Nazema Yusuf Siddiqui | Scholars@Duke

Nazema Yusuf Siddiqui
Associate Professor of Obstetrics and Gynecology

Research on pelvic floor disorders. Specific interests include: 1) pathophysiology of overactive bladder with particular emphasis on epigenetic mechanisms; and 2) studying the urinary microbiome with aging and in women with recurrent urinary tract infection. Additional interests include clinical outcomes research after surgery for prolapse and other pelvic floor disorders.

Current Research Interests

Epigenomics of overactive bladder/urgency urinary incontinence
Urinary microbiome with aging and with recurrent urinary tract infections

Office Hours

8:00AM - 4:30PM Mon-Fri

Current Appointments & Affiliations

Associate Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Urogynecology, Obstetrics and Gynecology 2018

Contact Information

5324 McFarland Drive Suite 310, Box 3912, Durham, NC 27617
Duke University Medical Center, Durham, NC 27617
nazema.siddiqui@duke.edu (919) 401-1000
Clinical Website

Background
Education, Training, & Certifications
- Fellow, Female Pelvic Medicine & Reconstructive Surgery, Obstetrics & Gynecology, Duke University School of Medicine 2007 - 2010
- M.H.S.C.R., Duke University School of Medicine 2010
- Residency, Ob/Gyn, MetroHealth Medical Center, Cleveland Clinic 2002 - 2006
- M.D., University of Michigan at Ann Arbor 2001
Medical Licensure
- 35-087963. North Carolina. 2007
Duke Appointment History
- Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Urogynecology, Obstetrics and Gynecology 2010 - 2018
- Clinical Associate in the Department of Obstetrics and Gynecology, Obstetrics and Gynecology, Clinical Science Departments 2008 - 2010
- Clinical Associate in the Department of Obstetrics and Gynecology, Obstetrics and Gynecology, Clinical Science Departments 2007 - 2008
Leadership & Clinical Positions at Duke
- Director of Research, Division of Urogynecology, Dept of OB/GYN, 2012 - present
Recognition
In the News
- APR 26, 2018 Health.com
  
