dasari, and M. S. Feld. “Phase dispersion optical tomography applied to study sub-cellular motions.” Conference on Lasers and Electro Optics Europe Technical Digest, October 8, 2001, 326–27.
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Wax, A., C. Yang, R. R. Dasari, and M. S. Feld. “Path-length-resolved dynamic light scattering: Modeling the transition from single to diffusive scattering.” Applied Optics 40, no. 24 (August 20, 2001): 4222–27. https://doi.org/10.1364/AO.40.004222.Full Text
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Yang, C., A. Wax, M. S. Hahn, K. Badizadegan, R. R. Dasari, and M. S. Feld. “Phase-referenced interferometer with subwavelength and subhertz sensitivity applied to the study of cell membrane dynamics.” Optics Letters 26, no. 16 (August 15, 2001): 1271–73. https://doi.org/10.1364/OL.26.001271.Full Text
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Yang, C., A. Wax, R. R. Dasari, and M. S. Feld. “Phase-dispersion optical tomography.” Optics Letters 26, no. 10 (May 15, 2001): 686–88. https://doi.org/10.1364/OL.26.000686.Full Text
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Wax, A., C. Yang, R. R. Dasari, and M. S. Feld. “Measurement of angular distributions by use of low-coherence interferometry for light-scattering spectroscopy.” Optics Letters 26, no. 6 (March 15, 2001): 322–24. https://doi.org/10.1364/OL.26.000322.Full Text
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Yang, C., A. Wax, and M. S. Feld. “Measurement of the anomalous phase velocity of ballistic light in a random medium by use of a novel interferometer.” Optics Letters 26, no. 4 (February 15, 2001): 235–37. https://doi.org/10.1364/OL.26.000235.Full Text
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Müller, M. G., I. Georgakoudi, A. Wax, R. Dasari, C. Jost, M. Wallace, and M. S. Feld. “Multiexcitation fluorescence and reflectance spectroscopy as a real time guide to biopsy in vivo.” Proceedings of Spie the International Society for Optical Engineering 4261 (January 1, 2001): 114–21. https://doi.org/10.1117/12.424525.Full Text
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Wax, A., C. Yang, R. R. Dasari, and M. S. Feld. “Angular light scattering studies using low-coherence interferometry.” Proceedings of Spie the International Society for Optical Engineering 4251 (January 1, 2001): 32–42. https://doi.org/10.1117/12.427903.Full Text
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Yang, C., A. Wax, K. Badizadegan, R. R. Dasari, and M. S. Feld. “Phase-referenced interferometer with subwavelength and subhertz sensitivity.” Optics and Photonics News 12, no. 12 (January 1, 2001): 36. https://doi.org/10.1364/OPN.12.12.000036.Full Text
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Yang, C., A. Wax, R. R. Dasari, and M. S. Feld. “Interferometric phase-based dual wavelength tomography.” Proceedings of Spie the International Society for Optical Engineering 4251 (January 1, 2001): 63–70. https://doi.org/10.1117/12.427872.Full Text
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Yang, C., A. Wax, I. Georgakoudi, E. B. Hanlon, K. Badizadegan, R. R. Dasari, and M. S. Feld. “Interferometric phase-dispersion microscopy.” Optics Letters 25, no. 20 (October 15, 2000): 1526–28. https://doi.org/10.1364/OL.25.001526.Full Text
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Wax, A., S. Bali, and J. E. Thomas. “Time-resolved phase-space distributions for light backscattered from a disordered medium.” Physical Review Letters 85, no. 1 (July 2000): 66–69. https://doi.org/10.1103/physrevlett.85.66.Full Text
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Thomas, John E., Frank Reil, Kim F. Lee, Adam Wax, and Samir Bali. “<title>Wigner phase space distribution and coherence tomography</title>.” Edited by Yehuda B. Band. Spie Proceedings, April 14, 2000. https://doi.org/10.1117/12.382047.Full Text
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Yang, C., L. T. Perelman, A. Wax, R. R. Dasari, and M. S. Feld. “Feasibility of field-based light scattering spectroscopy.” Journal of Biomedical Optics 5, no. 2 (April 2000): 138–43. https://doi.org/10.1117/1.429980.Full Text
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Thomas, J. E., F. Reil, K. F. Lee, A. Wax, and S. Bali. “Wigner phase space distributions and coherence tomography.” Proceedings of Spie the International Society for Optical Engineering 3914 (January 1, 2000): 363–71.
