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The reference genome sequence of Saccharomyces cerevisiae: then and now.

Publication ,  Journal Article
Engel, SR; Dietrich, FS; Fisk, DG; Binkley, G; Balakrishnan, R; Costanzo, MC; Dwight, SS; Hitz, BC; Karra, K; Nash, RS; Weng, S; Wong, ED ...
Published in: G3 (Bethesda)
March 20, 2014

The genome of the budding yeast Saccharomyces cerevisiae was the first completely sequenced from a eukaryote. It was released in 1996 as the work of a worldwide effort of hundreds of researchers. In the time since, the yeast genome has been intensively studied by geneticists, molecular biologists, and computational scientists all over the world. Maintenance and annotation of the genome sequence have long been provided by the Saccharomyces Genome Database, one of the original model organism databases. To deepen our understanding of the eukaryotic genome, the S. cerevisiae strain S288C reference genome sequence was updated recently in its first major update since 1996. The new version, called "S288C 2010," was determined from a single yeast colony using modern sequencing technologies and serves as the anchor for further innovations in yeast genomic science.

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Published In

G3 (Bethesda)

DOI

EISSN

2160-1836

Publication Date

March 20, 2014

Volume

4

Issue

3

Start / End Page

389 / 398

Location

England

Related Subject Headings

  • User-Computer Interface
  • Sequence Analysis, DNA
  • Saccharomyces cerevisiae
  • Open Reading Frames
  • Internet
  • Genome, Fungal
  • Databases, Factual
  • Chromosome Mapping
  • 4905 Statistics
  • 3105 Genetics
 

Citation

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Engel, S. R., Dietrich, F. S., Fisk, D. G., Binkley, G., Balakrishnan, R., Costanzo, M. C., … Cherry, J. M. (2014). The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda), 4(3), 389–398. https://doi.org/10.1534/g3.113.008995
Engel, Stacia R., Fred S. Dietrich, Dianna G. Fisk, Gail Binkley, Rama Balakrishnan, Maria C. Costanzo, Selina S. Dwight, et al. “The reference genome sequence of Saccharomyces cerevisiae: then and now.G3 (Bethesda) 4, no. 3 (March 20, 2014): 389–98. https://doi.org/10.1534/g3.113.008995.
Engel SR, Dietrich FS, Fisk DG, Binkley G, Balakrishnan R, Costanzo MC, et al. The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda). 2014 Mar 20;4(3):389–98.
Engel, Stacia R., et al. “The reference genome sequence of Saccharomyces cerevisiae: then and now.G3 (Bethesda), vol. 4, no. 3, Mar. 2014, pp. 389–98. Pubmed, doi:10.1534/g3.113.008995.
Engel SR, Dietrich FS, Fisk DG, Binkley G, Balakrishnan R, Costanzo MC, Dwight SS, Hitz BC, Karra K, Nash RS, Weng S, Wong ED, Lloyd P, Skrzypek MS, Miyasato SR, Simison M, Cherry JM. The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda). 2014 Mar 20;4(3):389–398.

Published In

G3 (Bethesda)

DOI

EISSN

2160-1836

Publication Date

March 20, 2014

Volume

4

Issue

3

Start / End Page

389 / 398

Location

England

Related Subject Headings

  • User-Computer Interface
  • Sequence Analysis, DNA
  • Saccharomyces cerevisiae
  • Open Reading Frames
  • Internet
  • Genome, Fungal
  • Databases, Factual
  • Chromosome Mapping
  • 4905 Statistics
  • 3105 Genetics