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How does site of pelvic organ prolapse repair affect overactive bladder symptoms?

Publication ,  Journal Article
Dieter, AA; Edenfield, AL; Weidner, AC; Siddiqui, NY
Published in: Female Pelvic Med Reconstr Surg
2014

OBJECTIVES: To assess how site of pelvic organ prolapse repair affects overactive bladder (OAB) symptoms, we compared change in OAB symptoms in women undergoing isolated anterior/apical (AA) repair versus isolated posterior (P) repair. METHODS: This is a retrospective cohort study of women with bothersome OAB undergoing either AA or P prolapse repair. The subjects completed the Pelvic Floor Distress Inventory short form and the Overactive Bladder Questionnaire (OAB-q) validated questionnaires preoperatively and 6 weeks postoperatively. Our primary outcome was OAB-q symptom severity (SS) change score (preoperative minus postoperative score) compared between the 2 groups. RESULTS: Of 175 subjects, 133 (76%) underwent AA repair and 42 (24%) underwent P repair. Baseline OAB-q SS scores and baseline characteristics were similar except that the AA group had more severe baseline prolapse (median pelvic organ prolapse quantification stage 3 for AA [interquartile range, 2-3] vs stage 2 for P [interquartile range, 1-3]; P<0.01] and a higher rate of concomitant midurethral sling (57% in AA vs 31% in P; P<0.01). Overall OAB symptoms significantly improved within 6 weeks of surgery (P<0.01). The mean ± SD OAB-q SS change score was higher in the AA repair group (26 ± 24 in AA vs 13 ± 28 in P; P=0.01), indicating greater improvement in OAB symptom severity after AA repair. In linear regression adjusting for age, body mass index, diabetes, stress urinary incontinence, pelvic organ prolapse quantification stage, anticholinergic use, and midurethral sling, this difference did not remain significant. CONCLUSIONS: Patients have significant improvement in OAB symptoms after POP repair. In adjusted analyses, there was no difference in improvement in OAB-q SS scores in the patients who had AA versus P repair.

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Published In

Female Pelvic Med Reconstr Surg

DOI

EISSN

2154-4212

Publication Date

2014

Volume

20

Issue

4

Start / End Page

203 / 207

Location

United States

Related Subject Headings

  • Urinary Bladder, Overactive
  • Treatment Outcome
  • Surveys and Questionnaires
  • Suburethral Slings
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Pelvic Organ Prolapse
  • Pelvic Floor
  • Middle Aged
 

Citation

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Dieter, A. A., Edenfield, A. L., Weidner, A. C., & Siddiqui, N. Y. (2014). How does site of pelvic organ prolapse repair affect overactive bladder symptoms? Female Pelvic Med Reconstr Surg, 20(4), 203–207. https://doi.org/10.1097/SPV.0000000000000087
Dieter, Alexis A., Autumn L. Edenfield, Alison C. Weidner, and Nazema Y. Siddiqui. “How does site of pelvic organ prolapse repair affect overactive bladder symptoms?Female Pelvic Med Reconstr Surg 20, no. 4 (2014): 203–7. https://doi.org/10.1097/SPV.0000000000000087.
Dieter AA, Edenfield AL, Weidner AC, Siddiqui NY. How does site of pelvic organ prolapse repair affect overactive bladder symptoms? Female Pelvic Med Reconstr Surg. 2014;20(4):203–7.
Dieter, Alexis A., et al. “How does site of pelvic organ prolapse repair affect overactive bladder symptoms?Female Pelvic Med Reconstr Surg, vol. 20, no. 4, 2014, pp. 203–07. Pubmed, doi:10.1097/SPV.0000000000000087.
Dieter AA, Edenfield AL, Weidner AC, Siddiqui NY. How does site of pelvic organ prolapse repair affect overactive bladder symptoms? Female Pelvic Med Reconstr Surg. 2014;20(4):203–207.

Published In

Female Pelvic Med Reconstr Surg

DOI

EISSN

2154-4212

Publication Date

2014

Volume

20

Issue

4

Start / End Page

203 / 207

Location

United States

Related Subject Headings

  • Urinary Bladder, Overactive
  • Treatment Outcome
  • Surveys and Questionnaires
  • Suburethral Slings
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Pelvic Organ Prolapse
  • Pelvic Floor
  • Middle Aged