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Wax, A., F. Reil, K. F. Lee, S. Bali, and J. E. Thomas. “Time-resolved optical phase space distributions for coherent backscatter.” Proceedings of Spie the International Society for Optical Engineering 4001 (January 1, 2000): 130–34.
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Lee, K. F., F. Reil, S. Bali, A. Wax, and J. E. Thomas. “Heterodyne measurement of Wigner distributions for classical optical fields.” Optics Letters 24, no. 19 (October 1999): 1370–72. https://doi.org/10.1364/ol.24.001370.Full Text
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Wax, A., S. Bali, G. A. Alphonse, and J. E. Thomas. “Characterizing the Coherence of Broadband Sources using Optical Phase Space Contours.” Journal of Biomedical Optics 4, no. 4 (October 1999): 482–89. https://doi.org/10.1117/1.429961.Full Text
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Wax, A., S. Bali, and J. E. Thomas. “Optical phase-space distributions for low-coherence light.” Optics Letters 24, no. 17 (September 1999): 1188–90. https://doi.org/10.1364/ol.24.001188.Full Text
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Wax, A., and J. E. Thomas. “Measurement of smoothed Wigner phase space distributions for coherence tomography.” Proceedings of Spie the International Society for Optical Engineering 3726 (January 1, 1999): 494–501. https://doi.org/10.1117/12.341431.Full Text
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Wax, A., and J. E. Thomas. “Measurement of smoothed Wigner phase space distributions for coherence tomography.” Proceedings of Spie the International Society for Optical Engineering 3598 (January 1, 1999): 2–9.
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Wax, A., and J. E. Thomas. “Measurement of smoothed Wigner phase-space distributions for small-angle scattering in a turbid medium.” Journal of the Optical Society of America. A, Optics, Image Science, and Vision 15, no. 7 (July 1998): 1896–1908. https://doi.org/10.1364/josaa.15.001896.Full Text
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Wax, A., and J. E. Thomas. “Wigner phase space distributions and optical coherence in turbid media.” Conference Proceedings Lasers and Electro Optics Society Annual Meeting Leos 11 (January 1, 1997): 41.
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Wax, A., and J. E. Thomas. “Optical heterodyne imaging and Wigner phase space distributions.” Optics Letters 21, no. 18 (September 1996): 1427–29. https://doi.org/10.1364/ol.21.001427.Full Text
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Book Sections
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Graf, R. N., F. E. Robles, and A. Wax. “Assessing microscopic structural features using fourier-domain low coherence interferometry.” In Handbook of Biomedical Optics, 463–82, 2016.
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Wax, A., M. Giacomelli, and F. Robles. “Elastic scattering spectroscopy and optical coherence tomography.” In Optical Coherence Tomography: Technology and Applications, Second Edition, 1207–35, 2015. https://doi.org/10.1007/978-3-319-06419-2_39.Full Text
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Zhu, Y., F. E. Robles, N. G. Terry, and A. Wax. “Interferometric light scattering techniques for measuring nuclear morphology and detecting dysplasia.” In Biomedical Photonics Handbook, 653–81, 2014.
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Vo-Dinh, T. “Preface,” ix–xi, 2014. https://doi.org/10.1201/b17289.Full Text
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Wax, A., and F. E. Robles. “Molecular imaging true color spectroscopic (METRiCS) optical coherence tomography.” In Medical Imaging: Technology and Applications, 53–87, 2013. https://doi.org/10.1201/b15511.Full Text
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Conference Papers
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Highland, T., S. M. Parker, H. Price, M. Reynolds, S. He, B. D. Hoffman, and A. Wax. “Combined Quantitative Phase Microscopy and Förster Resonance Energy Transfer Imaging for Analyzing Endothelial Cell Shear Stress Response.” In Optics Infobase Conference Papers, 2022.
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Rancu, A., C. X. Chen, S. Parker, and A. Wax. “Analysis of Disorder Strength Across Quantitative Phase Imaging Systems.” In Optics Infobase Conference Papers, 2022.
