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Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images.

Publication ,  Journal Article
Keller, B; Cunefare, D; Grewal, DS; Mahmoud, TH; Izatt, JA; Farsiu, S
Published in: J Biomed Opt
July 1, 2016

We introduce a metric in graph search and demonstrate its application for segmenting retinal optical coherence tomography (OCT) images of macular pathology. Our proposed “adjusted mean arc length” (AMAL) metric is an adaptation of the lowest mean arc length search technique for automated OCT segmentation. We compare this method to Dijkstra’s shortest path algorithm, which we utilized previously in our popular graph theory and dynamic programming segmentation technique. As an illustrative example, we show that AMAL-based length-adaptive segmentation outperforms the shortest path in delineating the retina/vitreous boundary of patients with full-thickness macular holes when compared with expert manual grading.

Duke Scholars

Published In

J Biomed Opt

DOI

EISSN

1560-2281

Publication Date

July 1, 2016

Volume

21

Issue

7

Start / End Page

76015

Location

United States

Related Subject Headings

  • Tomography, Optical Coherence
  • Optics
  • Macular Degeneration
  • Humans
  • Algorithms
  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry
  • 0903 Biomedical Engineering
 

Citation

APA
Chicago
ICMJE
MLA
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Keller, B., Cunefare, D., Grewal, D. S., Mahmoud, T. H., Izatt, J. A., & Farsiu, S. (2016). Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images. J Biomed Opt, 21(7), 76015. https://doi.org/10.1117/1.JBO.21.7.076015
Keller, Brenton, David Cunefare, Dilraj S. Grewal, Tamer H. Mahmoud, Joseph A. Izatt, and Sina Farsiu. “Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images.J Biomed Opt 21, no. 7 (July 1, 2016): 76015. https://doi.org/10.1117/1.JBO.21.7.076015.
Keller B, Cunefare D, Grewal DS, Mahmoud TH, Izatt JA, Farsiu S. Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images. J Biomed Opt. 2016 Jul 1;21(7):76015.
Keller, Brenton, et al. “Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images.J Biomed Opt, vol. 21, no. 7, July 2016, p. 76015. Pubmed, doi:10.1117/1.JBO.21.7.076015.
Keller B, Cunefare D, Grewal DS, Mahmoud TH, Izatt JA, Farsiu S. Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images. J Biomed Opt. 2016 Jul 1;21(7):76015.

Published In

J Biomed Opt

DOI

EISSN

1560-2281

Publication Date

July 1, 2016

Volume

21

Issue

7

Start / End Page

76015

Location

United States

Related Subject Headings

  • Tomography, Optical Coherence
  • Optics
  • Macular Degeneration
  • Humans
  • Algorithms
  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 1113 Opthalmology and Optometry
  • 0903 Biomedical Engineering