  9 Home Remedies for Preventing and Treating UTIs
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Advancing the Measurement and Classification of Lower Urinary Tract Dysfunction awarded by National Institutes of Health 2012 - 2024
- Effects of Aging and the Urinary Microbiome on Recurrent Urinary Tract Infections awarded by National Institutes of Health 2018 - 2021
- A Prediction Model and Electronic Calculator for Risk of Obstetric Anal Sphincter Injuries 2019 - 2021
- Duke University Medical Center (DUMC) Pelvic Floor Disorders Network (PFDN) Clinical Site awarded by National Institutes of Health 2007 - 2021
- Effects of Aging and the Urinary Microbiome on Recurrent Urinary Tract Infections awarded by National Institutes of Health 2018 - 2020
- Epigenomics in insulin resistance associated overactive bladder awarded by National Institutes of Health 2017 - 2020
- Fundamentals of Robotic Surgery: Curriculum and Technical Validation Skills 2014 - 2016
- Sexual Function in Patients and Partners after Surgery for Pelvic Organ Prolapse awarded by Josiah Charles Trent Memorial Foundation 2009
Fellowships, Supported Research, & Other Grants
- Pepper OAIC Research Career Development Award awarded by NIA/Duke School of Medicine 2018 - 2020
- Duke Scholar awarded by Doris Duke Fund to Retain Clinical Scientists 2018
- K23 Mentored Patient-Oriented Career Development Award awarded by NIDDK 2017 - 2020
- Advancing the Measurement and Classification of Lower Urinary Tract Dysfunction awarded by NIH 2016 - 2018
- Urinary methylation patterns in women with bladder pain syndrome awarded by Charles B. Hammond Fund, Duke OB/GYN 2015 - 2016
- Health Disparities Loan Repayment Program awarded by NIH/NCMHD 2013 - 2015
- Post-Approval Network Registry awarded by Medtronic, Inc. 2013 - 2018
- Multidisciplinary K12 for Benign Urologic Research awarded by NIDDK/Duke 2013 - 2017
- Advancing the Measurement and Classification of Lower Urinary Tract Dysfunction awarded by NIH 2012 - 2018
- Health Disparities Loan Repayment Program awarded by NIH/NCMHD 2011 - 2013
- Health seeking behaviors in racially diverse women with urinary incontinence awarded by American Urogynecologic Society Foundation 2011 - 2013
- Relationships of neural structures and uterosacral ligament suspension sutures awarded by Astellas USA Foundation 2008 - 2010
Industry Relationships
- Medtronic (Covidien)
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Siddiqui, Nazema Y., Brian T. Helfand, Victor P. Andreev, Joseph T. Kowalski, Megan S. Bradley, H Henry Lai, Mitchell B. Berger, et al. “Biomarkers Implicated in Lower Urinary Tract Symptoms: Systematic Review and Pathway Analyses..” J Urol 202, no. 5 (November 2019): 880–89. https://doi.org/10.1097/JU.0000000000000257.
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  - Brubaker, Linda, J Eric Jelovsek, Emily S. Lukacz, Sunil Balgobin, Alicia Ballard, Alison C. Weidner, Marie G. Gantz, Ryan Whitworth, Donna Mazloomdoost, and Donna Eunice Kennedy Shriver National Institute of Child Health and Human Development Pelvic Floor Disorders Network. “Recruitment and retention: A randomized controlled trial of video-enhanced versus standard consent processes within the E-OPTIMAL study..” Clin Trials 16, no. 5 (October 2019): 481–89. https://doi.org/10.1177/1740774519865541.
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  - Jelovsek, J Eric, Alayne D. Markland, William E. Whitehead, Matthew D. Barber, Diane K. Newman, Rebecca G. Rogers, Keisha Dyer, et al. “Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial..” Lancet Gastroenterol Hepatol 4, no. 9 (September 2019): 698–710. https://doi.org/10.1016/S2468-1253(19)30193-1.
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  - Komesu, Yuko M., Darrell L. Dinwiddie, Holly E. Richter, Emily S. Lukacz, Vivian W. Sung, Nazema Y. Siddiqui, Halina M. Zyczynski, et al. “Defining the relationship between vaginal and urinary microbiomes..” Am J Obstet Gynecol, August 14, 2019. https://doi.org/10.1016/j.ajog.2019.08.011.
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  - Bickhaus, Jennifer A., Megan S. Bradley, Cindy L. Amundsen, Anthony G. Visco, Tracy Truong, Yi-Ju Li, and Nazema Y. Siddiqui. “Does a Recent Urinary Tract Infection Increase the Risk of Postprocedure Urinary Tract Infection After Onabotulinum Toxin A?.” Female Pelvic Med Reconstr Surg, July 8, 2019. https://doi.org/10.1097/SPV.0000000000000753.
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  - Helfand, Brian T., Victor P. Andreev, Nazema Y. Siddiqui, Gang Liu, Bradley A. Erickson, Margaret E. Helmuth, Susan K. Lutgendorf, H Henry Lai, Ziya Kirkali, and Ziya LURN Study Group. “A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study..” Urology 129 (July 2019): 35–42. https://doi.org/10.1016/j.urology.2019.03.014.
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  - Meekins, A Rebecca, Susan K. Murphy, Carole Grenier, Zhiqing Huang, Megan S. Bradley, Cindy L. Amundsen, Jennifer Wu, and Nazema Y. Siddiqui. “Role of β-3 adrenergic receptor polymorphism in overactive bladder..” Neurourol Urodyn 38, no. 5 (June 2019): 1261–65. https://doi.org/10.1002/nau.24006.
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  - Komesu, Yuko M., Holly E. Richter, Benjamin Carper, Darrell L. Dinwiddie, Emily S. Lukacz, Nazema Y. Siddiqui, Vivian W. Sung, et al. “The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls..” Int Urogynecol J 29, no. 12 (December 2018): 1785–95. https://doi.org/10.1007/s00192-018-3683-6.
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  - Cameron, Anne P., Abigail R. Smith, H Henry Lai, Catherine S. Bradley, Alice B. Liu, Robert M. Merion, Brenda W. Gillespie, et al. “Bowel function, sexual function, and symptoms of pelvic organ prolapse in women with and without urinary incontinence..” Neurourol Urodyn 37, no. 8 (November 2018): 2586–96. https://doi.org/10.1002/nau.23587.
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  - Askew, Amy L., Anthony G. Visco, Alison C. Weidner, Tracy Truong, Nazema Y. Siddiqui, and Megan S. Bradley. “Does Mesh Weight Affect Time to Failure After Robotic-Assisted Laparoscopic Sacrocolpopexy?.” Female Pelvic Med Reconstr Surg, October 12, 2018. https://doi.org/10.1097/SPV.0000000000000632.
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  - Siddiqui, Nazema Y., Jonathan B. Wiseman, David Cella, Catherine S. Bradley, H Henry Lai, Margaret E. Helmuth, Abigail R. Smith, et al. “Mental Health, Sleep and Physical Function in Treatment Seeking Women with Urinary Incontinence..” J Urol 200, no. 4 (October 2018): 848–55. https://doi.org/10.1016/j.juro.2018.04.076.
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  - Vaughan, Monique H., Nazema Y. Siddiqui, Laura K. Newcomb, Alison C. Weidner, Amie Kawasaki, Anthony G. Visco, and Megan S. Bradley. “Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension..” Obstet Gynecol 131, no. 6 (June 2018): 1137–44. https://doi.org/10.1097/AOG.0000000000002593.
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  - Newcomb, Laura K., Megan S. Bradley, Tracy Truong, Michelle Tang, Bryan Comstock, Yi-Ju Li, Anthony G. Visco, and Nazema Y. Siddiqui. “Correlation of Virtual Reality Simulation and Dry Lab Robotic Technical Skills..” J Minim Invasive Gynecol 25, no. 4 (May 2018): 689–96. https://doi.org/10.1016/j.jmig.2017.11.006.
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  - Bradley, Megan S., Emily E. Burke, Carole Grenier, Cindy L. Amundsen, Susan K. Murphy, and Nazema Y. Siddiqui. “A genome-scale DNA methylation study in women with interstitial cystitis/bladder pain syndrome..” Neurourol Urodyn 37, no. 4 (April 2018): 1485–93. https://doi.org/10.1002/nau.23489.
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  - Cameron, Anne P., Christina Lewicky-Gaupp, Abigail R. Smith, Brian T. Helfand, John L. Gore, J Quentin Clemens, Claire C. Yang, et al. “Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study..” J Urol 199, no. 4 (April 2018): 1023–31. https://doi.org/10.1016/j.juro.2017.10.035.
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  - Helmuth, Margaret E., Abigail R. Smith, Victor P. Andreev, Gang Liu, Gang LURN Study Group, H Henry Lai, Anne P. Cameron, and Nazema Y. Siddiqui. “Use of Euclidean length to measure urinary incontinence severity based on the lower urinary tract symptoms tool..” American Journal of Obstetrics and Gynecology 218, no. 3 (March 2018): 357–59. https://doi.org/10.1016/j.ajog.2017.12.219.
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  - Arya, Lily A., Holly E. Richter, Eric Jelovsek, Marie Gantz, Sara Cichowski, Halina Zyczynski, Keisha Dyer, et al. “Metabolites and microbial composition of stool of women with fecal incontinence: Study design and methods..” Neurourol Urodyn 37, no. 2 (February 2018): 634–41. https://doi.org/10.1002/nau.23360.
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  - Komesu, Yuko M., Cindy L. Amundsen, Holly E. Richter, Stephen W. Erickson, Mary F. Ackenbom, Uduak U. Andy, Vivian W. Sung, et al. “Refractory urgency urinary incontinence treatment in women: impact of age on outcomes and complications..” Am J Obstet Gynecol 218, no. 1 (January 2018): 111.e1-111.e9. https://doi.org/10.1016/j.ajog.2017.10.006.
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  - Meekins, A Rebecca, Nazema Y. Siddiqui, Cindy L. Amundsen, Maragatha Kuchibhatla, and Alexis A. Dieter. “Improving Postoperative Efficiency: An Algorithm for Expedited Void Trials After Urogynecologic Surgery..” South Med J 110, no. 12 (December 2017): 785–90. https://doi.org/10.14423/SMJ.0000000000000733.
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  - Weidner, Alison C., Matthew D. Barber, Alayne Markland, David D. Rahn, Yvonne Hsu, Elizabeth R. Mueller, Sharon Jakus-Waldman, et al. “Perioperative Behavioral Therapy and Pelvic Muscle Strengthening Do Not Enhance Quality of Life After Pelvic Surgery: Secondary Report of a Randomized Controlled Trial..” Phys Ther 97, no. 11 (November 1, 2017): 1075–83. https://doi.org/10.1093/ptj/pzx077.
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  - Ju, Rujin, Nazema Siddiqui, Joanne Garrett, Liping Feng, and Michael Heit. “A validated translation of a survey for measuring incontinence knowledge in Chinese-speaking American immigrants..” Int Urogynecol J 28, no. 6 (June 2017): 851–56. https://doi.org/10.1007/s00192-016-3215-1.
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  - Polin, Michael R., Amie Kawasaki, Cindy L. Amundsen, Alison C. Weidner, and Nazema Y. Siddiqui. “Do Mixed-Flora Preoperative Urine Cultures Matter?.” South Med J 110, no. 6 (June 2017): 426–29. https://doi.org/10.14423/SMJ.0000000000000659.
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  - Komesu, Yuko M., Holly E. Richter, Darrell L. Dinwiddie, Nazema Y. Siddiqui, Vivian W. Sung, Emily S. Lukacz, Beri Ridgeway, et al. “Methodology for a vaginal and urinary microbiome study in women with mixed urinary incontinence..” Int Urogynecol J 28, no. 5 (May 2017): 711–20. https://doi.org/10.1007/s00192-016-3165-7.
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  - Edenfield, A. L., N. Y. Siddiqui, J. M. Wu, A. A. Dieter, M. A. Garrett, and A. G. Visco. “Polyethylene glycol 3350 and docusate sodium compared with docusate sodium alone after urogynecologic surgery: A randomized controlled trial.” Obstetrical and Gynecological Survey 71, no. 12 (December 1, 2016): 710–11. https://doi.org/10.1097/01.ogx.0000508192.29563.8f.
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  - Polin, Michael R., Nazema Y. Siddiqui, Bryan A. Comstock, Helai Hesham, Casey Brown, Thomas S. Lendvay, and Martin A. Martino. “Crowdsourcing: a valid alternative to expert evaluation of robotic surgery skills..” Am J Obstet Gynecol 215, no. 5 (November 2016): 644.e1-644.e7. https://doi.org/10.1016/j.ajog.2016.06.033.
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  - Sung, Vivian W., Diane Borello-France, Gena Dunivan, Marie Gantz, Emily S. Lukacz, Pamela Moalli, Diane K. Newman, et al. “Methods for a multicenter randomized trial for mixed urinary incontinence: rationale and patient-centeredness of the ESTEEM trial..” Int Urogynecol J 27, no. 10 (October 2016): 1479–90. https://doi.org/10.1007/s00192-016-3031-7.
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  - Edenfield, Autumn L., Nazema Y. Siddiqui, Jennifer M. Wu, Alexis A. Dieter, Melissa A. Garrett, and Anthony G. Visco. “Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial..” Obstet Gynecol 128, no. 3 (September 2016): 543–49. https://doi.org/10.1097/AOG.0000000000001565.