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Thakoor, K. A., A. Carter, G. Song, A. Wax, O. Moussa, R. W. S. Chen, C. Hendon, and P. Sajda. “Enhancing Portable OCT Image Quality via GANs for AI-Based Eye Disease Detection.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 13573 LNCS:155–67, 2022. https://doi.org/10.1007/978-3-031-18523-6_15.Full Text
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Chen, Cindy X., Evan T. Jelly, Kengyeh K. Chu, and Adam Wax. “Indocyine Green (ICG) Enhanced Shortwave Infrared Fluorescence Imaging at Video Rate.” In Bio Optics: Design and Application, DM3A-5, 2021.
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Chen, C. X., H. S. Park, and A. Wax. “Breast cell cancer progression characterization through holographic cytometry.” In Optics Infobase Conference Papers, 2021.
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Kendall, Wesley Y., Julianna Bordas, Evan T. Jelly, Babak Mirminachi, Abel Joseph, Jatin Roper, and Adam Wax. “Spectroscopic optical coherence tomography for early detection of colorectal cancer in a mouse model.” In Bio Optics: Design and Application, DF1A-4, 2021.
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Parker, S. M., H. Price, M. Reynolds, S. He, B. D. Hoffman, and A. Wax. “Combined quantitative phase microscopy and förster resonance energy transfer for analyzing cell ion dynamics.” In Optics Infobase Conference Papers, 2021.
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Kendall, W., D. Ho, K. Chu, M. Zinaman, D. Wieland, and A. Wax. “Clinical use of scanning angle-resolved low coherence interferometry for detection of cervical dysplasia.” In Optics Infobase Conference Papers, Vol. Part F178-Translational-2020, 2020.
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Song, G., W. Kendall, Z. A. Steelman, and A. Wax. “Two-dimensional angle-resolved low-coherence interferometry with spatial scanning.” In Optics Infobase Conference Papers, Vol. Part F178-Translational-2020, 2020.
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Wax, A. “Applications of low cost optical coherence tomography.” In Optics Infobase Conference Papers, Vol. Part F180-OCT-2020, 2020.
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Zhang, H., Z. A. Steelman, and A. Wax. “Determination of particle size from reconstructed angular backscattering through a single multimode fiber.” In Optics Infobase Conference Papers, Vol. Part F179-OTS-2020, 2020. https://doi.org/10.1364/OTS.2020.STh4D.4.Full Text
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Jelly, Evan T., Wesley Kendall, Robin Schmitz, Stuart J. Knechtle, Debra L. Sudan, Abel Joseph, Jatin Roper, Jean Kwun, and Adam Wax. “Novel Implementations of Optical Coherence Tomography for Clinical Applications in the Lower Gastrointestinal Tract.” In Optical Coherence Tomography, OTu4E-4, 2020.
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Jelly, E. T., Y. Zhao, K. K. Chu, M. Crose, and A. Wax. “Expanded imaging volume for dual-axis optical coherence tomography.” In Frontiers in Optics Proceedings Frontiers in Optics + Laser Science Aps/Dls, 2019. https://doi.org/10.1364/FIO.2019.FM3C.3.Full Text
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Jelly, Evan T., and Adam Wax. “Arthroscopic Delivery of OCT Using Low-Cost OCT System for Assessment of Porcine Articular Cartilage Thickness.” In Bio Optics: Design and Application, DT2B-4, 2019.
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Zhang, H., Z. A. Steelman, and A. Wax. “Computational reconstruction of angular scattering distributions through an individual multimode fiber.” In Optics Infobase Conference Papers, Vol. Part F168-BODA 2019, 2019. https://doi.org/10.1364/BODA.2019.JW4C.6.Full Text
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Zhao, Y., K. K. Chu, and A. Wax. “Enhanced depth penetration by dual-axis optical coherence tomography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10867, 2019. https://doi.org/10.1117/12.2507242.Full Text
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Jelly, Evan T., Yang Zhao, Kengyeh K. Chu, Michael Crose, and Adam Wax. “Expanded Imaging Volume for Dual-Axis Optical Coherence Tomography.” In Frontiers in Optics, FM3C-3, 2019.
