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Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.

Publication ,  Journal Article
Jones, DI; McGee, CE; Sample, CJ; Sempowski, GD; Pickup, DJ; Staats, HF
Published in: Clin Vaccine Immunol
July 2016

Modified vaccinia Ankara virus (MVA) is a smallpox vaccine candidate. This study was performed to determine if MVA vaccination provides long-term protection against rabbitpox virus (RPXV) challenge, an animal model of smallpox. Two doses of MVA provided 100% protection against a lethal intranasal RPXV challenge administered 9 months after vaccination.

Duke Scholars

Published In

Clin Vaccine Immunol

DOI

EISSN

1556-679X

Publication Date

July 2016

Volume

23

Issue

7

Start / End Page

648 / 651

Location

United States

Related Subject Headings

  • Vaccinia virus
  • Survival Analysis
  • Smallpox Vaccine
  • Smallpox
  • Rabbits
  • Microbiology
  • Immunology
  • Immunization Schedule
  • Female
  • Disease Models, Animal
 

Citation

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ICMJE
MLA
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Jones, D. I., McGee, C. E., Sample, C. J., Sempowski, G. D., Pickup, D. J., & Staats, H. F. (2016). Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge. Clin Vaccine Immunol, 23(7), 648–651. https://doi.org/10.1128/CVI.00216-16
Jones, Dorothy I., Charles E. McGee, Christopher J. Sample, Gregory D. Sempowski, David J. Pickup, and Herman F. Staats. “Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.Clin Vaccine Immunol 23, no. 7 (July 2016): 648–51. https://doi.org/10.1128/CVI.00216-16.
Jones DI, McGee CE, Sample CJ, Sempowski GD, Pickup DJ, Staats HF. Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge. Clin Vaccine Immunol. 2016 Jul;23(7):648–51.
Jones, Dorothy I., et al. “Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.Clin Vaccine Immunol, vol. 23, no. 7, July 2016, pp. 648–51. Pubmed, doi:10.1128/CVI.00216-16.
Jones DI, McGee CE, Sample CJ, Sempowski GD, Pickup DJ, Staats HF. Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge. Clin Vaccine Immunol. 2016 Jul;23(7):648–651.

Published In

Clin Vaccine Immunol

DOI

EISSN

1556-679X

Publication Date

July 2016

Volume

23

Issue

7

Start / End Page

648 / 651

Location

United States

Related Subject Headings

  • Vaccinia virus
  • Survival Analysis
  • Smallpox Vaccine
  • Smallpox
  • Rabbits
  • Microbiology
  • Immunology
  • Immunization Schedule
  • Female
  • Disease Models, Animal