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  - Siddiqui, Nazema Y., Natalie Ammarell, Jennifer M. Wu, Juan S. Sandoval, and Hayden B. Bosworth. “Urinary Incontinence and Health-Seeking Behavior Among White, Black, and Latina Women..” Female Pelvic Med Reconstr Surg 22, no. 5 (September 2016): 340–45. https://doi.org/10.1097/SPV.0000000000000286.
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  - Yang, Claire C., Kevin P. Weinfurt, Robert M. Merion, Ziya Kirkali, and Ziya LURN Study Group. “Symptoms of Lower Urinary Tract Dysfunction Research Network..” J Urol 196, no. 1 (July 2016): 146–52. https://doi.org/10.1016/j.juro.2016.01.007.
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  - Siddiqui, Nazema Y., Megan E. Tarr, Elizabeth J. Geller, Arnold P. Advincula, Michael L. Galloway, Isabel C. Green, Hye-Chun Hur, Michael C. Pitter, Emily E. Burke, and Martin A. Martino. “Establishing Benchmarks For Minimum Competence With Dry Lab Robotic Surgery Drills..” J Minim Invasive Gynecol 23, no. 4 (May 2016): 633–38. https://doi.org/10.1016/j.jmig.2016.03.014.
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  - Bradley, Megan S., Marcella G. Willis-Gray, Cindy L. Amundsen, and Nazema Y. Siddiqui. “Microhematuria in Postmenopausal Women: Adherence to Guidelines in a Tertiary Care Setting..” J Urol 195, no. 4 Pt 1 (April 2016): 937–41. https://doi.org/10.1016/j.juro.2015.10.136.
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  - Polin, M. R., N. Y. Siddiqui, C. Brown, H. Hesham, B. A. Comstock, T. S. Lendvay, and M. A. Martino. “Crowdsourcing: A Valid Alternative to Expert Evaluation of Robotic Surgery Skills..” J Minim Invasive Gynecol 22, no. 6S (November 2015): S19–20. https://doi.org/10.1016/j.jmig.2015.08.062.
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  - Eric Jelovsek, J., Alayne D. Markland, William E. Whitehead, Matthew D. Barber, Diane K. Newman, Rebecca G. Rogers, Keisha Dyer, et al. “Controlling anal incontinence in women by performing anal exercises with biofeedback or loperamide (CAPABLe) trial: Design and methods..” Contemp Clin Trials 44 (September 2015): 164–74. https://doi.org/10.1016/j.cct.2015.08.009.
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  - Edenfield, Autumn L., Cindy L. Amundsen, Jennifer M. Wu, Pamela J. Levin, and Nazema Y. Siddiqui. “Posterior tibial nerve stimulation for the treatment of fecal incontinence: a systematic evidence review..” Obstet Gynecol Surv 70, no. 5 (May 2015): 329–41. https://doi.org/10.1097/OGX.0000000000000171.
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  - Siddiqui, N. Y., C. L. Grimes, E. R. Casiano, H. T. Abed, P. C. Jeppson, C. K. Olivera, T. V. Sanses, et al. “Mesh sacrocolpopexy compared with native tissue vaginal repair: A systematic review and Meta-analysis.” Obstetrical and Gynecological Survey 70, no. 4 (April 22, 2015): 250–51. https://doi.org/10.1097/01.ogx.0000464936.04266.34.
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  - Koch, Marianne, Rufus Cartwright, Kari A. O. Tikkinen, Nazema Y. Siddiqui, Bruna M. Couri, William Gibson, Paula Igualada-Martinez, and Christopher R. Chapple. “What was hot at the ICS meeting 2014?.” Neurourol Urodyn 34, no. 3 (March 2015): 206–12. https://doi.org/10.1002/nau.22734.
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  - Willis-Gray, Marcella G., Juan S. Sandoval, Jean Maynor, Hayden B. Bosworth, and Nazema Y. Siddiqui. “Barriers to urinary incontinence care seeking in White, Black, and Latina women..” Female Pelvic Med Reconstr Surg 21, no. 2 (March 2015): 83–86. https://doi.org/10.1097/SPV.0000000000000100.
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  - Edenfield, Autumn L., Pamela J. Levin, Alexis A. Dieter, Cindy L. Amundsen, and Nazema Y. Siddiqui. “Sexual activity and vaginal topography in women with symptomatic pelvic floor disorders..” J Sex Med 12, no. 2 (February 2015): 416–23. https://doi.org/10.1111/jsm.12716.
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  - Siddiqui, Nazema Y., Cara L. Grimes, Elizabeth R. Casiano, Husam T. Abed, Peter C. Jeppson, Cedric K. Olivera, Tatiana V. Sanses, et al. “Mesh sacrocolpopexy compared with native tissue vaginal repair: a systematic review and meta-analysis..” Obstet Gynecol 125, no. 1 (January 2015): 44–55. https://doi.org/10.1097/AOG.0000000000000570.
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  - Siddiqui, Nazema Y., Laura G. DuBois, Lisa St John-Williams, Thompson J. Will, Carole Grenier, Emily Burke, Matthew O. Fraser, Cindy L. Amundsen, and Susan K. Murphy. “Optimizing Urine Processing Protocols for Protein and Metabolite Detection..” J Proteomics Bioinform 2015, no. Suppl 14 (2015).
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  - Jelovsek, John Eric, Zhen Chen, Alayne D. Markland, Linda Brubaker, Keisha Y. Dyer, Susie Meikle, David D. Rahn, Nazeema Y. Siddiqui, Ashok Tuteja, and Matthew D. Barber. “Minimum important differences for scales assessing symptom severity and quality of life in patients with fecal incontinence..” Female Pelvic Med Reconstr Surg 20, no. 6 (November 2014): 342–48. https://doi.org/10.1097/SPV.0000000000000078.
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  - Siddiqui, Nazema Y., and Samantha M. Thomas. “In reply..” Obstet Gynecol 124, no. 4 (October 2014). https://doi.org/10.1097/AOG.0000000000000488.
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  - Dieter, Alexis A., Autumn L. Edenfield, Alison C. Weidner, Pamela J. Levin, and Nazema Y. Siddiqui. “Does concomitant anterior/apical repair during midurethral sling improve the overactive bladder component of mixed incontinence?.” Int Urogynecol J 25, no. 9 (September 2014): 1269–75. https://doi.org/10.1007/s00192-014-2400-3.
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  - Levin, Pamela June, Nazema Yusuf Siddiqui, Jennifer Marie Wu, and Cindy Louise Amundsen. “Psychosocial factors related to the use of InterStim® for the treatment of refractory overactive bladder..” Female Pelvic Med Reconstr Surg 20, no. 5 (September 2014): 272–75. https://doi.org/10.1097/SPV.0000000000000062.