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Ho, D., K. K. Chu, Z. A. Steelman, and A. Wax. “Scanning angle-resolved low coherence interferometry system for clinical detection of cervical dysplasia.” In Optics Infobase Conference Papers, Vol. Part F91-TRANSLATIONAL 2018, 2018. https://doi.org/10.1364/TRANSLATIONAL.2018.CF4B.6.Full Text
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Jelly, Evan T., Yang Zhao, Michael Crose, Sanghoon Kim, Brian Cox, Ge Song, and Adam Wax. “Adaptability and Performance of Low-Cost OCT System for use in Benchtop Optical Coherence Microscopy.” In Optical Tomography and Spectroscopy, JW3A-32, 2018.
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Song, G., S. Kim, M. Crose, B. Cox, W. Brown, and A. Wax. “Design and implementation of a low-cost, portable OCT system.” In Optics Infobase Conference Papers, Vol. Part F90-OTS 2018, 2018. https://doi.org/10.1364/OTS.2018.OF3D.7.Full Text
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Wax, A. “Development of a low-cost, portable optical coherence tomography (OCT) system.” In Optics Infobase Conference Papers, Vol. Part F96-AIO 2018, 2018. https://doi.org/10.1364/AIO.2018.AW2A.4.Full Text
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Zhao, Yang, Kengyeh K. Chu, Will J. Eldridge, Evan T. Jelly, Michael Crose, and Adam Wax. “Speckle Reduction in Optical Coherence Tomography at Video Rate.” In Optical Tomography and Spectroscopy, OF3D-3, 2018.
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Wax, A. “Nanoscale phase imaging of live cells.” In Optics Infobase Conference Papers, Vol. Part F66-FiO 2017, 2017. https://doi.org/10.1364/FIO.2017.FW6D.1.Full Text
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Zhao, Y., J. R. Maher, M. M. Ibrahim, J. S. Chien, H. Levinson, and A. Wax. “In vivo rat skin flap viability assessment using dual axis spectroscopic optical coherence tomography.” In Optics Infobase Conference Papers, Vol. Part F62-BODA 2017, 2017. https://doi.org/10.1364/BODA.2017.BoM4A.4.Full Text
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Kim, S., M. Crose, L. A. Kresty, and A. Wax. “Guidance of angle-resolved low coherence interferometry using co-located optical coherence tomography on rat esophageal tissue.” In Optics Infobase Conference Papers, 2016. https://doi.org/10.1364/TRANSLATIONAL.2016.JTu3A.16.Full Text
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Kim, S., M. Crose, L. A. Kresty, and A. Wax. “Guidance of angle-resolved low coherence interferometry using co-located optical coherence tomography on rat esophageal tissue.” In Optics Infobase Conference Papers, 3, 2016.
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Zhao, Y., J. R. Maher, and A. Wax. “Toward the assessment of blood oxygenation using multispectral multiple scattering low coherence interferometry.” In Optics Infobase Conference Papers, 2016. https://doi.org/10.1364/TRANSLATIONAL.2016.JM3A.24.Full Text
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Zhao, Y., J. R. Maher, and A. Wax. “Toward the assessment of blood oxygenation using multispectral multiple scattering low coherence interferometry.” In Optics Infobase Conference Papers, 3, 2016.
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Wax, A. “Molecular contrast in interferometric imaging.” In Conference on Lasers and Electro Optics Europe Technical Digest, Vol. 2015-August, 2015.
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Eldridge, W. J., A. Sheinfeld, M. T. Rinehart, and A. Wax. “Detecting mechanically induced displacements in human cell cultures using quantitative phase imaging.” In Novel Techniques in Microscopy, Ntm 2015, 2015. https://doi.org/10.1364/ntm.2015.nw3c.5.Full Text
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Maher, J. R., O. Chuchuen, A. D. M. Kashuba, D. F. Katz, and A. Wax. “Combined raman spectroscopy and optical coherence tomography for measuring analytes in targeted tissues.” In Optical Molecular Probes, Imaging and Drug Delivery, Omp 2015, 2015. https://doi.org/10.1364/omp.2015.om3d.3.Full Text
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Zhao, Y., J. R. Maher, H. Levinson, W. J. Brown, and A. Wax. “In vivo burn severity assessment in a mouse model using spectroscopic optical coherence tomography.” In Bio Optics: Design and Application, Boda 2015, 2015. https://doi.org/10.1364/boda.2015.bm4a.3.Full Text
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Eldridge, W. J., B. Loomis, and A. Wax. “Linking cellular disorder strength and shear stiffness using quantitative phase imaging.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/FIO.2016.FF3A.6.Full Text
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Ho, D., T. Drake, K. K. Smith-McCune, T. M. Darragh, L. Y. Hwang, and A. Wax. “Clinical detection of cervical dysplasia using angle-resolved low coherence interferometry.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/CANCER.2016.CTh4A.2.Full Text
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Kim, S., M. Crose, L. A. Kresty, and A. Wax. “Guidance of angle-resolved low coherence interferometry using co-located optical coherence tomography on rat esophageal tissue.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/CANCER.2016.JTu3A.16.Full Text
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Steelman, Z. A., W. J. Eldridge, H. S. Park, and A. Wax. “Corruption of refractive index measurements of spheres using quantitative phase microscopy.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/FIO.2016.JTh2A.126.Full Text
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Zhao, Y., J. R. Maher, and A. Wax. “Toward the assessment of blood oxygenation using multispectral multiple scattering low coherence interferometry.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/CANCER.2016.JM3A.24.Full Text
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Wax, A. “Wigner distribution: Friend to biophotonics.” In Optics Infobase Conference Papers, 2013. https://doi.org/10.1364/fio.2013.fw2d.1.Full Text
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Shaked, N. T., L. L. Satterwhite, M. J. Telen, G. A. Truskey, and A. Wax. “Dynamic quantitative microscopy and nanoscopy of red blood cells in sickle cell disease.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8227, 2012. https://doi.org/10.1117/12.907659.Full Text
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Seekell, K., C. Wilson, H. Price, G. Grant, and A. Wax. “Controlled synthesis of gold nanorods and application to brain tumor delineation.” In Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Real-time quantitative phase and dual-channel fluorescence microscopy for studying cellular and biomolecular dynamics.” In Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Whole-cell analysis of cardiomyocytes with combined quantitative phase and two-channel fluorescence microscopy.” In Optics Infobase Conference Papers, 2011.
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Real-time quantitative phase and dual-channel fluorescence microscopy for studying cellular and biomolecular dynamics.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/ntm.2011.ntub3.Full Text
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Rinehart, M. T., N. T. Shaked, L. Satterwhite, and A. Wax. “Whole-cell analysis of cardiomyocytes with combined quantitative phase and two-channel fluorescence microscopy.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/omp.2011.oma4.Full Text
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Skala, M. C., M. J. Crow, A. Wax, and J. A. Izatt. “Photothermal optical coherence tomography for molecular imaging.” In Optics Infobase Conference Papers, 2011.
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Skala, M. C., M. J. Crow, A. Wax, and J. A. Izatt. “Photothermal optical coherence tomography for molecular imaging.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/omp.2011.otua3.Full Text
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Zhu, Y., N. T. Shaked, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast microscopy.” In Optics Infobase Conference Papers, 2011.
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Zhu, Y., N. T. Shaked, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast microscopy.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/ntm.2011.ntub4.Full Text
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Seekell, K., C. Wilson, H. Price, G. Grant, and A. Wax. “Controlled synthesis of gold nanorods and application to brain tumor delineation.” In Optics Infobase Conference Papers, 2011. https://doi.org/10.1364/fio.2011.fwl4.Full Text
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Wax, A. “Coherence imaging.” In Optics Infobase Conference Papers, 2010. https://doi.org/10.1364/fio.2010.ftuy4.Full Text
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Kim, K. H., T. K. Drake, M. G. DeSoto, M. H. Henderson, D. F. Katz, and A. Wax. “Development of an integrated multiplexed low coherence interferometer and fluorescence clinical endoscope.” In Optics Infobase Conference Papers, 2009. https://doi.org/10.1364/fio.2009.jwc75.Full Text
