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Development of dendritic form and function.

Publication ,  Journal Article
Lefebvre, JL; Sanes, JR; Kay, JN
Published in: Annu Rev Cell Dev Biol
2015

The nervous system is populated by numerous types of neurons, each bearing a dendritic arbor with a characteristic morphology. These type-specific features influence many aspects of a neuron's function, including the number and identity of presynaptic inputs and how inputs are integrated to determine firing properties. Here, we review the mechanisms that regulate the construction of cell type-specific dendrite patterns during development. We focus on four aspects of dendrite patterning that are particularly important in determining the function of the mature neuron: (a) dendrite shape, including branching pattern and geometry of the arbor; (b) dendritic arbor size;

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Published In

Annu Rev Cell Dev Biol

DOI

EISSN

1530-8995

Publication Date

2015

Volume

31

Start / End Page

741 / 777

Location

United States

Related Subject Headings

  • Humans
  • Developmental Biology
  • Dendrites
  • Chromosome Pairing
  • Animals
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Lefebvre, J. L., Sanes, J. R., & Kay, J. N. (2015). Development of dendritic form and function. Annu Rev Cell Dev Biol, 31, 741–777. https://doi.org/10.1146/annurev-cellbio-100913-013020
Lefebvre, Julie L., Joshua R. Sanes, and Jeremy N. Kay. “Development of dendritic form and function.Annu Rev Cell Dev Biol 31 (2015): 741–77. https://doi.org/10.1146/annurev-cellbio-100913-013020.
Lefebvre JL, Sanes JR, Kay JN. Development of dendritic form and function. Annu Rev Cell Dev Biol. 2015;31:741–77.
Lefebvre, Julie L., et al. “Development of dendritic form and function.Annu Rev Cell Dev Biol, vol. 31, 2015, pp. 741–77. Pubmed, doi:10.1146/annurev-cellbio-100913-013020.
Lefebvre JL, Sanes JR, Kay JN. Development of dendritic form and function. Annu Rev Cell Dev Biol. 2015;31:741–777.

Published In

Annu Rev Cell Dev Biol

DOI

EISSN

1530-8995

Publication Date

2015

Volume

31

Start / End Page

741 / 777

Location

United States

Related Subject Headings

  • Humans
  • Developmental Biology
  • Dendrites
  • Chromosome Pairing
  • Animals
  • 3101 Biochemistry and cell biology
  • 11 Medical and Health Sciences
  • 06 Biological Sciences