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  - Dieter, Alexis A., Autumn L. Edenfield, Alison C. Weidner, and Nazema Y. Siddiqui. “How does site of pelvic organ prolapse repair affect overactive bladder symptoms?.” Female Pelvic Med Reconstr Surg 20, no. 4 (July 2014): 203–7. https://doi.org/10.1097/SPV.0000000000000087.
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  - Siddiqui, Nazema Y., Pamela J. Levin, Amruta Phadtare, Ricardo Pietrobon, and Natalie Ammarell. “Perceptions about female urinary incontinence: a systematic review..” Int Urogynecol J 25, no. 7 (July 2014): 863–71. https://doi.org/10.1007/s00192-013-2276-7.
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  - Siddiqui, Nazema Y., Michael L. Galloway, Elizabeth J. Geller, Isabel C. Green, Hye-Chun Hur, Kyle Langston, Michael C. Pitter, Megan E. Tarr, and Martin A. Martino. “Validity and reliability of the robotic Objective Structured Assessment of Technical Skills..” Obstet Gynecol 123, no. 6 (June 2014): 1193–99. https://doi.org/10.1097/AOG.0000000000000288.
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  - Sung, Vivian W., Rebecca G. Rogers, Carla M. Bann, Lily Arya, Matthew D. Barber, Jerry Lowder, Emily S. Lukacz, et al. “Symptom outcomes important to women with anal incontinence: a conceptual framework..” Obstet Gynecol 123, no. 5 (May 2014): 1023–30. https://doi.org/10.1097/AOG.0000000000000236.
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  - Walter, Paige J., Alexis A. Dieter, Nazema Y. Siddiqui, Alison C. Weidner, and Jennifer M. Wu. “Perioperative anticholinergic medications and risk of catheterization after urogynecologic surgery..” Female Pelvic Med Reconstr Surg 20, no. 3 (May 2014): 163–67. https://doi.org/10.1097/SPV.0000000000000075.
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  - Edenfield, Autumn L., Pamela J. Levin, Alexis A. Dieter, Jennifer M. Wu, and Nazema Y. Siddiqui. “Is postoperative bowel function related to posterior compartment prolapse repair?.” Female Pelvic Med Reconstr Surg 20, no. 2 (March 2014): 90–94. https://doi.org/10.1097/SPV.0000000000000048.
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  - Zimmern, Philippe, Heather Litman, Charles Nager, Larry Sirls, Stephen R. Kraus, Kimberly Kenton, Tracey Wilson, et al. “Pre-operative urodynamics in women with stress urinary incontinence increases physician confidence, but does not improve outcomes..” Neurourol Urodyn 33, no. 3 (March 2014): 302–6. https://doi.org/10.1002/nau.22398.
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  - Jelovsek, J Eric, Kevin Chagin, Linda Brubaker, Rebecca G. Rogers, Holly E. Richter, Lily Arya, Matthew D. Barber, et al. “A model for predicting the risk of de novo stress urinary incontinence in women undergoing pelvic organ prolapse surgery..” Obstet Gynecol 123, no. 2 Pt 1 (February 2014): 279–87. https://doi.org/10.1097/AOG.0000000000000094.
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  - Dieter, Alexis A., Cindy L. Amundsen, Autumn L. Edenfield, Amie Kawasaki, Pamela J. Levin, Anthony G. Visco, and Nazema Y. Siddiqui. “Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial..” Obstet Gynecol 123, no. 1 (January 2014): 96–103. https://doi.org/10.1097/AOG.0000000000000024.
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  - Siddiqui, N. Y. “Commentary on 'Sex after surgery-what should we tell our patients?'.” Bjog: An International Journal of Obstetrics and Gynaecology 121, no. 1 (January 1, 2014). https://doi.org/10.1111/1471-0528.12412.
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  - Siddiqui, Nazema Y., and Autumn L. Edenfield. “Clinical challenges in the management of vaginal prolapse..” Int J Womens Health 6 (2014): 83–94. https://doi.org/10.2147/IJWH.S54845.
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  - Kawasaki, Amie, John P. Judd, Nazema Y. Siddiqui, Jennifer M. Wu, and Cindy L. Amundsen. “Impact of staged InterStim implantation on the postoperative activities of daily living and pain..” Int Urogynecol J 24, no. 7 (July 2013): 1205–13. https://doi.org/10.1007/s00192-012-1965-y.
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  - Kawasaki, Amie, Elizabeth G. Corey, Robin A. Laskey, Alison C. Weidner, Nazema Y. Siddiqui, and Jennifer M. Wu. “Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy..” J Reprod Med 58, no. 5–6 (May 2013): 195–99.
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  - Kawasaki, Amie, Autumn L. Edenfield, Anthony G. Visco, Jennifer M. Wu, Daniel Westreich, and Nazema Y. Siddiqui. “Comparing the risk of urethrolysis for the treatment of voiding dysfunction between two retropubic mesh slings: a case-control study..” Int Urogynecol J 24, no. 4 (April 2013): 589–94. https://doi.org/10.1007/s00192-012-1920-y.
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  - Edenfield, Autumn L., Cindy L. Amundsen, Alison C. Weidner, Jennifer M. Wu, Amy George, and Nazema Y. Siddiqui. “Vaginal prolapse recurrence after uterosacral ligament suspension in normal-weight compared with overweight and obese women..” Obstet Gynecol 121, no. 3 (March 2013): 554–59. https://doi.org/10.1097/AOG.0b013e3182839eeb.
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  - Matteson, Kristen A., David D. Rahn, Thomas L. Wheeler, Elizabeth Casiano, Nazema Y. Siddiqui, Heidi S. Harvie, Mamta M. Mamik, Ethan M. Balk, Vivian W. Sung, and Vivian W. Society of Gynecologic Surgeons Systematic Review Group. “Nonsurgical management of heavy menstrual bleeding: a systematic review..” Obstet Gynecol 121, no. 3 (March 2013): 632–43. https://doi.org/10.1097/AOG.0b013e3182839e0e.
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  - Murphy, Miles, Cedric Olivera, Thomas Wheeler, Elizabeth Casiano, Nazema Siddiqui, Rajiv Gala, Tondalaya Gamble, Ethan M. Balk, and Vivian W. Sung. “Postoperative management and restrictions for female pelvic surgery: a systematic review..” Int Urogynecol J 24, no. 2 (February 2013): 185–93. https://doi.org/10.1007/s00192-012-1898-5.
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  - Jonsson Funk, Michele, Nazema Y. Siddiqui, Virginia Pate, Cindy L. Amundsen, and Jennifer M. Wu. “Sling revision/removal for mesh erosion and urinary retention: long-term risk and predictors..” Am J Obstet Gynecol 208, no. 1 (January 2013): 73.e1-73.e7. https://doi.org/10.1016/j.ajog.2012.10.006.
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  - Jonsson Funk, Michele, Nazema Y. Siddiqui, Amie Kawasaki, and Jennifer M. Wu. “Long-term outcomes after stress urinary incontinence surgery..” Obstet Gynecol 120, no. 1 (July 2012): 83–90. https://doi.org/10.1097/AOG.0b013e318258fbde.
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  - Kawasaki, Amie, Jennifer M. Wu, Cindy L. Amundsen, Alison C. Weidner, John P. Judd, Ethan M. Balk, and Nazema Y. Siddiqui. “Do urodynamic parameters predict persistent postoperative stress incontinence after midurethral sling? A systematic review..” Int Urogynecol J 23, no. 7 (July 2012): 813–22. https://doi.org/10.1007/s00192-012-1693-3.
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  - Levin, Pamela June, Jennifer M. Wu, Nazema Y. Siddiqui, and Cindy L. Amundsen. “Does obesity impact the success of an InterStim test phase for the treatment of refractory urge urinary incontinence in female patients?.” Female Pelvic Med Reconstr Surg 18, no. 4 (July 2012): 243–46. https://doi.org/10.1097/SPV.0b013e31826150fe.
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  - Siddiqui, Nazema Y., Rebekah G. Fulton, Maragatha Kuchibhatla, and Jennifer M. Wu. “Sexual function after vaginal versus nonvaginal prolapse surgery..” Female Pelvic Med Reconstr Surg 18, no. 4 (July 2012): 239–42. https://doi.org/10.1097/SPV.0b013e31825ead35.
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  - Dieter, Alexis A., Cindy L. Amundsen, Anthony G. Visco, and Nazema Y. Siddiqui. “Treatment for urinary tract infection after midurethral sling: a retrospective study comparing patients who receive short-term postoperative catheterization and patients who pass a void trial on the day of surgery..” Female Pelvic Med Reconstr Surg 18, no. 3 (May 2012): 175–78. https://doi.org/10.1097/SPV.0b013e3182544e03.
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  - Siddiqui, Nazema Y., Elizabeth J. Geller, and Anthony G. Visco. “Symptomatic and anatomic 1-year outcomes after robotic and abdominal sacrocolpopexy..” Am J Obstet Gynecol 206, no. 5 (May 2012): 435.e1-435.e5. https://doi.org/10.1016/j.ajog.2012.01.035.
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  - Bradley, Sarah L., Alison C. Weidner, Nazema Y. Siddiqui, Mihir P. Gandhi, and Jennifer M. Wu. “Shifts in national rates of inpatient prolapse surgery emphasize current coding inadequacies..” Female Pelvic Med Reconstr Surg 17, no. 4 (July 2011): 204–8. https://doi.org/10.1097/SPV.0b013e3182254cf1.
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  - Siddiqui, Nazema Y., Cindy L. Amundsen, Elizabeth G. Corey, and Jennifer M. Wu. “Lead migration after sacral neuromodulation: surgical revision in fascial versus tined anchoring systems..” Int Urogynecol J 22, no. 4 (April 2011): 419–23. https://doi.org/10.1007/s00192-010-1285-z.
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  - Kane, Sarah M., Nazema Y. Siddiqui, Jennifer Bailit, and May Hsieh Blanchard. “Duty hour restrictions, ambulatory experience, and surgical procedural volume in obstetrics and gynecology..” J Grad Med Educ 2, no. 4 (December 2010): 530–35. https://doi.org/10.4300/JGME-D-10-00076.1.
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  - Siddiqui, Nazema Y., Terence R. T. Mitchell, Rex C. Bentley, and Alison C. Weidner. “Neural entrapment during uterosacral ligament suspension: an anatomic study of female cadavers..” Obstet Gynecol 116, no. 3 (September 2010): 708–13. https://doi.org/10.1097/AOG.0b013e3181ec658a.
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  - Judd, John P., Nazema Y. Siddiqui, Jason C. Barnett, Anthony G. Visco, Laura J. Havrilesky, and Jennifer M. Wu. “Cost-minimization analysis of robotic-assisted, laparoscopic, and abdominal sacrocolpopexy..” J Minim Invasive Gynecol 17, no. 4 (July 2010): 493–99. https://doi.org/10.1016/j.jmig.2010.03.011.
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  - Bradley, C. S., D. D. Rahn, I. E. Nygaard, M. D. Barber, C. W. Nager, K. S. Kenton, N. Y. Siddiqui, R. B. Abel, C. Spino, and H. E. Richter. “The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence..” Neurourology and Urodynamics 29, no. 5 (June 1, 2010): 727–34.
  - Bradley, Catherine S., David D. Rahn, Ingrid E. Nygaard, Matthew D. Barber, Charles W. Nager, Kimberly S. Kenton, Nazema Y. Siddiqui, Robert B. Abel, Cathie Spino, and Holly E. Richter. “The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence..” Neurourol Urodyn 29, no. 5 (June 2010): 727–34. https://doi.org/10.1002/nau.20818.
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  - Siddiqui, Nazema Y., Jennifer M. Wu, and Cindy L. Amundsen. “Efficacy and adverse events of sacral nerve stimulation for overactive bladder: A systematic review..” Neurourol Urodyn 29 Suppl 1 (2010): S18–23. https://doi.org/10.1002/nau.20786.
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  - Siddiqui, Nazema Y., Cindy L. Amundsen, Anthony G. Visco, Evan R. Myers, and Jennifer M. Wu. “Cost-effectiveness of sacral neuromodulation versus intravesical botulinum A toxin for treatment of refractory urge incontinence..” J Urol 182, no. 6 (December 2009): 2799–2804. https://doi.org/10.1016/j.juro.2009.08.031.
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  - Wu, Jennifer M., Nazema Y. Siddiqui, Cindy L. Amundsen, Evan R. Myers, Laura J. Havrilesky, and Anthony G. Visco. “Cost-effectiveness of botulinum toxin a versus anticholinergic medications for idiopathic urge incontinence..” J Urol 181, no. 5 (May 2009): 2181–86. https://doi.org/10.1016/j.juro.2009.01.037.
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  - Geller, Elizabeth J., Nazema Y. Siddiqui, Jennifer M. Wu, and Anthony G. Visco. “Short-term outcomes of robotic sacrocolpopexy compared with abdominal sacrocolpopexy..” Obstet Gynecol 112, no. 6 (December 2008): 1201–6. https://doi.org/10.1097/AOG.0b013e31818ce394.
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  - Siddiqui, Nazema Y., Kevin J. Stepp, Susan J. Lasch, Jeffrey M. Mangel, and Jennifer M. Wu. “Objective structured assessment of technical skills for repair of fourth-degree perineal lacerations..” Am J Obstet Gynecol 199, no. 6 (December 2008): 676.e1-676.e6. https://doi.org/10.1016/j.ajog.2008.07.054.
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  - Tilburt, Jon C., Rajesh S. Mangrulkar, Susan Dorr Goold, Nazema Y. Siddiqui, and Joseph A. Carrese. “Do we practice what we preach? A qualitative assessment of resident-preceptor interactions for adherence to evidence-based practice..” J Eval Clin Pract 14, no. 5 (October 2008): 780–84. https://doi.org/10.1111/j.1365-2753.2008.00966.x.
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  - Tilburt, Jon C., Susan D. Goold, Nazema Siddiqui, and Rajesh S. Mangrulkar. “How do doctors use information in real-time? A qualitative study of internal medicine resident precepting..” J Eval Clin Pract 13, no. 5 (October 2007): 772–80. https://doi.org/10.1111/j.1365-2753.2006.00752.x.
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  - Siddiqui, Nazema Y., and Marie Fidela R. Paraiso. “Vesicovaginal fistula due to an unreported foreign body in an adolescent..” J Pediatr Adolesc Gynecol 20, no. 4 (August 2007): 253–55. https://doi.org/10.1016/j.jpag.2006.10.003.
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  - Stepp, Kevin J., Nazema Y. Siddiqui, Stephen P. Emery, and Matthew D. Barber. “Textbook recommendations for preventing and treating perineal injury at vaginal delivery..” Obstet Gynecol 107, no. 2 Pt 1 (February 2006): 361–66. https://doi.org/10.1097/01.AOG.0000196502.33265.a4.
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  - Bachman, N. J., P. K. Riggs, N. Siddiqui, G. J. Makris, J. E. Womack, and M. I. Lomax. “Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle..” Genomics 42, no. 1 (May 15, 1997): 146–51. https://doi.org/10.1006/geno.1997.4687.
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  - Bradley, Megan S., Jennifer A. Bickhaus, Cindy L. Amundsen, Laura K. Newcomb, Tracy Truong, Alison C. Weidner, and Nazema Y. Siddiqui. “Vaginal Uterosacral Ligament Suspension: A Retrospective Cohort of Absorbable and Permanent Suture Groups..” Female Pelvic Med Reconstr Surg 24, no. 3 (n.d.): 207–12. https://doi.org/10.1097/SPV.0000000000000451.
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  - Bradley, Megan S., Marie-Helene Boudreau, Carole Grenier, Zhiqing Huang, Susan K. Murphy, and Nazema Y. Siddiqui. “Urine RNA Processing in a Clinical Setting: Comparison of 3 Protocols..” Female Pelvic Med Reconstr Surg 25, no. 3 (n.d.): 247–51. https://doi.org/10.1097/SPV.0000000000000525.
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  - Dieter, Alexis A., Jennifer M. Wu, Nazema Y. Siddiqui, Danielle J. Degoski, Jillene M. Brooks, Paul C. Dolber, and Matthew O. Fraser. “Characterizing the Bladder's Response to Onabotulinum Toxin Type A Using a Rat Model..” Female Pelvic Med Reconstr Surg 22, no. 6 (n.d.): 467–71. https://doi.org/10.1097/SPV.0000000000000316.
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  - Kisby, Cassandra K., Michael R. Polin, Anthony G. Visco, and Nazema Y. Siddiqui. “Same-Day Discharge After Robotic-Assisted Sacrocolpopexy..” Female Pelvic Med Reconstr Surg 25, no. 5 (n.d.): 337–41. https://doi.org/10.1097/SPV.0000000000000573.
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  - Siddiqui, Nazema Y., W Thomas Gregory, Victoria L. Handa, John O. L. DeLancey, Holly E. Richter, Pamela Moalli, Matthew D. Barber, et al. “American Urogynecologic Society Prolapse Consensus Conference Summary Report..” Female Pelvic Med Reconstr Surg 24, no. 4 (n.d.): 260–63. https://doi.org/10.1097/SPV.0000000000000533.
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- Conference Papers
  - Hendrickson-Cahill, W. K., L. J. Havrilesky, and N. Y. Siddiqui. “COST EFFECTIVENESS OF SELECTIVE COMPARED TO UNIVERSAL URINE SCREENING PROTOCOL PRIOR TO UROGYNECOLOGIC SURGERY.” In International Urogynecology Journal, 30:S177–78. SPRINGER LONDON LTD, 2019.
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  - Sysoeva, T. A., N. Y. Siddiqui, C. L. Amundsen, and L. Karstens. “COMPARISON OF DNA EXTRACTION KITS IN COMPOSITIONAL ANALYSES OF URINARY MICROBIOME.” In International Urogynecology Journal, 30:S355–S355. SPRINGER LONDON LTD, 2019.
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  - Vaughan, M. H., C. L. Amundsen, K. C. Hazen, and N. Y. Siddiqui. “EFFECT OF RECURRENT UTI PROPHYLAXIS ON URINARY MICROBES.” In International Urogynecology Journal, 30:S165–66. SPRINGER LONDON LTD, 2019.
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  - Vaughan, M. H., L. Giugale, N. Y. Siddiqui, and M. S. Bradley. “17: Impact of genital hiatus size on anatomic outcomes after mesh-augmented sacrospinous ligament fixation.” In American Journal of Obstetrics and Gynecology, 220:S700–701. Elsevier BV, 2019. https://doi.org/10.1016/j.ajog.2019.01.027.
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  - Vaughan, Monique H., Shunaha Kim-Fine, Kathie L. Hullfish, Tovia M. Smith, Nazema Y. Siddiqui, and Elisa R. Trowbridge. “Validation of the Simulated Vaginal Hysterectomy Trainer..” In J Minim Invasive Gynecol, 25:1101–6, 2018. https://doi.org/10.1016/j.jmig.2018.02.022.
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  - Bradley, Megan S., Emily Burke, Carole Grenier, Cindy L. Amundsen, Susan Murphy, and Nazema Y. Siddiqui. “URINARY METHYLATION PATTERNS IN WOMEN WITH INTERSTITIAL CYSTITIS/BLADDER PAIN SYNDROME.” In Neurourology and Urodynamics, 36:S17–18. WILEY-BLACKWELL, 2017.
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  - Bradley, Megan S., Marie-Helene Boudreau, Carole Grenier, Zhiqing Huang, Susan Murphy, and Nazema Y. Siddiqui. “STANDARDIZATION OF RNA PROCESSING FROM URINE SEDIMENT IN A CLINICAL SETTING.” In Neurourology and Urodynamics, 36:S18–S18. WILEY-BLACKWELL, 2017.
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  - Siddiqui, N. Y., A. A. Dieter, C. L. Amundsen, J. M. Brooks, D. J. Degoski, and M. O. Fraser. “UNDERACTIVE BLADDER IN OBESE-PRONE RATS FED A HIGH FAT DIET.” In Neurourology and Urodynamics, 33:952–53. WILEY-BLACKWELL, 2014.
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  - Dieter, A. A., J. M. Wu, N. Y. Siddiqui, D. J. Degoski, J. M. Brooks, P. C. Dolber, and M. O. Fraser. “ADEQUATE COMPENSATION? THE RESPONSE OF BLADDER SMOOTH MUSCLE TO BOTULINUM TOXIN TYPE A IN A RAT MODEL.” In International Urogynecology Journal, 25:S224–25. SPRINGER LONDON LTD, 2014.
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Teaching & Mentoring
Advising & Mentoring
- Fellows, Female Pelvic Medicine and Reconstructive Surgery
  
  Amie Kawasaki, MD 2010 - 2012
  
  Pamela Levin, MD 2010 - 2013
  
  Autumn Edenfield, MD 2011 - 2014
  
  Alexis Dieter, MD 2012 - 2015
  
  Michael Polin, MD 2013 - 2016
  
  Megan Bradley, MD 2014 - 2017
  
  Jennifer Bickhaus, MD 2015 - present
  
  Monique Vaughan, MD 2016 - present
  
  Ana Rebecca Meekins, MD 2017- present
  
  Residents, Obstetrics and Gynecology
  
  Alexis Dieter, MD 2009 - 2012
  
  Marcella Willis-Gray, MD 2011 - 2015
  
  Ana Rebecca Meekins, MD 2013 - 2017
  
  Laura Newcomb, MD 2014 - present
  
  Amy Askew, MD 2015 - present
  
   
  
  T32 Trainee
  
  Rujin Ju, MD 2012 - 2015
  
  PhD Candidates
  
  Andrew R. Hutchins 2016 - present; PhD Student, Duke University Department of Mechanical Engineering and Materials Science
  
  Jialing Mao 2018 - present; PhD Student, Duke University Department of Statistical Science (co-Mentor for Duke FORGE scholar in health data sciences)
Teaching Activities
- 1. Duke OB/GYN Residency Simulation Activities (2008-present): Faculty for 4th degree perineal laceration repair workshop (annual simulation); Faculty director for Robotic Surgery simulation training
  
  2. Duke University Nurse Practitioner Program (2008-present): Course faculty for pelvic floor disorders; annual simulation training for pessary fitting and management
  
  3, Duke Robotic Training Curriculum (2011- present): Direct and oversee comprehensive curriculum including technical skill assessment and certification for OB/GYN and Urology trainees
  
  4. Preceptor, Duke Medical School Primary Care Leadership Track (2014 - present)
  
  5. Preceptor, Duke Medical School CAPSTONE Course (2016, 2017)
  
  6. Duke Urology Trainees Basic and Clinical Research Course; course faculty 2015 - present
  
  7. Durham VA Geriatric Research, Education, and Clinical Center (GRECC) Core Curriculum; Annual lecture on Urinary Incontinence 2014 - present
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
Service to the Profession
Service to Duke
- Duke University Medical Center. Institutional Review Board. 2015 2015

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Education, Training, & Certifications

Medical Licensure

Duke Appointment History

Leadership & Clinical Positions at Duke

In the News

Awards & Honors

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

Industry Relationships

Selected Publications

Academic Articles

Conference Papers

Advising & Mentoring

Teaching Activities

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Service to Duke