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Rinehart, M., M. Giacomelli, K. Chalut, and A. Wax. “Quantitative phase microscopy with multi-wavelength unwrapping and tomographic 3d reconstruction.” In Biomedical Optics, Biomed 2008, 2008. https://doi.org/10.1364/biomed.2008.jma7.Full Text
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Wax, A. “Analyzing light scattering from aspherical nuclei for cell biology and clinical applications.” In Optics Infobase Conference Papers, 2008. https://doi.org/10.1364/ls.2008.lthd1.Full Text
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Wax, A., and M. Crow. “Molecular imaging and microspectroscopy of live cells using immunotargeted nanoparticles.” In Optics Infobase Conference Papers, 2007. https://doi.org/10.1364/fio.2007.ftud1.Full Text
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Braun, K. E., J. W. Pyhtila, and A. Wax. “Quantitative characterization of spectrograph entrance slit width on roll-off of fourier domain optical coherence tomography signals.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/bio.2006.tui39.Full Text
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Braun, K. E., and A. Wax. “Improved simulations for measuring microbicidal gel thickness using low-coherence interferometry.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/fio.2006.ftue4.Full Text
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Chalut, K. J., J. W. Pyhtila, and A. Wax. “Improved design of a heterodyne angle-resolved low coherence interferometry system used for new chemoprevention and carcinogenesis studies.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/bio.2006.sh19.Full Text
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Curry, A. C., and A. Wax. “Sensitivity analysis of detecting plasmon resonance spectral shifts for nanoparticle based biosensors.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/fio.2006.ftuk1.Full Text
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Curry, A., and A. Wax. “Epi-illumination darkfield through a microscope objective for imaging and spectral analysis of nanoparticle interaction with cells in culture.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/bio.2006.sf7.Full Text
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Pyhtila, J. W., J. D. Boyer, K. J. Chalut, and A. Wax. “Endoscopic fourier-domain angle-resolved low coherence interferometry for assessing nuclear morphology in human epithelial tissues.” In Optics Infobase Conference Papers, 2006. https://doi.org/10.1364/bio.2006.tud3.Full Text
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Chou, D. R., S. Koh, B. A. Bower, and A. P. Wax. “Low-cost, highly-adaptable, retrofitted laser scanning module for real-time reflectance and confocal fluorescence microscopy.” In Optics Infobase Conference Papers, 2004.
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Pyhtila, J. W., N. G. Terry, and A. Wax. “Experimental calibration of a new angle-resolved low coherence interferometry system.” In Optics Infobase Conference Papers, 2004.
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Wax, A. “Detecting pre-cancerous cells using angle-resolved low coherence interferometry.” In Optics Infobase Conference Papers, 2004.
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Wax, A. “Real-time angle-resolved low-coherence interferometry for detecting pre-cancerous cells.” In Optics Infobase Conference Papers, 2004.
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Backman, V., V. Gopal, M. Kalashnikov, K. Badizadegan, R. Gurjar, A. Wax, I. Georgakoudi, et al. “Measuring Cellular Structure at Submicron Scale with Scattering Angle Sensitive Light Scattering Spectroscopy.” In Optics Infobase Conference Papers, 661–63, 2002.
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Georgakoudi, I., V. Backman, M. Müller, M. Wallace, B. Jacobson, K. Badizadegan, A. Wax, et al. “Diffuse reflectance spectroscopy as an in vivo tool for characterizing changes in tissue organization during neoplastic development.” In Optics Infobase Conference Papers, 649–51, 2002.
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Wax, A., C. Yang, M. Müller, I. Georgakoudi, C. W. Boone, R. R. Dasari, and M. S. Feld. “Structure and organization of cellular components measured in neoplastic tissues using angular low coherence interferometry.” In Optics Infobase Conference Papers, 254–56, 2002.
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Wax, A., C. Yang, R. R. Dasari, and M. S. Feld. “Path-length-resolved dynamic light scattering: modeling the transition from single to diffusive scattering.” In Optics Infobase Conference Papers, 143–45, 2000.
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Wax, A., and J. E. Thomas. “Measurement of Smoothed Wigner Phase Space Distributions in Multiple Scattering Media.” In Optics Infobase Conference Papers, 348–52, 1998.
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Recent Courses
- BME 436L: Biophotonic Instrumentation (DR) 2023
- BME 494: Projects in Biomedical Engineering (GE) 2023
- EGR 491: Projects in Engineering 2023
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- MENG 550: Master of Engineering Internship/Project 2023
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- MENG 550: Master of Engineering Internship/Project 2022
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- PHYSICS 621: Advanced Optics 2022
- BME 550: Modern Microscopy (GE, IM) 2021
- BME 551L: Biomedical Optical Spectroscopy and Tissue Optics (GE, IM) 2021
- BME 791: Graduate Independent Study 2021
- MENG 550: Master of Engineering Internship/Project 2021
- MENG 551: Master of Engineering Internship/Project Assessment 2021
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