Overview
We study how neural circuits devoted to specific visual processing tasks arise during development of the retina, and the consequences for circuit function when development goes wrong. The tools of mouse genetics are central to our approach, and we draw on a wide range of molecular, genetic, and imaging methods.
Current Appointments & Affiliations
Associate Professor of Neurobiology
·
2020 - Present
Neurobiology,
Basic Science Departments
Associate Professor in Ophthalmology
·
2020 - Present
Ophthalmology,
Clinical Science Departments
Associate Professor in Cell Biology
·
2021 - Present
Cell Biology,
Basic Science Departments
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Microglia and Myeloid Cell Populations of the Developing Mouse Retina.
Journal Article Glia · February 2026 Microglia make important contributions to central nervous system (CNS) development, but the breadth of their distinct developmental functions remains poorly understood. The mouse retina has been a key model system for understanding fundamental mechanisms c ... Full text Link to item CiteDevelopment of Retinal Astroglia.
Journal Article Annu Rev Vis Sci · September 2025 Müller cells and retinal nerve fiber layer astrocytes are the major astroglia of the mammalian retina. They have numerous important functions in adulthood for maintaining neuronal homeostasis as well as in developing retina, where they facilitate key event ... Full text Link to item CiteLoss of MEGF10 Decreases the Number of Perisynaptic Schwann Cells and Innervation of Neuromuscular Junctions in Aging Mice.
Journal Article J Peripher Nerv Syst · March 2025 BACKGROUND AND AIMS: At the neuromuscular junction (NMJ), the synapse between motor neurons and muscle fibers, reside perisynaptic Schwann cells (PSCs) which are specialized glia that regulate the maintenance and repair of this synapse. While we know how P ... Full text Link to item CiteRecent Grants
2/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030Defining the underlying causes of retinal degeneration in CRB1 disease
ResearchPrincipal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2024 - 2029Neurobiology Training Program
Inst. Training Prgm or CMECo-Director · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029View All Grants
Education, Training & Certifications
University of California, San Francisco ·
2004
Ph.D.