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Multi-component extracellular matrices based on peptide self-assembly.

Publication ,  Journal Article
Collier, JH; Rudra, JS; Gasiorowski, JZ; Jung, JP
Published in: Chemical Society reviews
September 2010

Extracellular matrices (ECMs) are challenging design targets for materials synthesis because they serve multiple biological roles, and they are composed of multiple molecular constituents. In addition, their composition and activities are dynamic and variable between tissues, and they are difficult to study mechanistically in physiological contexts. Nevertheless, the design of synthetic ECMs is a central consideration in applications such as regenerative medicine and 3D cell culture. In order to produce synthetic matrices having both multi-component construction and high levels of compositional definition, strategies based on molecular self-assembly are receiving increasing interest. These approaches are described in this tutorial review and compared with the structures and processes in native ECMs that serve as their inspiration.

Duke Scholars

Published In

Chemical Society reviews

DOI

EISSN

1460-4744

ISSN

0306-0012

Publication Date

September 2010

Volume

39

Issue

9

Start / End Page

3413 / 3424

Related Subject Headings

  • Peptide Fragments
  • Humans
  • General Chemistry
  • Extracellular Matrix
  • Biocompatible Materials
  • Animals
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

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Collier, J. H., Rudra, J. S., Gasiorowski, J. Z., & Jung, J. P. (2010). Multi-component extracellular matrices based on peptide self-assembly. Chemical Society Reviews, 39(9), 3413–3424. https://doi.org/10.1039/b914337h
Collier, Joel H., Jai S. Rudra, Joshua Z. Gasiorowski, and Jangwook P. Jung. “Multi-component extracellular matrices based on peptide self-assembly.Chemical Society Reviews 39, no. 9 (September 2010): 3413–24. https://doi.org/10.1039/b914337h.
Collier JH, Rudra JS, Gasiorowski JZ, Jung JP. Multi-component extracellular matrices based on peptide self-assembly. Chemical Society reviews. 2010 Sep;39(9):3413–24.
Collier, Joel H., et al. “Multi-component extracellular matrices based on peptide self-assembly.Chemical Society Reviews, vol. 39, no. 9, Sept. 2010, pp. 3413–24. Epmc, doi:10.1039/b914337h.
Collier JH, Rudra JS, Gasiorowski JZ, Jung JP. Multi-component extracellular matrices based on peptide self-assembly. Chemical Society reviews. 2010 Sep;39(9):3413–3424.
Journal cover image

Published In

Chemical Society reviews

DOI

EISSN

1460-4744

ISSN

0306-0012

Publication Date

September 2010

Volume

39

Issue

9

Start / End Page

3413 / 3424

Related Subject Headings

  • Peptide Fragments
  • Humans
  • General Chemistry
  • Extracellular Matrix
  • Biocompatible Materials
  • Animals
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences