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Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT.

Publication ,  Journal Article
Viehland, C; Keller, B; Carrasco-Zevallos, OM; Nankivil, D; Shen, L; Mangalesh, S; Viet, DT; Kuo, AN; Toth, CA; Izatt, JA
Published in: Biomed Opt Express
May 1, 2016

Current-generation software for rendering volumetric OCT data sets based on ray casting results in volume visualizations with indistinct tissue features and sub-optimal depth perception. Recent developments in hand-held and microscope-integrated intrasurgical OCT designed for real-time volumetric imaging motivate development of rendering algorithms which are both visually appealing and fast enough to support real time rendering, potentially from multiple viewpoints for stereoscopic visualization. We report on an enhanced, real time, integrated volumetric rendering pipeline which incorporates high performance volumetric median and Gaussian filtering, boundary and feature enhancement, depth encoding, and lighting into a ray casting volume rendering model. We demonstrate this improved model implemented on graphics processing unit (GPU) hardware for real-time volumetric rendering of OCT data during tissue phantom and live human surgical imaging. We show that this rendering produces enhanced 3D visualizations of pathology and intraoperative maneuvers compared to standard ray casting.

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Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

May 1, 2016

Volume

7

Issue

5

Start / End Page

1815 / 1829

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

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Viehland, C., Keller, B., Carrasco-Zevallos, O. M., Nankivil, D., Shen, L., Mangalesh, S., … Izatt, J. A. (2016). Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT. Biomed Opt Express, 7(5), 1815–1829. https://doi.org/10.1364/BOE.7.001815
Viehland, Christian, Brenton Keller, Oscar M. Carrasco-Zevallos, Derek Nankivil, Liangbo Shen, Shwetha Mangalesh, Du Tran Viet, Anthony N. Kuo, Cynthia A. Toth, and Joseph A. Izatt. “Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT.Biomed Opt Express 7, no. 5 (May 1, 2016): 1815–29. https://doi.org/10.1364/BOE.7.001815.
Viehland C, Keller B, Carrasco-Zevallos OM, Nankivil D, Shen L, Mangalesh S, et al. Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT. Biomed Opt Express. 2016 May 1;7(5):1815–29.
Viehland, Christian, et al. “Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT.Biomed Opt Express, vol. 7, no. 5, May 2016, pp. 1815–29. Pubmed, doi:10.1364/BOE.7.001815.
Viehland C, Keller B, Carrasco-Zevallos OM, Nankivil D, Shen L, Mangalesh S, Viet DT, Kuo AN, Toth CA, Izatt JA. Enhanced volumetric visualization for real time 4D intraoperative ophthalmic swept-source OCT. Biomed Opt Express. 2016 May 1;7(5):1815–1829.
Journal cover image

Published In

Biomed Opt Express

DOI

ISSN

2156-7085

Publication Date

May 1, 2016

Volume

7

Issue

5

Start / End Page

1815 / 1829

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics