Folate fortification of rice by metabolic engineering.
Publication
, Journal Article
Storozhenko, S; De Brouwer, V; Volckaert, M; Navarrete, O; Blancquaert, D; Zhang, G-F; Lambert, W; Van Der Straeten, D
Published in: Nat Biotechnol
November 2007
Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement.
Duke Scholars
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Published In
Nat Biotechnol
DOI
ISSN
1087-0156
Publication Date
November 2007
Volume
25
Issue
11
Start / End Page
1277 / 1279
Location
United States
Related Subject Headings
- Pterins
- Plants, Genetically Modified
- Oryza
- Genetic Engineering
- Genes, Plant
- Food, Fortified
- Folic Acid
- Arabidopsis
- 4-Aminobenzoic Acid
Citation
APA
Chicago
ICMJE
MLA
NLM
Storozhenko, S., De Brouwer, V., Volckaert, M., Navarrete, O., Blancquaert, D., Zhang, G.-F., … Van Der Straeten, D. (2007). Folate fortification of rice by metabolic engineering. Nat Biotechnol, 25(11), 1277–1279. https://doi.org/10.1038/nbt1351
Storozhenko, Sergei, Veerle De Brouwer, Maarten Volckaert, Oscar Navarrete, Dieter Blancquaert, Guo-Fang Zhang, Willy Lambert, and Dominique Van Der Straeten. “Folate fortification of rice by metabolic engineering.” Nat Biotechnol 25, no. 11 (November 2007): 1277–79. https://doi.org/10.1038/nbt1351.
Storozhenko S, De Brouwer V, Volckaert M, Navarrete O, Blancquaert D, Zhang G-F, et al. Folate fortification of rice by metabolic engineering. Nat Biotechnol. 2007 Nov;25(11):1277–9.
Storozhenko, Sergei, et al. “Folate fortification of rice by metabolic engineering.” Nat Biotechnol, vol. 25, no. 11, Nov. 2007, pp. 1277–79. Pubmed, doi:10.1038/nbt1351.
Storozhenko S, De Brouwer V, Volckaert M, Navarrete O, Blancquaert D, Zhang G-F, Lambert W, Van Der Straeten D. Folate fortification of rice by metabolic engineering. Nat Biotechnol. 2007 Nov;25(11):1277–1279.
Published In
Nat Biotechnol
DOI
ISSN
1087-0156
Publication Date
November 2007
Volume
25
Issue
11
Start / End Page
1277 / 1279
Location
United States
Related Subject Headings
- Pterins
- Plants, Genetically Modified
- Oryza
- Genetic Engineering
- Genes, Plant
- Food, Fortified
- Folic Acid
- Arabidopsis
- 4-Aminobenzoic Acid