Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus.
Publication
, Journal Article
Cucchiarini, M; McNulty, AL; Mauck, RL; Setton, LA; Guilak, F; Madry, H
Published in: Osteoarthritis Cartilage
August 2016
Meniscal lesions are common problems in orthopaedic surgery and sports medicine, and injury or loss of the meniscus accelerates the onset of knee osteoarthritis (OA). Despite a variety of therapeutic options in the clinics, there is a critical need for improved treatments to enhance meniscal repair. In this regard, combining gene-, cell-, and tissue engineering-based approaches is an attractive strategy to generate novel, effective therapies to treat meniscal lesions. In the present work, we provide an overview of the tools currently available to improve meniscal repair and discuss the progress and remaining challenges for potential future translation in patients.
Duke Scholars
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Published In
Osteoarthritis Cartilage
DOI
EISSN
1522-9653
Publication Date
August 2016
Volume
24
Issue
8
Start / End Page
1330 / 1339
Location
England
Related Subject Headings
- Wound Healing
- Tissue Engineering
- Tibial Meniscus Injuries
- Meniscus
- Menisci, Tibial
- Humans
- Genetic Therapy
- Arthritis & Rheumatology
- 4207 Sports science and exercise
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Cucchiarini, M., McNulty, A. L., Mauck, R. L., Setton, L. A., Guilak, F., & Madry, H. (2016). Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus. Osteoarthritis Cartilage, 24(8), 1330–1339. https://doi.org/10.1016/j.joca.2016.03.018
Cucchiarini, M., A. L. McNulty, R. L. Mauck, L. A. Setton, F. Guilak, and H. Madry. “Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus.” Osteoarthritis Cartilage 24, no. 8 (August 2016): 1330–39. https://doi.org/10.1016/j.joca.2016.03.018.
Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus. Osteoarthritis Cartilage. 2016 Aug;24(8):1330–9.
Cucchiarini, M., et al. “Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus.” Osteoarthritis Cartilage, vol. 24, no. 8, Aug. 2016, pp. 1330–39. Pubmed, doi:10.1016/j.joca.2016.03.018.
Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus. Osteoarthritis Cartilage. 2016 Aug;24(8):1330–1339.
Published In
Osteoarthritis Cartilage
DOI
EISSN
1522-9653
Publication Date
August 2016
Volume
24
Issue
8
Start / End Page
1330 / 1339
Location
England
Related Subject Headings
- Wound Healing
- Tissue Engineering
- Tibial Meniscus Injuries
- Meniscus
- Menisci, Tibial
- Humans
- Genetic Therapy
- Arthritis & Rheumatology
- 4207 Sports science and exercise
- 3202 Clinical sciences